Kaempferol loaded lecithin/chitosan nanoparticles: preparation, characterization, and their potential applications as a sustainable antifungal agent

Artificial Cells, Nanomedicine and Biotechnology

Volumn 45, Issue 5, 2017, Pages 907-916

  Ilk, Sedef ^a   Saglam, Necdet ^b   Özgen, Mustafa ^a  

^a NIGDE UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Antifungal agent; encapsulation; kaempferol; nanoparticle engineering system; plant pathogens; safe natural

Indexed keywords

AGRICULTURE; ANTIOXIDANTS; BIOCHEMISTRY; ENCAPSULATION; FLAVONOIDS; FUNGI; FUNGICIDES; LECITHIN; NANOPARTICLES; SELF ASSEMBLY;

CHITOSAN NANOPARTICLES; ELECTROSTATIC SELF ASSEMBLY; ENGINEERING SYSTEMS; KAEMPFEROL; PHYSICO-CHEMICAL STABILITY; PHYSICOCHEMICAL PROPERTY; PLANT PATHOGEN; SAFE NATURAL;

ANTIFUNGAL AGENTS;

CHITOSAN NANOPARTICLE; KAEMPFEROL; PHOSPHATIDYLCHOLINE; ANTIFUNGAL AGENT; ANTIOXIDANT; CHITOSAN; DRUG CARRIER; KAEMPFEROL DERIVATIVE; NANOPARTICLE;

ANTIFUNGAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; COMPARATIVE STUDY; DRUG BIOAVAILABILITY; DRUG DETERMINATION; DRUG POTENCY; DRUG SOLUBILITY; DRUG STABILITY; DRUG SYNTHESIS; FUSARIUM OXYSPORUM; IN VITRO STUDY; NANOENCAPSULATION; PHYSICAL CHEMISTRY; SURFACE PROPERTY; SUSTAINED DRUG RELEASE; ZETA POTENTIAL; CHEMISTRY; DRUG EFFECTS; FUSARIUM;

ANTIFUNGAL AGENTS; ANTIOXIDANTS; CHITOSAN; DRUG CARRIERS; FUSARIUM; KAEMPFEROLS; LECITHINS; NANOPARTICLES;

EID: 84976317513     PISSN: 21691401     EISSN: 2169141X     Source Type: Journal    
DOI: 10.1080/21691401.2016.1192040     Document Type: Article

References (30)

1. Barbieri S, Sonvico F, Como C, Colombo G, Zani F, Buttini F, et al. 2013. Lecithin/chitosan controlled release nanopreparations of tamoxifen citrate:loading, enzyme-trigger release and cell uptake. J Control Release. 167:276–283.
2. Chadha R, Bhandari S, Kataria D, Gupta S, Singh Jain D., 2012. Exploring the potential of lecithin/chitosan nanoparticles in enhancement of antihypertensive efficacy of hydrochlorothiazide. J Microencapsul. 29:805–812.
3. Göktürk I, Karakoç V, Onur MA, Denizli A., 2013. Characterization and cellular interaction of fluorescent-labeled PHEMA nanoparticles. Artif Cells Nanomed Biotechnol. 41:78–84.
4. Guerra-Sanchez MG, Vega-Pérez J, Velázquez-del Valle MG, Hernández-Lauzardo AN., 2009. Antifungal activity and release of compounds on Rhizopus stolonifer (Ehrenb.:Fr.) Vuill. by effect of chitosan with different molecular weights. Pestic Biochem Phys. 93:18–22.
5. Guo ZY, Chen R, Xing R, Liu S, Yu H, Wang P, Li C, Li P., 2006. Novel derivatives of chitosan and their antifungal activities in vitro. Carbohydr Res. 341:351–354.
6. Gupta A, Kaura CD, Saraf S, Saraf S., 2016. Formulation, characterization, and evaluation of ligand-conjugated biodegradable quercetin nanoparticles for active targeting. Artif Cells Nanomed Biotechnol. 44:960–970.
7. Hafner A, Lovric J, Voinovich D, Filipovic-Gr J., 2009. Melatonin-loaded lecithin/chitosan nanoparticles:physicochemical characterisation and permeability through Caco-2 cell monolayers. Int J Pharm. 381:205–213.
8. Hahn M., 2014. The rising threat of fungicide resistance in plant pathogenic fungi:Botrytis as a case study. J Chem Res. 7:133–141.
9. Ing LY, Zin NM, Sarwar A, Katas H., 2012. Antifungal activity of chitosan nanoparticles and correlation with their physical properties. Int J Biomater. 2012:1–9.
10. Kopparapu NK, Liu ZQ, Yan QJ, Jiang ZQ, Zhang SP., 2011. A novel thermostable chitinase (PJC) from pomegranate (Punica granatum) juice. Food Chem. 127:1569–1575.
11. Luo H, Jiang B, Li B, Li Z, Jiang B, Chen YC., 2012. Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability. Int J Nanomedicine. 7:3951–3959.
12. Mora-Huertas CE, Fessi H, Elaissari A., 2010. Polymer-based nanocapsules for drug delivery. Int J Pharm. 385:113–142.
13. Özcan İ, Azizoğlu E, Şenyiğit T, Özyazıcı M, Özer Ö., 2013. Enhanced dermal delivery of diflucortolone valerate using lecithin/chitosan nanoparticles:in-vitro and in-vivo evaluations. Int J Nanomedicine. 8:461–475.
14. Patila AG, Jobanputraa AH., 2015. Rutin-chitosan nanoparticles:fabrication, characterization and application in dental disorders. Polym Plast Technol. 54:202–208.
15. Pool H, Quintanar D, Figueroa JD, Mano CM, Bechara JEH, Godinez LA, Mendoza S., 2012. Antioxidant effects of quercetin and catechin encapsulated into PLGA nanoparticles. J Nanomater. 2012:1–12.
16. Satpath G, Tyagi YK, Gupta RKA., 2011. novel optimized and validated method for analysis of multi residues of pesticides in fruits and vegetables using microwave-reaction system (MRS)-dispersive solid phase extraction(d-SPE)-retention time locked (RTL)-gas chromatography–mass spectrometry with deconvolution reporting software (DRS). Food Chem. 127:1300–1308.
17. Şenyiğit T, Sonvico F, Barbieri S, Özer O, Santi P, Colombo P., 2010. Lecithin/chitosan nanoparticles of clobetasol-17-propionate capable of accumulation in pig skin. J Control Release. 142:368–373.
18. Shahi SK, Shukla AC, Bajaj AK, Midgely G, Dikshit A., 1999. Board spectrum antimycotic drug for the control of fungal infections in human beings. Curr Sci. 74:836–839.
19. Saharan V, Mehrotra A, Khatik R, Rawal P, Sharma SS, Pal A., 2013. Synthesis of chitosan based nanoparticles and their in vitro evaluation against phytopathogenic fungi. Int J Biol Macromol. 62:677–683.
20. Saharan V, Sharma G, Yadav M, Choudhary MK, Sharma SS, Pal A, Raliya R, Biswas P., 2015. Synthesis and in vitro antifungal efficacy of Cu-chitosan nanoparticles against pathogenic fungi of tomato. Int J Biol Macromol. 75:346–353.
21. Sharma D, Rajput J, Kaith BS, Kaur M, Sharma S., 2010. Synthesis of ZnO nanoparticles and study of their antibacterial and antifungal properties. Thin Solid Films. 519:1224–1229.
22. Sonvico F, Cagnani A, Rossi A, Motta S, Di Bari MT, Cavatorta F, et al. 2006. Formation of self-organized nanoparticles by lecithin/chitosan ionic interaction. Int J Pharm. 324:67–73.
23. Souza M P, Vaz AFM, Correia MTS, Cerqueira MA, Vicente AA, Carneiro-da-Cunha MG., 2014. Quercetin-loaded lecithin/chitosan nanoparticles for functional food applications. Food Bioprocess Tech. 7:1149–1159.
24. Tan Q, Liu W, Guo C, Zhai G., 2011. Preparation and evaluation of quercetin-loaded lecithin–chitosan nanoparticles for topical delivery. Int J Nanomedicine. 6:1621–1630.
25. Tzeng CW, Yen FL, Wu TH, Ko HH, Lee CW, Tzeng WS, Lin CC., 2011. Enhancement of dissolution and antioxidant activity of kaempferol using a nanoparticle engineering process. J Agric Food Chem. 59:5073–5080.
26. Wang SY, Chen C, Wang CY., 2009. The influence of light and maturity on fruit quality and flavonoid content of red raspberries. Food Chem. 112:676–684.
27. Wiarachai O, Thongchul N, Kiatkamjornwong S, Hoven VP., 2012. Surface-quaternized chitosan particles as an alternative and effective organic antibacterial material. Colloids Surf B Biointerfaces. 92:121–129.
28. Yadav KS, Sawant KK., 2010. Modified nanoprecipitation method for preparation of cytarabine-loaded PLGA nanoparticles. AAPS PharmSciTech. 11:1456–1465.
29. Zhang Y, Yang Y, Tang K, Hu X, Zou G., 2008. Physicochemical characterization and antioxidant activity of quercetin-loaded chitosan nanoparticles. J Appl Polym Sci. 107:891–897.
30. Zhong Z, Chen R, Xing R, Chen X, Liu S, Guo Z, et al. 2007. Synthesis and antifungal properties of sulfanilamide derivatives of chitosan. Carbohydr Res. 342:2390–2395.