Isorhamnetin inhibits H 2O 2-induced activation of the intrinsic apoptotic pathway in H9c2 cardiomyocytes through scavenging reactive oxygen species and ERK inactivation

Journal of Cellular Biochemistry

Volumn 113, Issue 2, 2012, Pages 473-485

  Sun, Bing ^a   Sun, Gui Bo ^a   Xiao, Jing ^a   Chen, Rong Chang ^a   Wang, Xin ^a   Wu, Ying ^a   Cao, Li ^a   Yang, Zhi Hong ^a   Sun, Xiao Bo ^a  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

Author keywords

Extracellular signal regulated kinase; Flavonol; Isorhamnetin; Myocardial apoptosis; Reactive oxygen species

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; CASPASE 8; FAS ANTIGEN; HYDROGEN PEROXIDE; ISORHAMNETIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR RECEPTOR 1;

APOPTOSIS; ARTICLE; DOWN REGULATION; GENE OVEREXPRESSION; HEART MUSCLE CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; CATALASE; CELL LINE; CELL SURVIVAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; GENES, BCL-2; HYDROGEN PEROXIDE; L-LACTATE DEHYDROGENASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA, HEART; MYOCYTES, CARDIAC; PROTEIN KINASE INHIBITORS; QUERCETIN; RATS; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

HIPPOPHAE RHAMNOIDES; RHAMNACEAE;

EID: 84862908562     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.23371     Document Type: Article

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