Limb ischemic perconditioning attenuates blood-brain barrier disruption by inhibiting activity of MMP-9 and occludin degradation after focal cerebral ischemia

Aging and Disease

Volumn 6, Issue 6, 2015, Pages 406-417

  Ren, Changhong ^a,b,e,f   Li, Ning ^a,e   Wang, Brian ^b   Yang, Yong ^c   Gao, Jinhuan ^a   Li, Sijie ^a,e   Ding, Yuchuan ^d   Jin, Kunlin ^a,b   Ji, Xunming ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF NORTH TEXAS   (United States)

^c BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e BEIJING INSTITUTE FOR BRAIN DISORDERS   (China)

^f Beijing Key Laboratory of Hypoxic Conditioning Translational Medicine   (China)

Author keywords

Blood brain barrier; Ischemic stroke; Matrix metalloproteinases; Remote ischemic perconditioning; Tight junction

Indexed keywords

CLAUDIN 5; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; OCCLUDIN; PROTEIN ZO1;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN EDEMA; BRAIN ISCHEMIA; CHEMOLUMINESCENCE; COGNITIVE FUNCTION TEST; CONTROLLED STUDY; CORONARY REPERFUSION; DOWN REGULATION; ENZYME ACTIVITY; IMMUNOFLUORESCENCE TEST; ISCHEMIC PERCONDITIONING; LIMB ISCHEMIA; MALE; MEDICAL PROCEDURES; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; ZYMOGRAPHY;

EID: 84975780363     PISSN: None     EISSN: 21525250     Source Type: Journal    
DOI: 10.14336/AD.2015.0812     Document Type: Article

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