Endogenous hypothermic response to hypoxia reduces brain injury: Implications for modeling hypoxic-ischemic encephalopathy and therapeutic hypothermia in neonatal mice

Experimental Neurology

Volumn 283, Issue , 2016, Pages 264-275

  Reinboth, Barbara S ^a   Köster, Christian ^a   Abberger, Hanna ^a   Prager, Sebastian ^a   Bendix, Ivo ^a   Felderhoff Müser, Ursula ^a   Herz, Josephine ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Brain injury; Endogenous temperature regulation; Functional deficits; Hypoxia ischemia; Neonatal mice; Perinatal asphyxia; Therapeutic hypothermia

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BRAIN DAMAGE; BRAIN HISTOLOGY; BRAIN HYPOXIA; CAROTID ARTERY OBSTRUCTION; COGNITIVE DEFECT; CONTROLLED STUDY; CORE TEMPERATURE; ELEVATED PLUS MAZE TEST; GRAY MATTER; HIPPOCAMPUS; HYPOXIC ISCHEMIC ENCEPHALOPATHY; IMMUNOHISTOCHEMISTRY; INDUCED HYPOTHERMIA; MOUSE; NEUROPROTECTION; NEWBORN; NONHUMAN; NOVEL OBJECT RECOGNITION TEST; OLIGODENDROGLIA; OPEN FIELD TEST; PRIORITY JOURNAL; ROTAROD TEST; THERMOREGULATION; WESTERN BLOTTING; WHITE MATTER INJURY; AGE; ANALYSIS OF VARIANCE; ANIMAL; BODY TEMPERATURE; BRAIN; BRAIN INJURY; C57BL MOUSE; COMPLICATION; DISEASE MODEL; LOCOMOTION; MAZE TEST; METABOLISM; NERVE CELL; PATHOLOGY; PHYSIOLOGY; TIME FACTOR;

NERVE PROTEIN;

AGE FACTORS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; BODY TEMPERATURE; BRAIN; BRAIN INJURIES; DISEASE MODELS, ANIMAL; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; LOCOMOTION; MAZE LEARNING; MICE; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NEURONS; OLIGODENDROGLIA; TIME FACTORS;

EID: 84976873456     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2016.06.024     Document Type: Article

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