Contribution of the arterial system and the heart to blood pressure during normal aging - A simulation study

PLoS ONE

Volumn 11, Issue 6, 2016, Pages

  Maksuti, Elira ^a,b   Westerhof, Nico ^c   Westerhof, Berend E ^d,e   Broomé, Michael ^a,b,f   Stergiopulos, Nikos ^g  

^a ROYAL INSTITUTE OF TECHNOLOGY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d EDWARDS LIFESCIENCES   (United States)

^e ACADEMIC MEDICAL CENTER   (Netherlands)

^f KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^g EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTATION; ADULT; AGE; AGED; AGING; AORTA FLOW; AORTA PRESSURE; ARTERIAL LOAD; ARTERIAL PRESSURE; ARTERIAL STIFFNESS; ARTERY; ARTERY RESISTANCE; ARTICLE; BLOOD PRESSURE; BLOOD VESSEL PARAMETERS; CARDIAC REMODELLING; CARDIOVASCULAR SYSTEM EXAMINATION; DEPRESSED BLOOD PRESSURE; DIASTOLIC BLOOD PRESSURE; ELEVATED BLOOD PRESSURE; HEART; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HUMAN; HYPERTROPHY; MIDDLE AGED; QUANTITATIVE ANALYSIS; SIMULATION; SYSTOLIC BLOOD PRESSURE; VERY ELDERLY; YOUNG ADULT; ALGORITHM; BIOLOGICAL MODEL; COMPUTER SIMULATION; PHYSIOLOGY;

AGING; ALGORITHMS; ARTERIES; BLOOD PRESSURE; COMPUTER SIMULATION; HEART; HUMANS; MODELS, BIOLOGICAL;

EID: 84976491042     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0157493     Document Type: Article

References (41)

1. Franklin SS, Gustin W, Wong ND, Larson MG, Weber MA, Kannel WB, et al. Hemodynamic Patterns of Age-Related Changes in Blood Pressure: The Framingham Heart Study. Circulation. 1997; 96: 308-315. doi: 10.1161/01.CIR.96.1.308 PMID: 9236450
2. Scuteri A, Morrell CH, Orrù M, Strait JB, Tarasov K V, Ferreli LAP, et al. Longitudinal perspective on the conundrum of central arterial stiffness, blood pressure, and aging. Hypertension. 2014; 64: 1219-27. doi: 10.1161/HYPERTENSIONAHA.114.04127 PMID: 25225210
3. O'Rourke MF. Arterial aging: pathophysiological principles. Vasc Med. 2007; 12: 329-341. doi: 10. 1177/1358863X07083392 PMID: 18048471
4. Hickson SS, Butlin M, Graves M, Taviani V, Avolio AP, McEniery CM, et al. The relationship of age with regional aortic stiffness and diameter. JACC Cardiovasc Imaging. 2010; 3: 1247-1255. doi: 10.1016/j.jcmg.2010.09.016 PMID: 21163453
5. Lakatta EG. Changes in cardiovascular function with aging. Eur Heart J. 1990; 11 Suppl C: 22-9. Available: http://www.ncbi.nlm.nih.gov/pubmed/2188839 PMID: 2188839
6. Slotwiner DJ, Devereux RB, Schwartz JE, Pickering TG, de Simone G, Ganau A, et al. Relation of age to left ventricular function in clinically normal adults. Am J Cardiol. 1998; 82: 621-6. Available: http://www.ncbi.nlm.nih.gov/pubmed/9732891 PMID: 9732891
7. Ganau A, Saba PS, Roman MJ, de Simone G, Realdi G, Devereux RB. Ageing induces left ventricular concentric remodelling in normotensive subjects. J Hypertens. 1995; 13: 1818-22. Available: http://www.ncbi.nlm.nih.gov/pubmed/8903659 PMID: 8903659
8. Ioannou C V., Morel DR, Katsamouris AN, Katranitsa S, Startchik I, Kalangos A, et al. Left ventricular hypertrophy induced by reduced aortic compliance. J Vasc Res. 2009; 46: 417-425. doi: 10.1159/000194272 PMID: 19155633
9. Segers P, Stergiopulos N, Westerhof N. Quantification of the contribution of cardiac and arterial remodeling to hypertension. Hypertension. 2000; 36: 760-5. Available: http://www.ncbi.nlm.nih.gov/pubmed/11082140 PMID: 11082140
10. Stergiopulos N, Westerhof BE, Westerhof N. Total arterial inertance as the fourth element of the windkessel model. Am J Physiol. 1999; 276: H81-8. Available: http://www.ncbi.nlm.nih.gov/pubmed/9887020 PMID: 9887020
11. Suga H, Sagawa K, Shoukas AA. Load independence of the instantaneous pressure-volume ratio of the canine left ventricle and effects of epinephrine and heart rate on the ratio. Circ Res. 1973; 32: 314-22. Available: http://www.ncbi.nlm.nih.gov/pubmed/4691336 PMID: 4691336
12. Stergiopulos N, Meister JJ, Westerhof N. Determinants of stroke volume and systolic and diastolic aortic pressure. Am J Physiol. 1996; 270: H2050-9. Available: http://www.ncbi.nlm.nih.gov/pubmed/8764256 PMID: 8764256
13. Mynard JP, Davidson MR, Penny DJ, Smolich JJ. A simple, versatile valve model for use in lumped parameter and one-dimensional cardiovascular models. Int j numer method biomed eng. 2012; 28: 626-641. doi: 10.1002/cnm.1466 PMID: 25364842
14. Senzaki H, Chen CH, Kass DA. Single-beat estimation of end-systolic pressure-volume relation in humans. A new method with the potential for noninvasive application. Circulation. 1996; 94: 2497-506. Available: http://www.ncbi.nlm.nih.gov/pubmed/8921794 PMID: 8921794
15. Cole RT, Lucas CL, Cascio WE, Johnson TA. A LabVIEWmodel incorporating an open-loop arterial impedance and a closed-loop circulatory system. Ann Biomed Eng. 2005; 33: 1555-73. doi: 10.1007/s10439-005-7785-1 PMID: 16341923
16. Boutouyrie P, Vermeersch SJ. Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: Establishing normal and reference values. Eur Heart J. 2010; 31: 2338-2350. doi: 10.1093/eurheartj/ehq165 PMID: 20530030
17. Vardoulis O, Papaioannou TG, Stergiopulos N. On the estimation of total arterial compliance from aortic pulse wave velocity. Ann Biomed Eng. 2012; 40: 2619-26. doi: 10.1007/s10439-012-0600-x PMID: 22648578
18. Wilkinson IB, Franklin SS, Hall IR, Tyrrell S, Cockcroft JR. Pressure Amplification Explains Why Pulse Pressure Is Unrelated to Risk in Young Subjects. Hypertension. 2001; 38: 1461-1466. doi: 10.1161/hy1201.097723 PMID: 11751736
19. Segers P, Rietzschel ER, De Buyzere ML, Vermeersch SJ, De Bacquer D, Van Bortel LM, et al. Noninvasive (input) impedance, pulse wave velocity, and wave reflection in healthy middle-aged men and women. Hypertension. 2007; 49: 1248-55. doi: 10.1161/HYPERTENSIONAHA.106.085480 PMID: 17404183
20. Grossman W, Jones D, McLaurin LP. Wall stress and patterns of hypertrophy in the human left ventricle. J Clin Invest. 1975; 56: 56-64. doi: 10.1172/JCI108079 PMID: 124746
21. Segers P, Stergiopulos N, Schreuder JJ, Westerhof BE, Westerhof N. Left ventricular wall stress normalization in chronic pressure-overloaded heart: a mathematical model study. Am J Physiol Hear Circ Physiol. 2000; 279: H1120-1127. Available: http://ajpheart.physiology.org/content/279/3/H1120.fulltext.pdf+html
22. Saba PS, Roman MJ, Ganau A, Pini R, Jones EC, Pickering TG, et al. Relationship of effective arterial elastance to demographic and arterial characteristics in normotensive and hypertensive adults. J Hypertens. 1995; 13: 971-7. Available: http://www.ncbi.nlm.nih.gov/pubmed/8586832 PMID: 8586832
23. Avolio AP, Van Bortel LM, Boutouyrie P, Cockcroft JR, McEniery CM, Protogerou AD, et al. Role of pulse pressure amplification in arterial hypertension: Experts' opinion and review of the data. Hypertension. 2009. pp. 375-383. doi: 10.1161/HYPERTENSIONAHA.109.134379
24. Willems JL, Roelandt J, De Geest H, Kesteloot H, Joossens J V. The Left Ventricular Ejection Time in Elderly Subjects. Circulation. 1970; 42: 37-42. doi: 10.1161/01.CIR.42.1.37 PMID: 5425593
25. Redfield MM, Jacobsen SJ, Borlaug BA, Rodeheffer RJ, Kass DA. Age- and gender-related ventricularvascular stiffening: a community-based study. Circulation. 2005; 112: 2254-62. doi: 10.1161/CIRCULATIONAHA.105.541078 PMID: 16203909
26. Herbert A, Cruickshank JK, Laurent S, Boutouyrie P. Establishing reference values for central blood pressure and its amplification in a general healthy population and according to cardiovascular risk factors. Eur Heart J. 2014; doi: 10.1093/eurheartj/ehu293
27. Quinn U, Tomlinson L a, Cockcroft JR. Arterial stiffness. JRSM Cardiovasc Dis. 2012; 1: 1-8. doi: 10. 1258/cvd.2012.012024
28. Weber T, Wassertheurer S, Hametner B, Parragh S, Eber B. Noninvasive methods to assess pulse wave velocity: comparison with the invasive gold standard and relationship with organ damage. J Hypertens. 2015; 33: 1023-31. doi: 10.1097/HJH.0000000000000518 PMID: 25668350
29. Kobayashi S, Yano M, Kohno M, Obayashi M, Hisamatsu Y, Ryoke T, et al. Influence of aortic impedance on the development of pressure-overload left ventricular hypertrophy in rats. Circulation. 1996; 94: 3362-8. Available: http://www.ncbi.nlm.nih.gov/pubmed/8989152 PMID: 8989152
30. Mitchell GF, Conlin PR, Dunlap ME, Lacourcière Y, Arnold JMO, Ogilvie RI, et al. Aortic diameter, wall stiffness, and wave reflection in systolic hypertension. Hypertension. 2008; 51: 105-11. doi: 10.1161/HYPERTENSIONAHA.107.099721 PMID: 18071054
31. Chirinos JA, Segers P, Gillebert TC, Gupta AK, De Buyzere ML, De Bacquer D, et al. Arterial properties as determinants of time-varying myocardial stress in humans. Hypertension. 2012; 60: 64-70. doi: 10. 1161/HYPERTENSIONAHA.112.190710 PMID: 22665121
32. Donker DW, Maessen JG, Verheyen F, Ramaekers FC, Spätjens RLHMG, Kuijpers H, et al. Impact of acute and enduring volume overload on mechanotransduction and cytoskeletal integrity of canine left ventricular myocardium. Am J Physiol Heart Circ Physiol. 2007; 292: H2324-H2332. doi: 10.1152/ajpheart.00392.2006 PMID: 17220194
33. Dhalla NS, Rangi S, Babick AP, Zieroth S, Elimban V. Cardiac remodeling and subcellular defects in heart failure due to myocardial infarction and aging. Heart Fail Rev. 2012; 17: 671-81. doi: 10.1007/s10741-011-9278-7 PMID: 21850540
34. Biernacka A, Frangogiannis NG. Aging and Cardiac Fibrosis. Aging Dis. 2011; 2: 158-173. Available: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3758275&tool=pmcentrez&rendertype= abstract PMID: 21837283
35. Borlaug BA, Redfield MM, Melenovsky V, Kane GC, Karon BL, Jacobsen SJ, et al. Longitudinal changes in left ventricular stiffness: a community-based study. Circ Heart Fail. 2013; 6: 944-52. doi: 10.1161/CIRCHEARTFAILURE.113.000383 PMID: 23811963
36. Kostis JB, Moreyra AE, Amendo MT, Di Pietro J, Cosgrove N, Kuo PT. The effect of age on heart rate in subjects free of heart disease. Studies by ambulatory electrocardiography and maximal exercise stress test. Circulation. 1982; 65: 141-5. Available: http://www.ncbi.nlm.nih.gov/pubmed/7198013 PMID: 7198013
37. Carlsson M, Andersson R, Bloch K, Steding-Ehrenborg K, Mosén H, Stahlberg F, et al. Cardiac output and cardiac index measured with cardiovascular magnetic resonance in healthy subjects, elite athletes and patients with congestive heart failure. Journal of Cardiovascular Magnetic Resonance. 2012. p. 51. doi: 10.1186/1532-429X-14-51 PMID: 22839436
38. Cain PA, Ahl R, Hedstrom E, Ugander M, Allansdotter-Johnsson A, Friberg P, et al. Age and gender specific normal values of left ventricular mass, volume and function for gradient echo magnetic resonance imaging: a cross sectional study. BMC Med Imaging. 2009; 9: 2. doi: 10.1186/1471-2342-9-2 PMID: 19159437
39. Claessens TE, Rietzschel ER, De Buyzere ML, De Bacquer D, De Backer G, Gillebert TC, et al. Noninvasive assessment of left ventricular and myocardial contractility in middle-aged men and women: disparate evolution above the age of 50? Am J Physiol Heart Circ Physiol. 2007; 292: H856-65. Available: http://www.ncbi.nlm.nih.gov/pubmed/17287452 PMID: 17287452
40. Berge HM, Isern CB, Berge E. Blood pressure and hypertension in athletes: a systematic review. Br J Sports Med. 2015; 49(11): 716-723. doi: 10.1136/bjsports-2014-093976 PMID: 25631543
41. Vaitkevicius P V, Fleg JL, Engel JH, O'Connor FC, Wright JG, Lakatta LE, et al. Effects of age and aerobic capacity on arterial stiffness in healthy adults. Circulation. 1993; 88: 1456-62. Available: http://www.ncbi.nlm.nih.gov/pubmed/8403292 PMID: 8403292