Biochanin A protects lipopolysaccharide/D-galactosamine-induced acute liver injury in mice by activating the Nrf2 pathway and inhibiting NLRP3 inflammasome activation

International Immunopharmacology

Volumn 38, Issue , 2016, Pages 324-331

  Liu, Xingkai ^a   Wang, Tuo ^a   Liu, Xueshibojie ^a   Cai, Lu ^b   Qi, Jun ^a   Zhang, Ping ^a   Li, Yan ^b  

^a JILIN UNIVERSITY   (China)

^b University of Louisville School of Medicine   (United States)

Author keywords

Biochanin A; LPS; NLRP3; Nrf2; TXNIP

Indexed keywords

ADAPTOR PROTEIN; ALANINE AMINOTRANSFERASE; ASC PROTEIN; ASPARTATE AMINOTRANSFERASE; BIOCHANIN A; CATALASE; CRYOPYRIN; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GALACTOSAMINE; GLUTATHIONE PEROXIDASE; HEME OXYGENASE 1; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MALONALDEHYDE; SUPEROXIDE DISMUTASE; THIOREDOXIN INTERACTING PROTEIN; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; CARRIER PROTEIN; GENISTEIN; HMOX1 PROTEIN, MOUSE; LIPOPOLYSACCHARIDE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE; NLRP3 PROTEIN, MOUSE; THIOREDOXIN; TUMOR NECROSIS FACTOR; TXNIP PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; EXPERIMENTAL LIVER INJURY; HISTOPATHOLOGY; LIVER; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; UPREGULATION; ANIMAL; BAGG ALBINO MOUSE; CHEMICAL AND DRUG INDUCED LIVER INJURY; DRUG EFFECTS; GENETICS; IMMUNOLOGY; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CARRIER PROTEINS; CHEMICAL AND DRUG INDUCED LIVER INJURY; GALACTOSAMINE; GENISTEIN; HEME OXYGENASE-1; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; SIGNAL TRANSDUCTION; THIOREDOXINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84975853510     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2016.06.009     Document Type: Article

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