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Volumn 13, Issue 4, 2014, Pages 596-604

Effects of age, sex, and genotype on high-sensitivity metabolomic profiles in the fruit fly, Drosophila melanogaster

Author keywords

Age; Aging; Drosophila melanogaster; Genetic variation; Genotype; Heritability; Metabolomics; Sex; Systems biology

Indexed keywords

AMINO ACID DERIVATIVE; CARNITINE; GLYCEROPHOSPHOLIPID; NEUROTRANSMITTER; SUGAR; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; AMINO ACID;

EID: 84905005772     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12215     Document Type: Article
Times cited : (102)

References (48)
  • 2
    • 0001677717 scopus 로고
    • Controlling the false discovery rate - a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate - a practical and powerful approach to multiple testing. J. R. Stat. Soc. Series B Methodol. 57, 289-300.
    • (1995) J. R. Stat. Soc. Series B Methodol. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 3
    • 2342646842 scopus 로고    scopus 로고
    • LSimpute: accurate estimation of missing values in microarray data with least squares methods
    • Bo TH, Dysvik B, Jonassen I (2004) LSimpute: accurate estimation of missing values in microarray data with least squares methods. Nucleic Acids Res. 32, e34.
    • (2004) Nucleic Acids Res. , vol.32
    • Bo, T.H.1    Dysvik, B.2    Jonassen, I.3
  • 6
    • 84901823390 scopus 로고    scopus 로고
    • Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry
    • Chintapalli VR, Al Bratty M, Korzekwa D, Watson DG, Dow JA (2013) Mapping an atlas of tissue-specific Drosophila melanogaster metabolomes by high resolution mass spectrometry. PLoS ONE 8, e78066.
    • (2013) PLoS ONE , vol.8
    • Chintapalli, V.R.1    Al Bratty, M.2    Korzekwa, D.3    Watson, D.G.4    Dow, J.A.5
  • 9
    • 84888036882 scopus 로고    scopus 로고
    • Chronic caloric restriction partially protects against age-related alteration in serum metabolome
    • De Guzman JM, Ku G, Fahey R, Youm YH, Kass I, Dixit VD, Kheterpal I (2012) Chronic caloric restriction partially protects against age-related alteration in serum metabolome. Age 35, 1091-1104.
    • (2012) Age , vol.35 , pp. 1091-1104
    • De Guzman, J.M.1    Ku, G.2    Fahey, R.3    Youm, Y.H.4    Kass, I.5    Dixit, V.D.6    Kheterpal, I.7
  • 12
    • 84857782934 scopus 로고    scopus 로고
    • Acetyl-l-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the l-carnitine content in the rat heart
    • Gomez LA, Heath SH, Hagen TM (2012) Acetyl-l-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the l-carnitine content in the rat heart. Mech. Ageing Dev. 133, 99-106.
    • (2012) Mech. Ageing Dev. , vol.133 , pp. 99-106
    • Gomez, L.A.1    Heath, S.H.2    Hagen, T.M.3
  • 13
    • 72949117234 scopus 로고    scopus 로고
    • Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
    • Grandison RC, Piper MD, Partridge L (2009) Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature 462, 1061-1064.
    • (2009) Nature , vol.462 , pp. 1061-1064
    • Grandison, R.C.1    Piper, M.D.2    Partridge, L.3
  • 14
    • 0001962539 scopus 로고
    • The analysis of quantitative variation in natural populations with isofemale strains
    • Hoffmann A, Parsons P (1988) The analysis of quantitative variation in natural populations with isofemale strains. Genet. Sel. Evol. 20, 87-98.
    • (1988) Genet. Sel. Evol. , vol.20 , pp. 87-98
    • Hoffmann, A.1    Parsons, P.2
  • 16
    • 84866442827 scopus 로고    scopus 로고
    • Review: a meta-analysis of GWAS and age-associated diseases
    • Jeck WR, Siebold AP, Sharpless NE (2012) Review: a meta-analysis of GWAS and age-associated diseases. Aging Cell 11, 727-731.
    • (2012) Aging Cell , vol.11 , pp. 727-731
    • Jeck, W.R.1    Siebold, A.P.2    Sharpless, N.E.3
  • 18
    • 84864223921 scopus 로고    scopus 로고
    • Nutritional metabolomics: progress in addressing complexity in diet and health
    • Jones DP, Park Y, Ziegler TR (2012) Nutritional metabolomics: progress in addressing complexity in diet and health. Annu. Rev. Nutr. 32, 183-202.
    • (2012) Annu. Rev. Nutr. , vol.32 , pp. 183-202
    • Jones, D.P.1    Park, Y.2    Ziegler, T.R.3
  • 21
    • 84856447886 scopus 로고    scopus 로고
    • Long-term cold acclimation extends survival time at 0 degrees C and modifies the metabolomic profiles of the larvae of the fruit fly Drosophila melanogaster
    • Kostal V, Korbelova J, Rozsypal J, Zahradnickova H, Cimlova J, Tomcala A, Simek P (2011) Long-term cold acclimation extends survival time at 0 degrees C and modifies the metabolomic profiles of the larvae of the fruit fly Drosophila melanogaster. PLoS ONE 6, e25025.
    • (2011) PLoS ONE , vol.6
    • Kostal, V.1    Korbelova, J.2    Rozsypal, J.3    Zahradnickova, H.4    Cimlova, J.5    Tomcala, A.6    Simek, P.7
  • 24
    • 84155172490 scopus 로고    scopus 로고
    • Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age-related diseases
    • Mishur RJ, Rea SL (2012) Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age-related diseases. Mass Spectrom. Rev. 31, 70-95.
    • (2012) Mass Spectrom. Rev. , vol.31 , pp. 70-95
    • Mishur, R.J.1    Rea, S.L.2
  • 25
    • 84884684927 scopus 로고    scopus 로고
    • Age-induced perturbation in cell membrane phospholipid fatty acid profile of longevity-selected Drosophila melanogaster and corresponding control lines
    • Moghadam NN, Holmstrup M, Pertoldi C, Loeschcke V (2013) Age-induced perturbation in cell membrane phospholipid fatty acid profile of longevity-selected Drosophila melanogaster and corresponding control lines. Exp. Gerontol. 48, 1362-1368.
    • (2013) Exp. Gerontol. , vol.48 , pp. 1362-1368
    • Moghadam, N.N.1    Holmstrup, M.2    Pertoldi, C.3    Loeschcke, V.4
  • 27
    • 40849120422 scopus 로고    scopus 로고
    • Effects of acclimation temperature on thermal tolerance and membrane phospholipid composition in the fruit fly Drosophila melanogaster
    • Overgaard J, Tomcala A, Sorensen JG, Holmstrup M, Krogh PH, Simek P, Kostal V (2008) Effects of acclimation temperature on thermal tolerance and membrane phospholipid composition in the fruit fly Drosophila melanogaster. J. Insect Physiol. 54, 619-629.
    • (2008) J. Insect Physiol. , vol.54 , pp. 619-629
    • Overgaard, J.1    Tomcala, A.2    Sorensen, J.G.3    Holmstrup, M.4    Krogh, P.H.5    Simek, P.6    Kostal, V.7
  • 28
    • 82855167178 scopus 로고    scopus 로고
    • Extension of life span of Drosophila melanogaster by the inhibitors of tryptophan-kynurenine metabolism
    • Oxenkrug GF, Navrotskaya V, Voroboyva L, Summergrad P (2011) Extension of life span of Drosophila melanogaster by the inhibitors of tryptophan-kynurenine metabolism. Fly 5, 307-309.
    • (2011) Fly , vol.5 , pp. 307-309
    • Oxenkrug, G.F.1    Navrotskaya, V.2    Voroboyva, L.3    Summergrad, P.4
  • 29
    • 79958769272 scopus 로고    scopus 로고
    • Lipid profiles of female and male Drosophila
    • Parisi M, Li R, Oliver B (2011) Lipid profiles of female and male Drosophila. BMC Res Notes. 4, 198.
    • (2011) BMC Res Notes. , vol.4 , pp. 198
    • Parisi, M.1    Li, R.2    Oliver, B.3
  • 30
    • 77954133026 scopus 로고    scopus 로고
    • Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
    • Park JH, Wacholder S, Gail MH, Peters U, Jacobs KB, Chanock SJ, Chatterjee N (2010) Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat. Genet. 42, 570-575.
    • (2010) Nat. Genet. , vol.42 , pp. 570-575
    • Park, J.H.1    Wacholder, S.2    Gail, M.H.3    Peters, U.4    Jacobs, K.B.5    Chanock, S.J.6    Chatterjee, N.7
  • 32
  • 33
    • 84863304598 scopus 로고    scopus 로고
    • R Core Team. Vienna, Austria: R Foundation for Statistical Computing.
    • R Core Team (2013) R: A language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing.
    • (2013) R: A language and Environment for Statistical Computing
  • 36
    • 84883141759 scopus 로고    scopus 로고
    • Heritability and inter-population differences in lipid profiles of Drosophila melanogaster
    • Scheitz CJ, Guo Y, Early AM, Harshman LG, Clark AG (2013) Heritability and inter-population differences in lipid profiles of Drosophila melanogaster. PLoS ONE 8, e72726.
    • (2013) PLoS ONE , vol.8
    • Scheitz, C.J.1    Guo, Y.2    Early, A.M.3    Harshman, L.G.4    Clark, A.G.5
  • 39
    • 84874349187 scopus 로고    scopus 로고
    • High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome
    • Soltow QA, Strobel FH, Mansfield KG, Wachtman L, Park Y, Jones DP (2011) High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome. Metabolomics 9, 132-143.
    • (2011) Metabolomics , vol.9 , pp. 132-143
    • Soltow, Q.A.1    Strobel, F.H.2    Mansfield, K.G.3    Wachtman, L.4    Park, Y.5    Jones, D.P.6
  • 40
    • 84867744660 scopus 로고    scopus 로고
    • Genetic variation in metabolic phenotypes: study designs and applications
    • Suhre K, Gieger C (2012) Genetic variation in metabolic phenotypes: study designs and applications. Nat. Rev. Genet. 13, 759-769.
    • (2012) Nat. Rev. Genet. , vol.13 , pp. 759-769
    • Suhre, K.1    Gieger, C.2
  • 42
    • 66649118850 scopus 로고    scopus 로고
    • Longevity of Indy mutant Drosophila not attributable to Indy mutation
    • author reply E54.
    • Toivonen JM, Gems D, Partridge L (2009) Longevity of Indy mutant Drosophila not attributable to Indy mutation. Proc. Natl Acad. Sci. USA 106, E53; author reply E54.
    • (2009) Proc. Natl Acad. Sci. USA , vol.106
    • Toivonen, J.M.1    Gems, D.2    Partridge, L.3
  • 43
    • 84872187695 scopus 로고    scopus 로고
    • xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data
    • Article 15.
    • Uppal K, Soltow QA, Strobel FH, Pittard WS, Gernert KM, Yu T, Jones DP (2013) xMSanalyzer: automated pipeline for improved feature detection and downstream analysis of large-scale, non-targeted metabolomics data. BMC Bioinformatics 14, Article 15.
    • (2013) BMC Bioinformatics , vol.14
    • Uppal, K.1    Soltow, Q.A.2    Strobel, F.H.3    Pittard, W.S.4    Gernert, K.M.5    Yu, T.6    Jones, D.P.7
  • 44
    • 33646574628 scopus 로고    scopus 로고
    • Changes in dopamine levels and locomotor activity in response to selection on virgin lifespan in Drosophila melanogaster
    • Vermeulen CJ, Cremers TI, Westerink BH, Van De Zande L, Bijlsma R (2006) Changes in dopamine levels and locomotor activity in response to selection on virgin lifespan in Drosophila melanogaster. Mech. Ageing Dev. 127, 610-617.
    • (2006) Mech. Ageing Dev. , vol.127 , pp. 610-617
    • Vermeulen, C.J.1    Cremers, T.I.2    Westerink, B.H.3    Van De Zande, L.4    Bijlsma, R.5
  • 47
    • 67650733222 scopus 로고    scopus 로고
    • apLCMS-adaptive processing of high resolution LC/MS data
    • Yu T, Park Y, Johnson JM, Jones DP (2009) apLCMS-adaptive processing of high resolution LC/MS data. Bioinformatics 25, 1930-1936.
    • (2009) Bioinformatics , vol.25 , pp. 1930-1936
    • Yu, T.1    Park, Y.2    Johnson, J.M.3    Jones, D.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.