Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity

Cell

Volumn 163, Issue 3, 2015, Pages 746-758

  Swanson, Michael D ^a,l   Boudreaux, Daniel M ^a,b   Salmon, Loïc ^b   Chugh, Jeetender ^b   Winter, Harry C ^c   Meagher, Jennifer L ^b   André, Sabine ^d   Murphy, Paul V ^e   Oscarson, Stefan ^f   Roy, René ^g   King, Steven ^a   Kaplan, Mark H ^a   Goldstein, Irwin J ^c   Tarbet, E Bart ^h   Hurst, Brett L ^h   Smee, Donald F ^h   De La Fuente, Cynthia ⁱ   Hoffmann, Hans Heinrich ⁱ   Xue, Yi ^j   Rice, Charles M ⁱ   Schols, Dominique ^k   Garcia, J Victor ^l   Stuckey, Jeanne A ^b   Gabius, Hans Joachim ^d   Al Hashimi, Hashim M ^b,j   Markovitz, David M ^a   more..

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MUNICH   (Germany)

^e NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^f UNIVERSITY COLLEGE DUBLIN   (Ireland)

^g UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^h UTAH STATE UNIVERSITY   (United States)

ⁱ ROCKEFELLER UNIVERSITY   (United States)

^j DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^l UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; ASPARTIC ACID; COMPLEMENTARY DNA; GLUTAMIC ACID; GLUTAMINE; HISTIDINE; LEUCINE; LYSINE; MANNOSE; PHENYLALANINE; PLANT LECTIN; THREONINE; TRYPTOPHAN; TYROSINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; MITOGENIC AGENT;

AMINO ACID SUBSTITUTION; ANTIVIRAL ACTIVITY; ARTICLE; BANANA; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG POTENCY; ESCHERICHIA COLI; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; INFLUENZA VIRUS; MITOGENESIS; MITOGENICITY; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; CARBOHYDRATE ANALYSIS; CHEMISTRY; GENETIC ENGINEERING; GENETICS; MOLECULAR DYNAMICS; MOLECULAR MODEL; MUSA;

ANTI-HIV AGENTS; CARBOHYDRATE SEQUENCE; GENETIC ENGINEERING; MITOGENS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MUSA; PLANT LECTINS;

EID: 84975687495     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2015.09.056     Document Type: Article

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