메뉴 건너뛰기




Volumn 101, Issue 1, 2016, Pages 92-108

The hypoxia-induced dehydrogenase HorA is required for coenzyme Q10 biosynthesis, azole sensitivity and virulence of Aspergillus fumigatus

Author keywords

[No Author keywords available]

Indexed keywords

OXIDOREDUCTASE; PROTEIN HORA; PYRROLE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; UBIDECARENONE; UNCLASSIFIED DRUG;

EID: 84976570133     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/mmi.13377     Document Type: Article
Times cited : (22)

References (67)
  • 2
    • 84925308729 scopus 로고    scopus 로고
    • Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae
    • Allan, C.M., Awad, A.M., Johnson, J.S., Shirasaki, D.I., Wang, C., Blaby-Haas, C.E., et al. (2015) Identification of Coq11, a new coenzyme Q biosynthetic protein in the CoQ-synthome in Saccharomyces cerevisiae. J Biol Chem 290: 7517–7534.
    • (2015) J Biol Chem , vol.290 , pp. 7517-7534
    • Allan, C.M.1    Awad, A.M.2    Johnson, J.S.3    Shirasaki, D.I.4    Wang, C.5    Blaby-Haas, C.E.6
  • 3
    • 84856569061 scopus 로고    scopus 로고
    • Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter
    • Barker, B.M., Kroll, K., Vodisch, M., Mazurie, A., Kniemeyer, O., and Cramer, R.A. (2012) Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. BMC Genomics 13: 62.
    • (2012) BMC Genomics , vol.13 , pp. 62
    • Barker, B.M.1    Kroll, K.2    Vodisch, M.3    Mazurie, A.4    Kniemeyer, O.5    Cramer, R.A.6
  • 4
    • 84855278233 scopus 로고    scopus 로고
    • SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus
    • Blatzer, M., Barker, B.M., Willger, S.D., Beckmann, N., Blosser, S.J., Cornish, E.J., et al. (2011) SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus. PLoS Genet 7: 1.
    • (2011) PLoS Genet , vol.7 , pp. 1
    • Blatzer, M.1    Barker, B.M.2    Willger, S.D.3    Beckmann, N.4    Blosser, S.J.5    Cornish, E.J.6
  • 5
    • 84862241442 scopus 로고    scopus 로고
    • Identification of novel genes conferring altered azole susceptibility in Aspergillus fumigatus
    • Bowyer, P., Mosquera, J., Anderson, M., Birch, M., Bromley, M., and Denning, D.W. (2012) Identification of novel genes conferring altered azole susceptibility in Aspergillus fumigatus. FEMS Microbiol Lett 332: 10–19.
    • (2012) FEMS Microbiol Lett , vol.332 , pp. 10-19
    • Bowyer, P.1    Mosquera, J.2    Anderson, M.3    Birch, M.4    Bromley, M.5    Denning, D.W.6
  • 6
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford, M.M. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248–254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 7
    • 27944450041 scopus 로고    scopus 로고
    • Systemic fungal infections caused by Aspergillus species: epidemiology, infection process and virulence determinants
    • Brakhage, A.A. (2005) Systemic fungal infections caused by Aspergillus species: epidemiology, infection process and virulence determinants. Curr Drug Targets 6: 875–886.
    • (2005) Curr Drug Targets , vol.6 , pp. 875-886
    • Brakhage, A.A.1
  • 8
    • 0036405360 scopus 로고    scopus 로고
    • Menacing mold: the molecular biology of Aspergillus fumigatus
    • Brakhage, A.A., and Langfelder, K. (2002) Menacing mold: the molecular biology of Aspergillus fumigatus. Annu Rev Microbiol 56: 433–455.
    • (2002) Annu Rev Microbiol , vol.56 , pp. 433-455
    • Brakhage, A.A.1    Langfelder, K.2
  • 9
    • 0029072701 scopus 로고
    • Use of reporter genes to identify recessive trans-acting mutations specifically involved in the regulation of Aspergillus nidulans penicillin biosynthesis genes
    • Brakhage, A.A., and Van den Brulle, J. (1995) Use of reporter genes to identify recessive trans-acting mutations specifically involved in the regulation of Aspergillus nidulans penicillin biosynthesis genes. J Bacteriol 177: 2781–2788.
    • (1995) J Bacteriol , vol.177 , pp. 2781-2788
    • Brakhage, A.A.1    Van den Brulle, J.2
  • 10
    • 0024462097 scopus 로고
    • Electron-transfer restoration by vitamin K3 in a complex III-deficient mutant of S. cerevisiae and sequence of the corresponding cytochrome b mutation
    • Brivet-Chevillotte, P., and di Rago, J.P. (1989) Electron-transfer restoration by vitamin K3 in a complex III-deficient mutant of S. cerevisiae and sequence of the corresponding cytochrome b mutation. FEBS Lett 255: 5–9.
    • (1989) FEBS Lett , vol.255 , pp. 5-9
    • Brivet-Chevillotte, P.1    di Rago, J.P.2
  • 11
    • 84901816030 scopus 로고    scopus 로고
    • Are mitochondria the Achilles' heel of the Kingdom Fungi?
    • Chatre, L., and Ricchetti, M. (2014) Are mitochondria the Achilles' heel of the Kingdom Fungi? Curr Opin Microbiol 20: 49–54.
    • (2014) Curr Opin Microbiol , vol.20 , pp. 49-54
    • Chatre, L.1    Ricchetti, M.2
  • 12
    • 84912121231 scopus 로고    scopus 로고
    • ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence
    • Chung, D., Barker, B.M., Carey, C.C., Merriman, B., Werner, E.R., Lechner, B.E., et al. (2014) ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence. PLoS Pathogens 10(11): e1004576.
    • (2014) PLoS Pathogens , vol.10 , Issue.11
    • Chung, D.1    Barker, B.M.2    Carey, C.C.3    Merriman, B.4    Werner, E.R.5    Lechner, B.E.6
  • 13
    • 30944449630 scopus 로고    scopus 로고
    • The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus
    • da Silva Ferreira, M.E., Kress, M.R., Savoldi, M., Goldman, M.H., Hartl, A., Heinekamp, T., et al. (2006) The akuB(KU80) mutant deficient for nonhomologous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus. Eukaryot Cell 5: 207–211.
    • (2006) Eukaryot Cell , vol.5 , pp. 207-211
    • da Silva Ferreira, M.E.1    Kress, M.R.2    Savoldi, M.3    Goldman, M.H.4    Hartl, A.5    Heinekamp, T.6
  • 15
    • 77956171147 scopus 로고    scopus 로고
    • NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
    • Dinkova-Kostova, A.T., and Talalay, P. (2010) NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector. Arch Biochem Biophys 501: 116–123.
    • (2010) Arch Biochem Biophys , vol.501 , pp. 116-123
    • Dinkova-Kostova, A.T.1    Talalay, P.2
  • 16
    • 0033006852 scopus 로고    scopus 로고
    • Ku, a DNA repair protein with multiple cellular functions?
    • Featherstone, C., and Jackson, S.P. (1999) Ku, a DNA repair protein with multiple cellular functions? Mutat Res 434: 3–15.
    • (1999) Mutat Res , vol.434 , pp. 3-15
    • Featherstone, C.1    Jackson, S.P.2
  • 19
    • 84859440628 scopus 로고    scopus 로고
    • Aspergillus fumigatus mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis
    • Grahl, N., Dinamarco, T.M., Willger, S.D., Goldman, G.H., and Cramer, R.A. (2012) Aspergillus fumigatus mitochondrial electron transport chain mediates oxidative stress homeostasis, hypoxia responses and fungal pathogenesis. Mol Microbiol 84: 383–399.
    • (2012) Mol Microbiol , vol.84 , pp. 383-399
    • Grahl, N.1    Dinamarco, T.M.2    Willger, S.D.3    Goldman, G.H.4    Cramer, R.A.5
  • 20
    • 79960941562 scopus 로고    scopus 로고
    • In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis
    • Grahl, N., Puttikamonkul, S., Macdonald, J.M., Gamcsik, M.P., Ngo, L.Y., Hohl, T.M., and Cramer, R.A. (2011) In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis. PLoS Pathog 7: 21.
    • (2011) PLoS Pathog , vol.7 , pp. 21
    • Grahl, N.1    Puttikamonkul, S.2    Macdonald, J.M.3    Gamcsik, M.P.4    Ngo, L.Y.5    Hohl, T.M.6    Cramer, R.A.7
  • 21
    • 33745628757 scopus 로고    scopus 로고
    • Generation of superoxide by the mitochondrial Complex I
    • Grivennikova, V.G., and Vinogradov, A.D. (2006) Generation of superoxide by the mitochondrial Complex I. Biochim Biophys Acta 1757: 553–561.
    • (2006) Biochim Biophys Acta , vol.1757 , pp. 553-561
    • Grivennikova, V.G.1    Vinogradov, A.D.2
  • 22
    • 77950806408 scopus 로고    scopus 로고
    • New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0
    • Guindon, S., Dufayard, J.F., Lefort, V., Anisimova, M., Hordijk, W., and Gascuel, O. (2010) New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0. Syst Biol 59: 307–321.
    • (2010) Syst Biol , vol.59 , pp. 307-321
    • Guindon, S.1    Dufayard, J.F.2    Lefort, V.3    Anisimova, M.4    Hordijk, W.5    Gascuel, O.6
  • 23
    • 79953306267 scopus 로고    scopus 로고
    • NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels
    • Haefeli, R.H., Erb, M., Gemperli, A.C., Robay, D., Courdier Fruh, I., Anklin, C., et al. (2011) NQO1-dependent redox cycling of idebenone: effects on cellular redox potential and energy levels. PLoS One 6: 0017963.
    • (2011) PLoS One , vol.6
    • Haefeli, R.H.1    Erb, M.2    Gemperli, A.C.3    Robay, D.4    Courdier Fruh, I.5    Anklin, C.6
  • 24
    • 84904995338 scopus 로고    scopus 로고
    • The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus
    • Hillmann, F., Linde, J., Beckmann, N., Cyrulies, M., Strassburger, M., Heinekamp, T., et al. (2014) The novel globin protein fungoglobin is involved in low oxygen adaptation of Aspergillus fumigatus. Mol Microbiol 93: 539–553.
    • (2014) Mol Microbiol , vol.93 , pp. 539-553
    • Hillmann, F.1    Linde, J.2    Beckmann, N.3    Cyrulies, M.4    Strassburger, M.5    Heinekamp, T.6
  • 25
    • 53049099032 scopus 로고    scopus 로고
    • Importance of mitochondria in survival of Cryptococcus neoformans under low oxygen conditions and tolerance to cobalt chloride
    • Ingavale, S.S., Chang, Y.C., Lee, H., McClelland, C.M., Leong, M.L., and Kwon-Chung, K.J. (2008) Importance of mitochondria in survival of Cryptococcus neoformans under low oxygen conditions and tolerance to cobalt chloride. PLoS Pathog 4: 1000155.
    • (2008) PLoS Pathog , vol.4 , pp. 1000155
    • Ingavale, S.S.1    Chang, Y.C.2    Lee, H.3    McClelland, C.M.4    Leong, M.L.5    Kwon-Chung, K.J.6
  • 26
    • 77953927869 scopus 로고    scopus 로고
    • Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence
    • Jacobsen, I.D., Grosse, K., Slesiona, S., Hube, B., Berndt, A., and Brock, M. (2010) Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun 78: 2995–3006.
    • (2010) Infect Immun , vol.78 , pp. 2995-3006
    • Jacobsen, I.D.1    Grosse, K.2    Slesiona, S.3    Hube, B.4    Berndt, A.5    Brock, M.6
  • 27
    • 27144435897 scopus 로고    scopus 로고
    • Effects of hypoxia on the alveolar epithelium
    • Jain, M., and Sznajder, J.I. (2005) Effects of hypoxia on the alveolar epithelium. Proc Am Thorac Soc 2: 202–205.
    • (2005) Proc Am Thorac Soc , vol.2 , pp. 202-205
    • Jain, M.1    Sznajder, J.I.2
  • 28
    • 25844520458 scopus 로고    scopus 로고
    • Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
    • Jezek, P., and Hlavata, L. (2005) Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int J Biochem Cell Biol 37: 2478–2503.
    • (2005) Int J Biochem Cell Biol , vol.37 , pp. 2478-2503
    • Jezek, P.1    Hlavata, L.2
  • 29
    • 33644560315 scopus 로고    scopus 로고
    • Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungus Aspergillus fumigatus
    • Kniemeyer, O., Lessing, F., Scheibner, O., Hertweck, C., and Brakhage, A.A. (2006) Optimisation of a 2-D gel electrophoresis protocol for the human-pathogenic fungus Aspergillus fumigatus. Curr Genet 49: 178–189.
    • (2006) Curr Genet , vol.49 , pp. 178-189
    • Kniemeyer, O.1    Lessing, F.2    Scheibner, O.3    Hertweck, C.4    Brakhage, A.A.5
  • 30
    • 33748663951 scopus 로고    scopus 로고
    • Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model
    • Kupfahl, C., Heinekamp, T., Geginat, G., Ruppert, T., Hartl, A., Hof, H., and Brakhage, A.A. (2006) Deletion of the gliP gene of Aspergillus fumigatus results in loss of gliotoxin production but has no effect on virulence of the fungus in a low-dose mouse infection model. Mol Microbiol 62: 292–302.
    • (2006) Mol Microbiol , vol.62 , pp. 292-302
    • Kupfahl, C.1    Heinekamp, T.2    Geginat, G.3    Ruppert, T.4    Hartl, A.5    Hof, H.6    Brakhage, A.A.7
  • 31
    • 78651446490 scopus 로고    scopus 로고
    • Simultaneous isolation of pure and intact chloroplasts and mitochondria from moss as the basis for sub-cellular proteomics
    • Lang, E.G., Mueller, S.J., Hoernstein, S.N., Porankiewicz-Asplund, J., Vervliet-Scheebaum, M., and Reski, R. (2011) Simultaneous isolation of pure and intact chloroplasts and mitochondria from moss as the basis for sub-cellular proteomics. Plant Cell Rep 30: 205–215.
    • (2011) Plant Cell Rep , vol.30 , pp. 205-215
    • Lang, E.G.1    Mueller, S.J.2    Hoernstein, S.N.3    Porankiewicz-Asplund, J.4    Vervliet-Scheebaum, M.5    Reski, R.6
  • 32
    • 84907605368 scopus 로고    scopus 로고
    • Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence
    • Lapp, K., Vodisch, M., Kroll, K., Strassburger, M., Kniemeyer, O., Heinekamp, T., and Brakhage, A.A. (2014) Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence. Front Microbiol 5: 469.
    • (2014) Front Microbiol , vol.5 , pp. 469
    • Lapp, K.1    Vodisch, M.2    Kroll, K.3    Strassburger, M.4    Kniemeyer, O.5    Heinekamp, T.6    Brakhage, A.A.7
  • 34
  • 35
    • 4544226575 scopus 로고    scopus 로고
    • The cyclic AMP-dependent protein kinase a network regulates development and virulence in Aspergillus fumigatus
    • Liebmann, B., Muller, M., Braun, A., and Brakhage, A.A. (2004) The cyclic AMP-dependent protein kinase a network regulates development and virulence in Aspergillus fumigatus. Infect Immun 72: 5193–5203.
    • (2004) Infect Immun , vol.72 , pp. 5193-5203
    • Liebmann, B.1    Muller, M.2    Braun, A.3    Brakhage, A.A.4
  • 36
    • 84855871849 scopus 로고    scopus 로고
    • Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach
    • Linde, J., Hortschansky, P., Fazius, E., Brakhage, A., Guthke, R., and Haas, H. (2012) Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach. BMC Syst Biol 6: 6.
    • (2012) BMC Syst Biol , vol.6 , pp. 6
    • Linde, J.1    Hortschansky, P.2    Fazius, E.3    Brakhage, A.4    Guthke, R.5    Haas, H.6
  • 37
    • 42149129009 scopus 로고    scopus 로고
    • The sho1 sensor regulates growth, morphology, and oxidant adaptation in Aspergillus fumigatus but is not essential for development of invasive pulmonary aspergillosis
    • Ma, Y., Qiao, J., Liu, W., Wan, Z., Wang, X., Calderone, R., and Li, R. (2008) The sho1 sensor regulates growth, morphology, and oxidant adaptation in Aspergillus fumigatus but is not essential for development of invasive pulmonary aspergillosis. Infect Immun 76: 1695–1701.
    • (2008) Infect Immun , vol.76 , pp. 1695-1701
    • Ma, Y.1    Qiao, J.2    Liu, W.3    Wan, Z.4    Wang, X.5    Calderone, R.6    Li, R.7
  • 38
    • 0036724743 scopus 로고    scopus 로고
    • Antifungal drug resistance to azoles and polyenes
    • Masia Canuto, M., and Gutierrez Rodero, F. (2002) Antifungal drug resistance to azoles and polyenes. Lancet Infect Dis 2: 550–563.
    • (2002) Lancet Infect Dis , vol.2 , pp. 550-563
    • Masia Canuto, M.1    Gutierrez Rodero, F.2
  • 39
    • 0035949539 scopus 로고    scopus 로고
    • Ubiquinone biosynthesis in microorganisms
    • Meganathan, R. (2001) Ubiquinone biosynthesis in microorganisms. FEMS Microbiol Lett 203: 131–139.
    • (2001) FEMS Microbiol Lett , vol.203 , pp. 131-139
    • Meganathan, R.1
  • 40
    • 0035896557 scopus 로고    scopus 로고
    • Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans
    • Miyadera, H., Amino, H., Hiraishi, A., Taka, H., Murayama, K., Miyoshi, H., et al. (2001) Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans. J Biol Chem 276: 7713–7716.
    • (2001) J Biol Chem , vol.276 , pp. 7713-7716
    • Miyadera, H.1    Amino, H.2    Hiraishi, A.3    Taka, H.4    Murayama, K.5    Miyoshi, H.6
  • 41
    • 84858994921 scopus 로고    scopus 로고
    • A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin
    • Monteiro, M.C., de la Cruz, M., Cantizani, J., Moreno, C., Tormo, J.R., Mellado, E., et al. (2012) A new approach to drug discovery: high-throughput screening of microbial natural extracts against Aspergillus fumigatus using resazurin. J Biomol Screening 17: 542–549.
    • (2012) J Biomol Screening , vol.17 , pp. 542-549
    • Monteiro, M.C.1    de la Cruz, M.2    Cantizani, J.3    Moreno, C.4    Tormo, J.R.5    Mellado, E.6
  • 42
    • 58249093939 scopus 로고    scopus 로고
    • How mitochondria produce reactive oxygen species
    • Murphy, M.P. (2009) How mitochondria produce reactive oxygen species. Biochem J 417: 1–13.
    • (2009) Biochem J , vol.417 , pp. 1-13
    • Murphy, M.P.1
  • 43
    • 84983143318 scopus 로고    scopus 로고
    • Mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus: therapeutic and evolutionary implications
    • Neubauer, M., Zhu, Z., Penka, M., Helmschrott, C., Wagener, N., and Wagener, J. (2015) Mitochondrial dynamics in the pathogenic mold Aspergillus fumigatus: therapeutic and evolutionary implications. Mol Microbiol 98: 930–945.
    • (2015) Mol Microbiol , vol.98 , pp. 930-945
    • Neubauer, M.1    Zhu, Z.2    Penka, M.3    Helmschrott, C.4    Wagener, N.5    Wagener, J.6
  • 44
    • 0014424726 scopus 로고
    • Effect of menadione on the electron transport pathway of yeast mitochondria
    • Nosoh, Y., Kajioka, J., and Itoh, M. (1968) Effect of menadione on the electron transport pathway of yeast mitochondria. Arch Biochem Biophys 127: 1–6.
    • (1968) Arch Biochem Biophys , vol.127 , pp. 1-6
    • Nosoh, Y.1    Kajioka, J.2    Itoh, M.3
  • 45
    • 84865285771 scopus 로고    scopus 로고
    • Relationship between respiration deficiency and azole resistance in clinical Candida glabrata
    • Peng, Y., Dong, D., Jiang, C., Yu, B., Wang, X., and Ji, Y. (2012) Relationship between respiration deficiency and azole resistance in clinical Candida glabrata. FEMS Yeast Res 12: 719–727.
    • (2012) FEMS Yeast Res , vol.12 , pp. 719-727
    • Peng, Y.1    Dong, D.2    Jiang, C.3    Yu, B.4    Wang, X.5    Ji, Y.6
  • 46
    • 34547759757 scopus 로고    scopus 로고
    • Invasive fungal infections in allogeneic and autologous stem cell transplant recipients: a single-center study of 166 transplanted patients
    • Post, M.J., Lass-Floerl, C., Gastl, G., and Nachbaur, D. (2007) Invasive fungal infections in allogeneic and autologous stem cell transplant recipients: a single-center study of 166 transplanted patients. Transpl Infect Dis 9: 189–195.
    • (2007) Transpl Infect Dis , vol.9 , pp. 189-195
    • Post, M.J.1    Lass-Floerl, C.2    Gastl, G.3    Nachbaur, D.4
  • 47
    • 79952039532 scopus 로고    scopus 로고
    • FungiFun: a web-based application for functional categorization of fungal genes and proteins
    • Priebe, S., Linde, J., Albrecht, D., Guthke, R., and Brakhage, A.A. (2011) FungiFun: a web-based application for functional categorization of fungal genes and proteins. Fungal Genet Biol 48: 353–358.
    • (2011) Fungal Genet Biol , vol.48 , pp. 353-358
    • Priebe, S.1    Linde, J.2    Albrecht, D.3    Guthke, R.4    Brakhage, A.A.5
  • 48
    • 59249085255 scopus 로고    scopus 로고
    • A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus
    • Richie, D.L., Hartl, L., Aimanianda, V., Winters, M.S., Fuller, K.K., Miley, M.D., et al. (2009) A role for the unfolded protein response (UPR) in virulence and antifungal susceptibility in Aspergillus fumigatus. PLoS Pathog 5: e1000258.
    • (2009) PLoS Pathog , vol.5
    • Richie, D.L.1    Hartl, L.2    Aimanianda, V.3    Winters, M.S.4    Fuller, K.K.5    Miley, M.D.6
  • 49
    • 0142248154 scopus 로고    scopus 로고
    • Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae
    • Rosenfeld, E., and Beauvoit, B. (2003) Role of the non-respiratory pathways in the utilization of molecular oxygen by Saccharomyces cerevisiae. Yeast (Chichester, England) 20: 1115–1144.
    • (2003) Yeast (Chichester, England) , vol.20 , pp. 1115-1144
    • Rosenfeld, E.1    Beauvoit, B.2
  • 50
    • 0029927505 scopus 로고    scopus 로고
    • Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels
    • Shevchenko, A., Wilm, M., Vorm, O., and Mann, M. (1996) Mass spectrometric sequencing of proteins silver-stained polyacrylamide gels. Anal Chem 68: 850–858.
    • (1996) Anal Chem , vol.68 , pp. 850-858
    • Shevchenko, A.1    Wilm, M.2    Vorm, O.3    Mann, M.4
  • 51
    • 80055116385 scopus 로고    scopus 로고
    • Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy
    • Shingu-Vazquez, M., and Traven, A. (2011) Mitochondria and fungal pathogenesis: drug tolerance, virulence, and potential for antifungal therapy. Eukaryot Cell 10: 1376–1383.
    • (2011) Eukaryot Cell , vol.10 , pp. 1376-1383
    • Shingu-Vazquez, M.1    Traven, A.2
  • 52
    • 20644463910 scopus 로고    scopus 로고
    • Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders
    • Shneyvays, V., Leshem, D., Shmist, Y., Zinman, T., and Shainberg, A. (2005) Effects of menadione and its derivative on cultured cardiomyocytes with mitochondrial disorders. J Mol Cell Cardiol 39: 149–158.
    • (2005) J Mol Cell Cardiol , vol.39 , pp. 149-158
    • Shneyvays, V.1    Leshem, D.2    Shmist, Y.3    Zinman, T.4    Shainberg, A.5
  • 54
    • 84863001304 scopus 로고    scopus 로고
    • Comparative lipidomics in clinical isolates of Candida albicans reveal crosstalk between mitochondria, cell wall integrity and azole resistance
    • Singh, A., Yadav, V., and Prasad, R. (2012) Comparative lipidomics in clinical isolates of Candida albicans reveal crosstalk between mitochondria, cell wall integrity and azole resistance. PLoS One 7: 27.
    • (2012) PLoS One , vol.7
    • Singh, A.1    Yadav, V.2    Prasad, R.3
  • 55
    • 84865826544 scopus 로고    scopus 로고
    • Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells
    • Spinazzi, M., Casarin, A., Pertegato, V., Salviati, L., and Angelini, C. (2012) Assessment of mitochondrial respiratory chain enzymatic activities on tissues and cultured cells. Nat Protoc 7: 1235–1246.
    • (2012) Nat Protoc , vol.7 , pp. 1235-1246
    • Spinazzi, M.1    Casarin, A.2    Pertegato, V.3    Salviati, L.4    Angelini, C.5
  • 56
    • 77953515722 scopus 로고    scopus 로고
    • Conserved regulators of mating are essential for Aspergillus fumigatus cleistothecium formation
    • Szewczyk, E., and Krappmann, S. (2010) Conserved regulators of mating are essential for Aspergillus fumigatus cleistothecium formation. Eukaryot Cell 9: 774–783.
    • (2010) Eukaryot Cell , vol.9 , pp. 774-783
    • Szewczyk, E.1    Krappmann, S.2
  • 57
    • 77954354972 scopus 로고    scopus 로고
    • Proteome profiling and functional classification of intracellular proteins from conidia of the human-pathogenic mold Aspergillus fumigatus
    • Teutschbein, J., Albrecht, D., Potsch, M., Guthke, R., Aimanianda, V., Clavaud, C., et al. (2010) Proteome profiling and functional classification of intracellular proteins from conidia of the human-pathogenic mold Aspergillus fumigatus. J Proteome Res 9: 3427–3442.
    • (2010) J Proteome Res , vol.9 , pp. 3427-3442
    • Teutschbein, J.1    Albrecht, D.2    Potsch, M.3    Guthke, R.4    Aimanianda, V.5    Clavaud, C.6
  • 58
    • 33645222762 scopus 로고    scopus 로고
    • Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast
    • Todd, B.L., Stewart, E.V., Burg, J.S., Hughes, A.L., and Espenshade, P.J. (2006) Sterol regulatory element binding protein is a principal regulator of anaerobic gene expression in fission yeast. Mol Cell Biol 26: 2817–2831.
    • (2006) Mol Cell Biol , vol.26 , pp. 2817-2831
    • Todd, B.L.1    Stewart, E.V.2    Burg, J.S.3    Hughes, A.L.4    Espenshade, P.J.5
  • 59
    • 34248195476 scopus 로고    scopus 로고
    • Endogenous synthesis of coenzyme Q in eukaryotes
    • Tran, U.C., and Clarke, C.F. (2007) Endogenous synthesis of coenzyme Q in eukaryotes. Mitochondrion 7 (Suppl): S62–S71.
    • (2007) Mitochondrion , vol.7 , pp. S62-S71
    • Tran, U.C.1    Clarke, C.F.2
  • 60
    • 52749097035 scopus 로고    scopus 로고
    • Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules
    • Turatsinze, J.V., Thomas-Chollier, M., Defrance, M., and van Helden, J. (2008) Using RSAT to scan genome sequences for transcription factor binding sites and cis-regulatory modules. Nat Protoc 3: 1578–1588.
    • (2008) Nat Protoc , vol.3 , pp. 1578-1588
    • Turatsinze, J.V.1    Thomas-Chollier, M.2    Defrance, M.3    van Helden, J.4
  • 61
    • 22444433317 scopus 로고    scopus 로고
    • The 29.9 kDa subunit of mitochondrial complex I is involved in the enzyme active/de-active transitions
    • Ushakova, A.V., Duarte, M., Vinogradov, A.D., and Videira, A. (2005) The 29.9 kDa subunit of mitochondrial complex I is involved in the enzyme active/de-active transitions. J Mol Biol 351: 327–333.
    • (2005) J Mol Biol , vol.351 , pp. 327-333
    • Ushakova, A.V.1    Duarte, M.2    Vinogradov, A.D.3    Videira, A.4
  • 62
    • 41649089725 scopus 로고    scopus 로고
    • The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response
    • Valiante, V., Heinekamp, T., Jain, R., Hartl, A., and Brakhage, A.A. (2008) The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response. Fungal Genet Biol 45: 618–627.
    • (2008) Fungal Genet Biol , vol.45 , pp. 618-627
    • Valiante, V.1    Heinekamp, T.2    Jain, R.3    Hartl, A.4    Brakhage, A.A.5
  • 63
    • 63049083694 scopus 로고    scopus 로고
    • Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus
    • Vödisch, M., Albrecht, D., Lessing, F., Schmidt, A.D., Winkler, R., Guthke, R., et al. (2009) Two-dimensional proteome reference maps for the human pathogenic filamentous fungus Aspergillus fumigatus. Proteomics 9: 1407–1415.
    • (2009) Proteomics , vol.9 , pp. 1407-1415
    • Vödisch, M.1    Albrecht, D.2    Lessing, F.3    Schmidt, A.D.4    Winkler, R.5    Guthke, R.6
  • 64
    • 79955799255 scopus 로고    scopus 로고
    • Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia
    • Vodisch, M., Scherlach, K., Winkler, R., Hertweck, C., Braun, H.P., Roth, M., et al. (2011) Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. J Proteome Res 10: 2508–2524.
    • (2011) J Proteome Res , vol.10 , pp. 2508-2524
    • Vodisch, M.1    Scherlach, K.2    Winkler, R.3    Hertweck, C.4    Braun, H.P.5    Roth, M.6
  • 65
    • 0028787643 scopus 로고
    • Conversion of a nonprocessed mitochondrial precursor protein into one that is processed by the mitochondrial processing peptidase
    • Waltner, M., and Weiner, H. (1995) Conversion of a nonprocessed mitochondrial precursor protein into one that is processed by the mitochondrial processing peptidase. J Biol Chem 270: 26311–26317.
    • (1995) J Biol Chem , vol.270 , pp. 26311-26317
    • Waltner, M.1    Weiner, H.2
  • 66
    • 0031861605 scopus 로고    scopus 로고
    • Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5′-monophosphate decarboxylase
    • Weidner, G., d'Enfert, C., Koch, A., Mol, P.C., and Brakhage, A.A. (1998) Development of a homologous transformation system for the human pathogenic fungus Aspergillus fumigatus based on the pyrG gene encoding orotidine 5′-monophosphate decarboxylase. Curr Genet 33: 378–385.
    • (1998) Curr Genet , vol.33 , pp. 378-385
    • Weidner, G.1    d'Enfert, C.2    Koch, A.3    Mol, P.C.4    Brakhage, A.A.5
  • 67
    • 33746872494 scopus 로고    scopus 로고
    • A rapid and sensitive LC-MS/MS method for determination of coenzyme Q10 in tobacco (Nicotiana tabacum L.) leaves
    • Zu, Y., Zhao, C., Li, C., and Zhang, L. (2006) A rapid and sensitive LC-MS/MS method for determination of coenzyme Q10 in tobacco (Nicotiana tabacum L.) leaves. J Sep Sci 29: 1607–1612.
    • (2006) J Sep Sci , vol.29 , pp. 1607-1612
    • Zu, Y.1    Zhao, C.2    Li, C.3    Zhang, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.