Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DBQ1, -DRB1 disease loci

Human Molecular Genetics

Volumn 10, Issue 8, 2001, Pages 881-889

  Zavattari, Patrizia ^a   Lampis, Rosanna ^a   Motzo, Costantino ^a   Loddo, Miriam ^a,b   Mulargia, Annapaola ^a,b   Whalen, Michael ^a   Maioli, Mario ^c   Angius, Efisio ^b   Todd, John A ^d   Cucca, Francesco ^a  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b BROTZU HOSPITAL   (Italy)

^c UNIVERSITY OF SASSARI   (Italy)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN;

ADOLESCENT; ADULT; ALLELE; ARTICLE; CHILD; CHROMOSOME 6P; CONTROLLED STUDY; DISEASE ASSOCIATION; EXON; FEMALE; FOUNDER EFFECT; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; HAPLOTYPE; HLA SYSTEM; HUMAN; INDEPENDENCE; INFANT; INHERITANCE; INSULIN DEPENDENT DIABETES MELLITUS; ITALY; MAJOR CLINICAL STUDY; MALE; MARKER GENE; POPULATION; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM;

CHROMOSOME MAPPING; DIABETES MELLITUS, TYPE 1; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; LINKAGE DISEQUILIBRIUM; RISK FACTORS;

EID: 0035311823     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

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13. On measures of gametic disequilibrium
14. Gametic disequilibrium measures: Proceed with caution
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