메뉴 건너뛰기




Volumn 17, Issue 10, 2016, Pages 1339-1349

Maintenance therapy options for ulcerative colitis

Author keywords

adalimumab; azathioprine; biosimilar; golimumab and vedolizumab; infliximab; mercaptopurine; mesalamine; Ulcerative colitis

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; BIOSIMILAR AGENT; GOLIMUMAB; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; SALICYLIC ACID DERIVATIVE; VEDOLIZUMAB; ANTIINFLAMMATORY AGENT; BIOLOGICAL PRODUCT; IMMUNOLOGIC FACTOR; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR;

EID: 84975259862     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1080/14656566.2016.1187132     Document Type: Review
Times cited : (24)

References (84)
  • 1
    • 84869083669 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis
    • Dec
    • A.Dignass, R.Eliakim, F.Magro, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 1: definitions and diagnosis. J Crohns Colitis. 2012 Dec;6(10):965–990.•• Recommendations from the European Crohn’s and Colitis Organisation.
    • (2012) J Crohns Colitis , vol.6 , Issue.10 , pp. 965-990
    • Dignass, A.1    Eliakim, R.2    Magro, F.3
  • 2
    • 84908472168 scopus 로고    scopus 로고
    • European evidence based consensus on surgery for ulcerative colitis
    • Jan
    • T.Oresland, W.A.Bemelman, G.M.Sampietro, et al. European evidence based consensus on surgery for ulcerative colitis. J Crohns Colitis. 2015 Jan;9(1):4–25.•• Recommendations from the European Crohn’s and Colitis Organisation.
    • (2015) J Crohns Colitis , vol.9 , Issue.1 , pp. 4-25
    • Oresland, T.1    Bemelman, W.A.2    Sampietro, G.M.3
  • 3
    • 84869089859 scopus 로고    scopus 로고
    • Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management
    • Dec
    • A.Dignass, J.O.Lindsay, A.Sturm, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 2: current management. J Crohns Colitis. 2012 Dec;6(10):991–1030.•• Recommendations from the European Crohn’s and Colitis Organisation.
    • (2012) J Crohns Colitis , vol.6 , Issue.10 , pp. 991-1030
    • Dignass, A.1    Lindsay, J.O.2    Sturm, A.3
  • 4
    • 0028338424 scopus 로고
    • Course of ulcerative colitis: analysis of changes in disease activity over years
    • Jul
    • E.Langholz, P.Munkholm, M.Davidsen, et al. Course of ulcerative colitis: analysis of changes in disease activity over years. Gastroenterology. 1994 Jul;107(1):3–11.
    • (1994) Gastroenterology , vol.107 , Issue.1 , pp. 3-11
    • Langholz, E.1    Munkholm, P.2    Davidsen, M.3
  • 5
    • 67049137968 scopus 로고    scopus 로고
    • Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort (IBSEN Study)
    • I.C.Solberg, I.Lygren, J.Jahnsen, et al. Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort (IBSEN Study). Scand J Gastroenterol. 2009;44(4):431–440.•• Recommendations from the European Crohn’s and Colitis Organisation.
    • (2009) Scand J Gastroenterol , vol.44 , Issue.4 , pp. 431-440
    • Solberg, I.C.1    Lygren, I.2    Jahnsen, J.3
  • 6
    • 77950889396 scopus 로고    scopus 로고
    • Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis
    • J.K.Marshall, M.Thabane, A.H.Steinhart, et al. Rectal 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst Rev. 2010;(1):CD004115.• Systematic review on the efficacy of salycilates in UC.
    • (2010) Cochrane Database Syst Rev , Issue.1 , pp. CD004115
    • Marshall, J.K.1    Thabane, M.2    Steinhart, A.H.3
  • 7
    • 0037253045 scopus 로고    scopus 로고
    • Systematic review: the pharmacokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis
    • Jan
    • W.J.Sandborn, S.B.Hanauer Systematic review: the pharmacokinetic profiles of oral mesalazine formulations and mesalazine pro-drugs used in the management of ulcerative colitis. Aliment Pharmacol Ther. 2003 Jan;17(1):29–42.
    • (2003) Aliment Pharmacol Ther , vol.17 , Issue.1 , pp. 29-42
    • Sandborn, W.J.1    Hanauer, S.B.2
  • 8
    • 33745013901 scopus 로고    scopus 로고
    • Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis
    • L.Sutherland, J.K.Macdonald. Oral 5-aminosalicylic acid for maintenance of remission in ulcerative colitis. Cochrane Database Syst Rev. 2006;(2):CD000544.• Systematic review on the efficacy of salycilates in UC.
    • (2006) Cochrane Database Syst Rev , Issue.2 , pp. CD000544
    • Sutherland, L.1    Macdonald, J.K.2
  • 9
    • 84873156311 scopus 로고    scopus 로고
    • Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis
    • B.G.Feagan, J.K.Macdonald. Oral 5-aminosalicylic acid for induction of remission in ulcerative colitis. Cochrane Database Syst Rev. 2012;10:CD000543.• Systematic review on the efficacy of salycilates in UC.
    • (2012) Cochrane Database Syst Rev , vol.10 , pp. CD000543
    • Feagan, B.G.1    Macdonald, J.K.2
  • 10
    • 33846213645 scopus 로고    scopus 로고
    • Once-daily, high-concentration MMX mesalamine in active ulcerative colitis
    • Jan, quiz 432–433
    • M.A.Kamm, W.J.Sandborn, M.Gassull, et al. Once-daily, high-concentration MMX mesalamine in active ulcerative colitis. Gastroenterology. 2007 Jan;132(1):66–75;quiz 432–433.
    • (2007) Gastroenterology , vol.132 , Issue.1 , pp. 66-75
    • Kamm, M.A.1    Sandborn, W.J.2    Gassull, M.3
  • 11
    • 58849136710 scopus 로고    scopus 로고
    • Once daily versus three times daily mesalazine granules in active ulcerative colitis: a double-blind, double-dummy, randomised, non-inferiority trial
    • Feb
    • W.Kruis, G.Kiudelis, I.Racz, et al. Once daily versus three times daily mesalazine granules in active ulcerative colitis: a double-blind, double-dummy, randomised, non-inferiority trial. Gut. 2009 Feb;58(2):233–240.•• Clinical trial that demonstrated that once-daily dosage of mesalamine is as effective as split dosage.
    • (2009) Gut , vol.58 , Issue.2 , pp. 233-240
    • Kruis, W.1    Kiudelis, G.2    Racz, I.3
  • 12
    • 80053958666 scopus 로고    scopus 로고
    • Mesalazine granules are superior to Eudragit-L-coated mesalazine tablets for induction of remission in distal ulcerative colitis - a pooled analysis
    • Nov
    • L.Leifeld, R.Pfutzer, J.Morgenstern, et al. Mesalazine granules are superior to Eudragit-L-coated mesalazine tablets for induction of remission in distal ulcerative colitis - a pooled analysis. Aliment Pharmacol Ther. 2011 Nov;34(9):1115–1122.
    • (2011) Aliment Pharmacol Ther , vol.34 , Issue.9 , pp. 1115-1122
    • Leifeld, L.1    Pfutzer, R.2    Morgenstern, J.3
  • 13
    • 84894253249 scopus 로고    scopus 로고
    • Combined oral and rectal mesalazine for the treatment of mild-to-moderately active ulcerative colitis: rapid symptom resolution and improvements in quality of life
    • Mar
    • C.S.Probert, A.U.Dignass, S.Lindgren, et al. Combined oral and rectal mesalazine for the treatment of mild-to-moderately active ulcerative colitis: rapid symptom resolution and improvements in quality of life. J Crohns Colitis. 2014 Mar;8(3):200–207.
    • (2014) J Crohns Colitis , vol.8 , Issue.3 , pp. 200-207
    • Probert, C.S.1    Dignass, A.U.2    Lindgren, S.3
  • 14
    • 21044433011 scopus 로고    scopus 로고
    • Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study
    • Jul
    • P.Marteau, C.S.Probert, S.Lindgren, et al. Combined oral and enema treatment with Pentasa (mesalazine) is superior to oral therapy alone in patients with extensive mild/moderate active ulcerative colitis: a randomised, double blind, placebo controlled study. Gut. 2005 Jul;54(7):960–965.
    • (2005) Gut , vol.54 , Issue.7 , pp. 960-965
    • Marteau, P.1    Probert, C.S.2    Lindgren, S.3
  • 15
    • 0030827118 scopus 로고    scopus 로고
    • A double-blind comparison of oral versus rectal mesalamine versus combination therapy in the treatment of distal ulcerative colitis
    • Oct
    • M.Safdi, M.DeMicco, C.Sninsky, et al. A double-blind comparison of oral versus rectal mesalamine versus combination therapy in the treatment of distal ulcerative colitis. Am J Gastroenterol. 1997 Oct;92(10):1867–1871.• Randomized clinical trial that demonstrated that combined oral and rectal treatment is more effective than oral therapy alone.
    • (1997) Am J Gastroenterol , vol.92 , Issue.10 , pp. 1867-1871
    • Safdi, M.1    DeMicco, M.2    Sninsky, C.3
  • 16
    • 0042128396 scopus 로고    scopus 로고
    • Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease
    • Jul
    • M.J.Shale, S.A.Riley. Studies of compliance with delayed-release mesalazine therapy in patients with inflammatory bowel disease. Aliment Pharmacol Ther. 2003 Jul 15;18(2):191–198.
    • (2003) Aliment Pharmacol Ther , vol.18 , Issue.2 , pp. 191-198
    • Shale, M.J.1    Riley, S.A.2
  • 18
    • 18444417417 scopus 로고    scopus 로고
    • Comparison of two different daily dosages (2.4 vs. 1.2 g) of oral mesalazine in maintenance of remission in ulcerative colitis patients: 1-year follow-up study
    • May
    • O.A.Paoluzi, F.Iacopini, R.Pica, et al. Comparison of two different daily dosages (2.4 vs. 1.2 g) of oral mesalazine in maintenance of remission in ulcerative colitis patients: 1-year follow-up study. Aliment Pharmacol Ther. 2005 May 1;21(9):1111–1119.
    • (2005) Aliment Pharmacol Ther , vol.21 , Issue.9 , pp. 1111-1119
    • Paoluzi, O.A.1    Iacopini, F.2    Pica, R.3
  • 19
    • 33748302766 scopus 로고    scopus 로고
    • Review article: high-dose aminosalicylates to induce and maintain remissions in ulcerative colitis
    • Oct
    • S.B.Hanauer. Review article: high-dose aminosalicylates to induce and maintain remissions in ulcerative colitis. Aliment Pharmacol Ther. 2006 Oct;24(Suppl 3):37–40.
    • (2006) Aliment Pharmacol Ther , vol.24 , pp. 37-40
    • Hanauer, S.B.1
  • 20
    • 34249100276 scopus 로고    scopus 로고
    • 5-Aminosalicylates and renal function in inflammatory bowel disease: a systematic review
    • May
    • J.P.Gisbert, Y.Gonzalez-Lama, J.Mate. 5-Aminosalicylates and renal function in inflammatory bowel disease: a systematic review. Inflamm Bowel Dis. 2007 May;13(5):629–638.
    • (2007) Inflamm Bowel Dis , vol.13 , Issue.5 , pp. 629-638
    • Gisbert, J.P.1    Gonzalez-Lama, Y.2    Mate, J.3
  • 21
    • 77949271455 scopus 로고    scopus 로고
    • Practice Parameters Committee of the American College of G. Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee
    • Mar, quiz 24
    • A.Kornbluth, D.B.Sachar. Practice Parameters Committee of the American College of G. Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol. 2010 Mar;105(3):501–523;quiz 24.
    • (2010) Am J Gastroenterol , vol.105 , Issue.3 , pp. 501-523
    • Kornbluth, A.1    Sachar, D.B.2
  • 22
    • 0036801121 scopus 로고    scopus 로고
    • [Individualized therapy with azathioprine or 6-mercaptopurine by monitoring thiopurine methyl-transferase (TPMT) activity]
    • Oct
    • J.P.Gisbert, F.Gomollon, J.Mate, et al. [Individualized therapy with azathioprine or 6-mercaptopurine by monitoring thiopurine methyl-transferase (TPMT) activity]. Rev Clin Esp. 2002 Oct;202(10):555–562.
    • (2002) Rev Clin Esp , vol.202 , Issue.10 , pp. 555-562
    • Gisbert, J.P.1    Gomollon, F.2    Mate, J.3
  • 23
    • 84922393995 scopus 로고    scopus 로고
    • A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia
    • Sep
    • S.K.Yang, M.Hong, J.Baek, et al. A common missense variant in NUDT15 confers susceptibility to thiopurine-induced leukopenia. Nat Genet. 2014 Sep;46(9):1017–1020.
    • (2014) Nat Genet , vol.46 , Issue.9 , pp. 1017-1020
    • Yang, S.K.1    Hong, M.2    Baek, J.3
  • 24
    • 84875979229 scopus 로고    scopus 로고
    • New genetic associations in thiopurine-related bone marrow toxicity among inflammatory bowel disease patients
    • Apr
    • W.Zabala, R.Cruz, M.Barreiro-de Acosta, et al. New genetic associations in thiopurine-related bone marrow toxicity among inflammatory bowel disease patients. Pharmacogenomics. 2013 Apr;14(6):631–640.
    • (2013) Pharmacogenomics , vol.14 , Issue.6 , pp. 631-640
    • Zabala, W.1    Cruz, R.2    Barreiro-de Acosta, M.3
  • 25
    • 21744455700 scopus 로고    scopus 로고
    • Review article: practical management of inflammatory bowel disease patients taking immunomodulators
    • Jul
    • C.A.Siegel, B.E.Sands. Review article: practical management of inflammatory bowel disease patients taking immunomodulators. Aliment Pharmacol Ther. 2005 Jul 1;22(1):1–16.
    • (2005) Aliment Pharmacol Ther , vol.22 , Issue.1 , pp. 1-16
    • Siegel, C.A.1    Sands, B.E.2
  • 26
    • 67649867062 scopus 로고    scopus 로고
    • Meta-analysis: the efficacy of azathioprine and mercaptopurine in ulcerative colitis
    • Jul
    • J.P.Gisbert, P.M.Linares, A.G.McNicholl, et al. Meta-analysis: the efficacy of azathioprine and mercaptopurine in ulcerative colitis. Aliment Pharmacol Ther. 2009 Jul 1;30(2):126–137.•• Meta-analysis on the efficacy of thiopurines in UC.
    • (2009) Aliment Pharmacol Ther , vol.30 , Issue.2 , pp. 126-137
    • Gisbert, J.P.1    Linares, P.M.2    McNicholl, A.G.3
  • 27
    • 33646011261 scopus 로고    scopus 로고
    • Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis
    • Apr
    • M.T.Osterman, R.Kundu, G.R.Lichtenstein, et al. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology. 2006 Apr;130(4):1047–1053.
    • (2006) Gastroenterology , vol.130 , Issue.4 , pp. 1047-1053
    • Osterman, M.T.1    Kundu, R.2    Lichtenstein, G.R.3
  • 28
    • 27744574836 scopus 로고    scopus 로고
    • A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn’s disease treated with azathioprine or 6-mercaptopurine
    • Oct
    • M.C.Dubinsky, E.Reyes, J.Ofman, et al. A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn’s disease treated with azathioprine or 6-mercaptopurine. Am J Gastroenterol. 2005 Oct;100(10):2239–2247.
    • (2005) Am J Gastroenterol , vol.100 , Issue.10 , pp. 2239-2247
    • Dubinsky, M.C.1    Reyes, E.2    Ofman, J.3
  • 29
    • 0034771188 scopus 로고    scopus 로고
    • Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease
    • Nov
    • P.W.Lowry, C.L.Franklin, A.L.Weaver, et al. Measurement of thiopurine methyltransferase activity and azathioprine metabolites in patients with inflammatory bowel disease. Gut. 2001 Nov;49(5):665–670.
    • (2001) Gut , vol.49 , Issue.5 , pp. 665-670
    • Lowry, P.W.1    Franklin, C.L.2    Weaver, A.L.3
  • 30
    • 10744223009 scopus 로고    scopus 로고
    • Pharmacological monitoring of azathioprine therapy
    • Sep
    • L.O.Reuther, J.Sonne, N.E.Larsen, et al. Pharmacological monitoring of azathioprine therapy. Scand J Gastroenterol. 2003 Sep;38(9):972–977.
    • (2003) Scand J Gastroenterol , vol.38 , Issue.9 , pp. 972-977
    • Reuther, L.O.1    Sonne, J.2    Larsen, N.E.3
  • 31
    • 79961209172 scopus 로고    scopus 로고
    • Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients
    • Y.Gonzalez-Lama, F.Bermejo, A.Lopez-Sanroman, et al. Thiopurine methyl-transferase activity and azathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients. Aliment Pharmacol Ther. 2011;34(5):544–554.• Study that demonstrate that zathioprine metabolite concentrations do not predict clinical outcome in thiopurine-treated inflammatory bowel disease patients.
    • (2011) Aliment Pharmacol Ther , vol.34 , Issue.5 , pp. 544-554
    • Gonzalez-Lama, Y.1    Bermejo, F.2    Lopez-Sanroman, A.3
  • 32
    • 67650416300 scopus 로고    scopus 로고
    • Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn’s disease
    • E.Prefontaine, L.R.Sutherland, J.K.Macdonald, et al. Azathioprine or 6-mercaptopurine for maintenance of remission in Crohn’s disease. Cochrane Database Syst Rev. 2009;(1):CD000067.
    • (2009) Cochrane Database Syst Rev , Issue.1 , pp. CD000067
    • Prefontaine, E.1    Sutherland, L.R.2    Macdonald, J.K.3
  • 33
    • 84879102390 scopus 로고    scopus 로고
    • Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients
    • Jun
    • M.Chaparro, I.Ordas, E.Cabre, et al. Safety of thiopurine therapy in inflammatory bowel disease: long-term follow-up study of 3931 patients. Inflamm Bowel Dis. 2013 Jun;19(7):1404–1410.
    • (2013) Inflamm Bowel Dis , vol.19 , Issue.7 , pp. 1404-1410
    • Chaparro, M.1    Ordas, I.2    Cabre, E.3
  • 34
    • 50649110056 scopus 로고    scopus 로고
    • Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: a review
    • Jul
    • J.P.Gisbert, F.Gomollon. Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: a review. Am J Gastroenterol. 2008 Jul;103(7):1783–1800.
    • (2008) Am J Gastroenterol , vol.103 , Issue.7 , pp. 1783-1800
    • Gisbert, J.P.1    Gomollon, F.2
  • 35
    • 34250797604 scopus 로고    scopus 로고
    • Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review
    • Jul
    • J.P.Gisbert, Y.Gonzalez-Lama, J.Mate. Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review. Am J Gastroenterol. 2007 Jul;102(7):1518–1527.
    • (2007) Am J Gastroenterol , vol.102 , Issue.7 , pp. 1518-1527
    • Gisbert, J.P.1    Gonzalez-Lama, Y.2    Mate, J.3
  • 36
    • 22644446331 scopus 로고    scopus 로고
    • Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine
    • A.Kandiel, A.G.Fraser, B.I.Korelitz, et al. Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut. 2005;54(8):1121–1125.•• Study that suggested that there was an increased risk of lymphoma in IBD patients treated with thiopurines.
    • (2005) Gut , vol.54 , Issue.8 , pp. 1121-1125
    • Kandiel, A.1    Fraser, A.G.2    Korelitz, B.I.3
  • 37
    • 70449100743 scopus 로고    scopus 로고
    • Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
    • Nov
    • L.Beaugerie, N.Brousse, A.M.Bouvier, et al. Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet. 2009 Nov 7;374(9701):1617–1625.•• Study that suggested that there was an increased risk of lymphoma in IBD patients treated with thiopurines.
    • (2009) Lancet , vol.374 , Issue.9701 , pp. 1617-1625
    • Beaugerie, L.1    Brousse, N.2    Bouvier, A.M.3
  • 38
    • 84927722749 scopus 로고    scopus 로고
    • Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis
    • quiz e48–50
    • D.S.Kotlyar, J.D.Lewis, L.Beaugerie, et al. Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis. Clin Gastroenterol Hepatol. 2015;13(5):847–850;quiz e48–50.
    • (2015) Clin Gastroenterol Hepatol , vol.13 , Issue.5 , pp. 847-850
    • Kotlyar, D.S.1    Lewis, J.D.2    Beaugerie, L.3
  • 39
    • 77957836758 scopus 로고    scopus 로고
    • Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality
    • Oct
    • D.S.Kotlyar, W.Blonski, R.H.Diamond, et al. Hepatosplenic T-cell lymphoma in inflammatory bowel disease: a possible thiopurine-induced chromosomal abnormality. Am J Gastroenterol. 2010 Oct;105(10):2299–2301.
    • (2010) Am J Gastroenterol , vol.105 , Issue.10 , pp. 2299-2301
    • Kotlyar, D.S.1    Blonski, W.2    Diamond, R.H.3
  • 40
    • 84893772239 scopus 로고    scopus 로고
    • Association between thiopurine use and nonmelanoma skin cancers in patients with inflammatory bowel disease: a meta-analysis
    • Feb
    • J.Ariyaratnam, V.Subramanian. Association between thiopurine use and nonmelanoma skin cancers in patients with inflammatory bowel disease: a meta-analysis. Am J Gastroenterol. 2014 Feb;109(2):163–169.
    • (2014) Am J Gastroenterol , vol.109 , Issue.2 , pp. 163-169
    • Ariyaratnam, J.1    Subramanian, V.2
  • 41
    • 25444502974 scopus 로고    scopus 로고
    • Autoimmunity and anti-TNF-alpha agents
    • F.Atzeni, M.Turiel, F.Capsoni, et al. Autoimmunity and anti-TNF-alpha agents. Ann N Y Acad Sci. 2005;1051:559–569.
    • (2005) Ann N Y Acad Sci , vol.1051 , pp. 559-569
    • Atzeni, F.1    Turiel, M.2    Capsoni, F.3
  • 42
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction and maintenance therapy for ulcerative colitis
    • Dec
    • P.Rutgeerts, W.J.Sandborn, B.G.Feagan, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med. 2005 Dec 8;353(23):2462–2476.
    • (2005) N Engl J Med , vol.353 , Issue.23 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 43
    • 70349418632 scopus 로고    scopus 로고
    • Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab
    • quiz 520
    • W.J.Sandborn, P.Rutgeerts, B.G.Feagan, et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology. 2009;137(4):1250–1260;quiz 520.•• Post-hoc analysis of the ACT-1 and 2 trials assessing the impact of infliximab on the need of colectomy in UC patients.
    • (2009) Gastroenterology , vol.137 , Issue.4 , pp. 1250-1260
    • Sandborn, W.J.1    Rutgeerts, P.2    Feagan, B.G.3
  • 44
    • 84870293844 scopus 로고    scopus 로고
    • Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial
    • Dec
    • D.Laharie, A.Bourreille, J.Branche, et al. Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial. Lancet. 2012 Dec 1;380(9857):1909–1915.
    • (2012) Lancet , vol.380 , Issue.9857 , pp. 1909-1915
    • Laharie, D.1    Bourreille, A.2    Branche, J.3
  • 45
    • 83855165079 scopus 로고    scopus 로고
    • Infliximab salvage therapy after failure of ciclosporin in corticosteroid-refractory ulcerative colitis: a multicentre study
    • Jan
    • M.Chaparro, P.Burgueno, E.Iglesias, et al. Infliximab salvage therapy after failure of ciclosporin in corticosteroid-refractory ulcerative colitis: a multicentre study. Aliment Pharmacol Ther. 2012 Jan;35(2):275–283.
    • (2012) Aliment Pharmacol Ther , vol.35 , Issue.2 , pp. 275-283
    • Chaparro, M.1    Burgueno, P.2    Iglesias, E.3
  • 46
    • 65549113070 scopus 로고    scopus 로고
    • Infliximab rescue therapy after cyclosporin failure in steroid-refractory ulcerative colitis
    • M.Manosa, A.Lopez San Roman, E.Garcia-Planella, et al. Infliximab rescue therapy after cyclosporin failure in steroid-refractory ulcerative colitis. Digestion. 2009;80(1):30–35.
    • (2009) Digestion , vol.80 , Issue.1 , pp. 30-35
    • Manosa, M.1    Lopez San Roman, A.2    Garcia-Planella, E.3
  • 47
    • 85020318416 scopus 로고    scopus 로고
    • Efficacy and safety of the biosimilar infliximab CT-P13 treatment in inflammatory bowel diseases: a prospective, multicentre, nationwide cohort
    • Feb
    • K.B.Gecse, B.D.Lovasz, K.Farkas, et al. Efficacy and safety of the biosimilar infliximab CT-P13 treatment in inflammatory bowel diseases: a prospective, multicentre, nationwide cohort. J Crohns Colitis. 2016 Feb;10(2):133–140.
    • (2016) J Crohns Colitis , vol.10 , Issue.2 , pp. 133-140
    • Gecse, K.B.1    Lovasz, B.D.2    Farkas, K.3
  • 48
    • 84942303588 scopus 로고    scopus 로고
    • Biosimilar infliximab (CT-P13) in the treatment of inflammatory bowel disease: a Norwegian observational study
    • J.Jahnsen, T.E.Detlie, S.Vatn, et al. Biosimilar infliximab (CT-P13) in the treatment of inflammatory bowel disease: a Norwegian observational study. Expert Rev Gastroenterol Hepatol. 2015;9(Suppl 1):45–52.
    • (2015) Expert Rev Gastroenterol Hepatol , vol.9 , pp. 45-52
    • Jahnsen, J.1    Detlie, T.E.2    Vatn, S.3
  • 49
    • 84942325078 scopus 로고    scopus 로고
    • Post-marketing study of biosimilar infliximab (CT-P13) to evaluate its safety and efficacy in Korea
    • S.H.Park, Y.H.Kim, J.H.Lee, et al. Post-marketing study of biosimilar infliximab (CT-P13) to evaluate its safety and efficacy in Korea. Expert Rev Gastroenterol Hepatol. 2015;9(Suppl 1):35–44.
    • (2015) Expert Rev Gastroenterol Hepatol , vol.9 , pp. 35-44
    • Park, S.H.1    Kim, Y.H.2    Lee, J.H.3
  • 50
    • 0037018761 scopus 로고    scopus 로고
    • Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial
    • May
    • S.B.Hanauer, B.G.Feagan, G.R.Lichtenstein, et al. Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial. Lancet. 2002 May 4;359(9317):1541–1549.
    • (2002) Lancet , vol.359 , Issue.9317 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 51
    • 10744221312 scopus 로고    scopus 로고
    • Infliximab maintenance therapy for fistulizing Crohn’s disease
    • Feb
    • B.E.Sands, F.H.Anderson, C.N.Bernstein, et al. Infliximab maintenance therapy for fistulizing Crohn’s disease. N Engl J Med. 2004 Feb 26;350(9):876–885.
    • (2004) N Engl J Med , vol.350 , Issue.9 , pp. 876-885
    • Sands, B.E.1    Anderson, F.H.2    Bernstein, C.N.3
  • 52
    • 84892737455 scopus 로고    scopus 로고
    • Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis
    • Feb
    • R.Panaccione, S.Ghosh, S.Middleton, et al. Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis. Gastroenterology. 2014 Feb;146(2):392–400e3.• Study that demonstrated that combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in UC.
    • (2014) Gastroenterology , vol.146 , Issue.2 , pp. 392-400e3
    • Panaccione, R.1    Ghosh, S.2    Middleton, S.3
  • 53
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn’s disease: a review
    • Mar
    • J.P.Gisbert, J.Panes. Loss of response and requirement of infliximab dose intensification in Crohn’s disease: a review. Am J Gastroenterol. 2009 Mar;104(3):760–767.
    • (2009) Am J Gastroenterol , vol.104 , Issue.3 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 54
    • 84875725735 scopus 로고    scopus 로고
    • Systematic review: antibodies and anti-TNF-alpha levels in inflammatory bowel disease
    • May
    • M.Chaparro, I.Guerra, P.Munoz-Linares, et al. Systematic review: antibodies and anti-TNF-alpha levels in inflammatory bowel disease. Aliment Pharmacol Ther. 2012 May;35(9):971–986.
    • (2012) Aliment Pharmacol Ther , vol.35 , Issue.9 , pp. 971-986
    • Chaparro, M.1    Guerra, I.2    Munoz-Linares, P.3
  • 55
    • 78651237721 scopus 로고    scopus 로고
    • The immunogenic part of infliximab is the F(ab’)2, but measuring antibodies to the intact infliximab molecule is more clinically useful
    • Jan
    • S.Ben-Horin, M.Yavzori, L.Katz, et al. The immunogenic part of infliximab is the F(ab’)2, but measuring antibodies to the intact infliximab molecule is more clinically useful. Gut. 2011 Jan;60(1):41–48.
    • (2011) Gut , vol.60 , Issue.1 , pp. 41-48
    • Ben-Horin, S.1    Yavzori, M.2    Katz, L.3
  • 56
    • 79953801792 scopus 로고    scopus 로고
    • Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis
    • quiz 60
    • A.C.Ford, W.J.Sandborn, K.J.Khan, et al. Efficacy of biological therapies in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol. 2011;106(4):644–659;quiz 60.
    • (2011) Am J Gastroenterol , vol.106 , Issue.4 , pp. 644-659
    • Ford, A.C.1    Sandborn, W.J.2    Khan, K.J.3
  • 57
    • 2642554059 scopus 로고    scopus 로고
    • Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients
    • Jun
    • F.Wolfe, K.Michaud. Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients. Arthritis Rheum. 2004 Jun;50(6):1740–1751.
    • (2004) Arthritis Rheum , vol.50 , Issue.6 , pp. 1740-1751
    • Wolfe, F.1    Michaud, K.2
  • 58
    • 84860836594 scopus 로고    scopus 로고
    • Fistulizing pattern in Crohn’s disease and pancolitis in ulcerative colitis are independent risk factors for cancer: a single-center cohort study
    • Jun
    • L.Biancone, S.Zuzzi, M.Ranieri, et al. Fistulizing pattern in Crohn’s disease and pancolitis in ulcerative colitis are independent risk factors for cancer: a single-center cohort study. J Crohns Colitis. 2012 Jun;6(5):578–587.
    • (2012) J Crohns Colitis , vol.6 , Issue.5 , pp. 578-587
    • Biancone, L.1    Zuzzi, S.2    Ranieri, M.3
  • 59
    • 84946914743 scopus 로고    scopus 로고
    • Risk of lymphoma, colorectal and skin cancer in patients with IBD treated with immunomodulators and biologics: a quebec claims database study
    • Aug
    • U.Kopylov, M.Vutcovici, A.Kezouh, et al. Risk of lymphoma, colorectal and skin cancer in patients with IBD treated with immunomodulators and biologics: a quebec claims database study. Inflamm Bowel Dis. 2015 Aug;21(8):1847–1853.
    • (2015) Inflamm Bowel Dis , vol.21 , Issue.8 , pp. 1847-1853
    • Kopylov, U.1    Vutcovici, M.2    Kezouh, A.3
  • 60
    • 79955859430 scopus 로고    scopus 로고
    • Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial
    • Jun
    • W.Reinisch, W.J.Sandborn, D.W.Hommes, et al. Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut. 2011 Jun;60(6):780–787.
    • (2011) Gut , vol.60 , Issue.6 , pp. 780-787
    • Reinisch, W.1    Sandborn, W.J.2    Hommes, D.W.3
  • 61
    • 84856163835 scopus 로고    scopus 로고
    • Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis
    • Feb e1–3
    • W.J.Sandborn, G.van Assche, W.Reinisch, et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology. 2012 Feb;142(2):257–265e1–3.
    • (2012) Gastroenterology , vol.142 , Issue.2 , pp. 257-265
    • Sandborn, W.J.1    van Assche, G.2    Reinisch, W.3
  • 62
    • 84908890256 scopus 로고    scopus 로고
    • Four-year maintenance treatment with adalimumab in patients with moderately to severely active ulcerative colitis: data from ULTRA 1, 2, and 3
    • Nov
    • J.F.Colombel, W.J.Sandborn, S.Ghosh, et al. Four-year maintenance treatment with adalimumab in patients with moderately to severely active ulcerative colitis: data from ULTRA 1, 2, and 3. Am J Gastroenterol. 2014 Nov;109(11):1771–1780.
    • (2014) Am J Gastroenterol , vol.109 , Issue.11 , pp. 1771-1780
    • Colombel, J.F.1    Sandborn, W.J.2    Ghosh, S.3
  • 63
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn’s disease: the CLASSIC-I trial
    • Feb, quiz 591
    • S.B.Hanauer, W.J.Sandborn, P.Rutgeerts, et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn’s disease: the CLASSIC-I trial. Gastroenterology. 2006 Feb;130(2):323–333;quiz 591.
    • (2006) Gastroenterology , vol.130 , Issue.2 , pp. 323-333
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 64
    • 84890688226 scopus 로고    scopus 로고
    • Adalimumab therapy is associated with reduced risk of hospitalization in patients with ulcerative colitis
    • Jan
    • B.G.Feagan, W.J.Sandborn, A.Lazar, et al. Adalimumab therapy is associated with reduced risk of hospitalization in patients with ulcerative colitis. Gastroenterology. 2014 Jan;146(1):110–18e3.
    • (2014) Gastroenterology , vol.146 , Issue.1 , pp. 110-18e3
    • Feagan, B.G.1    Sandborn, W.J.2    Lazar, A.3
  • 65
    • 52149104260 scopus 로고    scopus 로고
    • Long-term outcome of adalimumab therapy for ulcerative colitis with intolerance or lost response to infliximab: a single-centre experience
    • Oct
    • A.Oussalah, C.Laclotte, J.B.Chevaux, et al. Long-term outcome of adalimumab therapy for ulcerative colitis with intolerance or lost response to infliximab: a single-centre experience. Aliment Pharmacol Ther. 2008 Oct 15;28(8):966–972.
    • (2008) Aliment Pharmacol Ther , vol.28 , Issue.8 , pp. 966-972
    • Oussalah, A.1    Laclotte, C.2    Chevaux, J.B.3
  • 66
    • 70449727863 scopus 로고    scopus 로고
    • Open-label study of adalimumab in patients with ulcerative colitis including those with prior loss of response or intolerance to infliximab
    • Sep
    • W.Afif, J.A.Leighton, S.B.Hanauer, et al. Open-label study of adalimumab in patients with ulcerative colitis including those with prior loss of response or intolerance to infliximab. Inflamm Bowel Dis. 2009 Sep;15(9):1302–1307.
    • (2009) Inflamm Bowel Dis , vol.15 , Issue.9 , pp. 1302-1307
    • Afif, W.1    Leighton, J.A.2    Hanauer, S.B.3
  • 67
    • 77954752112 scopus 로고    scopus 로고
    • Treatment of ulcerative colitis with adalimumab or infliximab: long-term follow-up of a single-centre cohort
    • Aug
    • N.Gies, K.I.Kroeker, K.Wong, et al. Treatment of ulcerative colitis with adalimumab or infliximab: long-term follow-up of a single-centre cohort. Aliment Pharmacol Ther. 2010 Aug;32(4):522–528.
    • (2010) Aliment Pharmacol Ther , vol.32 , Issue.4 , pp. 522-528
    • Gies, N.1    Kroeker, K.I.2    Wong, K.3
  • 68
    • 78650892656 scopus 로고    scopus 로고
    • Adalimumab induction and maintenance therapy for patients with ulcerative colitis previously treated with infliximab
    • Feb
    • C.Taxonera, J.Estelles, I.Fernandez-Blanco, et al. Adalimumab induction and maintenance therapy for patients with ulcerative colitis previously treated with infliximab. Aliment Pharmacol Ther. 2011 Feb;33(3):340–348.
    • (2011) Aliment Pharmacol Ther , vol.33 , Issue.3 , pp. 340-348
    • Taxonera, C.1    Estelles, J.2    Fernandez-Blanco, I.3
  • 69
    • 84872497210 scopus 로고    scopus 로고
    • Efficacy of adalimumab as a long term maintenance therapy in ulcerative colitis
    • Mar
    • E.McDermott, S.Murphy, D.Keegan, et al. Efficacy of adalimumab as a long term maintenance therapy in ulcerative colitis. J Crohns Colitis. 2013 Mar;7(2):150–153.
    • (2013) J Crohns Colitis , vol.7 , Issue.2 , pp. 150-153
    • McDermott, E.1    Murphy, S.2    Keegan, D.3
  • 70
    • 84881542095 scopus 로고    scopus 로고
    • Observational study on the efficacy of adalimumab for the treatment of ulcerative colitis and predictors of outcome
    • Oct
    • O.Garcia-Bosch, J.P.Gisbert, A.Canas-Ventura, et al. Observational study on the efficacy of adalimumab for the treatment of ulcerative colitis and predictors of outcome. J Crohns Colitis. 2013 Oct;7(9):717–722.
    • (2013) J Crohns Colitis , vol.7 , Issue.9 , pp. 717-722
    • Garcia-Bosch, O.1    Gisbert, J.P.2    Canas-Ventura, A.3
  • 71
    • 84876046983 scopus 로고    scopus 로고
    • Adalimumab in active ulcerative colitis: a “real-life” observational study
    • Sep
    • Italian Group for the Study of Inflammatory, D.Bowel, A.Armuzzi, L.Biancone, et al. Adalimumab in active ulcerative colitis: a “real-life” observational study. Dig Liver Dis. 2013 Sep;45(9):738–743.
    • (2013) Dig Liver Dis , vol.45 , Issue.9 , pp. 738-743
    • Bowel, D.1    Armuzzi, A.2    Biancone, L.3
  • 72
    • 49249123639 scopus 로고    scopus 로고
    • Golimumab, a fully human monoclonal antibody against TNFalpha
    • Aug
    • G.Hutas. Golimumab, a fully human monoclonal antibody against TNFalpha. Curr Opin Mol Ther. 2008 Aug;10(4):393–406.
    • (2008) Curr Opin Mol Ther , vol.10 , Issue.4 , pp. 393-406
    • Hutas, G.1
  • 73
    • 27144532832 scopus 로고    scopus 로고
    • Human antibodies from transgenic animals
    • Sep
    • N.Lonberg. Human antibodies from transgenic animals. Nat Biotechnol. 2005 Sep;23(9):1117–1125.
    • (2005) Nat Biotechnol , vol.23 , Issue.9 , pp. 1117-1125
    • Lonberg, N.1
  • 74
    • 77958520182 scopus 로고    scopus 로고
    • Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor alpha
    • Jul-Aug
    • D.J.Shealy, A.Cai, K.Staquet, et al. Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor alpha. mAbs. 2010 Jul-Aug;2(4):428–439.
    • (2010) mAbs , vol.2 , Issue.4 , pp. 428-439
    • Shealy, D.J.1    Cai, A.2    Staquet, K.3
  • 75
    • 84890620601 scopus 로고    scopus 로고
    • Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis
    • Jan, quiz e14–e15
    • W.J.Sandborn, B.G.Feagan, C.Marano, et al. Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology. 2014 Jan;146(1):85–95;quiz e14–e15.
    • (2014) Gastroenterology , vol.146 , Issue.1 , pp. 85-95
    • Sandborn, W.J.1    Feagan, B.G.2    Marano, C.3
  • 76
    • 84890629055 scopus 로고    scopus 로고
    • Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis
    • Jan
    • W.J.Sandborn, B.G.Feagan, C.Marano, et al. Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis. Gastroenterology. 2014 Jan;146(1):96–109e1.
    • (2014) Gastroenterology , vol.146 , Issue.1 , pp. 96-109e1
    • Sandborn, W.J.1    Feagan, B.G.2    Marano, C.3
  • 77
    • 0035047362 scopus 로고    scopus 로고
    • LDP-02 (Millenium)
    • Apr
    • J.K.Marshall. LDP-02 (Millenium). Curr Opin Invest Drugs. 2001 Apr;2(4):502–504.
    • (2001) Curr Opin Invest Drugs , vol.2 , Issue.4 , pp. 502-504
    • Marshall, J.K.1
  • 78
    • 0029670925 scopus 로고    scopus 로고
    • Alpha 4 integrin plays a critical role in early stages of T lymphocyte migration in Peyer’s patches of rats
    • Mar
    • Y.Tsuzuki, S.Miura, M.Suematsu, et al. Alpha 4 integrin plays a critical role in early stages of T lymphocyte migration in Peyer’s patches of rats. Int Immunol. 1996 Mar;8(3):287–295.
    • (1996) Int Immunol , vol.8 , Issue.3 , pp. 287-295
    • Tsuzuki, Y.1    Miura, S.2    Suematsu, M.3
  • 79
    • 78650316496 scopus 로고    scopus 로고
    • Vedolizumab, a humanized mAb against the alpha4beta7 integrin for the potential treatment of ulcerative colitis and Crohn’s disease
    • Nov
    • H.Tilg, A.Kaser. Vedolizumab, a humanized mAb against the alpha4beta7 integrin for the potential treatment of ulcerative colitis and Crohn’s disease. Curr Opin Invest Drugs. 2010 Nov;11(11):1295–1304.
    • (2010) Curr Opin Invest Drugs , vol.11 , Issue.11 , pp. 1295-1304
    • Tilg, H.1    Kaser, A.2
  • 80
    • 0032733508 scopus 로고    scopus 로고
    • Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease
    • Dec
    • H.S.Souza, C.C.Elia, J.Spencer, et al. Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease. Gut. 1999 Dec;45(6):856–863.
    • (1999) Gut , vol.45 , Issue.6 , pp. 856-863
    • Souza, H.S.1    Elia, C.C.2    Spencer, J.3
  • 81
    • 84882769357 scopus 로고    scopus 로고
    • Vedolizumab as induction and maintenance therapy for ulcerative colitis
    • Aug
    • B.G.Feagan, P.Rutgeerts, B.E.Sands, et al. Vedolizumab as induction and maintenance therapy for ulcerative colitis. N Engl J Med. 2013 Aug 22;369(8):699–710.•• Randomized clinical trial on the efficacy of vedolizumab in UC.
    • (2013) N Engl J Med , vol.369 , Issue.8 , pp. 699-710
    • Feagan, B.G.1    Rutgeerts, P.2    Sands, B.E.3
  • 82
    • 84986574786 scopus 로고    scopus 로고
    • Long-term efficacy of vedolizumab therapy for Crohn’s disease
    • H.Hanauer, P.Rutgeerts, J.Xu, et al. Long-term efficacy of vedolizumab therapy for Crohn’s disease. United Eur Gastroenterol J. 2014;2014(2):A66.
    • (2014) United Eur Gastroenterol J , vol.2014 , Issue.2 , pp. A66
    • Hanauer, H.1    Rutgeerts, P.2    Xu, J.3
  • 83
    • 84882749768 scopus 로고    scopus 로고
    • Vedolizumab as induction and maintenance therapy for Crohn’s disease
    • Aug
    • W.J.Sandborn, B.G.Feagan, P.Rutgeerts, et al. Vedolizumab as induction and maintenance therapy for Crohn’s disease. N Engl J Med. 2013 Aug 22;369(8):711–721.
    • (2013) N Engl J Med , vol.369 , Issue.8 , pp. 711-721
    • Sandborn, W.J.1    Feagan, B.G.2    Rutgeerts, P.3
  • 84
    • 84879443839 scopus 로고    scopus 로고
    • Vedolizumab induction therapy for patients with Crohn’s disease and prior anti-tumour necrosis factor antagonist failure: a randomised placebo-controlled, double-blind, multicenter trial
    • B.E.Sands, B.G.Feagan, P.Rutgeerts, et al. Vedolizumab induction therapy for patients with Crohn’s disease and prior anti-tumour necrosis factor antagonist failure: a randomised placebo-controlled, double-blind, multicenter trial. J Crohns Colitis. 2013;7(Suppl. 1):S5–S6.
    • (2013) J Crohns Colitis , vol.7 , pp. S5-S6
    • Sands, B.E.1    Feagan, B.G.2    Rutgeerts, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.