Interleukin-1β has trophic effects in microglia and its release is mediated by P2X7R pore

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Monif, Mastura ^a,c   Reid, Christopher A ^b   Powell, Kim L ^b   Drummond, Katherine J ^b   O'Brien, Terrence J ^b   Williams, David A ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Activation; Interleukin 1 ; Microglia; Neuroinflammation; P2X7 receptor; P2X7R pore; Proliferation

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NEUTRALIZING ANTIBODY; PURINERGIC P2X7 RECEPTOR;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ELECTRON MICROSCOPY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOCYTOSIS; IMMUNOHISTOCHEMISTRY; LYSOSOME; MICROGLIA; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RAT; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; HIPPOCAMPUS; METABOLISM; NERVE CELL; NEWBORN; SECRETION (PROCESS); SPRAGUE DAWLEY RAT;

ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; HIPPOCAMPUS; INTERLEUKIN-1BETA; MICROGLIA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2X7;

EID: 84976869195     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0621-8     Document Type: Article

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