Epidemiology of acute kidney injury in children worldwide, including developing countries

Pediatric Nephrology

Volumn 32, Issue 8, 2017, Pages 1301-1314

  Lameire, Norbert ^a   Van Biesen, Wim ^a   Vanholder, Raymond ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Definitions of AKI; Low income countries; Pediatric AKI; Worldwide epidemiology

Indexed keywords

BIOLOGICAL MARKER; CYSTATIN C; CREATININE;

ACUTE KIDNEY FAILURE; ADULT; AFRICA SOUTH OF THE SAHARA; CHILD; CRITICALLY ILL PATIENT; DEVELOPING COUNTRY; DISEASE CLASSIFICATION; GLOBAL DISEASE BURDEN; HOSPITALIZED CHILD; HUMAN; INTERNATIONAL COOPERATION; KIDNEY DISEASE; LOW INCOME COUNTRY; MEDICAL TERMINOLOGY; META ANALYSIS (TOPIC); PEDIATRICS; PRIORITY JOURNAL; RENAL ANGINA; REVIEW; SYSTEMATIC REVIEW (TOPIC); BLOOD; CRITICAL ILLNESS; KIDNEY; PATHOLOGY; PEDIATRIC INTENSIVE CARE UNIT; POVERTY; SOCIAL DETERMINANTS OF HEALTH; STATISTICS AND NUMERICAL DATA;

ACUTE KIDNEY INJURY; AFRICA SOUTH OF THE SAHARA; BIOMARKERS; CHILD; CREATININE; CRITICAL ILLNESS; DEVELOPING COUNTRIES; HUMANS; INTENSIVE CARE UNITS, PEDIATRIC; KIDNEY; POVERTY; SOCIAL DETERMINANTS OF HEALTH;

EID: 84974851986     PISSN: 0931041X     EISSN: 1432198X     Source Type: Journal    
DOI: 10.1007/s00467-016-3433-2     Document Type: Review

References (113)

1. Liano F, Pascual J (1996) Epidemiology of acute renal failure: a prospective, multicenter, community-based study. Madrid Acute Renal Failure Study Group. Kidney Int 50:811–818
2. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, Schetz M, Tan I, Bouman C, Macedo E, Gibney N, Tolwani A, Ronco C (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294:813–818
3. Bellomo R, Kellum JA, Ronco C (2012) Acute kidney injury. Lancet 380:756–766
4. Chertow GM, Burdick E, Honour M, Bonventre JV, Bates DW (2005) Acute kidney injury, mortality, length of stay, and costs in hospitalized patients. J Am Soc Nephrol 16:3365–3370
5. Lassnigg A, Schmidlin D, Mouhieddine M, Bachmann LM, Druml W, Bauer P, Hiesmayr M (2004) Minimal changes of serum creatinine predict prognosis in patients after cardiothoracic surgery: a prospective cohort study. J Am Soc Nephrol 15:1597–1605
6. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P (2004) Acute renal failure—definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 8:R204–R212
7. Akcan-Arikan A, Zappitelli M, Loftis LL, Washburn KK, Jefferson LS, Goldstein SL (2007) Modified RIFLE criteria in critically ill children with acute kidney injury. Kidney Int 71:1028–1035
8. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A (2007) Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 11:R31
9. Kidney Diseases Improving Global Outcomes (2012) KDIGO clinical practice guideline for acute kidney injury. Kidney Int 2[Suppl 1]:1–138
10. Kellum JA, Sileanu FE, Murugan R, Lucko N, Shaw AD, Clermont G (2015) Classifying AKI by urine output versus serum creatinine level. J Am Soc Nephrol 26:2231–2238
11. Macedo E, Malhotra R, Bouchard J, Wynn SK, Mehta RL (2011) Oliguria is an early predictor of higher mortality in critically ill patients. Kidney Int 80:760–767
12. Vanmassenhove J, Glorieux G, Hoste E, Dhondt A, Vanholder R, Van Biesen W (2013) Urinary output and fractional excretion of sodium and urea as indicators of transient versus intrinsic acute kidney injury during early sepsis. Crit Care 17:R234
13. Wlodzimirow KA, Bu-Hanna A, Slabbekoorn M, Chamuleau RA, Schultz MJ, Bouman CS (2012) A comparison of RIFLE with and without urine output criteria for acute kidney injury in critically ill patients. Crit Care 16:R200
14. Kellum JA (2015) Diagnostic criteria for acute kidney injury: present and future. Crit Care Clin 31:621–632
15. Rewa O, Bagshaw SM (2014) Acute kidney injury—epidemiology, outcomes and economics. Nat Rev Nephrol 10:193–207
16. Schwartz GJ, Haycock GB, Edelmann CM Jr, Spitzer A (1976) A simple estimate of glomerular filtration rate in children derived from body length and plasma creatinine. Pediatrics 58:259–263
17. Schwartz GJ, Work DF (2009) Measurement and estimation of GFR in children and adolescents. Clin J Am Soc Nephrol 4:1832–1843
18. Kavaz A, Ozcakar ZB, Kendirli T, Ozturk BB, Ekim M, Yalcinkaya F (2012) Acute kidney injury in a paediatric intensive care unit: comparison of the pRIFLE and AKIN criteria. Acta Paediatr 101:e126–e129
19. Lex DJ, Toth R, Cserep Z, Alexander SI, Breuer T, Sapi E, Szatmari A, Szekely E, Gal J, Szekely A (2014) A comparison of the systems for the identification of postoperative acute kidney injury in pediatric cardiac patients. Ann Thorac Surg 97:202–210
20. Zappitelli M, Parikh CR, Kcan-Arikan A, Washburn KK, Moffett BS, Goldstein SL (2008) Ascertainment and epidemiology of acute kidney injury varies with definition interpretation. Clin J Am Soc Nephrol 3:948–954
21. Alkandari O, Eddington KA, Hyder A, Gauvin F, Ducruet T, Gottesman R, Phan V, Zappitelli M (2011) Acute kidney injury is an independent risk factor for pediatric intensive care unit mortality, longer length of stay and prolonged mechanical ventilation in critically ill children: a two-center retrospective cohort study. Crit Care 15:R146
22. Plotz FB, Bouma AB, van Wijk JA, Kneyber MC, Bokenkamp A (2008) Pediatric acute kidney injury in the ICU: an independent evaluation of pRIFLE criteria. Intensive Care Med 34:1713–1717
23. Sanchez-Pinto LN, Goldstein SL, Schneider JB, Khemani RG (2015) Association between progression and improvement of acute kidney injury and mortality in critically ill children. Pediatr Crit Care Med 16:703–710
24. Askenazi DJ, Griffin R, McGwin G, Carlo W, Ambalavanan N (2009) Acute kidney injury is independently associated with mortality in very low birthweight infants: a matched case–control analysis. Pediatr Nephrol 24:991–997
25. Gadepalli SK, Selewski DT, Drongowski RA, Mychaliska GB (2011) Acute kidney injury in congenital diaphragmatic hernia requiring extracorporeal life support: an insidious problem. J Pediatr Surg 46:630–635
26. Karlowicz MG, Adelman RD (1995) Nonoliguric and oliguric acute renal failure in asphyxiated term neonates. Pediatr Nephrol 9:718–722
27. Kellum JA, Levin N, Bouman C, Lameire N (2002) Developing a classification system for acute renal failure. Curr Opin Crit Care 8:509–514
28. Cataldi L, Mussap M, Bertelli L, Ruzzante N, Fanos V, Plebani M (1999) Cystatin C in healthy women at term pregnancy and in their infant newborns: relationship between maternal and neonatal serum levels and reference values. Am J Perinatol 16:287–295
29. Fanos V, Mussap M, Plebani M, Cataldi L (1999) Cystatin C in paediatric nephrology. Present situation and prospects. Minerva Pediatr 51:167–177
30. Grubb AO (2000) Cystatin C—properties and use as diagnostic marker. Adv Clin Chem 35:63–99
31. Laterza OF, Price CP, Scott MG (2002) Cystatin C: an improved estimator of glomerular filtration rate? Clin Chem 48:699–707
32. Briguori C, Visconti G, Rivera NV, Focaccio A, Golia B, Giannone R, Castaldo D, De MF, Ricciardelli B, Colombo A (2010) Cystatin C and contrast-induced acute kidney injury. Circulation 121:2117–2122
33. Ebru AE, Kilic A, Korkmaz FS, Seker R, Sasmaz H, Demirtas S, Biyikli Z (2014) Is cystatin-C superior to creatinine in the early diagnosis of contrast-induced nephropathy?: a potential new biomarker for an old complication. J Postgrad Med 60:135–140
34. Quintavalle C, Fiore D, De MF, Visconti G, Focaccio A, Golia B, Ricciardelli B, Donnarumma E, Bianco A, Zabatta MA, Troncone G, Colombo A, Briguori C, Condorelli G (2012) Impact of a high loading dose of atorvastatin on contrast-induced acute kidney injury. Circulation 126:3008–3016
35. Ricci Z, Luciano R, Favia I, Garisto C, Muraca M, Morelli S, Di CL, Cogo P, Picardo S (2011) High-dose fenoldopam reduces postoperative neutrophil gelatinase-associated lipocaline and cystatin C levels in pediatric cardiac surgery. Crit Care 15:R160
36. Tanaga K, Tarao K, Nakamura Y, Inoue T, Jo K, Ishikawa T, Miyazaki A (2012) Percutaneous coronary intervention causes increase of serum cystatin C concentration even in the patients with a low risk of contrast-induced nephropathy. Cardiovasc Interv Ther 27:168–173
37. Zappitelli M, Krawczeski CD, Devarajan P, Wang Z, Sint K, Thiessen-Philbrook H, Li S, Bennett MR, Ma Q, Shlipak MG, Garg AX, Parikh CR (2011) Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery. Kidney Int 80:655–662
38. Zappitelli M, Greenberg JH, Coca SG, Krawczeski CD, Li S, Thiessen-Philbrook HR, Bennett MR, Devarajan P, Parikh CR (2015) Association of definition of acute kidney injury by cystatin C rise with biomarkers and clinical outcomes in children undergoing cardiac surgery. JAMA Pediatr 169:583–591
39. Schwartz GJ, Munoz A, Schneider MF, Mak RH, Kaskel F, Warady BA, Furth SL (2009) New equations to estimate GFR in children with CKD. J Am Soc Nephrol 20:629–637
40. Zappitelli M, Parvex P, Joseph L, Paradis G, Grey V, Lau S, Bell L (2006) Derivation and validation of cystatin C-based prediction equations for GFR in children. Am J Kidney Dis 48:221–230
41. Lagos-Arevalo P, Palijan A, Vertullo L, Devarajan P, Bennett MR, Sabbisetti V, Bonventre JV, Ma Q, Gottesman RD, Zappitelli M (2015) Cystatin C in acute kidney injury diagnosis: early biomarker or alternative to serum creatinine? Pediatr Nephrol 30:665–676
42. Alge JL, Arthur JM (2015) Biomarkers of AKI: a review of mechanistic relevance and potential therapeutic implications. Clin J Am Soc Nephrol 10:147–155
43. Chen LX, Koyner JL (2015) Biomarkers in Acute Kidney Injury. Crit Care Clin 31:633–648
44. de Geus HRH, Betjes MG, Bakker J (2012) Biomarkers for the prediction of acute kidney injury: a narrative review on current status and future challenges. Clin Kidney J 5:102–108
45. Endre ZH, Kellum JA, Di SS, Doi K, Goldstein SL, Koyner JL, Macedo E, Mehta RL, Murray PT (2013) Differential diagnosis of AKI in clinical practice by functional and damage biomarkers: workgroup statements from the tenth Acute Dialysis Quality Initiative Consensus Conference. Contrib Nephrol 182:30–44
46. Endre ZH, Pickering JW (2014) Acute kidney injury: cell cycle arrest biomarkers win race for AKI diagnosis. Nat Rev Nephrol 10:683–685
47. Wasung ME, Chawla LS, Madero M (2015) Biomarkers of renal function, which and when? Clin Chim Acta 438:350–357
48. Vanmassenhove J, Vanholder R, Nagler E, Van Biesen W (2012) Urinary and serum biomarkers for the diagnosis of acute kidney injury:an in depth review of the literature. Nephrol Dial Transplant 28:254–273
49. Ostermann M, Joannidis M (2015) Biomarkers for AKI improve clinical practice: no. Intensive Care Med 41:618–622
50. Meersch M, Schmidt C, Van AH, Rossaint J, Gorlich D, Stege D, Malec E, Januszewska K, Zarbock A (2014) Validation of cell-cycle arrest biomarkers for acute kidney injury after pediatric cardiac surgery. PLoS One 9:e110865
51. Mishra J, Dent C, Tarabishi R, Mitsnefes MM, Ma Q, Kelly C, Ruff SM, Zahedi K, Shao M, Bean J, Mori K, Barasch J, Devarajan P (2005) Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery. Lancet 365:1231–1238
52. Westhoff JH, Tonshoff B, Waldherr S, Poschl J, Teufel U, Westhoff TH, Fichtner A (2015) Urinary tissue inhibitor of metalloproteinase-2 (TIMP-2) • insulin-like growth factor-binding protein 7 (IGFBP7) predicts adverse outcome in pediatric acute kidney injury. PLoS One 10:e0143628
53. Bell M, Larsson A, Venge P, Bellomo R, Martensson J (2015) Assessment of cell-cycle arrest biomarkers to predict early and delayed acute kidney injury. Dis Markers 2015:158658
54. Goldstein SL, Chawla LS (2010) Renal angina. Clin J Am Soc Nephrol 5:943–949
55. Chawla LS (2015) Introduction: sepsis-associated AKI. Semin Nephrol 35:1
56. Basu RK, Zappitelli M, Brunner L, Wang Y, Wong HR, Chawla LS, Wheeler DS, Goldstein SL (2014) Derivation and validation of the renal angina index to improve the prediction of acute kidney injury in critically ill children. Kidney Int 85:659–667
57. Siew ED, Furth SL (2014) Acute kidney injury: a not-so-silent disease. Kidney Int 85:494–495
58. Basu RK, Wang Y, Wong HR, Chawla LS, Wheeler DS, Goldstein SL (2014) Incorporation of biomarkers with the renal angina index for prediction of severe AKI in critically ill children. Clin J Am Soc Nephrol 9:654–662
59. Siew ED, Davenport A (2015) The growth of acute kidney injury: a rising tide or just closer attention to detail? Kidney Int 87:46–61
60. Zappitelli M (2008) Epidemiology and diagnosis of acute kidney injury. Semin Nephrol 28:436–446
61. Jetton JG, Askenazi DJ (2012) Update on acute kidney injury in the neonate. Curr Opin Pediatr 24:191–196
62. Selewski DT, Symons JM (2014) Acute kidney injury. Pediatr Rev 35:30–41
63. Selewski DT, Charlton JR, Jetton JG, Guillet R, Mhanna MJ, Askenazi DJ, Kent AL (2015) Neonatal acute kidney injury. Pediatrics 136:e463–e473
64. Hsu CW, Symons JM (2010) Acute kidney injury: can we improve prognosis? Pediatr Nephrol 25:2401–2412
65. Bailey D, Phan V, Litalien C, Ducruet T, Merouani A, Lacroix J, Gauvin F (2007) Risk factors of acute renal failure in critically ill children: A prospective descriptive epidemiological study. Pediatr Crit Care Med 8:29–35
66. Sutherland SM, Byrnes JJ, Kothari M, Longhurst CA, Dutta S, Garcia P, Goldstein SL (2015) AKI in hospitalized children: comparing the pRIFLE, AKIN, and KDIGO definitions. Clin J Am Soc Nephrol 10:554–561
67. Duzova A, Bakkaloglu A, Kalyoncu M, Poyrazoglu H, Delibas A, Ozkaya O, Peru H, Alpay H, Soylemezoglu O, Gur-Guven A, Bak M, Bircan Z, Cengiz N, Akil I, Ozcakar B, Uncu N, Karabay-Bayazit A, Sonmez F (2010) Etiology and outcome of acute kidney injury in children. Pediatr Nephrol 25:1453–1461
68. Pundziene B, Dobiliene D, Rudaitis S (2010) Acute kidney injury in pediatric patients: experience of a single center during an 11-year period. Medicina (Kaunas) 46:511–515
69. Zappitelli M, Moffett BS, Hyder A, Goldstein SL (2010) Acute kidney injury in non-critically ill children treated with aminoglycoside antibiotics in a tertiary healthcare centre: a retrospective cohort study. Nephrol Dial Transplant 26:144–150
70. Goldstein SL, Kirkendall E, Nguyen H, Schaffzin JK, Bucuvalas J, Bracke T, Seid M, Ashby M, Foertmeyer N, Brunner L, Lesko A, Barclay C, Lannon C, Muething S (2013) Electronic health record identification of nephrotoxin exposure and associated acute kidney injury. Pediatrics 132:e756–e767
71. Rheault MN, Zhang L, Selewski DT, Kallash M, Tran CL, Seamon M, Katsoufis C, Ashoor I, Hernandez J, Supe-Markovina K, Essandri-Silva C, Jesus-Gonzalez N, Vasylyeva TL, Formeck C, Woll C, Gbadegesin R, Geier P, Devarajan P, Carpenter SL, Kerlin BA, Smoyer WE (2015) AKI in children hospitalized with nephrotic syndrome. Clin J Am Soc Nephrol 10:2110–2118
72. Misurac JM, Knoderer CA, Leiser JD, Nailescu C, Wilson AC, Andreoli SP (2013) Nonsteroidal anti-inflammatory drugs are an important cause of acute kidney injury in children. J Pediatr 162:1153–1159
73. Sutherland SM, Ji J, Sheikhi FH, Widen E, Tian L, Alexander SR, Ling XB (2013) AKI in hospitalized children: epidemiology and clinical associations in a national cohort. Clin J Am Soc Nephrol 8:1661–1669
74. McGregor TL, Jones DP, Wang L, Danciu I, Bridges BC, Fleming GM, Shirey-Rice J, Chen L, Byrne DW, Van Driest SL (2016) Acute kidney injury incidence in noncritically ill hospitalized children, adolescents, and young adults: a retrospective observational study. Am J Kidney Dis 67:384–390
75. Jenssen GR, Hovland E, Bangstad HJ, Nygard K, Vold L, Bjerre A (2014) The incidence and aetiology of acute kidney injury in children in Norway between 1999 and 2008. Acta Paediatr 103:1192–1197
76. Vachvanichsanong P, Dissaneewate P, Lim A, McNeil E (2006) Childhood acute renal failure: 22-year experience in a university hospital in southern Thailand. Pediatrics 118:e786–e791
77. Schneider J, Khemani R, Grushkin C, Bart R (2010) Serum creatinine as stratified in the RIFLE score for acute kidney injury is associated with mortality and length of stay for children in the pediatric intensive care unit. Crit Care Med 38:933–939
78. Chang JW, Jeng MJ, Yang LY, Chen TJ, Chiang SC, Soong WJ, Wu KG, Lee YS, Wang HH, Yang CF, Tsai HL (2015) The epidemiology and prognostic factors of mortality in critically ill children with acute kidney injury in Taiwan. Kidney Int 87:632–639
79. Selewski DT, Cornell TT, Heung M, Troost JP, Ehrmann BJ, Lombel RM, Blatt NB, Luckritz K, Hieber S, Gajarski R, Kershaw DB, Shanley TP, Gipson DS (2014) Validation of the KDIGO acute kidney injury criteria in a pediatric critical care population. Intensive Care Med 40:1481–1488
80. Basu RK, Kaddourah A, Terrell T, Mottes T, Arnold P, Jacobs J, Andringa J, Goldstein SL (2015) Assessment of Worldwide Acute Kidney Injury, Renal Angina and Epidemiology in critically ill children (AWARE): study protocol for a prospective observational study. BMC Nephrol 16:24
81. Lindle KA, Dinh K, Moffett BS, Kyle WB, Montgomery NM, Denfield SD, Knudson JD (2014) Angiotensin-converting enzyme inhibitor nephrotoxicity in neonates with cardiac disease. Pediatr Cardiol 35:499–506
82. McKamy S, Hernandez E, Jahng M, Moriwaki T, Deveikis A, Le J (2011) Incidence and risk factors influencing the development of vancomycin nephrotoxicity in children. J Pediatr 158:422–426
83. Moffett BS, Goldstein SL (2011) Acute kidney injury and increasing nephrotoxic-medication exposure in noncritically-ill children. Clin J Am Soc Nephrol 6:856–863
84. Moffett BS, Hilvers PS, Dinh K, Arikan AA, Checchia P, Bronicki R (2015) Vancomycin-associated acute kidney injury in pediatric cardiac intensive care patients. Congenit Heart Dis 10:E6–E10
85. Moffett BS, Goldstein SL, Adusei M, Kuzin J, Mohan P, Mott AR (2011) Risk factors for postoperative acute kidney injury in pediatric cardiac surgery patients receiving angiotensin-converting enzyme inhibitors. Pediatr Crit Care Med 12:555–559
86. Joo EJ, Peck KR, Ha YE, Kim YS, Song YG, Lee SS, Ryu SY, Moon C, Lee CS, Park KH (2013) Impact of acute kidney injury on mortality and medical costs in patients with meticillin-resistant Staphylococcus aureus bacteraemia: a retrospective, multicentre observational study. J Hosp Infect 83:300–306
87. Basu RK, Andrews A, Krawczeski C, Manning P, Wheeler DS, Goldstein SL (2013) Acute kidney injury based on corrected serum creatinine is associated with increased morbidity in children following the arterial switch operation. Pediatr Crit Care Med 14:e218–e224
88. Cao Y, Yi ZW, Zhang H, Dang XQ, Wu XC, Huang AW (2013) Etiology and outcomes of acute kidney injury in Chinese children: a prospective multicentre investigation. BMC Urol 13:41
89. Mammen C, Al AA, Skippen P, Nadel H, Levine D, Collet JP, Matsell DG (2012) Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit: a prospective cohort study. Am J Kidney Dis 59:523–530
90. Fortenberry JD, Paden ML, Goldstein SL (2013) Acute kidney injury in children: an update on diagnosis and treatment. Pediatr Clin N Am 60:669–688
91. Askenazi DJ, Feig DI, Graham NM, Hui-Stickle S, Goldstein SL (2006) 3–5 year longitudinal follow-up of pediatric patients after acute renal failure. Kidney Int 69:184–189
92. Cerda J (2008) World Kidney Day and acute kidney injury. Kidney Int 73:1441
93. Lameire NH, Bagga A, Cruz D, De Maeseneer J, Endre Z, Kellum JA, Liu KD, Mehta RL, Pannu N, Van Biesen W, Vanholder R (2013) Acute kidney injury: an increasing global concern. Lancet 382:170–179
94. Lewington AJ, Cerda J, Mehta RL (2013) Raising awareness of acute kidney injury: a global perspective of a silent killer. Kidney Int 84:457–467
95. Mehta RL, Cerda J, Burdmann EA, Tonelli M, Garcia-Garcia G, Jha V, Susantitaphong P, Rocco M, Vanholder R, Sever MS, Cruz D, Jaber B, Lameire NH, Lombardi R, Lewington A, Feehally J, Finkelstein F, Levin N, Pannu N, Thomas B, Ronoff-Spencer E, Remuzzi G (2015) International Society of Nephrology’s 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology. Lancet 385:2616–2643
96. Cerda J, Bagga A, Kher V, Chakravarthi RM (2008) The contrasting characteristics of acute kidney injury in developed and developing countries. Nat Clin Pract Nephrol 4:138–153
97. Cerda J, Lameire N, Eggers P, Pannu N, Uchino S, Wang H, Bagga A, Levin A (2008) Epidemiology of acute kidney injury. Clin J Am Soc Nephrol 3:881–886
98. Remuzzi G, Horton R (2013) Acute renal failure: an unacceptable death sentence globally. Lancet 382:2041–2042
99. Finkelstein FO, Smoyer WE, Carter M, Brusselmans A, Feehally J (2014) Peritoneal dialysis, acute kidney injury, and the Saving Young Lives program. Perit Dial Int 34:478–480
100. Susantitaphong P, Cruz DN, Cerda J, Abulfaraj M, Alqahtani F, Koulouridis I, Jaber BL, for the Acute Kidney Advisory Group of the American society of Nephrology (2013) World incidence of AKI: a meta-analysis. Clin J Am Soc Nephrol 8:1482–1493
101. Jha V, Parameswaran S (2013) Community-acquired acute kidney injury in tropical countries. Nat Rev Nephrol 9:278–290
102. Lameire N, Van Biesen W, Vanholder R (2006) The changing epidemiology of acute renal failure. Nat Clin Pract Nephrol 2:364–377
103. Lombardi R, Yu L, Younes-Ibrahim M, Schor N, Burdmann EA (2008) Epidemiology of acute kidney injury in Latin America. Semin Nephrol 28:320–329
104. Naicker S, Aboud O, Gharbi MB (2008) Epidemiology of acute kidney injury in Africa. Semin Nephrol 28:348–353
105. Olowu WA, Niang A, Osafo C, Ashuntantang G, Arogundade FA, Porter J, Naicker S, Luyckx VA (2016) Outcomes of acute kidney injury in children and adults in sub-Saharan Africa: a systematic review. Lancet Glob Health 4:e242–e250
106. Aloni MN, Nsibu CN, Meeko-Mimaniye M, Ekulu PM, Bodi JM (2012) Acute renal failure in Congolese children: a tertiary institution experience. Acta Paediatr 101:e514–e518
107. Balaka B, Agbere D, Bonkoungou P, Gnamey D, Kessie K, Assimadi K (2003) Post-hemolytic renal failure in children with glucose-6-phosphate dehydrogenase deficiency at the University Hospital Center in Lome. Med Trop (Mars) 63:151–154
108. Bodi JM, Nsibu CN, Aloni MN, Lukute GN, Kunuanuna TS, Tshibassu PM, Pakasa N (2014) Black water fever associated with acute renal failure among Congolese children in Kinshasa. Saudi J Kidney Dis Transpl 25:1352–1358
109. Burchard GD, Ehrhardt S, Mockenhaupt FP, Mathieu A, Gana-Nsiire P, Anemana SD, Otchwemah RN, Abel W, Brattig N (2003) Renal dysfunction in children with uncomplicated, Plasmodium falciparum malaria in Tamale, Ghana. Ann Trop Med Parasitol 97:345–350
110. Olowu WA, Adefehinti O, Bisiriyu AL (2012) Hospital-acquired acute kidney injury in critically ill children and adolescents. Saudi J Kidney Dis Transpl 23:68–77
111. Esezobor CI, Ladapo TA, Osinaike B, Lesi FE (2012) Paediatric acute kidney injury in a tertiary hospital in Nigeria: prevalence, causes and mortality rate. PLoS One 7:e51229
112. Abdelraheem M, Ali ET, Osman R, Ellidir R, Bushara A, Hussein R, Elgailany S, Bakhit Y, Karrar M, Watson A, Abu-Aisha H (2014) Outcome of acute kidney injury in Sudanese children—an experience from a sub-Saharan African unit. Perit Dial Int 34:526–533
113. Perico N, Remuzzi G (2016) Acute kidney injury in low-income and middle-income countries: no longer a death sentence. Lancet Glob Health 4:e216–e217