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7
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Acute kidney injury network: Report of an initiative to improve outcomes in acute kidney injury
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Mehta RL, Kellum JA, Shah SV, et al. Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007; 11:R31.
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Crit Care
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Mehta, R.L.1
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Walker MW, Clark RH, Spitzer AR. Elevation in plasma creatinine and renal failure in premature neonates without major anomalies: terminology, occurrence and factors associated with increased risk. J Perinatol 2011; 31:199-205.
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J Perinatol
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Walker, M.W.1
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12
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78751646746
-
Acute kidney injury and renal replacement therapy independently predict mortality in neonatal and pediatric noncardiac patients on extracorporeal membrane oxygenation
-
Large, retrospective cohort study of AKI in critically ill patients on ECMO, with neonatal data analyzed separately from pediatric data. Large sample size allowed authors to control for confounding variables and demonstrate that AKI and renal replacement therapy are independent risk factors for mortality
-
Askenazi DJ, Ambalavanan N, Hamilton K, et al. Acute kidney injury and renal replacement therapy independently predict mortality in neonatal and pediatric noncardiac patients on extracorporeal membrane oxygenation. Pediatr Crit Care Med 2011; 12:e1-e6. Large, retrospective cohort study of AKI in critically ill patients on ECMO, with neonatal data analyzed separately from pediatric data. Large sample size allowed authors to control for confounding variables and demonstrate that AKI and renal replacement therapy are independent risk factors for mortality.
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Pediatr Crit Care Med
, vol.12
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Askenazi, D.J.1
Ambalavanan, N.2
Hamilton, K.3
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13
-
-
79952398181
-
Acute kidney injury reduces survival in very low birth weight infants
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Largest prospective epidemiologic study of AKI in neonates. Utilized AKIN definition and classified AKI based on severity. Demonstrated association between AKI and outcomes even after controlling for other confounders
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Koralkar R, Ambalavanan N, Levitan EB, et al. Acute kidney injury reduces survival in very low birth weight infants. Pediatr Res 2011; 69:354-358. Largest prospective epidemiologic study of AKI in neonates. Utilized AKIN definition and classified AKI based on severity. Demonstrated association between AKI and outcomes even after controlling for other confounders.
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Pediatr Res
, vol.69
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Koralkar, R.1
Ambalavanan, N.2
Levitan, E.B.3
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14
-
-
84859099530
-
Congenital heart surgery in infants: Effects of acute kidney injury on outcomes
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[Epub ahead of print] First study to utilize the AKIN classification to stage infant AKI outcomes following cardiopulmonary bypass. Supports previous data that shows increased risk of morbidity and mortality with even small changes in SCr as well as progressively worse outcomes with greater AKI severity
-
Blinder JJ, Goldstein SL, Lee VV, et al. Congenital heart surgery in infants: effects of acute kidney injury on outcomes. J Thorac Cardiovasc Surg 2011. [Epub ahead of print] First study to utilize the AKIN classification to stage infant AKI outcomes following cardiopulmonary bypass. Supports previous data that shows increased risk of morbidity and mortality with even small changes in SCr as well as progressively worse outcomes with greater AKI severity.
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(2011)
J Thorac Cardiovasc Surg
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-
Blinder, J.J.1
Goldstein, S.L.2
Lee, V.V.3
-
15
-
-
79954464444
-
Acute kidney injury incongenital diaphragmatic hernia requiring extracorporeal life support: An insidious problem
-
Retrospective chart review that demonstrates an increased risk of mortality with more severe AKI (RIFLE 'failure'). First study to use categorical definition AKI in patients with congenital diaphragmatic hernia on ECMO
-
Gadepalli SK, Selewski DT, Drongowski RA, Mychaliska GB. Acute kidney injury incongenital diaphragmatic hernia requiring extracorporeal life support: an insidious problem. J Pediatr Surg 2011; 46:630-635. Retrospective chart review that demonstrates an increased risk of mortality with more severe AKI (RIFLE 'failure'). First study to use categorical definition AKI in patients with congenital diaphragmatic hernia on ECMO.
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J Pediatr Surg
, vol.46
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Gadepalli, S.K.1
Selewski, D.T.2
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Mychaliska, G.B.4
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16
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Survival of children requiring repeat extracorporeal membrane oxygenation after congenital heart surgery
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Shuhaiber J, Thiagarajan RR, Laussen PC, et al. Survival of children requiring repeat extracorporeal membrane oxygenation after congenital heart surgery. Ann Thorac Surg 2011; 91:1949-1955.
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Shuhaiber, J.1
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17
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Neutrophil gelatinase-associated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypass
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The study demonstrates the ability of urinary NGAL to predict AKI within hours after injury (CPB) in neonates and provides important information regarding optimal cutoff values for both plasma and urine NGAL. It illustrates that thresholds for neonatal urinary biomarkers are likely different from those in older children due to immature renal tubules
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Krawczeski CD, Woo JG, Wang Y, et al. Neutrophil gelatinase-associated lipocalin concentrations predict development of acute kidney injury in neonates and children after cardiopulmonary bypass. J Pediatr 2011; 158:1009-1015; e1. The study demonstrates the ability of urinary NGAL to predict AKI within hours after injury (CPB) in neonates and provides important information regarding optimal cutoff values for both plasma and urine NGAL. It illustrates that thresholds for neonatal urinary biomarkers are likely different from those in older children due to immature renal tubules.
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(2011)
J Pediatr
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Krawczeski, C.D.1
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18
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Evaluation of glomerular and tubular renal function in neonates with birth asphyxia
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Kaur S, Jain S, Saha A, et al. Evaluation of glomerular and tubular renal function in neonates with birth asphyxia. Ann Trop Paediatr 2011; 31:129-134.
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19
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Portilla D, Dent C, Sugaya T, et al. Liver fatty acid-binding protein as a biomarker of acute kidney injury after cardiac surgery. Kidney Int 2008; 73:465-472. (Pubitemid 351186293)
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Portilla, D.1
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20
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80052268546
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Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery
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Zappitelli M, Krawczeski CD, Devarajan P, et al. Early postoperative serum cystatin C predicts severe acute kidney injury following pediatric cardiac surgery. Kidney Int 2011; 80:655-662.
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Zappitelli, M.1
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21
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79953864212
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Urine cystatin Cas a biomarker of proximal tubular function immediately after kidney transplantation
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Hall IE, Koyner JL, Doshi MD, et al. Urine cystatin Cas a biomarker of proximal tubular function immediately after kidney transplantation. Am J Nephrol 2011; 33:407-413.
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Am J Nephrol
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Hall, I.E.1
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22
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80052334045
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Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery
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Parikh CR, Devarajan P, Zappitelli M, et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery. J Am Soc Nephrol 2011; 22:1737-1747.
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J Am Soc Nephrol
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23
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Urinary aprotinin as apredictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy
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Nguyen MT, Dent CL, Ross GF, et al. Urinary aprotinin as apredictor of acute kidney injury after cardiac surgery in children receiving aprotinin therapy. Pediatr Nephrol 2008; 23:1317-1326.
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Pediatr Nephrol
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Nguyen, M.T.1
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24
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77749282891
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Urinary netrin-1 isan early predictive biomarker of acute kidney injury after cardiac surgery
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Ramesh G, Krawczeski CD, Woo JG, et al. Urinary netrin-1 isan early predictive biomarker of acute kidney injury after cardiac surgery. Clin J Am Soc Nephrol 2010; 5:395-401.
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Clin J Am Soc Nephrol
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Ramesh, G.1
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Woo, J.G.3
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26
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80051764049
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Baseline values of candidate urine acute kidney injury (AKI) biomarkers vary by gestational age in premature infants
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The study contributes important new data on baseline values of several candidate urinary AKI biomarkers in premature infants of varying gestational ages. It highlights the importance of controlling for gestational age in future studies of these biomarkers in infants with variations in baseline levels likely due to immaturity of renal tubules
-
Askenazi D, Koralkar R, Levitan EB, et al. Baseline values of candidate urine acute kidney injury (AKI) biomarkers vary by gestational age in premature infants. Pediatric Research 2011; 70:302-306. The study contributes important new data on baseline values of several candidate urinary AKI biomarkers in premature infants of varying gestational ages. It highlights the importance of controlling for gestational age in future studies of these biomarkers in infants with variations in baseline levels likely due to immaturity of renal tubules.
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Pediatric Research
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Askenazi, D.1
Koralkar, R.2
Levitan, E.B.3
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27
-
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80755139462
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Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants
-
The first study to evaluate the ability of novel urinary biomarkers to predict AKI in this high-risk group. It evaluated six urinary biomarkers individually and in combination. First study to evaluate the use of osteopontin as a predictor of AKI
-
Askenazi DJ, Montesanti A, Hunley H, et al. Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants. J Pediatr 2011; 159:907-912.e1. The first study to evaluate the ability of novel urinary biomarkers to predict AKI in this high-risk group. It evaluated six urinary biomarkers individually and in combination. First study to evaluate the use of osteopontin as a predictor of AKI.
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(2011)
J Pediatr
, vol.159
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Askenazi, D.J.1
Montesanti, A.2
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28
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Fenoldopam in newborn patients undergoing cardiopulmonary bypass: Controlled clinical trial
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Ricci Z, Stazi GV, Di Chiara L, et al. Fenoldopam in newborn patients undergoing cardiopulmonary bypass: controlled clinical trial. Interact Cardiovasc Thorac Surg 2008; 7:1049-1053.
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29
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High-dose fenoldopam reduces postoperative neutrophil gelatinase-associated lipocaline and cystatin C levels in pediatric cardiac surgery
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Hobbs DJ, Steinke JM, Chung JY, et al. Rasburicase improves hyperuricemia in infants with acute kidney injury. Pediatr Nephrol 2010; 25:305-309.
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