Lisdexamfetamine reduces the compulsive and perseverative behaviour of binge-eating rats in a novel food reward/punished responding conflict model

Journal of Psychopharmacology

Volumn 30, Issue 7, 2016, Pages 662-675

  Heal, David J ^a   Goddard, Simon ^a   Brammer, Richard J ^a   Hutson, Peter H ^b   Vickers, Steven P ^a  

^a RenaSci Ltd   (United Kingdom)

^b SHIRE   (United States)

Author keywords

binge eating; compulsive; conflict model; Lisdexamfetamine; perseverative

Indexed keywords

LISDEXAMFETAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BEHAVIOR ASSESSMENT; BINGE EATING DISORDER; COMPULSION; CONTROLLED STUDY; DRUG APPROVAL; DRUG EFFECT; DRUG RESPONSE; FEMALE; NONHUMAN; PERSEVERATIVE BEHAVIOR; PRIORITY JOURNAL; PUNISHMENT; RAT; REWARD; STIMULUS RESPONSE; TASK PERFORMANCE; UNITED STATES; ANIMAL; BULIMIA; DRUG EFFECTS; FEEDING BEHAVIOR; INSTRUMENTAL CONDITIONING; WISTAR RAT;

ANIMALS; BINGE-EATING DISORDER; BULIMIA; COMPULSIVE BEHAVIOR; CONDITIONING, OPERANT; FEEDING BEHAVIOR; FEMALE; LISDEXAMFETAMINE DIMESYLATE; RATS; RATS, WISTAR; REWARD;

EID: 84975514594     PISSN: 02698811     EISSN: 14617285     Source Type: Journal    
DOI: 10.1177/0269881116647506     Document Type: Article

References (52)

1. American Psychiatric Association (2013) Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. American Psychiatric Association, Arlington, VA. Available at: http://www.dsm.psychiatryonline.org (. accessed 1 June 2013).
2. Biederman J, Ball SW, Monuteaux MC, et al. (2007) Are girls with ADHD at risk for eating disorders? Results from a controlled, five-year prospective study. J Dev Behav Pediatr 28: 302-307.
3. Bolea-Alamañac B, Nutt DJ, Adamou M, et al. (2014) Evidence-based guidelines for the pharmacological management of attention deficit hyperactivity disorder: update on recommendations from the British Association for Psychopharmacology. J Psychopharmacol 28: 179-203.
4. Citrome L, (2015) Lisdexamfetamine for binge eating disorder in adults: a systematic review of the efficacy and safety profile for this newly approved indication-what is the number needed to treat, number needed to harm and likelihood to be helped or harmed? Int J Clin Pract 69: 410-421.
5. Claudino AM, de Oliveira IR, Appolinario JC, et al. (2007). Double-blind, randomized, placebo-controlled trial of topiramate plus cognitive-behavior therapy in binge-eating disorder. J Clin Psychiatry 68: 1324-1332.
6. Colles SL, Dixon JB, O'Brien PE, (2008) Loss of control is central to psychological disturbance associated with binge eating disorder. Obesity 16: 608-614.
7. Cortese S, Bernardina BD, Mouren MC, (2007). Attention-deficit/hyperactivity disorder (ADHD) and binge eating. Nutr Rev 65: 404-411.
8. Corwin RL, (2004) Binge-type eating induced by limited access in rats does not require energy restriction on the previous day. Appetite 42: 139-142.
9. de Jong JW, Meijboom KE, Vanderschuren LJMJ, et al. (2013) Low control over palatable food intake in rats is associated with habitual behavior and relapse vulnerability: individual differences. PLoS ONE 8: e74645.
10. de Zwaan M, Mitchell JE, Seim HC, et al. (1994) Eating related and general psychopathology in obese females with binge eating disorder. Int J Eat Disord 15: 43-52.
11. Dingemans AE, Bruna MJ, van Furth EF, (2002) Binge eating disorder: a review. Int J Obes 26: 299-307.
12. Docet MF, Larrañaga A, Pérez Méndez LF, et al. (2012) Attention deficit hyperactivity disorder increases the risk of having abnormal eating behaviours in obese adults. Eat Weight Disord 17: e132-e136.
13. Fairburn CG, Cooper Z, Doll HA, et al. (2000). The natural course of bulimia nervosa and binge eating disorder in young women. Arch Gen Psychiatry 57: 659-665.
14. Fernández-Aranda F, Agüera Z, Castro R, et al. (2013) ADHD symptomatology in eating disorders: a secondary psychopathological measure of severity? BMC Psychiatry 13: 166.
15. Galanti K, Gluck ME, Geliebter A, (2007) Test meal intake in obese binge eaters in relation to impulsivity and compulsivity. Int J Eat Disord 40: 727-732.
16. Gearhardt AN, White MA, Potenza MN, (2011) Binge eating disorder and food addiction. Curr Drug Abuse Rev 4: 201-207.
17. Giuliano C, Robbins TW, Nathan PJ, et al. (2012) Inhibition of opioid transmission at the μ-opioid receptor prevents both food seeking and binge-like eating. Neuropsychopharmacology 37: 2643-2652.
18. Goldschmidt AB, Le Grange D, Powers P, et al. (2011) Eating disorder symptomatology in normal-weight vs. obese individuals with binge-eating disorder. Obesity 19: 1515-1518.
19. Guerdijkova AI, McElroy SL, Wedge JA, et al. (2009) Lamotrigine in the treatment of binge-eating disorder with obesity: a randomized, placebo-controlled monotherapy trial. Int Clin Psychopharmacol 24: 150-158.
20. Heal DJ, Smith SL, Gosden J, et al. (2013a) Amphetamine, past and present-a pharmacological and clinical perspective. J Psychopharmacol 27: 479-496.
21. Heal DJ, Vickers SP, Hackett D, et al. (2013b) Metabolic effects of lisdexamfetamine in a rat model of human obesity with insulin resistance. Eur Neuropsychoparmacol 23: S207.
22. Hoek HW, van Hoeken D, (2003). Review of the prevalence and incidence of eating disorders. Int J Eat Disord 34: 383-396.
23. Hudson JI, Hiripi E, Pope HG Jr, et al. (2007) The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication. Biol Psychiatry 61: 348-358.
24. Hutson PH, Pennick M, Secker R, (2014) Preclinical pharmacokinetics, pharmacology and toxicology of lisdexamfetamine: a novel d -amphetamine pro-drug. Neuropharmacology 87: 41-50.
25. Hutson PH, Vickers SP, Goddard S, et al. (2015) Preclinical evidence to demonstrate that lisdexamfetamine prevents impulsivity in binge-eating. In: Proceedings of the 54th American College of Neuropsychopharmacology Meeting, Hollywood, FL, 6-10 December, Abstract M46.
26. Jääskeläinen A, Nevaapera N, Remes J, et al. (2014) Stress-related eating, obesity and associated behavioral traits in adolescents: a prospective population-based cohort study. BMC Public Health 14: 321.
27. Masheb RM, Grilo CM, Brondolo E, (1999) Shame and its psychopathologic correlates in two women's health problems: binge eating disorder and vulvodynia. Eat Weight Disord 4: 187-193.
28. Mattingly G, Weisler R, Dirks B, et al. (2012) Attention deficit hyperactivity disorder subtypes and symptom response in adults treated with lisdexamfetamine dimesylate. Innov Clin Neurosci 9: 22-30.
29. McElroy SL, Guerdjikova AI, Blom TJ, et al. (2013) A placebo-controlled pilot study of the novel opioid receptor antagonist ALKS-33 in binge eating disorder. Int J Eat Disord 46: 239-245.
30. McElroy SL, Hudson JI, Mitchell JE, et al. (2015) Efficacy and safety of lisdexamfetamine dimesylate for treatment of adults with moderate to severe binge eating disorder: a randomized, double-blind, placebo-controlled trial. JAMA 72: 235-246.
31. McElroy SL, Hudson J, Ferreira-Cornwell MC, et al. (2016a) Lisdexamfetamine dimesylate for adults with moderate to severe binge eatingdisorder: results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology 41: 1251-1260.
32. McElroy SL, Mitchell JE, Wilfley D, et al. (2016b) Lisdexamfetaminedimesylate effects on binge eating behaviour and obsessive-compulsive and impulsive features in adults with binge eating disorder. Eur Eat Disord Rev. 24: 223-231.
33. Najib J, (2012) Lisdexamfetamine in the treatment of adolescents and children with attention-deficit/hyperactivity disorder. Adolsc Health Med Ther 3: 51-66.
34. Oswald KD, Murdaugh DL, King VL, et al. (2011) Motivation for palatable food despite consequences in an animal model of binge-eating. Int J Eat Disord 44: 203-211.
35. Qian J, Hu Q, Wan Y, et al. (2013) Prevalence of eating disorders in the general population: a systematic review. Shanghai Arch Psychiatry 25: 212-223.
36. Rigaud D, Jiang T, Pennacchio H, et al. (2014) Triggers of bulimia and compulsion attacks: validation of the "START" questionnaire. Encephale 40: 323-329 (in French).
37. Rossetti C, Spena G, Halfon O, et al. (2013) Evidence for a compulsive-like behavior in rats exposed to alternate access to highly preferred palatable food. Addict Biol 19: 975-985.
38. Rowley HL, Kulkarni RS, Gosden J, et al. (2012) Lisdexamfetamine and immediate release d- amphetamine-differences in pharmacokinetic/pharmacodynamic relationships revealed by striatal microdialysis in freely-moving rats with simultaneous determination of plasma drug concentrations and locomotor activity. Neuropharmacology 63: 1064-1074.
39. Rowley HL, Kulkarni RS, Gosden J, et al. (2014) Differences in the neurochemical and behavioural profiles of lisdexamfetamine, methylphenidate and modafinil revealed by simultaneous dual-probe microdialysis and locomotor activity measurements in freely-moving rats. J Psychopharmacol 28: 254-269.
40. Schag K, Schonleber J, Teufel M, et al. (2013) Food-related impulsivity in obesity and binge eating disorder-a systematic review. Obes Rev 14: 477-495.
41. Sotty F, Damgaard T, Montezinho LP, et al. (2009) Antipsychotic-like effect of retigabine [N-(2-amino-4-(fluorobenzylamino)-phenyl) carbamic acid ester], a KCNQ potassium channel opener, via modulation of mesolimbic dopaminergic neurotransmission. J Pharm Exp Ther 328: 951-962.
42. Svaldi J, Naumann E, Trentowska M, et al. (2014) General and food-specific inhibitory deficits in binge eating disorder. Int J Eat Disord 47: 534-542.
43. US Food and Drug Administration (2015) News release: FDA expands uses of Vyvanse to treat binge-eating disorder. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm432543.htm.
44. Vannucci A, Theim KR, Kass AE, et al. (2013) What constitutes clinically significant binge eating? Association between binge features and clinical validators in college-age women. Int J Eat Disord 46: 226-232.
45. Vickers SP, Hackett D, Murray F, et al. (2015) Effects of lisdexamfetamine in a rat model of binge-eating. J Psychopharmacol 29: 1290-1307.
46. Weisler RH, Adler LA, Kollins SH, et al. (2014) Analysis of individual items on the attention-deficit/hyperactivity disorder symptom rating scale in children and adults: the effects of age and sex in pivotal trials of lisdexamfetamine dimesylate. Neuropsychiatr Dis Treat 10: 1-12.
47. White MA, Grilo CM, (2013) Bupropion for overweight women with binge eating disorder: randomized double-blind placebo-controlled trial. J Clin Psychiatry 74: 400-406.
48. Wonderlich SA, Gordon KH, Mitchell JE, et al. (2009) The validity and clinical utility of binge-eating disorder. Int J Eat Disord 42: 687-705.
49. Wong KJ, Wojnicki FHW, Corwin RLW, (2009) Baclofen, raclopride, and naltrexone differentially affect intake of fat/sucrose mixtures under limited access conditions. Pharmacol Biochem Behav 92: 528-536.
50. Wu M, Giel KE, Skunde M, et al. (2013) Inhibitory control and decision making under risk in bulimia nervosa and binge-eating disorder. Int J Eat Disord 46: 721-728.
51. Yanovski S, (2003) Sugar and fat: cravings and aversions. J Nutr 133: 835S-837S.
52. Ziauddeen H, Chamberlain SR, Nathan PJ, et al. (2013) Effects of the μ-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects. Mol Psychiatry 18: 1287-1293.