IGF-1 protects dopamine neurons against oxidative stress: association with changes in phosphokinases

Experimental Brain Research

Volumn 234, Issue 7, 2016, Pages 1863-1873

  Ayadi, Amina El ^a,b   Zigmond, Michael J ^a   Smith, Amanda D ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

Author keywords

6 OHDA; Akt; CREB; ERK1 2; GSK 3Beta; Parkinson s disease; Striatum

Indexed keywords

DOPAMINE; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B; RAS PROTEIN; SERINE; SOMATOMEDIN C; TYROSINE 3 MONOOXYGENASE; ADRENERGIC RECEPTOR STIMULATING AGENT; NEUROPROTECTIVE AGENT; OXIDOPAMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; IMMUNOREACTIVITY; MALE; NEUROPROTECTION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PHENOTYPE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; ANIMAL; DISEASE MODEL; DRUG EFFECTS; MAPK SIGNALING; METABOLISM; NEOSTRIATUM; PARKINSONIAN DISORDERS; SPRAGUE DAWLEY RAT;

ADRENERGIC AGENTS; ANIMALS; DISEASE MODELS, ANIMAL; DOPAMINERGIC NEURONS; GLYCOGEN SYNTHASE KINASE 3 BETA; INSULIN-LIKE GROWTH FACTOR I; MALE; MAP KINASE SIGNALING SYSTEM; NEOSTRIATUM; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; OXIDOPAMINE; PARKINSONIAN DISORDERS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE;

EID: 84975263365     PISSN: 00144819     EISSN: 14321106     Source Type: Journal    
DOI: 10.1007/s00221-016-4572-1     Document Type: Article

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