Humoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetes

Endocrinology

Volumn 151, Issue 6, 2010, Pages 2528-2537

  Morran, Michael P ^a   Casu, Anna ^c   Arena, Vincent C ^d   Pietropaolo, Susan ^a   Zhang, Ying Jian ^a   Satin, Leslie S ^b   Nelson, Patrick ^b   Omenn, Gilbert S ^b   Trucco, Massimo ^c   Becker, Dorothy J ^c   Pietropaolo, Massimo ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^d UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIGEN IA 2; AUTOANTIBODY; AUTOANTIGEN; EPITOPE; GLUTAMATE DECARBOXYLASE; INSULIN; INSULIN ANTIBODY; PANCREAS ISLET CELL ANTIBODY; PROTEIN TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG; ICA512 AUTOANTIBODY; RECOMBINANT PROTEIN;

ADOLESCENT; ADULT; AGED; ANTIBODY RESPONSE; ARTICLE; AUTOIMMUNITY; BINDING COMPETITION; CHILD; CONTROLLED STUDY; DIABETIC PATIENT; DISEASE COURSE; FEMALE; HUMAN; HUMORAL IMMUNITY; IMMUNOPRECIPITATION; IMMUNOTHERAPY; IMPAIRED GLUCOSE TOLERANCE; INFANT; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NEUROENDOCRINE SYSTEM; PATHOGENESIS; PEDIATRIC HOSPITAL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN DOMAIN; RISK FACTOR; SCHOOL CHILD; GENETICS; IMMUNOLOGY; METABOLISM; MIDDLE AGED;

ADOLESCENT; ADULT; AGED; AUTOANTIBODIES; AUTOANTIGENS; AUTOIMMUNITY; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; IMMUNITY, HUMORAL; IMMUNOPRECIPITATION; INFANT; MALE; MIDDLE AGED; RECOMBINANT PROTEINS; YOUNG ADULT;

EID: 77954532446     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1257     Document Type: Article

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