-
1
-
-
84871051576
-
Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the Global Burden of Disease Study 2010
-
Vos, T. et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 380, 2163-2196 (2012)
-
(2012)
Lancet
, vol.380
, pp. 2163-2196
-
-
Vos, T.1
-
2
-
-
84940447040
-
Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013
-
Vos, T. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 386, 743-800 (2015)
-
(2015)
Lancet
, vol.386
, pp. 743-800
-
-
Vos, T.1
-
3
-
-
80053496448
-
Cost of disorders of the brain in Europe 2010
-
Gustavsson, A. et al. Cost of disorders of the brain in Europe 2010. Eur. Neuropsychopharmacol. 21, 718-779 (2011)
-
(2011)
Eur. Neuropsychopharmacol
, vol.21
, pp. 718-779
-
-
Gustavsson, A.1
-
4
-
-
0038544557
-
Neurological diseases: Neurobiology of migraine
-
Pietrobon, D. &Striessnig, J. Neurological diseases: neurobiology of migraine. Nat. Rev. Neurosci. 4, 386-398 (2003)
-
(2003)
Nat. Rev. Neurosci
, vol.4
, pp. 386-398
-
-
Pietrobon, D.1
Striessnig, J.2
-
5
-
-
79955375829
-
One hundred years of migraine research: Major clinical and scientific observations from 1910 to 2010
-
Tfelt-Hansen, P.C. &Koehler, P.J. One hundred years of migraine research: major clinical and scientific observations from 1910 to 2010. Headache 51, 752-778 (2011)
-
(2011)
Headache
, vol.51
, pp. 752-778
-
-
Tfelt-Hansen, P.C.1
Koehler, P.J.2
-
6
-
-
84879990242
-
Headache Classification Committee of the International Headache Society (IHS) the International Classification of Headache Disorders, 3rd edition (beta version)
-
Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition (beta version). Cephalalgia 33, 629-808 (2013)
-
(2013)
Cephalalgia
, vol.33
, pp. 629-808
-
-
-
7
-
-
84933279742
-
Meta-analysis of the heritability of human traits based on fifty years of twin studies
-
Polderman, T.J.C. et al. Meta-analysis of the heritability of human traits based on fifty years of twin studies. Nat. Genet. 47, 702-709 (2015)
-
(2015)
Nat. Genet
, vol.47
, pp. 702-709
-
-
Polderman, T.J.C.1
-
8
-
-
77957598638
-
Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1
-
Anttila, V. et al. Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat. Genet. 42, 869-873 (2010)
-
(2010)
Nat. Genet
, vol.42
, pp. 869-873
-
-
Anttila, V.1
-
9
-
-
79959721099
-
Genome-wide association study reveals three susceptibility loci for common migraine in the general population
-
Chasman, D.I. et al. Genome-wide association study reveals three susceptibility loci for common migraine in the general population. Nat. Genet. 43, 695-698 (2011)
-
(2011)
Nat. Genet
, vol.43
, pp. 695-698
-
-
Chasman, D.I.1
-
10
-
-
84862976129
-
Genome-wide association analysis identifies susceptibility loci for migraine without aura
-
Freilinger, T. et al. Genome-wide association analysis identifies susceptibility loci for migraine without aura. Nat. Genet. 44, 777-782 (2012)
-
(2012)
Nat. Genet
, vol.44
, pp. 777-782
-
-
Freilinger, T.1
-
11
-
-
84881022482
-
Genome-wide meta-analysis identifies new susceptibility loci for migraine
-
Anttila, V. et al. Genome-wide meta-analysis identifies new susceptibility loci for migraine. Nat. Genet. 45, 912-917 (2013)
-
(2013)
Nat. Genet
, vol.45
, pp. 912-917
-
-
Anttila, V.1
-
12
-
-
16044370232
-
Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4
-
Ophoff, R.A. et al. Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4. Cell 87, 543-552 (1996)
-
(1996)
Cell
, vol.87
, pp. 543-552
-
-
Ophoff, R.A.1
-
13
-
-
0037312922
-
Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump α2 subunit associated with familial hemiplegic migraine type 2
-
De Fusco, M. et al. Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump α2 subunit associated with familial hemiplegic migraine type 2. Nat. Genet. 33, 192-196 (2003)
-
(2003)
Nat. Genet
, vol.33
, pp. 192-196
-
-
De Fusco, M.1
-
14
-
-
23044459961
-
Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine
-
Dichgans, M. et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet 366, 371-377 (2005)
-
(2005)
Lancet
, vol.366
, pp. 371-377
-
-
Dichgans, M.1
-
15
-
-
54449084257
-
A high-density association screen of 155 ion transport genes for involvement with common migraine
-
Nyholt, D.R. et al. A high-density association screen of 155 ion transport genes for involvement with common migraine. Hum. Mol. Genet. 17, 3318-3331 (2008)
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 3318-3331
-
-
Nyholt, D.R.1
-
16
-
-
84975795680
-
An integrated map of genetic variation from 1,092 human genomes
-
1000 Genomes Project Consortium et al. An integrated map of genetic variation from 1,092 human genomes. Nature 491, 56-65 (2012)
-
(2012)
Nature
, vol.491
, pp. 56-65
-
-
1000 Genomes Project Consortium et al1
-
17
-
-
84901630159
-
Selectivity in genetic association with sub-classified migraine in women
-
Chasman, D.I. et al. Selectivity in genetic association with sub-classified migraine in women. PLoS Genet. 10, e1004366 (2014)
-
(2014)
PLoS Genet
, vol.10
, pp. e1004366
-
-
Chasman, D.I.1
-
18
-
-
79955860273
-
Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
-
Han, B. &Eskin, E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet. 88, 586-598 (2011)
-
(2011)
Am. J. Hum. Genet
, vol.88
, pp. 586-598
-
-
Han, B.1
Eskin, E.2
-
19
-
-
27644497116
-
PH sensing in the two-pore domain K+ channel, TASK2
-
Morton, M.J., Abohamed, A., Sivaprasadarao, A. &Hunter, M. pH sensing in the two-pore domain K+ channel, TASK2. Proc. Natl. Acad. Sci. USA 102, 16102-16106 (2005)
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 16102-16106
-
-
Morton, M.J.1
Abohamed, A.2
Sivaprasadarao, A.3
Hunter, M.4
-
20
-
-
84876908893
-
TRPM8 activation attenuates inflammatory responses in mouse models of colitis
-
Ramachandran, R. et al. TRPM8 activation attenuates inflammatory responses in mouse models of colitis. Proc. Natl. Acad. Sci. USA 110, 7476-7481 (2013)
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 7476-7481
-
-
Ramachandran, R.1
-
21
-
-
33646243805
-
Genetic neurological channelopathies
-
Hanna, M.G. Genetic neurological channelopathies. Nat. Clin. Pract. Neurol. 2, 252-263 (2006)
-
(2006)
Nat. Clin. Pract. Neurol
, vol.2
, pp. 252-263
-
-
Hanna, M.G.1
-
22
-
-
0035933855
-
Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3
-
Kraev, A. et al. Molecular cloning of a third member of the potassium-dependent sodium-calcium exchanger gene family, NCKX3. J. Biol. Chem. 276, 23161-23172 (2001)
-
(2001)
J. Biol. Chem
, vol.276
, pp. 23161-23172
-
-
Kraev, A.1
-
23
-
-
0029830687
-
A biologic function for an 'orphan' messenger: D-myo-inositol 3,4,5,6-tetrakisphosphate selectively blocks epithelial calcium-activated chloride channels
-
Ismailov, I.I. et al. A biologic function for an 'orphan' messenger: D-myo-inositol 3,4,5,6-tetrakisphosphate selectively blocks epithelial calcium-activated chloride channels. Proc. Natl. Acad. Sci. USA 93, 10505-10509 (1996)
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10505-10509
-
-
Ismailov, I.I.1
-
24
-
-
80052404768
-
Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability
-
De Bock, M. et al. Connexin channels provide a target to manipulate brain endothelial calcium dynamics and blood-brain barrier permeability. J. Cereb. Blood Flow Metab. 31, 1942-1957 (2011)
-
(2011)
J. Cereb. Blood Flow Metab
, vol.31
, pp. 1942-1957
-
-
De Bock, M.1
-
25
-
-
70749096913
-
Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
-
Kathiresan, S. et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants. Nat. Genet. 41, 334-341 (2009)
-
(2009)
Nat. Genet
, vol.41
, pp. 334-341
-
-
Kathiresan, S.1
-
26
-
-
84928478209
-
Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection
-
Debette, S. et al. Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection. Nat. Genet. 47, 78-83 (2015)
-
(2015)
Nat. Genet
, vol.47
, pp. 78-83
-
-
Debette, S.1
-
27
-
-
33846163129
-
Clinical features in a family with an R460H mutation in transforming growth factor β receptor 2 gene
-
Law, C. et al. Clinical features in a family with an R460H mutation in transforming growth factor β receptor 2 gene. J. Med. Genet. 43, 908-916 (2006)
-
(2006)
J. Med. Genet
, vol.43
, pp. 908-916
-
-
Law, C.1
-
28
-
-
84945173643
-
Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1
-
Bown, M.J. et al. Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1. Am. J. Hum. Genet. 89, 619-627 (2011)
-
(2011)
Am. J. Hum. Genet
, vol.89
, pp. 619-627
-
-
Bown, M.J.1
-
29
-
-
84880268274
-
Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy
-
Arndt, A.K. et al. Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy. Am. J. Hum. Genet. 93, 67-77 (2013)
-
(2013)
Am. J. Hum. Genet
, vol.93
, pp. 67-77
-
-
Arndt, A.K.1
-
30
-
-
84915770152
-
Genetics and biomarkers of Moyamoya disease: Significance of RNF213 as a susceptibility gene
-
Fujimura, M. et al. Genetics and biomarkers of Moyamoya disease: significance of RNF213 as a susceptibility gene. J. Stroke 16, 65-72 (2014)
-
(2014)
J. Stroke
, vol.16
, pp. 65-72
-
-
Fujimura, M.1
-
31
-
-
0037069322
-
Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome
-
McElhinney, D.B. et al. Analysis of cardiovascular phenotype and genotype-phenotype correlation in individuals with a JAG1 mutation and/or Alagille syndrome. Circulation 106, 2567-2574 (2002)
-
(2002)
Circulation
, vol.106
, pp. 2567-2574
-
-
McElhinney, D.B.1
-
32
-
-
84883461171
-
Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death
-
Bezzina, C.R. et al. Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat. Genet. 45, 1044-1049 (2013)
-
(2013)
Nat. Genet
, vol.45
, pp. 1044-1049
-
-
Bezzina, C.R.1
-
33
-
-
84922637956
-
Integrating genetic, transcriptional, and functional analyses to identify five novel genes for atrial fibrillation
-
Sinner, M.F. et al. Integrating genetic, transcriptional, and functional analyses to identify five novel genes for atrial fibrillation. Circulation 130, 1225-1235 (2014)
-
(2014)
Circulation
, vol.130
, pp. 1225-1235
-
-
Sinner, M.F.1
-
34
-
-
77952120581
-
Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC)
-
Neale, B.M. et al. Genome-wide association study of advanced age-related macular degeneration identifies a role of the hepatic lipase gene (LIPC). Proc. Natl. Acad. Sci. USA 107, 7395-7400 (2010)
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 7395-7400
-
-
Neale, B.M.1
-
35
-
-
77952345697
-
IRAG determines nitric oxide-and atrial natriuretic peptide-mediated smooth muscle relaxation
-
Desch, M. et al. IRAG determines nitric oxide-and atrial natriuretic peptide-mediated smooth muscle relaxation. Cardiovasc. Res. 86, 496-505 (2010)
-
(2010)
Cardiovasc. Res
, vol.86
, pp. 496-505
-
-
Desch, M.1
-
36
-
-
33846987217
-
Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women
-
Lang, N.N., Luksha, L., Newby, D.E. &Kublickiene, K. Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women. Am. J. Physiol. Heart Circ. Physiol. 292, H1026-H1032 (2007)
-
(2007)
Am. J. Physiol. Heart Circ. Physiol
, vol.292
, pp. H1026-H1032
-
-
Lang, N.N.1
Luksha, L.2
Newby, D.E.3
Kublickiene, K.4
-
37
-
-
33748432441
-
Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle
-
Dong, H., Jiang, Y., Triggle, C.R., Li, X. &Lytton, J. Novel role for K+-dependent Na+/Ca2+ exchangers in regulation of cytoplasmic free Ca2+ and contractility in arterial smooth muscle. Am. J. Physiol. Heart Circ. Physiol. 291, H1226-H1235 (2006)
-
(2006)
Am. J. Physiol. Heart Circ. Physiol
, vol.291
, pp. H1226-H1235
-
-
Dong, H.1
Jiang, Y.2
Triggle, C.R.3
Li, X.4
Lytton, J.5
-
38
-
-
84922696110
-
Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice
-
Yamaji, M., Mahmoud, M., Evans, I.M. &Zachary, I.C. Neuropilin 1 is essential for gastrointestinal smooth muscle contractility and motility in aged mice. PLoS One 10, e0115563 (2015)
-
(2015)
PLoS One
, vol.10
, pp. e0115563
-
-
Yamaji, M.1
Mahmoud, M.2
Evans, I.M.3
Zachary, I.C.4
-
39
-
-
84864407698
-
Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease
-
Lu, X. et al. Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease. Nat. Genet. 44, 890-894 (2012)
-
(2012)
Nat. Genet
, vol.44
, pp. 890-894
-
-
Lu, X.1
-
40
-
-
84862682331
-
Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis
-
Hager, J. et al. Genome-wide association study in a Lebanese cohort confirms PHACTR1 as a major determinant of coronary artery stenosis. PLoS One 7, e38663 (2012)
-
(2012)
PLoS One
, vol.7
, pp. e38663
-
-
Hager, J.1
-
41
-
-
79953221100
-
A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease
-
The Coronary Artery Disease (C4D) Genetics Consortium. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease. Nat. Genet. 43, 339-344 (2011)
-
(2011)
Nat. Genet
, vol.43
, pp. 339-344
-
-
The Coronary Artery Disease (C4D) Genetics Consortium1
-
42
-
-
84155163079
-
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction
-
O'Donnell, C.J. et al. Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation 124, 2855-2864 (2011)
-
(2011)
Circulation
, vol.124
, pp. 2855-2864
-
-
O'Donnell, C.J.1
-
43
-
-
84874781557
-
A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function
-
Porcu, E. et al. A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function. PLoS Genet. 9, e1003266 (2013)
-
(2013)
PLoS Genet
, vol.9
, pp. e1003266
-
-
Porcu, E.1
-
44
-
-
80055008094
-
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
-
Soler Artigas, M. et al. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. Nat. Genet. 43, 1082-1090 (2011)
-
(2011)
Nat. Genet
, vol.43
, pp. 1082-1090
-
-
Soler, A.M.1
-
45
-
-
84897386660
-
REST and stress resistance in ageing and Alzheimer disease
-
Lu, T. et al. REST and stress resistance in ageing and Alzheimer disease. Nature 507, 448-454 (2014)
-
(2014)
Nature
, vol.507
, pp. 448-454
-
-
Lu, T.1
-
46
-
-
84879239589
-
Connexin 43 channels protect osteocytes against oxidative stress-induced cell death
-
Kar, R., Riquelme, M.A., Werner, S. &Jiang, J.X. Connexin 43 channels protect osteocytes against oxidative stress-induced cell death. J. Bone Miner. Res. 28, 1611-1621 (2013)
-
(2013)
J. Bone Miner. Res
, vol.28
, pp. 1611-1621
-
-
Kar, R.1
Riquelme, M.A.2
Werner, S.3
Jiang, J.X.4
-
47
-
-
84901037002
-
Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism
-
Dixit, D., Ghildiyal, R., Anto, N.P. &Sen, E. Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism. Cell Death Dis. 5, e1212 (2014)
-
(2014)
Cell Death Dis
, vol.5
, pp. e1212
-
-
Dixit, D.1
Ghildiyal, R.2
Anto, N.P.3
Sen, E.4
-
48
-
-
77957551487
-
Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress
-
Chuikov, S., Levi, B.P., Smith, M.L. &Morrison, S.J. Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat. Cell Biol. 12, 999-1006 (2010)
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 999-1006
-
-
Chuikov, S.1
Levi, B.P.2
Smith, M.L.3
Morrison, S.J.4
-
49
-
-
79957440298
-
Hypoxia stimulates low-density lipoprotein receptor-related protein-1 expression through hypoxia-inducible factor-1α in human vascular smooth muscle cells
-
Castellano, J. et al. Hypoxia stimulates low-density lipoprotein receptor-related protein-1 expression through hypoxia-inducible factor-1α in human vascular smooth muscle cells. Arterioscler. Thromb. Vasc. Biol. 31, 1411-1420 (2011)
-
(2011)
Arterioscler. Thromb. Vasc. Biol
, vol.31
, pp. 1411-1420
-
-
Castellano, J.1
-
50
-
-
0034624696
-
Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase I&beta
-
Schlossmann, J. et al. Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Iβ. Nature 404, 197-201 (2000)
-
(2000)
Nature
, vol.404
, pp. 197-201
-
-
Schlossmann, J.1
-
51
-
-
84939599004
-
Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
-
Nalls, M.A. et al. Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease. Nat. Genet. 46, 989-993 (2014)
-
(2014)
Nat. Genet
, vol.46
, pp. 989-993
-
-
Nalls, M.A.1
-
52
-
-
84888317489
-
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
-
Lambert, J.C. et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat. Genet. 45, 1452-1458 (2013)
-
(2013)
Nat. Genet
, vol.45
, pp. 1452-1458
-
-
Lambert, J.C.1
-
54
-
-
84908890496
-
Defining the role of common variation in the genomic and biological architecture of adult human height
-
Wood, A.R. et al. Defining the role of common variation in the genomic and biological architecture of adult human height. Nat. Genet. 46, 1173-1186 (2014)
-
(2014)
Nat. Genet
, vol.46
, pp. 1173-1186
-
-
Wood, A.R.1
-
55
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell, S. et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81, 559-575 (2007)
-
(2007)
Am. J. Hum. Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
-
56
-
-
84923946495
-
LD score regression distinguishes confounding from polygenicity in genome-wide association studies
-
Bulik-Sullivan, B.K. et al. LD score regression distinguishes confounding from polygenicity in genome-wide association studies. Nat. Genet. 47, 291-295 (2015)
-
(2015)
Nat. Genet
, vol.47
, pp. 291-295
-
-
Bulik-Sullivan, B.K.1
-
57
-
-
79959241413
-
Genomic inflation factors under polygenic inheritance
-
Yang, J. et al. Genomic inflation factors under polygenic inheritance. Eur. J. Hum. Genet. 19, 807-812 (2011)
-
(2011)
Eur. J. Hum. Genet
, vol.19
, pp. 807-812
-
-
Yang, J.1
-
58
-
-
78649505227
-
Meta-analysis of sex-specific genome-wide association studies
-
Magi, R., Lindgren, C.M. &Morris, A.P. Meta-analysis of sex-specific genome-wide association studies. Genet. Epidemiol. 34, 846-853 (2010)
-
(2010)
Genet. Epidemiol
, vol.34
, pp. 846-853
-
-
Magi, R.1
Lindgren, C.M.2
Morris, A.P.3
-
59
-
-
84870502629
-
Bayesian refinement of association signals for 14 loci in 3 common diseases
-
Maller, J.B. et al. Bayesian refinement of association signals for 14 loci in 3 common diseases. Nat. Genet. 44, 1294-1301 (2012)
-
(2012)
Nat. Genet
, vol.44
, pp. 1294-1301
-
-
Maller, J.B.1
-
60
-
-
77951439152
-
Trait-associated SNPs are more likely to be eQTLs: Annotation to enhance discovery from GWAS
-
Nicolae, D.L. et al. Trait-associated SNPs are more likely to be eQTLs: annotation to enhance discovery from GWAS. PLoS Genet. 6, e1000888 (2010)
-
(2010)
PLoS Genet
, vol.6
, pp. e1000888
-
-
Nicolae, D.L.1
-
61
-
-
84865822182
-
Systematic localization of common disease-associated variation in regulatory DNA
-
Maurano, M.T. et al. Systematic localization of common disease-associated variation in regulatory DNA. Science 337, 1190-1195 (2012)
-
(2012)
Science
, vol.337
, pp. 1190-1195
-
-
Maurano, M.T.1
-
62
-
-
84878682420
-
The Genotype-Tissue Expression (GTEx) project
-
The GTEx Consortium. The Genotype-Tissue Expression (GTEx) project. Nat. Genet. 45, 580-585 (2013)
-
(2013)
Nat. Genet
, vol.45
, pp. 580-585
-
-
The GTEx Consortium1
-
63
-
-
84923096381
-
Biological interpretation of genome-wide association studies using predicted gene functions
-
Pers, T.H. et al. Biological interpretation of genome-wide association studies using predicted gene functions. Nat. Commun. 6, 5890 (2015)
-
(2015)
Nat. Commun
, vol.6
, pp. 5890
-
-
Pers, T.H.1
-
64
-
-
34848815630
-
Gene expression programs of human smooth muscle cells: Tissue-specific differentiation and prognostic significance in breast cancers
-
Chi, J.T. et al. Gene expression programs of human smooth muscle cells: tissue-specific differentiation and prognostic significance in breast cancers. PLoS Genet. 3, 1770-1784 (2007)
-
(2007)
PLoS Genet
, vol.3
, pp. 1770-1784
-
-
Chi, J.T.1
-
65
-
-
77957940722
-
The NIH Roadmap Epigenomics Mapping Consortium
-
Bernstein, B.E. et al. The NIH Roadmap Epigenomics Mapping Consortium. Nat. Biotechnol. 28, 1045-1048 (2010)
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 1045-1048
-
-
Bernstein, B.E.1
-
66
-
-
84865790047
-
An integrated encyclopedia of DNA elements in the human genome
-
The ENCODE Project Consortium. An integrated encyclopedia of DNA elements in the human genome. Nature 489, 57-74 (2012)
-
(2012)
Nature
, vol.489
, pp. 57-74
-
-
The ENCODE Project Consortium1
-
67
-
-
84962516331
-
Genetic analysis for a shared biological basis between migraine and coronary artery disease
-
Winsvold, B.S. et al. Genetic analysis for a shared biological basis between migraine and coronary artery disease. Neurol. Genet. 1, e10 (2015)
-
(2015)
Neurol. Genet
, vol.1
, pp. e10
-
-
Winsvold, B.S.1
-
68
-
-
84929932178
-
Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants
-
Malik, R. et al. Shared genetic basis for migraine and ischemic stroke: a genome-wide analysis of common variants. Neurology 84, 2132-2145 (2015)
-
(2015)
Neurology
, vol.84
, pp. 2132-2145
-
-
Malik, R.1
-
69
-
-
84918530852
-
Migraine pathophysiology: Lessons from mouse models and human genetics
-
Ferrari, M.D., Klever, R.R., Terwindt, G.M., Ayata, C. &van den Maagdenberg, A.M.J.M. Migraine pathophysiology: lessons from mouse models and human genetics. Lancet Neurol. 14, 65-80 (2015)
-
(2015)
Lancet Neurol
, vol.14
, pp. 65-80
-
-
Ferrari, M.D.1
Klever, R.R.2
Terwindt, G.M.3
Ayata, C.4
Van Den Maagdenberg, A.M.J.M.5
-
70
-
-
67649598903
-
Origin of pain in migraine: Evidence for peripheral sensitisation
-
Olesen, J., Burstein, R., Ashina, M. &Tfelt-Hansen, P. Origin of pain in migraine: evidence for peripheral sensitisation. Lancet Neurol. 8, 679-690 (2009)
-
(2009)
Lancet Neurol
, vol.8
, pp. 679-690
-
-
Olesen, J.1
Burstein, R.2
Ashina, M.3
Tfelt-Hansen, P.4
-
71
-
-
0035836628
-
Mechanisms of migraine aura revealed by functional MRI in human visual cortex
-
Hadjikhani, N. et al. Mechanisms of migraine aura revealed by functional MRI in human visual cortex. Proc. Natl. Acad. Sci. USA 98, 4687-4692 (2001)
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 4687-4692
-
-
Hadjikhani, N.1
-
73
-
-
55149086558
-
The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache
-
Olesen, J. The role of nitric oxide (NO) in migraine, tension-type headache and cluster headache. Pharmacol. Ther. 120, 157-171 (2008)
-
(2008)
Pharmacol. Ther
, vol.120
, pp. 157-171
-
-
Olesen, J.1
-
74
-
-
84877995374
-
Pearls and pitfalls in human pharmacological models of migraine: 30 years' experience
-
Ashina, M., Hansen, J.M. &Olesen, J. Pearls and pitfalls in human pharmacological models of migraine: 30 years' experience. Cephalalgia 33, 540-553 (2013)
-
(2013)
Cephalalgia
, vol.33
, pp. 540-553
-
-
Ashina, M.1
Hansen, J.M.2
Olesen, J.3
-
75
-
-
0034617377
-
Sumatriptan modifies cortical free radical release during cortical spreading depression: A novel antimigraine action for sumatriptan?
-
Read, S.J. &Parsons, A.A. Sumatriptan modifies cortical free radical release during cortical spreading depression: a novel antimigraine action for sumatriptan? Brain Res. 870, 44-53 (2000)
-
(2000)
Brain Res
, vol.870
, pp. 44-53
-
-
Read, S.J.1
Parsons, A.A.2
-
76
-
-
78651100696
-
Data quality control in genetic case-control association studies
-
Anderson, C.A. et al. Data quality control in genetic case-control association studies. Nat. Protoc. 5, 1564-1573 (2010)
-
(2010)
Nat. Protoc
, vol.5
, pp. 1564-1573
-
-
Anderson, C.A.1
-
77
-
-
84899540947
-
Quality control and conduct of genome-wide association meta-analyses
-
Winkler, T.W. et al. Quality control and conduct of genome-wide association meta-analyses. Nat. Protoc. 9, 1192-1212 (2014)
-
(2014)
Nat. Protoc
, vol.9
, pp. 1192-1212
-
-
Winkler, T.W.1
-
78
-
-
84856478855
-
A linear complexity phasing method for thousands of genomes
-
Delaneau, O., Marchini, J. &Zagury, J.-F. A linear complexity phasing method for thousands of genomes. Nat. Methods 9, 179-181 (2011)
-
(2011)
Nat. Methods
, vol.9
, pp. 179-181
-
-
Delaneau, O.1
Marchini, J.2
Zagury, J.-F.3
-
79
-
-
84864417548
-
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
-
Howie, B., Fuchsberger, C., Stephens, M., Marchini, J. &Abecasis, G.R. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat. Genet. 44, 955-959 (2012)
-
(2012)
Nat. Genet
, vol.44
, pp. 955-959
-
-
Howie, B.1
Fuchsberger, C.2
Stephens, M.3
Marchini, J.4
Abecasis, G.R.5
-
80
-
-
35348817330
-
Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering
-
Browning, S.R. &Browning, B.L. Rapid and accurate haplotype phasing and missing-data inference for whole-genome association studies by use of localized haplotype clustering. Am. J. Hum. Genet. 81, 1084-1097 (2007)
-
(2007)
Am. J. Hum. Genet
, vol.81
, pp. 1084-1097
-
-
Browning, S.R.1
Browning, B.L.2
-
81
-
-
78649508578
-
Mach: Using sequence and genotype data to estimate haplotypes and unobserved genotypes
-
Li, Y., Willer, C.J., Ding, J., Scheet, P. &Abecasis, G.R. MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet. Epidemiol. 34, 816-834 (2010)
-
(2010)
Genet. Epidemiol
, vol.34
, pp. 816-834
-
-
Li, Y.1
Willer, C.J.2
Ding, J.3
Scheet, P.4
Abecasis, G.R.5
-
82
-
-
84925937250
-
Minimac2: Faster genotype imputation
-
Fuchsberger, C., Abecasis, G.R. &Hinds, D.A. minimac2: faster genotype imputation. Bioinformatics 31, 782-784 (2015)
-
(2015)
Bioinformatics
, vol.31
, pp. 782-784
-
-
Fuchsberger, C.1
Abecasis, G.R.2
Hinds, D.A.3
-
83
-
-
77956331627
-
Integrating common and rare genetic variation in diverse human populations
-
The International HapMap 3 Consortium. Integrating common and rare genetic variation in diverse human populations. Nature 467, 52-58 (2010)
-
(2010)
Nature
, vol.467
, pp. 52-58
-
-
The International HapMap 3 Consortium1
-
84
-
-
0000120766
-
Estimating the dimension of a model
-
Schwarz, G. Estimating the dimension of a model. Ann. Stat. 6, 461-464 (1978)
-
(1978)
Ann. Stat
, vol.6
, pp. 461-464
-
-
Schwarz, G.1
-
85
-
-
84899642574
-
Heritability and genomics of gene expression in peripheral blood
-
Wright, F.A. et al. Heritability and genomics of gene expression in peripheral blood. Nat. Genet. 46, 430-437 (2014)
-
(2014)
Nat. Genet
, vol.46
, pp. 430-437
-
-
Wright, F.A.1
-
86
-
-
84856228535
-
Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain
-
Richards, A.L. et al. Schizophrenia susceptibility alleles are enriched for alleles that affect gene expression in adult human brain. Mol. Psychiatry 17, 193-201 (2012)
-
(2012)
Mol. Psychiatry
, vol.17
, pp. 193-201
-
-
Richards, A.L.1
-
87
-
-
1842539516
-
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other
-
Nyholt, D.R. A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am. J. Hum. Genet. 74, 765-769 (2004)
-
(2004)
Am. J Hum Genet
, vol.74
, pp. 765-769
-
-
Nyholt, D.R.1
-
88
-
-
84923326765
-
Genetic and epigenetic fine mapping of causal autoimmune disease variants
-
Farh, K.K.-H. et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518, 337-343 (2015)
-
(2015)
Nature
, vol.518
, pp. 337-343
-
-
Farh, K.K.-H.1
-
89
-
-
84892511644
-
Large-scale gene function analysis with the PANTHER classification system
-
Mi, H., Muruganujan, A., Casagrande, J.T. &Thomas, P.D. Large-scale gene function analysis with the PANTHER classification system. Nat. Protoc. 8, 1551-1566 (2013)
-
(2013)
Nat. Protoc
, vol.8
, pp. 1551-1566
-
-
Mi, H.1
Muruganujan, A.2
Casagrande, J.T.3
Thomas, P.D.4
-
90
-
-
84964308876
-
Gene expression analysis identifies global gene dosage sensitivity in cancer
-
Fehrmann, R.S.N. et al. Gene expression analysis identifies global gene dosage sensitivity in cancer. Nat. Genet. 47, 115-125 (2015)
-
(2015)
Nat. Genet
, vol.47
, pp. 115-125
-
-
Fehrmann, R.S.N.1
-
91
-
-
33847172327
-
Clustering by passing messages between data points
-
Frey, B.J. &Dueck, D. Clustering by passing messages between data points. Science 315, 972-976 (2007)
-
(2007)
Science
, vol.315
, pp. 972-976
-
-
Frey, B.J.1
Dueck, D.2
|