Coxsackievirus B3 infection induces autophagic flux, and autophagosomes are critical for efficient viral replication

Archives of Virology

Volumn 161, Issue 8, 2016, Pages 2197-2205

  Shi, Xiaodan ^a   Chen, Zijian ^a   Tang, Shengjie ^a   Wu, Fei ^a   Xiong, Sidong ^a   Dong, Chunsheng ^a  

^a SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1;

AUTOPHAGOSOME; AUTOPHAGY; COXSACKIE VIRUS INFECTION; ENTEROVIRUS B; GENETICS; HEK293 CELL LINE; HUMAN; LYSOSOME; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; VIROLOGY; VIRUS REPLICATION;

AUTOPHAGOSOMES; AUTOPHAGY; COXSACKIEVIRUS INFECTIONS; ENTEROVIRUS B, HUMAN; HEK293 CELLS; HUMANS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; LYSOSOMES; VIRUS REPLICATION;

EID: 84976618327     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00705-016-2896-6     Document Type: Article

References (30)

1. Alirezaei M, Flynn CT, Wood MR, Whitton JL (2012) Pancreatic acinar cell-specific autophagy disruption reduces coxsackievirus replication and pathogenesis in vivo. Cell Host Microbe 11:298–305
2. Cornell CT, Kiosses WB, Harkins S, Whitton JL (2006) Inhibition of protein trafficking by coxsackievirus b3: multiple viral proteins target a single organelle. J Virol 80:6637–6647
3. Feldman AM, McNamara D (2000) Myocarditis. N Engl J Med 343:1388–1398
4. Kemball CC, Alirezaei M, Flynn CT, Wood MR, Harkins S, Kiosses WB, Whitton JL (2010) Coxsackievirus infection induces autophagy-like vesicles and megaphagosomes in pancreatic acinar cells in vivo. J Virol 84:12110–12124
5. Kimura S, Noda T, Yoshimori T (2007) Dissection of the autophagosome maturation process by a novel reporter protein, tandem fluorescent-tagged LC3. Autophagy 3:452–460
6. Kirkegaard K, Taylor MP, Jackson WT (2004) Cellular autophagy: surrender, avoidance and subversion by microorganisms. Nat Rev Microbiol 2:301–314
7. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Zschocke J, Zuckerbraun B (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8:445–544
8. Krausslich HG, Nicklin MJ, Lee CK, Wimmer E (1988) Polyprotein processing in picornavirus replication. Biochimie 70:119–130
9. Kudchodkar SB, Levine B (2009) Viruses and autophagy. Rev Med Virol 19:359–378
10. Kyei GB, Dinkins C, Davis AS, Roberts E, Singh SB, Dong C, Wu L, Kominami E, Ueno T, Yamamoto A, Federico M, Panganiban A, Vergne I, Deretic V (2009) Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages. J Cell Biol 186:255–268
11. Lee YR, Hu HY, Kuo SH, Lei HY, Lin YS, Yeh TM, Liu CC, Liu HS (2013) Dengue virus infection induces autophagy: an in vivo study. J Biomed Sci 20:65
12. Lindberg AM, Stalhandske PO, Pettersson U (1987) Genome of coxsackievirus B3. Virology 156:50–63
13. Liu B, Fang M, Hu Y, Huang B, Li N, Chang C, Huang R, Xu X, Yang Z, Chen Z, Liu W (2014) Hepatitis B virus X protein inhibits autophagic degradation by impairing lysosomal maturation. Autophagy 10:416–430
14. Mizushima N, Komatsu M (2011) Autophagy: renovation of cells and tissues. Cell 147:728–741
15. Orvedahl A, Alexander D, Talloczy Z, Sun Q, Wei Y, Zhang W, Burns D, Leib DA, Levine B (2007) HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host Microbe 1:23–35
16. Palmenberg AC (1990) Proteolytic processing of picornaviral polyprotein. Annu Rev Microbiol 44:603–623
17. Pauschinger M, Phan MD, Doerner A, Kuehl U, Schwimmbeck PL, Poller W, Kandolf R, Schultheiss HP (1999) Enteroviral RNA replication in the myocardium of patients with left ventricular dysfunction and clinically suspected myocarditis. Circulation 99:889–895
18. Racaniello VR (2007) Picornaviridae: the virus and their replication. In: Knipe DM, Howley PM, Griffin DE, Lamb RA, Straus SE, Martin MA, Roizman B (eds) Fields virology, 5th edn. Lippincott, Williams & Wilkins, Philadelphia
19. Reed L, Muench H (1938) A simple method of estimating fifty per cent endpoint. Am J Hyg 27:493–497
20. Richards AL, Jackson WT (2012) Intracellular vesicle acidification promotes maturation of infectious poliovirus particles. PLoS Pathog 8:e1003046
21. Richards AL, Jackson WT (2013) How positive-strand RNA viruses benefit from autophagosome maturation. J Virol 87:9966–9972
22. Rubinsztein DC, Shpilka T, Elazar Z (2012) Mechanisms of autophagosome biogenesis. Curr Biol 22:R29–R34
23. Shi J, Wong J, Piesik P, Fung G, Zhang J, Jagdeo J, Li X, Jan E, Luo H (2013) Cleavage of sequestosome 1/p62 by an enteroviral protease results in disrupted selective autophagy and impaired NFKB signaling. Autophagy 9:1591–1603
24. Singh R, Cuervo AM (2012) Lipophagy: connecting autophagy and lipid metabolism. Int J Cell Biol 2012:282041
25. Sun MX, Huang L, Wang R, Yu YL, Li C, Li PP, Hu XC, Hao HP, Ishag HA, Mao X (2012) Porcine reproductive and respiratory syndrome virus induces autophagy to promote virus replication. Autophagy 8:1434–1447
26. Tabor-Godwin JM, Tsueng G, Sayen MR, Gottlieb RA, Feuer R (2012) The role of autophagy during coxsackievirus infection of neural progenitor and stem cells. Autophagy 8:938–953
27. Tam PE (2006) Coxsackievirus myocarditis: interplay between virus and host in the pathogenesis of heart disease. Viral Immunol 19:133–146
28. Tong L, Lin L, Zhao W, Wang B, Wu S, Liu H, Zhong X, Cui Y, Gu H, Zhang F, Zhong Z (2011) Destabilization of coxsackievirus b3 genome integrated with enhanced green fluorescent protein gene. Intervirology 54:268–275
29. Wileman T (2007) Aggresomes and pericentriolar sites of virus assembly: cellular defense or viral design? Annu Rev Microbiol 61:149–167
30. Wong J, Zhang J, Si X, Gao G, Mao I, McManus BM, Luo H (2008) Autophagosome supports coxsackievirus B3 replication in host cells. J Virol 82:9143–9153