Brain cell death is reduced with cooling by 3.5°C to 5°C but increased with cooling by 8.5°C in a piglet asphyxia model

Stroke

Volumn 46, Issue 1, 2015, Pages 275-278

  Alonso Alconada, Daniel ^a   Broad, Kevin D ^a   Bainbridge, Alan ^b   Chandrasekaran, Manigandan ^a   Faulkner, Stuart D ^a   Kerenyi, Áron ^a   Hassell, Jane ^a   Rocha Ferreira, Eridan ^a   Hristova, Mariya ^a   Fleiss, Bobbi ^c   Bennett, Kate ^a   Kelen, Dorottya ^a   Cady, Ernest ^b   Gressens, Pierre ^c   Golay, Xavier ^d   Robertson, Nicola J ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

hypothermia; hypoxia ischemia, brain; neonatal encephalopathy; neuroprotection

Indexed keywords

CASPASE 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASPHYXIA; BODY TEMPERATURE; BRAIN CELL; BRAIN INJURY; CAPSULA INTERNA; CAUDATE NUCLEUS; CELL ACTIVATION; CELL DEATH; CONTROLLED STUDY; COOLING; HIPPOCAMPUS; HYPOTHERMIA; HYPOXIC ISCHEMIC ENCEPHALOPATHY; MACROPHAGE; MALE; MICROGLIA; NICK END LABELING; NONHUMAN; PIGLET; PUTAMEN; TEMPERATURE DEPENDENCE; THALAMUS; WHITE MATTER; ANIMAL; BRAIN; CELL SURVIVAL; DISEASE MODEL; INDUCED HYPOTHERMIA; PATHOLOGY; PIG; PROCEDURES;

ANIMALS; ASPHYXIA; BRAIN; CAUDATE NUCLEUS; CELL DEATH; CELL SURVIVAL; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; PUTAMEN; SWINE; THALAMUS; WHITE MATTER;

EID: 84920453080     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.114.007330     Document Type: Article

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