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Volumn 7, Issue 14, 2016, Pages 17415-17430

Up-regulation of serotonin receptor 2B mRNA and protein in the peri-infarcted area of aged rats and stroke patients

Author keywords

Aging; Gerotarget; Neurogenesis; Post stroke depression; Serotonin receptor type B; Stroke

Indexed keywords

FLUOXETINE; HTR2B PROTEIN; SEROTONIN 2 RECEPTOR; SEROTONIN RECEPTOR 2A; SEROTONIN RECEPTOR 2B; UNCLASSIFIED DRUG; MESSENGER RNA; SEROTONIN 2B RECEPTOR; SEROTONIN UPTAKE INHIBITOR;

EID: 84975481412     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8277     Document Type: Article
Times cited : (26)

References (73)
  • 3
    • 79960733740 scopus 로고    scopus 로고
    • Prestroke proteomic changes in cerebral microvessels in stroke-prone, transgenic [hCETP]-Hyperlipidemic, Dahl salt-sensitive hypertensive rats
    • Bergerat A, Decano J, Wu CJ, Choi H, Nesvizhskii AI, Moran AM, Ruiz-Opazo N, Steffen M, and Herrera VL. Prestroke proteomic changes in cerebral microvessels in stroke-prone, transgenic [hCETP]-Hyperlipidemic, Dahl salt-sensitive hypertensive rats. Mol Med. 2001; 17:588-598.
    • (2001) Mol Med , vol.17 , pp. 588-598
    • Bergerat, A.1    Decano, J.2    Wu, C.J.3    Choi, H.4    Nesvizhskii, A.I.5    Moran, A.M.6    Ruiz-Opazo, N.7    Steffen, M.8    Herrera, V.L.9
  • 8
    • 84855297758 scopus 로고    scopus 로고
    • Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents
    • Duman RS, and Voleti B. Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends Neurosci. 2012; 35:47-56.
    • (2012) Trends Neurosci , vol.35 , pp. 47-56
    • Duman, R.S.1    Voleti, B.2
  • 9
    • 33646423317 scopus 로고    scopus 로고
    • Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis
    • Knol MJ, Twisk JW, Beekman AT, Heine RJ, Snoek FJ, and Pouwer F. Depression as a risk factor for the onset of type 2 diabetes mellitus. A meta-analysis. Diabetologia. 2006; 49:837-845.
    • (2006) Diabetologia , vol.49 , pp. 837-845
    • Knol, M.J.1    Twisk, J.W.2    Beekman, A.T.3    Heine, R.J.4    Snoek, F.J.5    Pouwer, F.6
  • 15
    • 20344385026 scopus 로고    scopus 로고
    • Lifetime prevalence and age-ofonset distributions of DSM-IV disorders in the National Comorbidity Survey Replication
    • Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, and Walters EE. Lifetime prevalence and age-ofonset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry. 2005; 62:593-602.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 593-602
    • Kessler, R.C.1    Berglund, P.2    Demler, O.3    Jin, R.4    Merikangas, K.R.5    Walters, E.E.6
  • 16
    • 54049133277 scopus 로고    scopus 로고
    • The molecular neurobiology of depression
    • Krishnan V, and Nestler EJ. The molecular neurobiology of depression. Nature. 2008; 455:894-902.
    • (2008) Nature , vol.455 , pp. 894-902
    • Krishnan, V.1    Nestler, E.J.2
  • 21
    • 0031024060 scopus 로고    scopus 로고
    • Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system
    • Duxon MS, Flanigan TP, Reavley AC, Baxter GS, Blackburn TP, and Fone KC. Evidence for expression of the 5-hydroxytryptamine-2B receptor protein in the rat central nervous system. Neuroscience. 1997; 76:323-329.
    • (1997) Neuroscience , vol.76 , pp. 323-329
    • Duxon, M.S.1    Flanigan, T.P.2    Reavley, A.C.3    Baxter, G.S.4    Blackburn, T.P.5    Fone, K.C.6
  • 25
    • 84871246768 scopus 로고    scopus 로고
    • Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke
    • Buga AM, Scholz CJ, Kumar S, Herndon JG, Alexandru D, Cojocaru GR, Dandekar T, and Popa-Wagner A. Identification of new therapeutic targets by genome-wide analysis of gene expression in the ipsilateral cortex of aged rats after stroke. PLoS ONE. 2012; 7: e50985. doi:10.1371/journal.pone.0050985.
    • (2012) PLoS ONE , vol.7
    • Buga, A.M.1    Scholz, C.J.2    Kumar, S.3    Herndon, J.G.4    Alexandru, D.5    Cojocaru, G.R.6    Dandekar, T.7    Popa-Wagner, A.8
  • 28
    • 0019815904 scopus 로고
    • Brain lactic acidosis and ischemic cell damage: 1. Biochemistry and neurophysiology
    • Rehncrona S, Rosén I, and Siesjö BK. Brain lactic acidosis and ischemic cell damage: 1. Biochemistry and neurophysiology. J Cereb Blood Flow Metab. 1981; 1:297-311.
    • (1981) J Cereb Blood Flow Metab , vol.1 , pp. 297-311
    • Rehncrona, S.1    Rosén, I.2    Siesjö, B.K.3
  • 29
    • 0037006369 scopus 로고    scopus 로고
    • Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test
    • Cryan JF, Page ME, and Lucki I. Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test. Eur J Pharmacol. 2002; 436:197-205.
    • (2002) Eur J Pharmacol , vol.436 , pp. 197-205
    • Cryan, J.F.1    Page, M.E.2    Lucki, I.3
  • 30
    • 8444223161 scopus 로고    scopus 로고
    • Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration
    • Strekalova T, Spanagel R, Bartsch D, Henn FA, and Gass P. Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration. Neuropsychopharmacology. 2004; 29:2007-2017.
    • (2004) Neuropsychopharmacology , vol.29 , pp. 2007-2017
    • Strekalova, T.1    Spanagel, R.2    Bartsch, D.3    Henn, F.A.4    Gass, P.5
  • 31
    • 33947410259 scopus 로고    scopus 로고
    • Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats
    • Popa-Wagner A, Badan I, Walker L, Groppa S, Patrana N, and Kessler C. Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats. Acta Neuropathol. 2007; 113:277-293.
    • (2007) Acta Neuropathol , vol.113 , pp. 277-293
    • Popa-Wagner, A.1    Badan, I.2    Walker, L.3    Groppa, S.4    Patrana, N.5    Kessler, C.6
  • 32
    • 0031595553 scopus 로고    scopus 로고
    • beta-Amyloid precursor protein and ss-amyloid peptide immunoreactivityin the rat brain after middle cerebral arteryocclusion: effect of age
    • Popa-Wagner A, Schroder E, Walker LC, and Kessler C. beta-Amyloid precursor protein and ss-amyloid peptide immunoreactivityin the rat brain after middle cerebral arteryocclusion: effect of age. Stroke. 1998; 29:2196-2202.
    • (1998) Stroke , vol.29 , pp. 2196-2202
    • Popa-Wagner, A.1    Schroder, E.2    Walker, L.C.3    Kessler, C.4
  • 35
    • 84864549499 scopus 로고    scopus 로고
    • Prolonged gaseous hypothermia prevents the upregulation of phagocytosis-specific protein Annexin 1 and causes low amplitude EEG activity in the aged rat brain after cerebral ischemia
    • Joseph C, Buga AM, Vintilescu R, Balseanu AT, Moldovan M, Junker H, Walker L, Lotze M, and Popa-Wagner A. Prolonged gaseous hypothermia prevents the upregulation of phagocytosis-specific protein Annexin 1 and causes low amplitude EEG activity in the aged rat brain after cerebral ischemia. J Cereb Blood Flow Metab. 2012; 32:1632-1642.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1632-1642
    • Joseph, C.1    Buga, A.M.2    Vintilescu, R.3    Balseanu, A.T.4    Moldovan, M.5    Junker, H.6    Walker, L.7    Lotze, M.8    Popa-Wagner, A.9
  • 36
    • 74949123762 scopus 로고    scopus 로고
    • Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation
    • Hawthorne AL, Wylie CJ, Landmesser LT, Deneris ES, and Silver J. Serotonergic neurons migrate radially through the neuroepithelium by dynamin-mediated somal translocation. J Neurosci. 2010;30:420-430.
    • (2010) J Neurosci , vol.30 , pp. 420-430
    • Hawthorne, A.L.1    Wylie, C.J.2    Landmesser, L.T.3    Deneris, E.S.4    Silver, J.5
  • 38
    • 34247513400 scopus 로고    scopus 로고
    • Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi
    • Hattori S, Hashimoto R, Miyakawa T, Yamanaka H, Maeno H, Wada K, and Kunugi H. Enriched environments influence depression-related behavior in adult mice and the survival of newborn cells in their hippocampi. Behav Brain Res. 2007; 180:69-76.
    • (2007) Behav Brain Res , vol.180 , pp. 69-76
    • Hattori, S.1    Hashimoto, R.2    Miyakawa, T.3    Yamanaka, H.4    Maeno, H.5    Wada, K.6    Kunugi, H.7
  • 39
    • 80052759046 scopus 로고    scopus 로고
    • Enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice lacking its expression through promoter IV
    • Jha S, Dong B, and Sakata K. Enriched environment treatment reverses depression-like behavior and restores reduced hippocampal neurogenesis and protein levels of brain-derived neurotrophic factor in mice lacking its expression through promoter IV. Transl Psychiatry. 2011; 1: e40. doi: 10.1038/tp.2011.33.
    • (2011) Transl Psychiatry , vol.1
    • Jha, S.1    Dong, B.2    Sakata, K.3
  • 40
    • 79960618469 scopus 로고    scopus 로고
    • Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network
    • Niebert M, Vogelgesang S, Koch UR, Bischoff AM, Kron M, Bock N, and Manzke T. Expression and function of serotonin 2A and 2B receptors in the mammalian respiratory network.PLoS One. 2011; 6:e21395. doi: 10.1371/journal. pone.0021395.
    • (2011) PLoS One , vol.6
    • Niebert, M.1    Vogelgesang, S.2    Koch, U.R.3    Bischoff, A.M.4    Kron, M.5    Bock, N.6    Manzke, T.7
  • 41
    • 84911477828 scopus 로고    scopus 로고
    • Fluoxetine and all other SSRIs are 5-HT2B Agonists-Importance for their Therapeutic Effects
    • Peng L, Gu L, Li B, and Hertz L. Fluoxetine and all other SSRIs are 5-HT2B Agonists-Importance for their Therapeutic Effects. Curr Neuropharmacol. 2014; 12:365-339.
    • (2014) Curr Neuropharmacol , vol.12 , pp. 365-369
    • Peng, L.1    Gu, L.2    Li, B.3    Hertz, L.4
  • 42
    • 84867511647 scopus 로고    scopus 로고
    • Post-stroke depression: Main phenomenological clusters and their relationships with clinical measures
    • Quaranta D, Marra C, and Gainotti G. Post-stroke depression: Main phenomenological clusters and their relationships with clinical measures. Behav Neurol. 2012; 25:303-310.
    • (2012) Behav Neurol , vol.25 , pp. 303-310
    • Quaranta, D.1    Marra, C.2    Gainotti, G.3
  • 43
    • 80054747799 scopus 로고    scopus 로고
    • C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats
    • Zopf DA, das Neves LA, Nikula KJ, Huang J, Senese PB, and Gralinski MR. C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats. Eur J Pharmacol. 2011; 670:195-203.
    • (2011) Eur J Pharmacol , vol.670 , pp. 195-203
    • Zopf, D.A.1    Das Neves, L.A.2    Nikula, K.J.3    Huang, J.4    Senese, P.B.5    Gralinski, M.R.6
  • 44
    • 0033137332 scopus 로고    scopus 로고
    • Effects of the 5-HT2C/2B antagonist SB 206553 on hyperactivity induced by cocaine
    • McCreary AC, and Cunningham KA. Effects of the 5-HT2C/2B antagonist SB 206553 on hyperactivity induced by cocaine. Neuropsychopharmacology. 1999; 20:556-564.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 556-564
    • McCreary, A.C.1    Cunningham, K.A.2
  • 45
    • 0008670010 scopus 로고    scopus 로고
    • 5-HT drugs and eating disorders
    • Kennett GA. 5-HT drugs and eating disorders. IDrugs. 1998; 1:456-470.
    • (1998) IDrugs , vol.1 , pp. 456-470
    • Kennett, G.A.1
  • 46
    • 33748648565 scopus 로고    scopus 로고
    • Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells
    • Launay JM, Schneider B, Loric S, Da Prada M, and Kellermann O. Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells. FASEB J. 2006; 20:1843-1854.
    • (2006) FASEB J , vol.20 , pp. 1843-1854
    • Launay, J.M.1    Schneider, B.2    Loric, S.3    Da Prada, M.4    Kellermann, O.5
  • 47
    • 40849142489 scopus 로고    scopus 로고
    • Serotonin 5-HT2B receptors are required for 3, 4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro
    • Doly S, Valjent E, Setola V, Callebert J, Hervé D, Launay JM, and Maroteaux L. Serotonin 5-HT2B receptors are required for 3, 4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro. J Neurosci. 2008; 28:2933-2940.
    • (2008) J Neurosci , vol.28 , pp. 2933-2940
    • Doly, S.1    Valjent, E.2    Setola, V.3    Callebert, J.4    Hervé, D.5    Launay, J.M.6    Maroteaux, L.7
  • 50
  • 54
    • 0032993070 scopus 로고    scopus 로고
    • Apathy and depressed mood in acquired brain damage: relationship to lesion localization and psychophysiological reactivity
    • Andersson S, Krogstad JM, and Finset A. Apathy and depressed mood in acquired brain damage: relationship to lesion localization and psychophysiological reactivity. Psychol Med. 1999; 29:447-456.
    • (1999) Psychol Med , vol.29 , pp. 447-456
    • Andersson, S.1    Krogstad, J.M.2    Finset, A.3
  • 55
    • 79951841141 scopus 로고    scopus 로고
    • Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity
    • Murray KC, Stephens MJ, Ballou EW, Heckman CJ, and Bennett DJ. Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. J Neurophysiol. 2011; 105:731-748.
    • (2011) J Neurophysiol , vol.105 , pp. 731-748
    • Murray, K.C.1    Stephens, M.J.2    Ballou, E.W.3    Heckman, C.J.4    Bennett, D.J.5
  • 56
    • 27944444563 scopus 로고    scopus 로고
    • Frequency and clinical, neuropsychological and neuroimaging correlates of apathy following stroke-the Sydney Stroke Study
    • Brodaty H, Sachdev PS, Withall A, Altendorf A, Valenzuela MJ, and Lorentz L. Frequency and clinical, neuropsychological and neuroimaging correlates of apathy following stroke-the Sydney Stroke Study. Psychol Med. 2005; 35:1707-1716.
    • (2005) Psychol Med , vol.35 , pp. 1707-1716
    • Brodaty, H.1    Sachdev, P.S.2    Withall, A.3    Altendorf, A.4    Valenzuela, M.J.5    Lorentz, L.6
  • 57
    • 0035055628 scopus 로고    scopus 로고
    • Apathy, anhedonia, and psychomotor retardation in elderly psychiatric patients and healthy elderly individuals
    • Lampe IK, Kahn RS, and Heeren TJ. Apathy, anhedonia, and psychomotor retardation in elderly psychiatric patients and healthy elderly individuals. J Geriatr Psychiatry Neurol. 2001; 14:11-16.
    • (2001) J Geriatr Psychiatry Neurol , vol.14 , pp. 11-16
    • Lampe, I.K.1    Kahn, R.S.2    Heeren, T.J.3
  • 60
    • 79959953811 scopus 로고    scopus 로고
    • Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells
    • Liu D, Wang Z, Liu S, Wang F, Zhao S, Hao A. Anti-inflammatory effects of fluoxetine in lipopolysaccharide(LPS)-stimulated microglial cells. Neuropharmacology. 2011; 61:592-599.
    • (2011) Neuropharmacology , vol.61 , pp. 592-599
    • Liu, D.1    Wang, Z.2    Liu, S.3    Wang, F.4    Zhao, S.5    Hao, A.6
  • 61
    • 0034671366 scopus 로고    scopus 로고
    • Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
    • Malberg JE, Eisch AJ, Nestler EJ, Duman RS. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci. 2000; 20:9104-9110.
    • (2000) J Neurosci , vol.20 , pp. 9104-9110
    • Malberg, J.E.1    Eisch, A.J.2    Nestler, E.J.3    Duman, R.S.4
  • 62
    • 84958036634 scopus 로고    scopus 로고
    • Fluoxetine Enhances Neurogenesis in Aged Rats with Cortical Infarcts, but this is not Reflected in a Behavioral Recovery
    • Sun X, Zhou Z, Liu T, Zhao M, Zhao S, Xiao T, Jolkkonen J, and Zhao C. Fluoxetine Enhances Neurogenesis in Aged Rats with Cortical Infarcts, but this is not Reflected in a Behavioral Recovery. J Mol Neurosci. 2016; 58:233-42. doi: 10.1007/s12031-015-0662-y.
    • (2016) J Mol Neurosci , vol.58 , pp. 233-242
    • Sun, X.1    Zhou, Z.2    Liu, T.3    Zhao, M.4    Zhao, S.5    Xiao, T.6    Jolkkonen, J.7    Zhao, C.8
  • 64
    • 84858601983 scopus 로고    scopus 로고
    • Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation
    • Hermann DM, and Chopp M. Promoting brain remodelling and plasticity for stroke recovery: therapeutic promise and potential pitfalls of clinical translation. Lancet Neurol. 2012; 11:369-380.
    • (2012) Lancet Neurol , vol.11 , pp. 369-380
    • Hermann, D.M.1    Chopp, M.2
  • 65
    • 78650665522 scopus 로고    scopus 로고
    • Decline in adult neurogenesis during aging follows a topographic pattern in the mouse hippocampus
    • Jinno S. Decline in adult neurogenesis during aging follows a topographic pattern in the mouse hippocampus. J Comp Neurol. 2011; 519:451-466.
    • (2011) J Comp Neurol , vol.519 , pp. 451-466
    • Jinno, S.1
  • 66
    • 4644294031 scopus 로고    scopus 로고
    • Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination
    • Enwere E, Shingo T, Gregg C, Fujikawa H, Ohta S, and Weiss S. Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination. J Neurosci. 2004; 24:8354-8365.
    • (2004) J Neurosci , vol.24 , pp. 8354-8365
    • Enwere, E.1    Shingo, T.2    Gregg, C.3    Fujikawa, H.4    Ohta, S.5    Weiss, S.6
  • 70
    • 61349092383 scopus 로고    scopus 로고
    • Chronic fluoxetine treatment improves ischemia-induced spatial cognitive deficits through increasing hippocampal neurogenesis after stroke
    • Li WL, Cai HH, Wang B, Chen L, Zhou QG, Luo CX, Liu N, Ding XS, Zhu DY. Chronic fluoxetine treatment improves ischemia-induced spatial cognitive deficits through increasing hippocampal neurogenesis after stroke. J Neurosci Res. 2009; 87:112-122.
    • (2009) J Neurosci Res , vol.87 , pp. 112-122
    • Li, W.L.1    Cai, H.H.2    Wang, B.3    Chen, L.4    Zhou, Q.G.5    Luo, C.X.6    Liu, N.7    Ding, X.S.8    Zhu, D.Y.9
  • 72
    • 84946423581 scopus 로고    scopus 로고
    • Neurogenesis following Stroke Affecting the Adult Brain
    • Lindvall O, Kokaia Z. Neurogenesis following Stroke Affecting the Adult Brain. Cold Spring Harb Perspect Biol. 2015; 7. pii: a019034. doi:10.1101/cshperspect.a019034.
    • (2015) Cold Spring Harb Perspect Biol , vol.7
    • Lindvall, O.1    Kokaia, Z.2


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