A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activity

Nature Communications

Volumn 7, Issue , 2016, Pages

  Boesler, Carsten ^a,d   Rigo, Norbert ^a   Anokhina, Maria M ^a   Tauchert, Marcel J ^b   Agafonov, Dmitry E ^a   Kastner, Berthold ^a   Urlaub, Henning ^a,c   Ficner, Ralf ^b   Will, Cindy L ^a   Lührmann, Reinhard ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^d Targos Molecular Pathology GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; DEAD BOX PROTEIN; PSORALEN; RNA; SMALL NUCLEAR RIBONUCLEOPROTEIN; CROSS LINKING REAGENT; DDX23 PROTEIN, HUMAN;

BIOCHEMISTRY; CATALYSIS; DATA ACQUISITION; EUKARYOTE; PROTEIN;

ARTICLE; CATALYSIS; COMPLEX FORMATION; ENZYME ACTIVITY; EUKARYOTE; GENE; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERACTIONS WITH RNA; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PROCESSING; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; RNA ANALYSIS; SACCHAROMYCES CEREVISIAE; SPLICEOSOME; BIOCATALYSIS; BIOLOGICAL MODEL; GENETICS; METABOLISM; MUTATION; TWO DIMENSIONAL GEL ELECTROPHORESIS; ULTRASTRUCTURE;

EUKARYOTA;

BIOCATALYSIS; CROSS-LINKING REAGENTS; DEAD-BOX RNA HELICASES; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; MODELS, BIOLOGICAL; MUTATION; RIBONUCLEOPROTEINS, SMALL NUCLEAR; RNA; SACCHAROMYCES CEREVISIAE; SPLICEOSOMES;

EID: 84977515240     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11997     Document Type: Article

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