Serine 707 of APPL1 is Critical for the Synaptic NMDA Receptor-Mediated Akt Phosphorylation Signaling Pathway

Neuroscience Bulletin

Volumn 32, Issue 4, 2016, Pages 323-330

  Wang, Jiejie ^a   Lu, Wen ^a   Chen, Lin ^b   Zhang, Ping ^c   Qian, Tingting ^c   Cao, Wei ^a   Luo, Jianhong ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Akt; APPL1; Neuroprotection; NMDA receptors; PSD95

Indexed keywords

ADAPTOR PROTEIN CONTAINING PLECKSTRIN HOMOLOGY DOMAIN PHOSPHOTYROSINE BINDING DOMAIN AND LEUCINE ZIPPER MOTIF; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE B; SERINE; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; APPL1 PROTEIN, HUMAN; BICUCULLINE; DLG4 PROTEIN, HUMAN; FAMPRIDINE; MEMBRANE PROTEIN; ONCOPROTEIN; POTASSIUM CHANNEL BLOCKING AGENT; SIGNAL PEPTIDE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HIPPOCAMPAL NEURONAL CULTURE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; NEUROPROTECTION; NONHUMAN; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SYNAPSE; WESTERN BLOTTING; ANIMAL; BRAIN; C57BL MOUSE; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; MALE; MAMMALIAN EMBRYO; METABOLISM; MOUSE; NERVE CELL; NEWBORN; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

4-AMINOPYRIDINE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANIMALS, NEWBORN; BICUCULLINE; BRAIN; CELLS, CULTURED; EMBRYO, MAMMALIAN; GABA ANTAGONISTS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; NEURONS; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; POTASSIUM CHANNEL BLOCKERS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; SERINE; SIGNAL TRANSDUCTION;

EID: 84974851680     PISSN: 16737067     EISSN: 19958218     Source Type: Journal    
DOI: 10.1007/s12264-016-0042-9     Document Type: Article

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