The cytoprotective effect of isorhamnetin against oxidative stress is mediated by the upregulation of the Nrf2-dependent HO-1 expression in C2C12 myoblasts through scavenging reactive oxygen species and ERK inactivation

General Physiology and Biophysics

Volumn 35, Issue 2, 2016, Pages 145-154

  Choi, Yung Hyun ^a  

^a Dong Eui University   (South Korea)

Author keywords

DNA damage; ERK; Isorhamnetin; Nrf2 HO 1; ROS

Indexed keywords

ACTIN; HEME OXYGENASE 1; HISTONE H2AX; HYDROGEN PEROXIDE; ISORHAMNETIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR NRF2; 3-METHYLQUERCETIN; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; NFE2L2 PROTEIN, MOUSE; QUERCETIN; SCAVENGER; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; CYTOPROTECTIVE AGENT; PROTEIN KINASE B;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL VIABILITY; COMET ASSAY; CYTOTOXICITY; DNA DAMAGE; ELECTROPHORESIS; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; IN VITRO STUDY; MOUSE; MYOBLAST; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; COMPETITIVE INHIBITION; CONTROLLED STUDY; GENE SILENCING; MTT ASSAY; PROTEIN PHOSPHORYLATION; TRANSIENT TRANSFECTION;

ANIMALS; CELL LINE; CELL SURVIVAL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; HEME OXYGENASE-1; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE; MYOBLASTS; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; QUERCETIN; REACTIVE OXYGEN SPECIES; UP-REGULATION;

EID: 84974845965     PISSN: 02315882     EISSN: 13384325     Source Type: Journal    
DOI: 10.4149/gpb_2015034     Document Type: Article

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