RNA interference targeting CYP76AH1 in hairy roots of Salvia miltiorrhiza reveals its key role in the biosynthetic pathway of tanshinones

Biochemical and Biophysical Research Communications

Volumn 477, Issue 2, 2016, Pages 155-160

  Ma, Ying ^a,b   Ma, Xiao Hui ^b,c   Meng, Fan Yun ^a   Zhan, Zhi Lai ^b   Guo, Juan ^b   Huang, Lu Qi ^b  

^a BEIJING NORMAL UNIVERSITY   (China)

^b INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^c CHENGDU UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Biosynthetic pathway; Cytochrome P450; RNAi; Salvia miltiorrhiza; Tanshinones

Indexed keywords

10 HYDROXYMETHYLTETRAHYDROMITIRONE; 11 HYDROXYFERRUGINOL; 11 HYDROXYSUGIOL; 11,20 DIHYDROXYFERRUGINOL; 11,20 DIHYDROXYSUGIOL; CRYPTOTANSHINONE; CYTOCHROME P450; CYTOCHROME P450 6AH1; DIHYDROTANSHINONE; FERRUGINOL; MILTIRADIENE; MILTIRONE; SUGIOL; TANSHINONE; TANSHINONE I; TANSHINONE IIA; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG SYNTHESIS; HAIRY ROOT CULTURE; IN VIVO STUDY; MASS FRAGMENTOGRAPHY; METABOLIC ENGINEERING; NONHUMAN; PLANT METABOLISM; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SALVIA MILTIORRHIZA; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; BIOSYNTHESIS; GENE TARGETING; GENETICS; METABOLISM; PHYSIOLOGY; PLANT ROOT; PROCEDURES;

BIOSYNTHETIC PATHWAYS; CYTOCHROME P-450 ENZYME SYSTEM; DITERPENES, ABIETANE; GENE TARGETING; PLANT ROOTS; RNA INTERFERENCE; SALVIA MILTIORRHIZA;

EID: 84976638878     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.06.036     Document Type: Article

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