-
1
-
-
0033932001
-
Recovery, persistence, and sequelae in hepatitis C virus infection: A perspective on long-term outcome
-
Alter, H. J. & Seeff, L. B. (2000). Recovery, persistence, and sequelae in hepatitis C virus infection: a perspective on long-term outcome. Semin Liver Dis 20, 17-35.
-
(2000)
Semin Liver Dis
, vol.20
, pp. 17-35
-
-
Alter, H.J.1
Seeff, L.B.2
-
2
-
-
84860287115
-
Animal models for the study of hepatitis C virus infection and related liver disease
-
Bukh, J. (2012). Animal models for the study of hepatitis C virus infection and related liver disease. Gastroenterology 142, 1279-1287.
-
(2012)
Gastroenterology
, vol.142
, pp. 1279-1287
-
-
Bukh, J.1
-
3
-
-
33644859589
-
A milestone for hepatitis C virus research: A virus generated in cell culture is fully viable in vivo
-
Bukh, J. & Purcell, R. H. (2006). A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo. Proc Natl Acad Sci U S A 103, 3500-3501.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 3500-3501
-
-
Bukh, J.1
Purcell, R.H.2
-
4
-
-
0027450808
-
Hepatitis C virus RNA in southern African blacks with hepatocellular carcinoma
-
Bukh, J., Miller, R. H., Kew, M. C. & Purcell, R. H. (1993). Hepatitis C virus RNA in southern African blacks with hepatocellular carcinoma. Proc Natl Acad Sci U S A 90, 1848-1851.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 1848-1851
-
-
Bukh, J.1
Miller, R.H.2
Kew, M.C.3
Purcell, R.H.4
-
5
-
-
23844523406
-
miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1
-
Chang, J., Nicolas, E., Marks, D., Sander, C., Lerro, A., Buendia, M. A., Xu, C., Mason, W. S., Moloshok, T. & Taylor, J. M. (2004). miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol 1, 106-113.
-
(2004)
RNA Biol
, vol.1
, pp. 106-113
-
-
Chang, J.1
Nicolas, E.2
Marks, D.3
Sander, C.4
Lerro, A.5
Buendia, M.A.6
Xu, C.7
Mason, W.S.8
Moloshok, T.9
Taylor, J.M.10
-
6
-
-
40249106014
-
Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver
-
Elmén, J., Lindow, M., Silahtaroglu, A., Bak, M., Christensen, M., Lind- Thomsen, A., Hedtjärn, M., Hansen, J. B., Hansen, H. F. & Kauppinen, S. (2008). Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res 36, 1153-1162.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 1153-1162
-
-
Elmén, J.1
Lindow, M.2
Silahtaroglu, A.3
Bak, M.4
Christensen, M.5
Lind-Thomsen, A.6
Hedtjärn, M.7
Hansen, J.B.8
Hansen, H.F.9
Kauppinen, S.10
-
7
-
-
0030773306
-
The quasispecies of hepatitis C virus and the host immune response
-
Farci, P., Bukh, J. & Purcell, R. H. (1997). The quasispecies of hepatitis C virus and the host immune response. Springer Semin Immunopathol 19, 5-26.
-
(1997)
Springer Semin Immunopathol
, vol.19
, pp. 5-26
-
-
Farci, P.1
Bukh, J.2
Purcell, R.H.3
-
8
-
-
0032862444
-
Quasispecies in viral persistence and pathogenesis of hepatitis C virus
-
Forns, X., Purcell, R. H. & Bukh, J. (1999). Quasispecies in viral persistence and pathogenesis of hepatitis C virus. Trends Microbiol 7, 402-410.
-
(1999)
Trends Microbiol
, vol.7
, pp. 402-410
-
-
Forns, X.1
Purcell, R.H.2
Bukh, J.3
-
9
-
-
0034747214
-
Sequences in the 5’ nontranslated region of hepatitis C virus required for RNA replication
-
Friebe, P., Lohmann, V., Krieger, N. & Bartenschlager, R. (2001). Sequences in the 5’ nontranslated region of hepatitis C virus required for RNA replication. J Virol 75, 12047-12057.
-
(2001)
J Virol
, vol.75
, pp. 12047-12057
-
-
Friebe, P.1
Lohmann, V.2
Krieger, N.3
Bartenschlager, R.4
-
10
-
-
45749124737
-
Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems
-
Gottwein, J. M. & Bukh, J. (2008). Cutting the gordian knot-development and biological relevance of hepatitis C virus cell culture systems. Adv Virus Res 71, 51-133.
-
(2008)
Adv Virus Res
, vol.71
, pp. 51-133
-
-
Gottwein, J.M.1
Bukh, J.2
-
11
-
-
35648963197
-
Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses
-
Gottwein, J. M., Scheel, T. K., Hoegh, A. M., Lademann, J. B., Eugen- Olsen, J., Lisby, G. & Bukh, J. (2007). Robust hepatitis C genotype 3a cell culture releasing adapted intergenotypic 3a/2a (S52/JFH1) viruses. Gastroenterology 133, 1614-1626.
-
(2007)
Gastroenterology
, vol.133
, pp. 1614-1626
-
-
Gottwein, J.M.1
Scheel, T.K.2
Hoegh, A.M.3
Lademann, J.B.4
Eugen-Olsen, J.5
Lisby, G.6
Bukh, J.7
-
12
-
-
77951437990
-
Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): Genetic analyses and in vivo pathogenesis studies
-
Gottwein, J. M., Scheel, T. K., Callendret, B., Li, Y. P., Eccleston, H. B., Engle, R. E., Govindarajan, S., Satterfield, W., Purcell, R. H. & Bukh, J. (2010). Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studies. J Virol 84, 5277-5293.
-
(2010)
J Virol
, vol.84
, pp. 5277-5293
-
-
Gottwein, J.M.1
Scheel, T.K.2
Callendret, B.3
Li, Y.P.4
Eccleston, H.B.5
Engle, R.E.6
Govindarajan, S.7
Satterfield, W.8
Purcell, R.H.9
Bukh, J.10
-
13
-
-
58049217312
-
microRNA-122 stimulates translation of hepatitis C virus RNA
-
Henke, J. I., Goergen, D., Zheng, J., Song, Y., Schüttler, C. G., Fehr, C., Jünemann, C. & Niepmann, M. (2008). microRNA-122 stimulates translation of hepatitis C virus RNA. EMBO J 27, 3300-3310.
-
(2008)
EMBO J
, vol.27
, pp. 3300-3310
-
-
Henke, J.I.1
Goergen, D.2
Zheng, J.3
Song, Y.4
Schüttler, C.G.5
Fehr, C.6
Jünemann, C.7
Niepmann, M.8
-
14
-
-
0032903304
-
A phylogenetically conserved stem-loop structure at the 5’ border of the internal ribosome entry site of hepatitis C virus is required for capindependent viral translation
-
Honda, M., Beard, M. R., Ping, L. H. & Lemon, S. M. (1999). A phylogenetically conserved stem-loop structure at the 5’ border of the internal ribosome entry site of hepatitis C virus is required for capindependent viral translation. J Virol 73, 1165-1174.
-
(1999)
J Virol
, vol.73
, pp. 1165-1174
-
-
Honda, M.1
Beard, M.R.2
Ping, L.H.3
Lemon, S.M.4
-
15
-
-
84908318087
-
Genetic variation in the non-coding genome: Involvement of micro- RNAs and long non-coding RNAs in disease
-
Hrdlickova, B., de Almeida, R. C., Borek, Z. & Withoff, S. (2014). Genetic variation in the non-coding genome: Involvement of micro- RNAs and long non-coding RNAs in disease. Biochim Biophys Acta 1842, 1910-1922.
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 1910-1922
-
-
Hrdlickova, B.1
de Almeida, R.C.2
Borek, Z.3
Withoff, S.4
-
16
-
-
84923303850
-
Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors
-
Israelow, B., Mullokandov, G., Agudo, J., Sourisseau, M., Bashir, A., Maldonado, A. Y., Dar, A. C., Brown, B. D. & Evans, M. J. (2014). Hepatitis C virus genetics affects miR-122 requirements and response to miR-122 inhibitors. Nat Commun 5, 5408.
-
(2014)
Nat Commun
, vol.5
, pp. 5408
-
-
Israelow, B.1
Mullokandov, G.2
Agudo, J.3
Sourisseau, M.4
Bashir, A.5
Maldonado, A.Y.6
Dar, A.C.7
Brown, B.D.8
Evans, M.J.9
-
17
-
-
77953315225
-
Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122
-
Jangra, R. K., Yi, M. & Lemon, S. M. (2010). Regulation of hepatitis C virus translation and infectious virus production by the microRNA miR-122. J Virol 84, 6615-6625.
-
(2010)
J Virol
, vol.84
, pp. 6615-6625
-
-
Jangra, R.K.1
Yi, M.2
Lemon, S.M.3
-
18
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Janssen, H. L., Reesink, H. W., Lawitz, E. J., Zeuzem, S., Rodriguez- Torres, M., Patel, K., van der Meer, A. J., Patick, A. K., Chen, A. & Hodges, M. R. (2013). Treatment of HCV infection by targeting microRNA. N Engl J Med 368, 1685-1694.
-
(2013)
N Engl J Med
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
van der Meer, A.J.7
Patick, A.K.8
Chen, A.9
Hodges, M.R.10
-
19
-
-
59149102171
-
Regulation of hepatitis C virus by microRNA- 122
-
Jopling, C. L. (2008). Regulation of hepatitis C virus by microRNA- 122. Biochem Soc Trans 36, 1220-1223.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 1220-1223
-
-
Jopling, C.L.1
-
20
-
-
24644483623
-
Modulation of hepatitis C virus RNA abundance by a liverspecific MicroRNA
-
Jopling, C. L., Yi, M., Lancaster, A. M., Lemon, S. M. & Sarnow, P. (2005). Modulation of hepatitis C virus RNA abundance by a liverspecific MicroRNA. Science 309, 1577-1581.
-
(2005)
Science
, vol.309
, pp. 1577-1581
-
-
Jopling, C.L.1
Yi, M.2
Lancaster, A.M.3
Lemon, S.M.4
Sarnow, P.5
-
21
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
Lanford, R. E., Hildebrandt-Eriksen, E. S., Petri, A., Persson, R., Lindow, M., Munk, M. E., Kauppinen, S. & Ørum, H. (2010). Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science 327, 198-201.
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
Kauppinen, S.7
Ørum, H.8
-
22
-
-
79953201904
-
MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR
-
Li, Y. P., Gottwein, J. M., Scheel, T. K., Jensen, T. B. & Bukh, J. (2011a). MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5′ UTR. Proc Natl Acad Sci U S A 108, 4991-4996.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 4991-4996
-
-
Li, Y.P.1
Gottwein, J.M.2
Scheel, T.K.3
Jensen, T.B.4
Bukh, J.5
-
23
-
-
80355146825
-
Non-genotype- specific role of the hepatitis C virus 5′ untranslated region in virus production and in inhibition by interferon
-
Li, Y. P., Ramirez, S., Gottwein, J. M. & Bukh, J. (2011b). Non-genotype- specific role of the hepatitis C virus 5′ untranslated region in virus production and in inhibition by interferon. Virology 421, 222-234.
-
(2011)
Virology
, vol.421
, pp. 222-234
-
-
Li, Y.P.1
Ramirez, S.2
Gottwein, J.M.3
Bukh, J.4
-
24
-
-
84860817692
-
Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains
-
Li, Y. P., Ramirez, S., Gottwein, J. M., Scheel, T. K., Mikkelsen, L., Purcell, R. H. & Bukh, J. (2012a). Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains. Proc Natl Acad Sci U S A 109, E1101-E1110.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E1101-E1110
-
-
Li, Y.P.1
Ramirez, S.2
Gottwein, J.M.3
Scheel, T.K.4
Mikkelsen, L.5
Purcell, R.H.6
Bukh, J.7
-
25
-
-
84870372937
-
Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system
-
Li, Y. P., Ramirez, S., Jensen, S. B., Purcell, R. H., Gottwein, J. M. & Bukh, J. (2012b). Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system. Proc Natl Acad Sci U S A 109, 19757-19762.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 19757-19762
-
-
Li, Y.P.1
Ramirez, S.2
Jensen, S.B.3
Purcell, R.H.4
Gottwein, J.M.5
Bukh, J.6
-
26
-
-
84873149944
-
Competing and noncompeting activities of miR-122 and the 5’ exonuclease Xrn1 in regulation of hepatitis C virus replication
-
Li, Y., Masaki, T., Yamane, D., McGivern, D. R. & Lemon, S. M. (2013). Competing and noncompeting activities of miR-122 and the 5’ exonuclease Xrn1 in regulation of hepatitis C virus replication. Proc Natl Acad Sci U S A 110, 1881-1886.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 1881-1886
-
-
Li, Y.1
Masaki, T.2
Yamane, D.3
McGivern, D.R.4
Lemon, S.M.5
-
27
-
-
84894378216
-
Differential sensitivity of 5’UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors
-
Li, Y. P., Ramirez, S., Humes, D., Jensen, S. B., Gottwein, J. M. & Bukh, J. (2014). Differential sensitivity of 5’UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors. Gastroenterology 146, 812-821.
-
(2014)
Gastroenterology
, vol.146
, pp. 812-821
-
-
Li, Y.P.1
Ramirez, S.2
Humes, D.3
Jensen, S.B.4
Gottwein, J.M.5
Bukh, J.6
-
28
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach, B. D., Evans, M. J., Syder, A. J., Wölk, B., Tellinghuisen, T. L., Liu, C. C., Maruyama, T., Hynes, R. O., Burton, D. R. & Rice, C. M. (2005). Complete replication of hepatitis C virus in cell culture. Science 309, 623-626.
-
(2005)
Science
, vol.309
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
Wölk, B.4
Tellinghuisen, T.L.5
Liu, C.C.6
Maruyama, T.7
Hynes, R.O.8
Burton, D.R.9
Rice, C.M.10
-
29
-
-
84924561760
-
Hepatitis C virus RNA functionally sequesters miR-122
-
Luna, J. M., Scheel, T. K., Danino, T., Shaw, K. S., Mele, A., Fak, J. J., Nishiuchi, E., Takacs, C. N., Catanese, M. T. & Darnell, R. B. (2015). Hepatitis C virus RNA functionally sequesters miR-122. Cell 160, 1099-1110.
-
(2015)
Cell
, vol.160
, pp. 1099-1110
-
-
Luna, J.M.1
Scheel, T.K.2
Danino, T.3
Shaw, K.S.4
Mele, A.5
Fak, J.J.6
Nishiuchi, E.7
Takacs, C.N.8
Catanese, M.T.9
Darnell, R.B.10
-
30
-
-
0037332588
-
Role of the 5’-proximal stem-loop structure of the 5’ untranslated region in replication and translation of hepatitis C virus RNA
-
Luo, G., Xin, S. & Cai, Z. (2003). Role of the 5’-proximal stem-loop structure of the 5’ untranslated region in replication and translation of hepatitis C virus RNA. J Virol 77, 3312-3318.
-
(2003)
J Virol
, vol.77
, pp. 3312-3318
-
-
Luo, G.1
Xin, S.2
Cai, Z.3
-
31
-
-
79952768199
-
Masking the 5’ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex
-
Machlin, E. S., Sarnow, P. & Sagan, S. M. (2011). Masking the 5’ terminal nucleotides of the hepatitis C virus genome by an unconventional microRNA-target RNA complex. Proc Natl Acad Sci U S A 108, 3193-3198.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3193-3198
-
-
Machlin, E.S.1
Sarnow, P.2
Sagan, S.M.3
-
32
-
-
34249024924
-
Replication of hepatitis C virus
-
Moradpour, D., Penin, F. & Rice, C. M. (2007). Replication of hepatitis C virus. Nat Rev Microbiol 5, 453-463.
-
(2007)
Nat Rev Microbiol
, vol.5
, pp. 453-463
-
-
Moradpour, D.1
Penin, F.2
Rice, C.M.3
-
33
-
-
84920116302
-
In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122
-
Ottosen, S., Parsley, T. B., Yang, L., Zeh, K., van Doorn, L. J., van der Veer, E., Raney, A. K., Hodges, M. R. & Patick, A. K. (2015). In vitro antiviral activity and preclinical and clinical resistance profile of miravirsen, a novel anti-hepatitis C virus therapeutic targeting the human factor miR-122. Antimicrob Agents Chemother 59, 599-608.
-
(2015)
Antimicrob Agents Chemother
, vol.59
, pp. 599-608
-
-
Ottosen, S.1
Parsley, T.B.2
Yang, L.3
Zeh, K.4
van Doorn, L.J.5
van der Veer, E.6
Raney, A.K.7
Hodges, M.R.8
Patick, A.K.9
-
34
-
-
33646556662
-
Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras
-
Pietschmann, T., Kaul, A., Koutsoudakis, G., Shavinskaya, A., Kallis, S., Steinmann, E., Abid, K., Negro, F., Dreux, M. & Bartenschlager, R. (2006). Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras. Proc Natl Acad Sci U S A 103, 7408-7413.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7408-7413
-
-
Pietschmann, T.1
Kaul, A.2
Koutsoudakis, G.3
Shavinskaya, A.4
Kallis, S.5
Steinmann, E.6
Abid, K.7
Negro, F.8
Dreux, M.9
Bartenschlager, R.10
-
35
-
-
79952416361
-
Efficient culture adaptation of hepatitis C virus recombinants with genotype-specific core-NS2 by using previously identified mutations
-
Scheel, T. K., Gottwein, J. M., Carlsen, T. H., Li, Y. P., Jensen, T. B., Spengler, U., Weis, N. & Bukh, J. (2011). Efficient culture adaptation of hepatitis C virus recombinants with genotype-specific core-NS2 by using previously identified mutations. J Virol 85, 2891-2906.
-
(2011)
J Virol
, vol.85
, pp. 2891-2906
-
-
Scheel, T.K.1
Gottwein, J.M.2
Carlsen, T.H.3
Li, Y.P.4
Jensen, T.B.5
Spengler, U.6
Weis, N.7
Bukh, J.8
-
36
-
-
84856367312
-
Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex
-
Shimakami, T., Yamane, D., Jangra, R. K., Kempf, B. J., Spaniel, C., Barton, D. J. & Lemon, S. M. (2012). Stabilization of hepatitis C virus RNA by an Ago2-miR-122 complex. Proc Natl Acad Sci U S A 109, 941-946.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 941-946
-
-
Shimakami, T.1
Yamane, D.2
Jangra, R.K.3
Kempf, B.J.4
Spaniel, C.5
Barton, D.J.6
Lemon, S.M.7
-
37
-
-
84894707183
-
Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: Updated criteria and genotype assignment web resource
-
Smith, D. B., Bukh, J., Kuiken, C., Muerhoff, A. S., Rice, C. M., Stapleton, J. T. & Simmonds, P. (2014). Expanded classification of hepatitis C virus into 7 genotypes and 67 subtypes: updated criteria and genotype assignment web resource. Hepatology (Baltimore, Md.) 59, 318-327.
-
(2014)
Hepatology (Baltimore, Md.)
, vol.59
, pp. 318-327
-
-
Smith, D.B.1
Bukh, J.2
Kuiken, C.3
Muerhoff, A.S.4
Rice, C.M.5
Stapleton, J.T.6
Simmonds, P.7
-
38
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
Wakita, T., Pietschmann, T., Kato, T., Date, T., Miyamoto, M., Zhao, Z., Murthy, K., Habermann, A., Kräusslich, H. G. & Liang, T. J. (2005). Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat Med 11, 791-796.
-
(2005)
Nat Med
, vol.11
, pp. 791-796
-
-
Wakita, T.1
Pietschmann, T.2
Kato, T.3
Date, T.4
Miyamoto, M.5
Zhao, Z.6
Murthy, K.7
Habermann, A.8
Kräusslich, H.G.9
Liang, T.J.10
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