Unraveling functional significance of natural variations of a human galectin by glycodendrimersomes with programmable glycan surface

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 18, 2015, Pages 5585-5590

  Zhang, Shaodong ^a   Moussodia, Ralph Olivier ^a   Vértesy, Sabine ^b   André, Sabine ^b   Klein, Michael L ^c   Gabius, Hans Joachim ^b   Percec, Virgil ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c Temple University   (United States)

Author keywords

Adhesion; Agglutination; Glycobiology; Membrane mimic; Self assembly

Indexed keywords

AGGLUTININ; DENDRIMER; GALECTIN; GLYCAN; GLYCODENDRIMERSOME; LECTIN; LIGAND; MUTANT PROTEIN; PHENYLALANINE; TYROSINE; UNCLASSIFIED DRUG; LGALS8 PROTEIN, HUMAN; POLYSACCHARIDE; PROTEIN BINDING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC VARIABILITY; GLYCOBIOLOGY; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; TRANS ISOMER; ALTERNATIVE RNA SPLICING; AUTOIMMUNE DISEASE; CELL COMMUNICATION; CELL MEMBRANE; CHEMISTRY; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN CONFORMATION; SINGLE NUCLEOTIDE POLYMORPHISM;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; AUTOIMMUNE DISEASES; CELL COMMUNICATION; CELL MEMBRANE; GALECTINS; HUMANS; LECTINS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR SEQUENCE DATA; MUTATION; POLYMORPHISM, SINGLE NUCLEOTIDE; POLYSACCHARIDES; PROTEIN BINDING; PROTEIN CONFORMATION;

EID: 84928975425     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1506220112     Document Type: Article

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