Urinary output and fractional excretion of sodium and urea as indicators of transient versus intrinsic acute kidney injury during early sepsis

Critical Care

Volumn 17, Issue 5, 2013, Pages

  Vanmassenhove, Jill ^a   Glorieux, Griet ^a   Hoste, Eric ^a,b   Dhondt, Annemieke ^a   Vanholder, Raymond ^a   Van Biesen, Wim ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

^b RESEARCH FOUNDATION FLANDERS FWO   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; NEUTROPHIL GELATINASE ASSOCIATED LIPOCALIN; SODIUM; UREA; BIOLOGICAL MARKER;

ACUTE KIDNEY FAILURE; ADULT; ARTICLE; CREATININE BLOOD LEVEL; DIURESIS; END STAGE RENAL DISEASE; FEMALE; GLOMERULUS FILTRATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PREDICTIVE VALUE; PRIORITY JOURNAL; SEPSIS; SODIUM EXCRETION; URINE VOLUME; BLOOD; KIDNEY FUNCTION TEST; MICTURITION; URINALYSIS; URINE;

ACUTE KIDNEY INJURY; BIOLOGICAL MARKERS; CREATININE; FEMALE; HUMANS; KIDNEY FUNCTION TESTS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; SEPSIS; SODIUM; URINALYSIS; URINATION;

EID: 84885365930     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc13057     Document Type: Article

References (39)

1. Bellomo R, Bagshaw S, Langenberg C, Ronco C. Pre-renal azotemia: a flawed paradigm in critically ill septic patients?. Contrib Nephrol 2007, 156:1-9.
2. Bellomo R, Wan L, Langenberg C, May C. Septic acute kidney injury: new concepts. Nephron Exp Nephrol 2008, 109:e95-100. 10.1159/000142933, 18802375.
3. Schrier RW, Wang W. Acute Renal Failure and Sepsis. N Engl J Med 2004, 351:159-169. 10.1056/NEJMra032401, 15247356.
4. Prowle JR, Ishikawa K, May CN, Bellomo R. Renal blood flow during acute renal failure in man. Blood Purif 2009, 28:216-225. 10.1159/000230813, 19648741.
5. Prowle JR, Molan MP, Hornsey E, Bellomo R. Measurement of renal blood flow by phase-contrast magnetic resonance imaging during septic acute kidney injury: a pilot investigation. Critical.Care Medicine 2012, 40(6):1768-76.
6. Wan L, Bagshaw SM, Langenberg C, Saotome T, May C, Bellomo R. Pathophysiology of septic acute kidney injury: what do we really know?. Crit Care Med 2008, 36:S198-S203. 10.1097/CCM.0b013e318168ccd5, 18382194.
7. Langenberg C, Wan L, Egi M, May CN, Bellomo R. Renal blood flow in experimental septic acute renal failure. Kidney Int 2006, 69:1996-2002. 10.1038/sj.ki.5000440, 16641923.
8. Nejat M, Pickering JW, Devarajan P, Bonventre JV, Edelstein CL, Walker RJ, Endre ZH. Some biomarkers of acute kidney injury are increased in pre-renal acute injury. Kidney Int 2012, 81:1254-1262. 10.1038/ki.2012.23, 3365288, 22418979.
9. Doi K, Katagiri D, Negishi K, Hasegawa S, Hamasaki Y, Fujita T, Matsubara T, Ishii T, Yahagi N, Sugaya T, Noiri E. Mild elevation of urinary biomarkers in prerenal acute kidney injury. Kidney Int 2012, 82:1114-1120. 10.1038/ki.2012.266, 22854644.
10. Bouchard J, Soroko SB, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int 2009, 76:422-427. 10.1038/ki.2009.159, 19436332.
11. Schrier RW. Fluid administration in critically ill patients with acute kidney injury. Clin J Am Soc Nephrol 2010, 5:733-739. 10.2215/CJN.00060110, 20167687.
12. Kidney disease: Improving Global Outcomes (KDIGO) Acute Kidney Injury Work Group. KDIGO Clinical Practice Guideline for Acute Kidney Injury. Kidney Int.Suppl 2012, 2:1-138.
13. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care 2004, 8:R204-R212. 10.1186/cc2872, 522841, 15312219.
14. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007, 11:R31. 10.1186/cc5713, 2206446, 17331245.
15. Fliser D, Laville M, Covic A, Fouque D, Vanholder R, Juillard L, Van BW. A European Renal Best Practice (ERBP) position statement on the Kidney Disease Improving Global Outcomes (KDIGO) clinical practice guidelines on acute kidney injury: part 1: definitions, conservative management and contrast-induced nephropathy. Nephrol Dial Transplant 2012, 27:4263-4272. 3520085, 23045432.
16. Macedo E, Malhotra R, Claure-Del GR, Fedullo P, Mehta RL. Defining urine output criterion for acute kidney injury in critically ill patients. Nephrol Dial Transplant 2011, 26:509-515. 10.1093/ndt/gfq332, 3108356, 20562094.
17. American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992, 20:864-874. 10.1097/00003246-199206000-00025, 1597042.
18. Bivet FG. Nonuse of RIFLE classification urine output criteria: biases for acute kidney injury biomarkers performance assessment?. Crit Care Med 2012, 40:1692-1693.
19. Cruz DN, Bolgan I, Perazella MA, Bonello M, de CM, Corradi V, Polanco N, Ocampo C, Nalesso F, Piccinni P, Ronco C. North East Italian Prospective Hospital Renal Outcome Survey on Acute Kidney Injury (NEiPHROS-AKI): targeting the problem with the RIFLE Criteria. Clin J Am Soc Nephrol 2007, 2:418-425. 10.2215/CJN.03361006, 17699446.
20. Joannidis M. Classification of acute kidney injury: are we there yet?. Intensive Care Med 2007, 33:572-574. 10.1007/s00134-007-0536-z, 17310364.
21. Mandelbaum T, Scott DJ, Lee J, Mark RG, Malhotra A, Waikar SS, Howell MD, Talmor D. Outcome of critically ill patients with acute kidney injury using the Acute Kidney Injury Network criteria. Crit Care Med 2011, 39:2659-2664. 3213281, 21765352.
22. Prowle JR, Liu YL, Licari E, Bagshaw SM, Egi M, Haase M, Haase-Fielitz A, Kellum JA, Cruz D, Ronco C, Tsutsui K, Uchino S, Bellomo R. Oliguria as predictive biomarker of acute kidney injury in critically ill patients. Crit Care 2011, 15:R172. 10.1186/cc10318, 3387614, 21771324.
23. Ricci Z, Cruz D, Ronco C. The RIFLE criteria and mortality in acute kidney injury: A systematic review. Kidney Int 2008, 73:538-546. 10.1038/sj.ki.5002743, 18160961.
24. Macedo E, Malhotra R, Bouchard J, Wynn SK, Mehta RL. Oliguria is an early predictor of higher mortality in critically ill patients. Kidney Int 2011, 80:760-767. 10.1038/ki.2011.150, 21716258.
25. Myburgh JA, Finfer S, Bellomo R, Billot L, Cass A, Gattas D, Glass P, Lipman J, Liu B, McArthur C, McGuinness S, Rajbhandari D, Taylor CB, Webb SA. Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Engl J Med 2012, 367:1901-1911. 10.1056/NEJMoa1209759, 23075127.
26. MacLeod A. NCEPOD report on acute kidney injury-must do better. Lancet 2009, 374:1405-1406. 10.1016/S0140-6736(09)61843-2, 19854359.
27. Bagshaw SM, Langenberg C, Bellomo R. Urinary biochemistry and microscopy in septic acute renal failure: a systematic review. Am J Kidney Dis 2006, 48:695-705. 10.1053/j.ajkd.2006.07.017, 17059988.
28. Carvounis CP, Nisar S, Guro-Razuman S. Significance of the fractional excretion of urea in the differential diagnosis of acute renal failure. Kidney Int 2002, 62:2223-2229. 10.1046/j.1523-1755.2002.00683.x, 12427149.
29. Pepin MN, Bouchard J, Legault L, Ethier J. Diagnostic performance of fractional excretion of urea and fractional excretion of sodium in the evaluations of patients with acute kidney injury with or without diuretic treatment. Am J Kidney Dis 2007, 50:566-573. 10.1053/j.ajkd.2007.07.001, 17900456.
30. Bagshaw SM, Haase M, Haase-Fielitz A, Bennett M, Devarajan P, Bellomo R. A prospective evaluation of urine microscopy in septic and non-septic acute kidney injury. Nephrol Dial Transplant 2012, 27:582-588. 10.1093/ndt/gfr331, 21669886.
31. Darmon M, Vincent F, Dellamonica J, Schortgen F, Gonzalez F, Das V, Zeni F, Brochard L, Bernardin G, Cohen Y, Schlemmer B. Diagnostic performance of fractional excretion of urea in the evaluation of critically ill patients with acute kidney injury: a multicenter cohort study. Crit Care 2011, 15:R178. 10.1186/cc10327, 3387621, 21794161.
32. Dewitte A, Biais M, Petit L, Cochard JF, Hilbert G, Combe C, Sztark F. Fractional excretion of urea as a diagnostic index in acute kidney injury in intensive care patients. J Crit Care 2012, 27:505-510. 10.1016/j.jcrc.2012.02.018, 22520491.
33. Vanmassenhove J, Vanholder R, Nagler E, Van BW. Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature. Nephrol Dial Transplant 2013, 28:254-273. 10.1093/ndt/gfs380, 23115326.
34. Bagshaw SM, Bennett M, Haase M, Haase-Fielitz A, Egi M, Morimatsu H, D'Amico G, Goldsmith D, Devarajan P, Bellomo R. Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus non-septic acute kidney injury in critical illness. Intensive Care Med 2010, 36:452-461. 10.1007/s00134-009-1724-9, 19956924.
35. Wheeler DS, Devarajan P, Ma Q, Harmon K, Monaco M, Cvijanovich N, Wong HR. Serum neutrophil gelatinase-associated lipocalin (NGAL) as a marker of acute kidney injury in critically ill children with septic shock. Crit Care Med 2008, 36:1297-1303. 10.1097/CCM.0b013e318169245a, 2757115, 18379258.
36. Martensson J, Bell M, Oldner A, Xu S, Venge P, Martling CR. Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury. Intensive Care Med 2010, 36:1333-1340. 10.1007/s00134-010-1887-4, 20397003.
37. Pedersen SS, Keller AK, Rehling M, Birn H, Jespersen B. NGAL excretion is higher from the healthy side than from the injured side in unilateral acute kidney injury. Scand J Clin Lab Invest 2012, 72:510-512. 10.3109/00365513.2012.692809, 22671281.
38. Hvidberg V, Jacobsen C, Strong RK, Cowland JB, Moestrup SK, Borregaard N. The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake. FEBS Lett 2005, 579:773-777. 10.1016/j.febslet.2004.12.031, 15670845.
39. Paragas N, Qiu A, Zhang Q, Samstein B, Deng SX, Schmidt-Ott KM, Viltard M, Yu W, Forster CS, Gong G, Liu Y, Kulkarni R, Mori K, Kalandadze A, Ratner AJ, Devarajan P, Landry DW, D'Agati V, Lin CS, Barasch J. The Ngal reporter mouse detects the response of the kidney to injury in real time. Nat Med 2011, 17:216-222. 10.1038/nm.2290, 3059503, 21240264.