Epicatechin isolated from Tripterygium wilfordii extract reduces tau-GFP-induced neurotoxicity in zebrafish embryo through the activation of Nrf2

Biochemical and Biophysical Research Communications

Volumn 477, Issue 2, 2016, Pages 283-289

  Wu, Bo Kai ^a,b   Yuan, Rey Yue ^c   Chang, Yen Pu ^b   Lien, Huang Wei ^d   Chen, Ting Shou ^e   Chien, Hung Chi ^e   Tong, Tien Soung ^e   Tsai, Hui Ping ^e   Fang, Cheng Li ^e   Liao, Yung Feng ^d   Chang, Chun Che ^a   Chen, Rita P Y ^a,b   Huang, Chang Jen ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d INSTITUTE OF CELLULAR AND ORGANISMIC BIOLOGY   (Taiwan)

^e INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

Author keywords

Epicatechin; Neurotoxicity; Nrf2; Tauopathy; Tripterygium wilfordii; Zebrafish

Indexed keywords

EPICATECHIN; GREEN FLUORESCENT PROTEIN; TAU PROTEIN; TRANSCRIPTION FACTOR NRF2; TRIPTERYGIUM WILFORDII EXTRACT; CATECHIN; HYBRID PROTEIN; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, ZEBRAFISH; PLANT EXTRACT; ZEBRAFISH PROTEIN;

ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LUCIFERASE ASSAY; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PLANT STEM; PRIORITY JOURNAL; REPORTER GENE; TRIPTERYGIUM WILFORDII; ZEBRA FISH; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; NONMAMMALIAN EMBRYO; PATHOLOGY; TRIPTERYGIUM;

ANIMALS; CATECHIN; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYO, NONMAMMALIAN; GREEN FLUORESCENT PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; PLANT EXTRACTS; RECOMBINANT FUSION PROTEINS; TAU PROTEINS; TRIPTERYGIUM; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84976630275     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.06.058     Document Type: Article

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