메뉴 건너뛰기




Volumn 21, Issue , 2015, Pages 769-781

Genome-wide association study of late-onset myasthenia gravis: Confirmation of TNFRSF11A and identification of ZBTB10 and three distinct HLA associations

(19)  Seldin, Michael F a   Alkhairy, Omar K b   Lee, Annette T c   Lamb, Janine A d   Sussman, Jon e   Pirskanen Matell, Ritva b   Piehl, Fredrik b   Verschuuren, Jan J G M f   Kostera Pruszczyk, Anna g   Szczudlik, Piotr g   McKee, David e   Maniaol, Angelina H h   Harbo, Hanne F i   Lie, Benedicte A i   Melms, Arthur j,k   Garchon, Henri Jean l   Willcox, Nicholas m   Gregersen, Peter K c   Hammarstrom, Lennart b  


Author keywords

[No Author keywords available]

Indexed keywords

CHOLINERGIC RECEPTOR ANTIBODY; HLA A ANTIGEN; HLA ANTIGEN; HLA DQA1 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 3; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B;

EID: 84975152216     PISSN: 10761551     EISSN: 15283658     Source Type: Journal    
DOI: 10.2119/molmed.2015.00232     Document Type: Article
Times cited : (51)

References (65)
  • 1
    • 75549086673 scopus 로고    scopus 로고
    • The incidence of myasthenia gravis: A systematic literature review
    • McGrogan A, Sneddon S, de Vries CS. (2010) The incidence of myasthenia gravis: a systematic literature review. Neuroepidemiology. 34:171-83.
    • (2010) Neuroepidemiology , vol.34 , pp. 171-183
    • McGrogan, A.1    Sneddon, S.2    De Vries, C.S.3
  • 2
    • 64349115066 scopus 로고    scopus 로고
    • Autoimmune myasthenia gravis: Emerging clinical and biological heterogeneity
    • Meriggioli MN, Sanders DB. (2009) Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity. Lancet. 8:475-90.
    • (2009) Lancet , vol.8 , pp. 475-490
    • Meriggioli, M.N.1    Sanders, D.B.2
  • 3
    • 77953633370 scopus 로고    scopus 로고
    • A systematic review of population based epidemiological studies in Myasthenia Gravis
    • Carr AS, Cardwell CR, McCarron PO, McConville J. (2010) A systematic review of population based epidemiological studies in Myasthenia Gravis. BMC Neurol. 10:46.
    • (2010) BMC Neurol , vol.10 , pp. 46
    • Carr, A.S.1    Cardwell, C.R.2    McCarron, P.O.3    McConville, J.4
  • 5
    • 84904289646 scopus 로고    scopus 로고
    • Late-onset myasthenia gravis-CTLA4(Low) genotype association and low-for-age thymic output of naive T cells
    • Chuang WY, et al. (2014) Late-onset myasthenia gravis-CTLA4(low) genotype association and low-for-age thymic output of naive T cells. J. Autoimmun. 52:122-9.
    • (2014) J. Autoimmun , vol.52 , pp. 122-129
    • Chuang, W.Y.1
  • 6
    • 84860727608 scopus 로고    scopus 로고
    • Late onset myasthenia gravis is associated with HLA DRB1*15:01 in the Norwegian population
    • Maniaol AH, et al. (2012) Late onset myasthenia gravis is associated with HLA DRB1*15:01 in the Norwegian population. PLoS One. 7:e36603.
    • (2012) Plos One , vol.7
    • Maniaol, A.H.1
  • 7
    • 0018943586 scopus 로고
    • Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis
    • Compston DA, Vincent A, Newsom-Davis J, Batchelor JR. (1980) Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis. Brain. 103:579-601.
    • (1980) Brain , vol.103 , pp. 579-601
    • Compston, D.A.1    Vincent, A.2    Newsom-Davis, J.3    Batchelor, J.R.4
  • 9
    • 84906991505 scopus 로고    scopus 로고
    • Insights into the classification of myasthenia gravis
    • Akaishi T, et al. (2014) Insights into the classification of myasthenia gravis. PLoS One. 9:e106757.
    • (2014) Plos One , vol.9
    • Akaishi, T.1
  • 10
    • 0032879076 scopus 로고    scopus 로고
    • A susceptibility region for myasthenia gravis extending into the HLA-class I sector telomeric to HLA-C
    • Janer M, et al. (1999) A susceptibility region for myasthenia gravis extending into the HLA-class I sector telomeric to HLA-C. Hum. Immunol. 60:909-17.
    • (1999) Hum. Immunol , vol.60 , pp. 909-917
    • Janer, M.1
  • 11
    • 84904365931 scopus 로고    scopus 로고
    • Genetic basis of myasthenia gravis: A comprehensive review
    • Avidan N, Le Panse R, Berrih-Aknin S, Miller A. (2014) Genetic basis of myasthenia gravis: a comprehensive review. J. Autoimmun. 52:146-53.
    • (2014) J. Autoimmun , vol.52 , pp. 146-153
    • Avidan, N.1    Le Panse, R.2    Berrih-Aknin, S.3    Miller, A.4
  • 12
    • 0035856431 scopus 로고    scopus 로고
    • Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodies
    • Giraud M, et al. (2001) Linkage of HLA to myasthenia gravis and genetic heterogeneity depending on anti-titin antibodies. Neurology. 57:1555-60.
    • (2001) Neurology , vol.57 , pp. 1555-1560
    • Giraud, M.1
  • 14
    • 32044456473 scopus 로고    scopus 로고
    • Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis
    • Vandiedonck C, et al. (2006) Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis. Ann. Neurol. 59:404-7.
    • (2006) Ann. Neurol , vol.59 , pp. 404-407
    • Vandiedonck, C.1
  • 15
    • 84871950028 scopus 로고    scopus 로고
    • Risk for myasthenia gravis maps to a (151) Pro—>Ala change in TNIP1 and to human leukocyte antigen-B*08
    • Gregersen PK, et al. (2012) Risk for myasthenia gravis maps to a (151) Pro—>Ala change in TNIP1 and to human leukocyte antigen-B*08. Ann Neurol 72:927-935.
    • (2012) Ann Neurol , vol.72 , pp. 927-935
    • Gregersen, P.K.1
  • 16
    • 84928142532 scopus 로고    scopus 로고
    • A genome-wide association study of myasthenia gravis
    • Renton AE, et al. (2015) A genome-wide association study of myasthenia gravis. JAMA Neurol. 72:396-404.
    • (2015) JAMA Neurol , vol.72 , pp. 396-404
    • Renton, A.E.1
  • 17
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: A tool set for whole-genome association and population-based linkage analyses
    • Purcell S, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am. J. Hum. Genet. 81:559-75.
    • (2007) Am. J. Hum. Genet , vol.81 , pp. 559-575
    • Purcell, S.1
  • 18
    • 0034118493 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data
    • Pritchard JK, Stephens M, Donnelly P. (2000) Inference of population structure using multilocus genotype data. Genetics. 155:945-59.
    • (2000) Genetics , vol.155 , pp. 945-959
    • Pritchard, J.K.1    Stephens, M.2    Donnelly, P.3
  • 19
    • 0041817568 scopus 로고    scopus 로고
    • Inference of population structure using multilocus genotype data: Linked loci and correlated allele frequencies
    • Falush D, Stephens M, Pritchard JK. (2003) Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics. 164:1567-87.
    • (2003) Genetics , vol.164 , pp. 1567-1587
    • Falush, D.1    Stephens, M.2    Pritchard, J.K.3
  • 20
    • 58349108089 scopus 로고    scopus 로고
    • Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America
    • Kosoy R, et al. (2009) Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America. Hum. Mutat. 30:69-78.
    • (2009) Hum. Mutat , vol.30 , pp. 69-78
    • Kosoy, R.1
  • 21
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet. 38:904-9.
    • (2006) Nat. Genet , vol.38 , pp. 904-909
    • Price, A.L.1
  • 22
    • 84901370399 scopus 로고    scopus 로고
    • A general approach for haplotype phasing across the full spectrum of relatedness
    • O’Connell J, et al. (2014) A general approach for haplotype phasing across the full spectrum of relatedness. PLoS Genet. 10:e1004234.
    • (2014) Plos Genet , vol.10
    • O’Connell, J.1
  • 24
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie BN, Donnelly P, Marchini J. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet. 5:e1000529.
    • (2009) Plos Genet , vol.5
    • Howie, B.N.1    Donnelly, P.2    Marchini, J.3
  • 25
    • 84878802935 scopus 로고    scopus 로고
    • Imputing amino acid polymorphisms in human leukocyte antigens
    • Jia X, et al. (2013) Imputing amino acid polymorphisms in human leukocyte antigens. PLoS One. 8:e64683.
    • (2013) Plos One , vol.8
    • Jia, X.1
  • 26
    • 62649155943 scopus 로고    scopus 로고
    • A unified approach to genotype imputation and haplotypephase inference for large data sets of trios and unrelated individuals
    • Browning BL, Browning SR. (2009) A unified approach to genotype imputation and haplotypephase inference for large data sets of trios and unrelated individuals. Am. J. Hum. Genet. 84:210-23.
    • (2009) Am. J. Hum. Genet , vol.84 , pp. 210-223
    • Browning, B.L.1    Browning, S.R.2
  • 27
    • 84865712382 scopus 로고    scopus 로고
    • Annotation of functional variation in personal genomes using RegulomeDB
    • Boyle AP, et al. (2012) Annotation of functional variation in personal genomes using RegulomeDB. Genome Res. 22:1790-7.
    • (2012) Genome Res , vol.22 , pp. 1790-1797
    • Boyle, A.P.1
  • 28
    • 77956586071 scopus 로고    scopus 로고
    • LocusZoom: Regional visualization of genome-wide association scan results
    • Pruim RJ, et al. (2010) LocusZoom: regional visualization of genome-wide association scan results. Bioinformatics. 26:2336-7.
    • (2010) Bioinformatics , vol.26 , pp. 2336-2337
    • Pruim, R.J.1
  • 29
    • 84857111200 scopus 로고    scopus 로고
    • DNase I sensitivity QTLs are a major determinant of human expression variation
    • Degner JF, et al. (2012) DNase I sensitivity QTLs are a major determinant of human expression variation. Nature. 482:390-4.
    • (2012) Nature , vol.482 , pp. 390-394
    • Degner, J.F.1
  • 30
    • 84864619335 scopus 로고    scopus 로고
    • A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation
    • Coviello AD, et al. (2012) A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet. 8:e1002805.
    • (2012) Plos Genet , vol.8
    • Coviello, A.D.1
  • 31
    • 84901754015 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype
    • Ferreira MA, et al. (2014) Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype. J. Allergy Clin. Immunol. 133:1564-71.
    • (2014) J. Allergy Clin. Immunol , vol.133 , pp. 1564-1571
    • Ferreira, M.A.1
  • 32
    • 84859506990 scopus 로고    scopus 로고
    • Novel associations for hypothyroidism include known autoimmune risk loci
    • Eriksson N, et al. (2012) Novel associations for hypothyroidism include known autoimmune risk loci. PLoS One. 7:e34442.
    • (2012) Plos One , vol.7
    • Eriksson, N.1
  • 33
    • 84856283235 scopus 로고    scopus 로고
    • Meta-analysis of genomewide association studies identifies three new risk loci for atopic dermatitis
    • Paternoster L, et al. (2011) Meta-analysis of genomewide association studies identifies three new risk loci for atopic dermatitis. Nat. Genet. 44:187-92.
    • (2011) Nat. Genet , vol.44 , pp. 187-192
    • Paternoster, L.1
  • 34
    • 84881026639 scopus 로고    scopus 로고
    • A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci
    • Hinds DA, et al. (2013) A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci. Nat. Genet. 45:907-11.
    • (2013) Nat. Genet , vol.45 , pp. 907-911
    • Hinds, D.A.1
  • 35
    • 0033583182 scopus 로고    scopus 로고
    • RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoter
    • Tillotson LG. (1999) RIN ZF, a novel zinc finger gene, encodes proteins that bind to the CACC element of the gastrin promoter. J. Biol. Chem. 274:8123-8.
    • (1999) J. Biol. Chem , vol.274 , pp. 8123-8128
    • Tillotson, L.G.1
  • 36
    • 77954497664 scopus 로고    scopus 로고
    • MicroRNA-27a indirectly regulates estrogen receptor α expression and hormone responsiveness in MCF-7 breast cancer cells
    • Li X, et al. (2010) MicroRNA-27a indirectly regulates estrogen receptor α expression and hormone responsiveness in MCF-7 breast cancer cells. Endocrinology. 151:2462-73.
    • (2010) Endocrinology , vol.151 , pp. 2462-2473
    • Li, X.1
  • 37
    • 0034234573 scopus 로고    scopus 로고
    • IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3
    • Tone M, Powell MJ, Tone Y, Thompson SA, Waldmann H. (2000) IL-10 gene expression is controlled by the transcription factors Sp1 and Sp3. J. Immunol. 165:286-91.
    • (2000) J. Immunol , vol.165 , pp. 286-291
    • Tone, M.1    Powell, M.J.2    Tone, Y.3    Thompson, S.A.4    Waldmann, H.5
  • 38
    • 0037088690 scopus 로고    scopus 로고
    • The role of Sp1 and NF-kappa B in regulating CD40 gene expression
    • Tone M, Tone Y, Babik JM, Lin CY, Waldmann H. (2002) The role of Sp1 and NF-kappa B in regulating CD40 gene expression. J. Biol. Chem. 277:8890-7.
    • (2002) J. Biol. Chem , vol.277 , pp. 8890-8897
    • Tone, M.1    Tone, Y.2    Babik, J.M.3    Lin, C.Y.4    Waldmann, H.5
  • 39
    • 40449131545 scopus 로고    scopus 로고
    • Estrogen receptor-alpha deficiency attenuates autoimmune disease in (NZB x NZW)F1 mice
    • Bynote KK, et al. (2008) Estrogen receptor-alpha deficiency attenuates autoimmune disease in (NZB x NZW)F1 mice. Genes Immun. 9:137-52.
    • (2008) Genes Immun , vol.9 , pp. 137-152
    • Bynote, K.K.1
  • 41
    • 84905986608 scopus 로고    scopus 로고
    • The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey
    • Kaya GA, et al. (2014) The association of PTPN22 R620W polymorphism is stronger with late-onset AChR-myasthenia gravis in Turkey. PLoS One. 9:e104760.
    • (2014) Plos One , vol.9
    • Kaya, G.A.1
  • 42
    • 12144291502 scopus 로고    scopus 로고
    • A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
    • Bottini N, et al. (2004) A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat. Genet. 36:337-8.
    • (2004) Nat. Genet , vol.36 , pp. 337-338
    • Bottini, N.1
  • 43
    • 3242713277 scopus 로고    scopus 로고
    • A missense singlenucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
    • Begovich AB, et al. (2004) A missense singlenucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am. J. Hum. Genet. 75:330-7.
    • (2004) Am. J. Hum. Genet , vol.75 , pp. 330-337
    • Begovich, A.B.1
  • 44
    • 4143105691 scopus 로고    scopus 로고
    • Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
    • Kyogoku C, et al. (2004) Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am. J. Hum. Genet. 75:504-7.
    • (2004) Am. J. Hum. Genet , vol.75 , pp. 504-507
    • Kyogoku, C.1
  • 45
    • 84897106158 scopus 로고    scopus 로고
    • Tyrosine phosphatase PTPN22: Multifunctional regulator of immune signaling, development, and disease
    • Bottini N, Peterson EJ. (2014) Tyrosine phosphatase PTPN22: multifunctional regulator of immune signaling, development, and disease. Ann. Rev. Immunol. 32:83-119.
    • (2014) Ann. Rev. Immunol , vol.32 , pp. 83-119
    • Bottini, N.1    Peterson, E.J.2
  • 46
    • 0033987358 scopus 로고    scopus 로고
    • Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis
    • Hughes AE, et al. (2000) Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis. Nat. Genet. 24:45-8.
    • (2000) Nat. Genet , vol.24 , pp. 45-48
    • Hughes, A.E.1
  • 47
    • 46349084493 scopus 로고    scopus 로고
    • Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations
    • Guerrini MM, et al. (2008) Human osteoclast-poor osteopetrosis with hypogammaglobulinemia due to TNFRSF11A (RANK) mutations. Am. J. Hum. Genet. 83:64-76.
    • (2008) Am. J. Hum. Genet , vol.83 , pp. 64-76
    • Guerrini, M.M.1
  • 48
    • 77952884683 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget’s disease of bone
    • Albagha OM, et al. (2010) Genome-wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget’s disease of bone. Nat. Genet. 42:520-4.
    • (2010) Nat. Genet , vol.42 , pp. 520-524
    • Albagha, O.M.1
  • 49
    • 84860331458 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
    • Estrada K, et al. (2012) Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat. Genet. 44:491-501.
    • (2012) Nat. Genet , vol.44 , pp. 491-501
    • Estrada, K.1
  • 50
    • 84858795036 scopus 로고    scopus 로고
    • Rank signaling links the development of invariant gammadelta T cell progenitors and Aire(+) medullary epithelium
    • Roberts NA, et al. (2012) Rank signaling links the development of invariant gammadelta T cell progenitors and Aire(+) medullary epithelium. Immunity. 36:427-37.
    • (2012) Immunity , vol.36 , pp. 427-437
    • Roberts, N.A.1
  • 51
    • 0030714605 scopus 로고    scopus 로고
    • A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
    • Anderson DM, et al. (1997) A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature. 390:175-9.
    • (1997) Nature , vol.390 , pp. 175-179
    • Anderson, D.M.1
  • 52
    • 0033568341 scopus 로고    scopus 로고
    • RANK is essential for osteoclast and lymph node development
    • Dougall WC, et al. (1999) RANK is essential for osteoclast and lymph node development. Genes Dev. 13:2412-24.
    • (1999) Genes Dev , vol.13 , pp. 2412-2424
    • Dougall, W.C.1
  • 53
    • 33846987571 scopus 로고    scopus 로고
    • Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases
    • Mewar D, et al. (2006) Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases. Genes Immun. 7:625-31.
    • (2006) Genes Immun , vol.7 , pp. 625-631
    • Mewar, D.1
  • 54
    • 78049246370 scopus 로고    scopus 로고
    • HLA class I and genetic susceptibility to type 1 diabetes: Results from the type 1 Diabetes Genetics Consortium
    • Noble JA, et al. (2010) HLA class I and genetic susceptibility to type 1 diabetes: results from the type 1 Diabetes Genetics Consortium. Diabetes. 59:2972-9.
    • (2010) Diabetes , vol.59 , pp. 2972-2979
    • Noble, J.A.1
  • 55
    • 84862776511 scopus 로고    scopus 로고
    • Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis
    • Raychaudhuri S, et al. (2012) Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis. Nat. Genet. 44:291-6.
    • (2012) Nat. Genet , vol.44 , pp. 291-296
    • Raychaudhuri, S.1
  • 56
    • 18544362452 scopus 로고    scopus 로고
    • Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis
    • Jawaheer D, et al. (2002) Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. Am. J. Hum. Genet. 71:585-94.
    • (2002) Am. J. Hum. Genet , vol.71 , pp. 585-594
    • Jawaheer, D.1
  • 57
    • 84868444383 scopus 로고    scopus 로고
    • Unraveling multiple MHC gene associations with systemic lupus erythematosus: Model choice indicates a role for HLA alleles and non-HLA genes in Europeans
    • Morris DL, et al. (2012) Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in Europeans. Am. J. Hum. Genet. 91:778-93.
    • (2012) Am. J. Hum. Genet , vol.91 , pp. 778-793
    • Morris, D.L.1
  • 58
    • 44349191058 scopus 로고    scopus 로고
    • BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility
    • Quinones-Lombrana A, et al. (2008) BAT1 promoter polymorphism is associated with rheumatoid arthritis susceptibility. J. Rheumatol. 35:741-4.
    • (2008) J. Rheumatol , vol.35 , pp. 741-744
    • Quinones-Lombrana, A.1
  • 59
    • 84906101114 scopus 로고    scopus 로고
    • Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia
    • Gockel I, et al. (2014) Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nat. Genet. 46:901-4.
    • (2014) Nat. Genet , vol.46 , pp. 901-904
    • Gockel, I.1
  • 60
    • 0344802410 scopus 로고
    • Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes
    • McMichael AJ, Gotch FM, Santos-Aguado J, Strominger JL. (1988) Effect of mutations and variations of HLA-A2 on recognition of a virus peptide epitope by cytotoxic T lymphocytes. Proc. Natl. Acad. Sci. U. S. A. 85:9194-8.
    • (1988) Proc. Natl. Acad. Sci. U. S. A , vol.85 , pp. 9194-9198
    • McMichael, A.J.1    Gotch, F.M.2    Santos-Aguado, J.3    Strominger, J.L.4
  • 61
    • 34147103812 scopus 로고    scopus 로고
    • Clonal expansions of CD4+ B helper T cells in autoimmune myasthenia gravis
    • Tackenberg B, et al. (2007) Clonal expansions of CD4+ B helper T cells in autoimmune myasthenia gravis. Eur. J. Immunol. 37:849-63.
    • (2007) Eur. J. Immunol , vol.37 , pp. 849-863
    • Tackenberg, B.1
  • 63
    • 0034237540 scopus 로고    scopus 로고
    • SFEMG in ocular myasthenia gravis diagnosis
    • Padua L, et al. (2000) SFEMG in ocular myasthenia gravis diagnosis. Clin. Neurophysiol. 111:1203-7.
    • (2000) Clin. Neurophysiol , vol.111 , pp. 1203-1207
    • Padua, L.1
  • 64
    • 65649121159 scopus 로고    scopus 로고
    • Correlating extent of neuromuscular instability with acetylcholine receptor antibodies
    • Farrugia ME, Jacob S, Sarrigiannis PG, Kennett RP. (2009) Correlating extent of neuromuscular instability with acetylcholine receptor antibodies. Muscle Nerve. 39:489-93.
    • (2009) Muscle Nerve , vol.39 , pp. 489-493
    • Farrugia, M.E.1    Jacob, S.2    Sarrigiannis, P.G.3    Kennett, R.P.4
  • 65
    • 79960889595 scopus 로고    scopus 로고
    • Electrophysiological and immunological study in myasthenia gravis: Diagnostic sensitivity and correlation
    • Witoonpanich R, Dejthevaporn C, Sriphrapradang A, Pulkes T. (2011) Electrophysiological and immunological study in myasthenia gravis: diagnostic sensitivity and correlation. Clin. Neurophysiol. 122:1873-7.
    • (2011) Clin. Neurophysiol , vol.122 , pp. 1873-1877
    • Witoonpanich, R.1    Dejthevaporn, C.2    Sriphrapradang, A.3    Pulkes, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.