Dendritic cells guide islet autoimmunity through a restricted and uniquely processed peptidome presented by high-risk HLA-DR

Journal of Immunology

Volumn 196, Issue 8, 2016, Pages 3253-3263

  Van Lummel, Menno ^a   Van Veelen, Peter A ^a   De Ru, Arnoud H ^a   Janssen, George M C ^a   Pool, Jos ^a   Laban, Sandra ^a   Joosten, Antoinette M ^a   Nikolic, Tatjana ^a   Drijfhout, Jan W ^a   Mearin, M Luisa ^a   Aanstoot, Henk J ^b   Peakman, Mark ^c   Roep, Bart O ^a,d  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b Diabeter   (Netherlands)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; GLUTAMATE DECARBOXYLASE 65; HLA A2 ANTIGEN; HLA DR ANTIGEN; HLA DR3 ANTIGEN; HLA DR4 ANTIGEN; IA 2 PROTEIN; PANCREAS ISLET CELL ANTIBODY; PREPROINSULIN; PROTEOME; SIGNAL PEPTIDE; TUMOR ANTIGEN; UNCLASSIFIED DRUG; AUTOANTIGEN; EPITOPE; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 2; INSULIN; PROTEIN BINDING; PROTEIN PRECURSOR; PTPRN PROTEIN, HUMAN; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE;

ANTIGEN BINDING; ANTIGEN PRESENTATION; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOGENICITY; INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET; PRIORITY JOURNAL; PROTEIN BINDING; RISK ASSESSMENT; CELL CULTURE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM;

AUTOANTIGENS; AUTOIMMUNITY; B-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DENDRITIC CELLS; DIABETES MELLITUS, TYPE 1; EPITOPES, T-LYMPHOCYTE; GLUTAMATE DECARBOXYLASE; HLA-DR3 ANTIGEN; HLA-DR4 ANTIGEN; HUMANS; INSULIN; ISLETS OF LANGERHANS; LYMPHOCYTE ACTIVATION; PROTEIN BINDING; PROTEIN PRECURSORS; RECEPTOR-LIKE PROTEIN TYROSINE PHOSPHATASES, CLASS 8;

EID: 84974832027     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1501282     Document Type: Article

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