Diallyl-disulfide, an organosulfur compound of garlic, attenuates airway inflammation via activation of the Nrf-2/HO-1 pathway and NF-kappaB suppression

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages 506-513

  Shin, In Sik ^a,b   Hong, Jumi ^a,c   Jeon, Chan Mi ^a   Shin, Na Rae ^a   Kwon, Ok Kyoung ^a   Kim, Hui Seong ^a,d   Kim, Jong Choon ^b   Oh, Sei Ryang ^a   Ahn, Kyung Seop ^a  

^a Korea Research Institute of Bioscience and Biotechnology (KRIBB)   (South Korea)

^b Chonnam National University   (South Korea)

^c Chungbuk National University   (South Korea)

^d University of Science and Technology (UST)   (South Korea)

Author keywords

Antiinflammation; Antioxidant; Asthma; Diallyl disulfide

Indexed keywords

DIALLYL DISULFIDE; GELATINASE B; HEME OXYGENASE 1; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 13; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MONTELUKAST; NITRIC OXIDE; OVALBUMIN; TRANSCRIPTION FACTOR NRF2;

ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL COUNT; CONTROLLED STUDY; DRUG DOSE COMPARISON; FEMALE; IN VIVO STUDY; LUNG FLUID; MACROPHAGE; MOUSE; MUCUS SECRETION; NONHUMAN; PROTEIN EXPRESSION; RESPIRATORY TRACT INFLAMMATION;

ALLIUM SATIVUM;

ANTIINFLAMMATION; ANTIOXIDANT; ASTHMA; DIALLYL DISULFIDE;

ALLYL COMPOUNDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELL LINE; DISEASE MODELS, ANIMAL; DISULFIDES; FEMALE; GARLIC; HEME OXYGENASE-1; INTERLEUKINS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84885067527     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.09.012     Document Type: Article

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