Preclinical pharmacokinetics, pharmacology and toxicology of lisdexamfetamine: A novel d-amphetamine pro-drug

Neuropharmacology

Volumn 87, Issue , 2014, Pages 41-50

  Hutson, Peter H ^a   Pennick, Michael ^b   Secker, Roger ^b  

^a Shire Pharmaceuticals   (United States)

^b Shire Pharmaceuticals   (United Kingdom)

Author keywords

Attention deficit hyperactivity disorder; d Amphetamine; Lisdexamfetamine dimesylate; Pharmacokinetics; Pharmacology; Toxicology

Indexed keywords

DEXAMPHETAMINE; LISDEXAMFETAMINE; METHYLPHENIDATE; CENTRAL STIMULANT AGENT; PRODRUG;

AREA UNDER THE CURVE; ATTENTION DEFICIT DISORDER; DRUG ABSORPTION; DRUG ACTIVITY; DRUG ELIMINATION; DRUG METABOLISM; DRUG POTENCY; DRUG STRUCTURE; DRUG TISSUE LEVEL; GENOTOXICITY; HUMAN; HYDROLYSIS; IMPULSIVENESS; ISOTOPE LABELING; LIPOPHILICITY; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PHARMACODYNAMICS; PHYSICAL CHEMISTRY; PREFRONTAL CORTEX; REVIEW; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; ANIMAL; BRAIN; DRUG EFFECTS; METABOLISM;

ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; DEXTROAMPHETAMINE; HUMANS; PRODRUGS;

EID: 84908542768     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2014.02.014     Document Type: Review

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