메뉴 건너뛰기




Volumn 11, Issue 6, 2016, Pages

Increased CD86 but Not CD80 and PD-L1 expression on liver CD68+ cells during chronic HBV infection

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; B7 ANTIGEN; CD86 ANTIGEN; PD L1 ANTIGEN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; CD68 ANTIGEN, HUMAN; DIFFERENTIATION ANTIGEN; LEUKOCYTE ANTIGEN; PROGRAMMED DEATH 1 LIGAND 1;

EID: 84977177792     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0158265     Document Type: Article
Times cited : (27)

References (50)
  • 1
    • 84969662618 scopus 로고    scopus 로고
    • WHO MC WHO, World Health Organization
    • WHO MC (2015) Hepatitis B. WHO, World Health Organization.
    • (2015) Hepatitis B
  • 2
    • 33744808242 scopus 로고    scopus 로고
    • The immune response during hepatitis B virus infection
    • PMID: 16690908
    • Bertoletti A, Gehring AJ (2006) The immune response during hepatitis B virus infection. Journal of General Virology 87: 1439-1449. PMID: 16690908
    • (2006) Journal of General Virology , vol.87 , pp. 1439-1449
    • Bertoletti, A.1    Gehring, A.J.2
  • 3
    • 58149299723 scopus 로고    scopus 로고
    • Hepatitis B virus surface antigen impairs myeloid dendritic cell function: A possible immune escape mechanism of hepatitis B virus
    • PMID: 18624732
    • den Brouw MLO, Binda RS, van Roosmalen MH, Protzer U, Janssen HLA, van der Molen RG, et al. (2009) Hepatitis B virus surface antigen impairs myeloid dendritic cell function: a possible immune escape mechanism of hepatitis B virus. Immunology 126: 280-289. doi: 10.1111/j.1365-2567.2008.02896.x PMID: 18624732
    • (2009) Immunology , vol.126 , pp. 280-289
    • Den Brouw, M.L.O.1    Binda, R.S.2    Van Roosmalen, M.H.3    Protzer, U.4    Janssen, H.L.A.5    Van Der Molen, R.G.6
  • 4
    • 35648968689 scopus 로고    scopus 로고
    • PD-1 upregulation is associated with HBV specific T cell dysfunction in chronic hepatitis B patients
    • PMID: 17868872
    • Peng GP, Li SP, Wu W, Tan XF, Chen YQ, Chen Z (2008) PD-1 upregulation is associated with HBV specific T cell dysfunction in chronic hepatitis B patients. Molecular Immunology 45: 963-970. PMID: 17868872
    • (2008) Molecular Immunology , vol.45 , pp. 963-970
    • Peng, G.P.1    Li, S.P.2    Wu, W.3    Tan, X.F.4    Chen, Y.Q.5    Chen, Z.6
  • 6
    • 84879373530 scopus 로고    scopus 로고
    • T-cell responses in hepatitis B and C virus infection: Similarities and differences
    • Schmidt J, Blum HE, Thimme R (2013) T-cell responses in hepatitis B and C virus infection: similarities and differences. Emerging Microbes & Infections 2.
    • (2013) Emerging Microbes & Infections , vol.2
    • Schmidt, J.1    Blum, H.E.2    Thimme, R.3
  • 7
    • 84906314467 scopus 로고    scopus 로고
    • The role of Kupffer cells in hepatitis B and hepatitis C virus infections
    • PMID: 24798624
    • Boltjes A, Movita D, Boonstra A, Woltman AM (2014) The role of Kupffer cells in hepatitis B and hepatitis C virus infections. Journal of Hepatology 61: 660-671. doi: 10.1016/j.jhep.2014.04.026 PMID: 24798624
    • (2014) Journal of Hepatology , vol.61 , pp. 660-671
    • Boltjes, A.1    Movita, D.2    Boonstra, A.3    Woltman, A.M.4
  • 8
    • 84884704400 scopus 로고    scopus 로고
    • CTLA-4 and autoimmunity: New insights into the dual regulator of tolerance
    • PMID: 23851140
    • Romo-Tena J, Gomez-Martin D, Alcocer-Varela J (2013) CTLA-4 and autoimmunity: New insights into the dual regulator of tolerance. Autoimmunity Reviews 12: 1171-1176. doi: 10.1016/j.autrev.2013.07.002 PMID: 23851140
    • (2013) Autoimmunity Reviews , vol.12 , pp. 1171-1176
    • Romo-Tena, J.1    Gomez-Martin, D.2    Alcocer-Varela, J.3
  • 9
    • 33745402810 scopus 로고    scopus 로고
    • Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86
    • PMID: 16708397
    • Manzotti CN, Liu MXP, Burke F, Dussably L, Zheng Y, Sansom DM (2006) Integration of CD28 and CTLA-4 function results in differential responses of T cells to CD80 and CD86. European Journal of Immunology 36: 1413-1422. PMID: 16708397
    • (2006) European Journal of Immunology , vol.36 , pp. 1413-1422
    • Manzotti, C.N.1    Liu, M.X.P.2    Burke, F.3    Dussably, L.4    Zheng, Y.5    Sansom, D.M.6
  • 10
    • 0033770215 scopus 로고    scopus 로고
    • CD28, CTLA-4 and their ligands: Who does what and to whom?
    • PMID: 11012769
    • Sansom DM (2000) CD28, CTLA-4 and their ligands: who does what and to whom? Immunology 101: 169-177. PMID: 11012769
    • (2000) Immunology , vol.101 , pp. 169-177
    • Sansom, D.M.1
  • 11
    • 84897564116 scopus 로고    scopus 로고
    • Cutaneous T Cell Lymphoma Expresses Immunosuppressive CD80 (B7-1) Cell Surface Protein in a STAT5-Dependent Manner
    • Zhang Q, Wang HY, Wei F, Liu XB, Paterson JC, Roy D, et al. (2014) Cutaneous T Cell Lymphoma Expresses Immunosuppressive CD80 (B7-1) Cell Surface Protein in a STAT5-Dependent Manner. Journal of Immunology 192: 2913-2919.
    • (2014) Journal of Immunology , vol.192 , pp. 2913-2919
    • Zhang, Q.1    Wang, H.Y.2    Wei, F.3    Liu, X.B.4    Paterson, J.C.5    Roy, D.6
  • 13
    • 2342531103 scopus 로고    scopus 로고
    • Cross-regulation of CD86 by CD80 differentially regulates T helper responses from Mycobacterium tuberculosis secretory antigen-activated dendritic cell subsets
    • PMID: 14966193
    • Balkhi MY, Latchumanan VK, Singh B, Sharma P, Natarajan K (2004) Cross-regulation of CD86 by CD80 differentially regulates T helper responses from Mycobacterium tuberculosis secretory antigen-activated dendritic cell subsets. Journal of Leukocyte Biology 75: 874-883. PMID: 14966193
    • (2004) Journal of Leukocyte Biology , vol.75 , pp. 874-883
    • Balkhi, M.Y.1    Latchumanan, V.K.2    Singh, B.3    Sharma, P.4    Natarajan, K.5
  • 14
    • 84897530001 scopus 로고    scopus 로고
    • CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4(+) T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice
    • Maj T, Slawek A, Chelmonska-Soyta A (2014) CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4(+) T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice. Mediators of Inflammation.
    • (2014) Mediators of Inflammation
    • Maj, T.1    Slawek, A.2    Chelmonska-Soyta, A.3
  • 15
    • 0033062691 scopus 로고    scopus 로고
    • CD28/CTLA-4 and CD80/CD86 families - Signaling and function
    • PMID: 10374692
    • Slavik JM, Hutchcroft JE, Bierer BE (1999) CD28/CTLA-4 and CD80/CD86 families - Signaling and function. Immunologic Research 19: 1-24. PMID: 10374692
    • (1999) Immunologic Research , vol.19 , pp. 1-24
    • Slavik, J.M.1    Hutchcroft, J.E.2    Bierer, B.E.3
  • 16
    • 23944506272 scopus 로고    scopus 로고
    • Interleukin 12 and CD86 regulate Th1 and Th2 development induced by a range of antigen doses presented by Peyer's patch and spleen cells
    • PMID: 19003211
    • Yoshida T, Hachimura S, Ishimori M, Ise W, Totsuka M, Ametani A, et al. (2003) Interleukin 12 and CD86 regulate Th1 and Th2 development induced by a range of antigen doses presented by Peyer's patch and spleen cells. Cytotechnology 43: 81-88. doi: 10.1023/B PMID: 19003211
    • (2003) Cytotechnology , vol.43 , pp. 81-88
    • Yoshida, T.1    Hachimura, S.2    Ishimori, M.3    Ise, W.4    Totsuka, M.5    Ametani, A.6
  • 17
    • 0031024723 scopus 로고    scopus 로고
    • Different cytokine profiles of intrahepatic T cells in chronic hepatitis B and hepatitis C virus infections
    • PMID: 8978359
    • Bertoletti A, DElios MM, Boni C, DeCarli M, Zignego AL, Durazzo M, et al. (1997) Different cytokine profiles of intrahepatic T cells in chronic hepatitis B and hepatitis C virus infections. Gastroenterology 112: 193-199. PMID: 8978359
    • (1997) Gastroenterology , vol.112 , pp. 193-199
    • Bertoletti, A.1    DElios, M.M.2    Boni, C.3    DeCarli, M.4    Zignego, A.L.5    Durazzo, M.6
  • 18
    • 36349000276 scopus 로고    scopus 로고
    • The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection
    • PMID: 17924445
    • Chang JJ, Thompson AJV, Visvanathan K, Kent SJ, Cameron PU, Wightman F, et al. (2007) The phenotype of hepatitis B virus-specific T cells differ in the liver and blood in chronic hepatitis B virus infection. Hepatology 46: 1332-1340. PMID: 17924445
    • (2007) Hepatology , vol.46 , pp. 1332-1340
    • Chang, J.J.1    Thompson, A.J.V.2    Visvanathan, K.3    Kent, S.J.4    Cameron, P.U.5    Wightman, F.6
  • 19
    • 77950525439 scopus 로고    scopus 로고
    • Programmed death-1-induced interleukin-10 production by monocytes impairs CD4(+) T cell activation during HIV infection
    • PMID: 20208540
    • Said EA, Dupuy FP, Trautmann L, Zhang YW, Shi Y, El-Far M, et al. (2010) Programmed death-1-induced interleukin-10 production by monocytes impairs CD4(+) T cell activation during HIV infection. Nature Medicine 16: 452-U136. doi: 10.1038/nm.2106 PMID: 20208540
    • (2010) Nature Medicine , vol.16 , pp. 452-U136
    • Said, E.A.1    Dupuy, F.P.2    Trautmann, L.3    Zhang, Y.W.4    Shi, Y.5    El-Far, M.6
  • 20
    • 0036207926 scopus 로고    scopus 로고
    • PD-1: PD-L inhibitory pathway affects both CD4(+)and CD8(+) T cells and is overcome by IL-2
    • PMID: 11857337
    • Carter LL, Fouser LA, Jussif J, Fitz L, Deng B, Wood CR, et al. (2002) PD-1: PD-L inhibitory pathway affects both CD4(+)and CD8(+) T cells and is overcome by IL-2. European Journal of Immunology 32: 634-643. PMID: 11857337
    • (2002) European Journal of Immunology , vol.32 , pp. 634-643
    • Carter, L.L.1    Fouser, L.A.2    Jussif, J.3    Fitz, L.4    Deng, B.5    Wood, C.R.6
  • 21
    • 34250662666 scopus 로고    scopus 로고
    • Programmed death 1: A critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections
    • PMID: 19372890
    • Trautmann L, Said EA, Halwani R, Janbazian L, Chomont N, El-Far M, et al. (2007) Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections. Current Opinion in Hiv and Aids 2: 219-227. doi: 10.1097/COH.0b013e3280ebb5c9 PMID: 19372890
    • (2007) Current Opinion in Hiv and Aids , vol.2 , pp. 219-227
    • Trautmann, L.1    Said, E.A.2    Halwani, R.3    Janbazian, L.4    Chomont, N.5    El-Far, M.6
  • 22
    • 0033058997 scopus 로고    scopus 로고
    • Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure
    • PMID: 10362796
    • Leifeld L, Trautwein C, Dumoulin FL, Manns MP, Sauerbruch T, Spengler U (1999) Enhanced expression of CD80 (B7-1), CD86 (B7-2), and CD40 and their ligands CD28 and CD154 in fulminant hepatic failure. American Journal of Pathology 154: 1711-1720. PMID: 10362796
    • (1999) American Journal of Pathology , vol.154 , pp. 1711-1720
    • Leifeld, L.1    Trautwein, C.2    Dumoulin, F.L.3    Manns, M.P.4    Sauerbruch, T.5    Spengler, U.6
  • 23
    • 78651367729 scopus 로고    scopus 로고
    • Intrahepatic levels of PD-1/PD-L correlate with liver inflammation in chronic hepatitis B
    • PMID: 20661763
    • Chen J, Wang XM, Wu XJ, Wang Y, Zhao H, Shen B, et al. (2011) Intrahepatic levels of PD-1/PD-L correlate with liver inflammation in chronic hepatitis B. Inflammation Research 60: 47-53. doi: 10.1007/s00011-010-0233-1 PMID: 20661763
    • (2011) Inflammation Research , vol.60 , pp. 47-53
    • Chen, J.1    Wang, X.M.2    Wu, X.J.3    Wang, Y.4    Zhao, H.5    Shen, B.6
  • 24
    • 72949086641 scopus 로고    scopus 로고
    • Chronically Inflamed Livers Up-Regulate Expression of Inhibitory B7 Family Members
    • PMID: 19739236
    • Kassel R, Cruise MW, Iezzoni JC, Taylor NA, Pruett TL, Hahn YS (2009) Chronically Inflamed Livers Up-Regulate Expression of Inhibitory B7 Family Members. Hepatology 50: 1625-1637. doi: 10.1002/hep.23173 PMID: 19739236
    • (2009) Hepatology , vol.50 , pp. 1625-1637
    • Kassel, R.1    Cruise, M.W.2    Iezzoni, J.C.3    Taylor, N.A.4    Pruett, T.L.5    Hahn, Y.S.6
  • 25
    • 80051961168 scopus 로고    scopus 로고
    • Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma
    • PMID: 21876620
    • Wang BJ, Bao JJ, Wang JZ, Wang Y, Jiang M, Xing MY, et al. (2011) Immunostaining of PD-1/PD-Ls in liver tissues of patients with hepatitis and hepatocellular carcinoma. World Journal of Gastroenterology 17: 3322-3329. doi: 10.3748/wjg.v17.i28.3322 PMID: 21876620
    • (2011) World Journal of Gastroenterology , vol.17 , pp. 3322-3329
    • Wang, B.J.1    Bao, J.J.2    Wang, J.Z.3    Wang, Y.4    Jiang, M.5    Xing, M.Y.6
  • 26
    • 84977176242 scopus 로고    scopus 로고
    • Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B
    • Zhang WJ, Peng CH, Wan YL, Lateef SA, Zheng SS (2012) Longitudinal fluctuations in PD1 and PD-L1 expression in association with changes in anti-viral immune response in chronic hepatitis B. Bmc Gastroenterology 12.
    • (2012) Bmc Gastroenterology , vol.12
    • Zhang, W.J.1    Peng, C.H.2    Wan, Y.L.3    Lateef, S.A.4    Zheng, S.S.5
  • 27
    • 84963813024 scopus 로고    scopus 로고
    • A Potential Inhibitory Profile of Liver CD68(+) Cells during HCV Infection as Observed by an Increased CD80 and PD-L1 but Not CD86 Expression
    • Said EA, Al-Reesi I, Al-Riyami M, Al-Naamani K, Al-Sinawi S, Al-Balushi MS, et al. (2016) A Potential Inhibitory Profile of Liver CD68(+) Cells during HCV Infection as Observed by an Increased CD80 and PD-L1 but Not CD86 Expression. Plos One 11.
    • (2016) Plos One , vol.11
    • Said, E.A.1    Al-Reesi, I.2    Al-Riyami, M.3    Al-Naamani, K.4    Al-Sinawi, S.5    Al-Balushi, M.S.6
  • 28
    • 84896490614 scopus 로고    scopus 로고
    • The Portal Inflammatory Infiltrate and Ductular Reaction in Human Nonalcoholic Fatty Liver Disease
    • PMID: 24254368
    • Gadd VL, Skoien R, Powell EE, Fagan KJ, Winterford C, Horsfall L, et al. (2014) The Portal Inflammatory Infiltrate and Ductular Reaction in Human Nonalcoholic Fatty Liver Disease. Hepatology 59: 1393-1405. doi: 10.1002/hep.26937 PMID: 24254368
    • (2014) Hepatology , vol.59 , pp. 1393-1405
    • Gadd, V.L.1    Skoien, R.2    Powell, E.E.3    Fagan, K.J.4    Winterford, C.5    Horsfall, L.6
  • 29
    • 84857652138 scopus 로고    scopus 로고
    • Hepatitis B virus particles preferably induce Kupffer cells to produce TGF-beta 1 over pro-inflammatory cytokines
    • PMID: 22177317
    • Li H, Zheng HW, Chen H, Xing ZZ, You H, Cong M, et al. (2012) Hepatitis B virus particles preferably induce Kupffer cells to produce TGF-beta 1 over pro-inflammatory cytokines. Digestive and Liver Disease 44: 328-333. doi: 10.1016/j.dld.2011.11.005 PMID: 22177317
    • (2012) Digestive and Liver Disease , vol.44 , pp. 328-333
    • Li, H.1    Zheng, H.W.2    Chen, H.3    Xing, Z.Z.4    You, H.5    Cong, M.6
  • 30
    • 0031749458 scopus 로고    scopus 로고
    • Expression of co-stimulatory molecules by Kupffer cells in chronic hepatitis of hepatitis C virus etiology
    • PMID: 9620333
    • Burgio VL, Ballardini G, Artini M, Caratozzolo M, Bianchi FB, Levrero M (1998) Expression of co-stimulatory molecules by Kupffer cells in chronic hepatitis of hepatitis C virus etiology. Hepatology 27: 1600-1606. PMID: 9620333
    • (1998) Hepatology , vol.27 , pp. 1600-1606
    • Burgio, V.L.1    Ballardini, G.2    Artini, M.3    Caratozzolo, M.4    Bianchi, F.B.5    Levrero, M.6
  • 31
    • 84875053195 scopus 로고    scopus 로고
    • Portal, but not lobular, macrophages express matrix metalloproteinase-9: Association with the ductular reaction and fibrosis in chronic hepatitis C
    • PMID: 23240894
    • Gadd VL, Melino M, Roy S, Horsfall L, O'Rourke P, Williams MR, et al. (2013) Portal, but not lobular, macrophages express matrix metalloproteinase-9: association with the ductular reaction and fibrosis in chronic hepatitis C. Liver International 33: 569-579. doi: 10.1111/liv.12050 PMID: 23240894
    • (2013) Liver International , vol.33 , pp. 569-579
    • Gadd, V.L.1    Melino, M.2    Roy, S.3    Horsfall, L.4    O'Rourke, P.5    Williams, M.R.6
  • 32
    • 84875503384 scopus 로고    scopus 로고
    • The Clinical Significance of the CD163+and CD68+Macrophages in Patients with Hepatocellular Carcinoma
    • Kong LQ, Zhu XD, Xu HX, Zhang JB, Lu L, Wang WQ, et al. (2013) The Clinical Significance of the CD163+and CD68+Macrophages in Patients with Hepatocellular Carcinoma. Plos One 8.
    • (2013) Plos One , vol.8
    • Kong, L.Q.1    Zhu, X.D.2    Xu, H.X.3    Zhang, J.B.4    Lu, L.5    Wang, W.Q.6
  • 33
    • 12344253963 scopus 로고    scopus 로고
    • Histopathology and clinical correlates of end-stage hepatitis B cirrhosis: A possible mechanism to explain the response to antiviral therapy
    • PMID: 15690540
    • Sigal SH, Ala A, Ivanov K, Hossain S, Bodian C, Schiano TD, et al. (2005) Histopathology and clinical correlates of end-stage hepatitis B cirrhosis: A possible mechanism to explain the response to antiviral therapy. Liver Transplantation 11: 82-88. PMID: 15690540
    • (2005) Liver Transplantation , vol.11 , pp. 82-88
    • Sigal, S.H.1    Ala, A.2    Ivanov, K.3    Hossain, S.4    Bodian, C.5    Schiano, T.D.6
  • 34
    • 23444438877 scopus 로고    scopus 로고
    • Recombinant HBsAg inhibits LPS-induced COX-2 expression and IL-18 production by interfering with the NF kappa B pathway in a human monocytic cell line, THP-1
    • PMID: 15963597
    • Cheng JD, Imanishi H, Morisaki H, Liu WD, Nakamura H, Morisaki T, et al. (2005) Recombinant HBsAg inhibits LPS-induced COX-2 expression and IL-18 production by interfering with the NF kappa B pathway in a human monocytic cell line, THP-1. Journal of Hepatology 43: 465-471. PMID: 15963597
    • (2005) Journal of Hepatology , vol.43 , pp. 465-471
    • Cheng, J.D.1    Imanishi, H.2    Morisaki, H.3    Liu, W.D.4    Nakamura, H.5    Morisaki, T.6
  • 37
    • 84977147955 scopus 로고    scopus 로고
    • Serum and ascitic levels of macrophage migration inhibitory factor (MIF) are increased in severe acute pancreatitis
    • Sakai Y, Masamune A, Satoh A, Yamagiwa T, Shimosegawa T (2001) Serum and ascitic levels of macrophage migration inhibitory factor (MIF) are increased in severe acute pancreatitis. Gastroenterology 120: A469-A469.
    • (2001) Gastroenterology , vol.120 , pp. A469-A469
    • Sakai, Y.1    Masamune, A.2    Satoh, A.3    Yamagiwa, T.4    Shimosegawa, T.5
  • 38
    • 0027239842 scopus 로고
    • Il-10 Inhibits Macrophage Costimulatory Activity by Selectively Inhibiting the up-Regulation of B7 Expression
    • Ding L, Linsley PS, Huang LY, Germain RN, Shevach EM (1993) Il-10 Inhibits Macrophage Costimulatory Activity by Selectively Inhibiting the up-Regulation of B7 Expression. Journal of Immunology 151: 1224-1234.
    • (1993) Journal of Immunology , vol.151 , pp. 1224-1234
    • Ding, L.1    Linsley, P.S.2    Huang, L.Y.3    Germain, R.N.4    Shevach, E.M.5
  • 39
    • 84946781662 scopus 로고    scopus 로고
    • Interleukin 10 (IL-10)-mediated Immunosuppression: MARCH-I INDUCTION REGULATES ANTIGEN PRESENTATION BY MACROPHAGES BUT NOT DENDRITIC CELLS
    • PMID: 26408197
    • Mittal SK, Cho KJ, Ishido S, Roche PA (2015) Interleukin 10 (IL-10)-mediated Immunosuppression: MARCH-I INDUCTION REGULATES ANTIGEN PRESENTATION BY MACROPHAGES BUT NOT DENDRITIC CELLS. Journal of Biological Chemistry 290: 27158-27167. doi: 10.1074/jbc.M115.682708 PMID: 26408197
    • (2015) Journal of Biological Chemistry , vol.290 , pp. 27158-27167
    • Mittal, S.K.1    Cho, K.J.2    Ishido, S.3    Roche, P.A.4
  • 40
    • 40749088132 scopus 로고    scopus 로고
    • Phase II trial of B7-1 (CD-86) transduced, cultured autologous tumor cell vaccine plus subcutaneous interleukin-2 for treatment of stage IV renal cell carcinoma
    • PMID: 18157014
    • Fishman M, Hunter TB, Soliman H, Thompson P, Dunn M, Smilee R, et al. (2008) Phase II trial of B7-1 (CD-86) transduced, cultured autologous tumor cell vaccine plus subcutaneous interleukin-2 for treatment of stage IV renal cell carcinoma. Journal of Immunotherapy 31: 72-80. PMID: 18157014
    • (2008) Journal of Immunotherapy , vol.31 , pp. 72-80
    • Fishman, M.1    Hunter, T.B.2    Soliman, H.3    Thompson, P.4    Dunn, M.5    Smilee, R.6
  • 42
    • 84929603452 scopus 로고    scopus 로고
    • MPGES-1-derived PGE2 suppresses CD80 expression on tumor-associated phagocytes to inhibit anti-tumor immune responses in breast cancer
    • PMID: 25871398
    • Olesch C, Sha WX, Angioni C, Sha LK, Acaf E, Patrignani P, et al. (2015) MPGES-1-derived PGE2 suppresses CD80 expression on tumor-associated phagocytes to inhibit anti-tumor immune responses in breast cancer. Oncotarget 6: 10284-10296. PMID: 25871398
    • (2015) Oncotarget , vol.6 , pp. 10284-10296
    • Olesch, C.1    Sha, W.X.2    Angioni, C.3    Sha, L.K.4    Acaf, E.5    Patrignani, P.6
  • 43
    • 4744351642 scopus 로고    scopus 로고
    • Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: Implication of HBx in upregulation of COX-2
    • PMID: 15218507
    • Cheng ASL, Chan HLY, Leung WK, To KF, Go MYY, Chan JYH, et al. (2004) Expression of HBx and COX-2 in chronic hepatitis B, cirrhosis and hepatocellular carcinoma: implication of HBx in upregulation of COX-2. Modern Pathology 17: 1169-1179. PMID: 15218507
    • (2004) Modern Pathology , vol.17 , pp. 1169-1179
    • Cheng, A.S.L.1    Chan, H.L.Y.2    Leung, W.K.3    To, K.F.4    Go, M.Y.Y.5    Chan, J.Y.H.6
  • 44
    • 0032893728 scopus 로고    scopus 로고
    • Differential expression and modulation of costimulatory molecules CD80 and CD86 on monocytes from patients with systemic lupus erythematosus
    • PMID: 10023862
    • Liu MF, Li JS, Weng TH, Lei HY (1999) Differential expression and modulation of costimulatory molecules CD80 and CD86 on monocytes from patients with systemic lupus erythematosus. Scandinavian Journal of Immunology 49: 82-87. PMID: 10023862
    • (1999) Scandinavian Journal of Immunology , vol.49 , pp. 82-87
    • Liu, M.F.1    Li, J.S.2    Weng, T.H.3    Lei, H.Y.4
  • 45
    • 84870528809 scopus 로고    scopus 로고
    • Cytokine Levels and Histopathology in Chronic Hepatitis B and Chronic Hepatitis C
    • PMID: 23067363
    • Akcam FZ, Tigli A, Kaya O, Ciris M, Vural H (2012) Cytokine Levels and Histopathology in Chronic Hepatitis B and Chronic Hepatitis C. Journal of Interferon and Cytokine Research 32: 570-574. doi: 10.1089/jir.2012.0048 PMID: 23067363
    • (2012) Journal of Interferon and Cytokine Research , vol.32 , pp. 570-574
    • Akcam, F.Z.1    Tigli, A.2    Kaya, O.3    Ciris, M.4    Vural, H.5
  • 46
    • 84979674085 scopus 로고    scopus 로고
    • Rebamipide retards CCl4-induced hepatic fibrosis in rats: Possible role for PGE2
    • Zakaria S, El-Sisi A (2016) Rebamipide retards CCl4-induced hepatic fibrosis in rats: Possible role for PGE2. Journal of Immunotoxicology: 1-10.
    • (2016) Journal of Immunotoxicology , pp. 1-10
    • Zakaria, S.1    El-Sisi, A.2
  • 47
    • 84893487976 scopus 로고    scopus 로고
    • Angiogenic capacity of M1-and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9
    • PMID: 24174628
    • Zajac E, Schweighofer B, Kupriyanova TA, Juncker-Jensen A, Minder P, Quigley JP, et al. (2013) Angiogenic capacity of M1-and M2-polarized macrophages is determined by the levels of TIMP-1 complexed with their secreted proMMP-9. Blood 122: 4054-4067. doi: 10.1182/blood-2013-05-501494 PMID: 24174628
    • (2013) Blood , vol.122 , pp. 4054-4067
    • Zajac, E.1    Schweighofer, B.2    Kupriyanova, T.A.3    Juncker-Jensen, A.4    Minder, P.5    Quigley, J.P.6
  • 48
    • 79959382649 scopus 로고    scopus 로고
    • Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis
    • Zimmermann HW, Seidler S, Gassler N, Nattermann J, Luedde T, Trautwein C, et al. (2011) Interleukin-8 Is Activated in Patients with Chronic Liver Diseases and Associated with Hepatic Macrophage Accumulation in Human Liver Fibrosis. Plos One 6.
    • (2011) Plos One , vol.6
    • Zimmermann, H.W.1    Seidler, S.2    Gassler, N.3    Nattermann, J.4    Luedde, T.5    Trautwein, C.6
  • 49
    • 84938639027 scopus 로고    scopus 로고
    • Enhanced Levels of Interleukin-8 Are Associated with Hepatitis B Virus Infection and Resistance to Interferon-Alpha Therapy
    • PMID: 25407531
    • Yang K, Guan SH, Zhang H, Pan Y, Wu YY, Wang AH, et al. (2014) Enhanced Levels of Interleukin-8 Are Associated with Hepatitis B Virus Infection and Resistance to Interferon-Alpha Therapy. International Journal of Molecular Sciences 15: 21286-21298. doi: 10.3390/ijms151121286 PMID: 25407531
    • (2014) International Journal of Molecular Sciences , vol.15 , pp. 21286-21298
    • Yang, K.1    Guan, S.H.2    Zhang, H.3    Pan, Y.4    Wu, Y.Y.5    Wang, A.H.6
  • 50
    • 84885133701 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia
    • PMID: 23396733
    • Almajhdi FN, Al-Ahdal M, Abdo AA, Sanai FM, Al-Anazi M, Khalaf N, et al. (2013) Single nucleotide polymorphisms in CXCR1 gene and its association with hepatitis B infected patients in Saudi Arabia. Annals of Hepatology 12: 220-227. PMID: 23396733
    • (2013) Annals of Hepatology , vol.12 , pp. 220-227
    • Almajhdi, F.N.1    Al-Ahdal, M.2    Abdo, A.A.3    Sanai, F.M.4    Al-Anazi, M.5    Khalaf, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.