메뉴 건너뛰기




Volumn 30, Issue 1, 2016, Pages 428-440

Parathyroid hormone 1 receptor is essential to induce FGF23 production and maintain systemic mineral ion homeostasis

Author keywords

Calcium phosphate metabolism; Galnt3; Kidney bone mineral diseases

Indexed keywords

FIBROBLAST GROWTH FACTOR 23; MESSENGER RNA; PARATHYROID HORMONE RECEPTOR 1; PHOSPHATE; BETA GLUCURONIDASE; CALBINDIN; CALCIUM; FIBROBLAST GROWTH FACTOR; KLOTHO PROTEIN; N ACETYLGALACTOSAMINYLTRANSFERASE; NR4A2 PROTEIN, MOUSE; NUCLEAR RECEPTOR RELATED FACTOR 1; POLYPEPTIDE N-ACETYLGALACTOSAMINYLTRANSFERASE;

EID: 84974816061     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-278184     Document Type: Article
Times cited : (53)

References (47)
  • 1
    • 76149097543 scopus 로고    scopus 로고
    • Calcium metabolism in health and disease
    • Peacock, M. (2010) Calcium metabolism in health and disease. Clin. J. Am. Soc. Nephrol. 5(Suppl 1), S23-S30
    • (2010) Clin. J. Am. Soc. Nephrol. , vol.5 , pp. S23-S30
    • Peacock, M.1
  • 2
    • 84858331254 scopus 로고    scopus 로고
    • Calcium and phosphate homeostasis: Concerted interplay of new regulators
    • Civitelli, R., and Ziambaras, K. (2011) Calcium and phosphate homeostasis: concerted interplay of new regulators. J. Endocrinol. Invest. 34(7, Suppl), 3-7
    • (2011) J. Endocrinol. Invest. , vol.34 , Issue.7 , pp. 3-7
    • Civitelli, R.1    Ziambaras, K.2
  • 3
    • 13444260744 scopus 로고    scopus 로고
    • Parathyroid hormone secretion and action: Evidence for discrete receptors for the carboxyl-terminal region and related biological actions of carboxyl-terminal ligands
    • Murray, T. M., Rao, L. G., Divieti, P., and Bringhurst, F. R. (2005) Parathyroid hormone secretion and action: evidence for discrete receptors for the carboxyl-terminal region and related biological actions of carboxyl-terminal ligands. Endocr. Rev. 26, 78-113
    • (2005) Endocr. Rev. , vol.26 , pp. 78-113
    • Murray, T.M.1    Rao, L.G.2    Divieti, P.3    Bringhurst, F.R.4
  • 4
    • 0035405802 scopus 로고    scopus 로고
    • Molecular properties of the PTH/PTHrP receptor
    • Gardella, T. J., and Jüppner, H. (2001) Molecular properties of the PTH/PTHrP receptor. Trends Endocrinol. Metab. 12, 210-217
    • (2001) Trends Endocrinol. Metab. , vol.12 , pp. 210-217
    • Gardella, T.J.1    Jüppner, H.2
  • 9
    • 0031442990 scopus 로고    scopus 로고
    • Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide
    • Schipani, E., Lanske, B., Hunzelman, J., Luz, A., Kovacs, C. S., Lee, K., Pirro, A., Kronenberg, H. M., and Jüppner, H. (1997) Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide. Proc. Natl. Acad. Sci. USA 94, 13689-13694
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13689-13694
    • Schipani, E.1    Lanske, B.2    Hunzelman, J.3    Luz, A.4    Kovacs, C.S.5    Lee, K.6    Pirro, A.7    Kronenberg, H.M.8    Jüppner, H.9
  • 10
    • 0036696005 scopus 로고    scopus 로고
    • The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C
    • Guo, J., Chung, U. I., Kondo, H., Bringhurst, F. R., and Kronenberg, H. M. (2002) The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C. Dev. Cell 3, 183-194
    • (2002) Dev. Cell , vol.3 , pp. 183-194
    • Guo, J.1    Chung, U.I.2    Kondo, H.3    Bringhurst, F.R.4    Kronenberg, H.M.5
  • 11
    • 79953701946 scopus 로고    scopus 로고
    • Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses
    • Powell, W. F., Jr., Barry, K. J., Tulum, I., Kobayashi, T., Harris, S. E., Bringhurst, F. R., and Pajevic, P. D. (2011) Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J. Endocrinol. 209, 21-32
    • (2011) J. Endocrinol. , vol.209 , pp. 21-32
    • Powell, W.F.1    Barry, K.J.2    Tulum, I.3    Kobayashi, T.4    Harris, S.E.5    Bringhurst, F.R.6    Pajevic, P.D.7
  • 13
    • 33748752139 scopus 로고    scopus 로고
    • Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor
    • Bounoutas, G. S., Tawfeek, H., Fröhlich, L. F., Chung, U. I., and Abou-Samra, A. B. (2006) Impact of impaired receptor internalization on calcium homeostasis in knock-in mice expressing a phosphorylation-deficient parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology 147, 4674-4679
    • (2006) Endocrinology , vol.147 , pp. 4674-4679
    • Bounoutas, G.S.1    Tawfeek, H.2    Fröhlich, L.F.3    Chung, U.I.4    Abou-Samra, A.B.5
  • 14
    • 0035206838 scopus 로고    scopus 로고
    • Partial rescue of PTH/PTHrP receptor knockout mice by targeted expression of the Jansen transgene
    • Soegiarto, D. W., Kiachopoulos, S., Schipani, E., Jüppner, H., Erben, R. G., and Lanske, B. (2001) Partial rescue of PTH/PTHrP receptor knockout mice by targeted expression of the Jansen transgene. Endocrinology 142, 5303-5310
    • (2001) Endocrinology , vol.142 , pp. 5303-5310
    • Soegiarto, D.W.1    Kiachopoulos, S.2    Schipani, E.3    Jüppner, H.4    Erben, R.G.5    Lanske, B.6
  • 16
  • 19
    • 0035032073 scopus 로고    scopus 로고
    • Phosphate wasting in oncogenic osteomalacia: PHEX is normal and the tumor-derived factor has unique properties
    • Nelson, A. E., Hogan, J. J., Holm, I. A., Robinson, B. G., and Mason, R. S. (2001) Phosphate wasting in oncogenic osteomalacia: PHEX is normal and the tumor-derived factor has unique properties. Bone 28, 430-439
    • (2001) Bone , vol.28 , pp. 430-439
    • Nelson, A.E.1    Hogan, J.J.2    Holm, I.A.3    Robinson, B.G.4    Mason, R.S.5
  • 20
    • 80052303008 scopus 로고    scopus 로고
    • Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo
    • Rhee, Y., Bivi, N., Farrow, E., Lezcano, V., Plotkin, L. I., White, K. E., and Bellido, T. (2011) Parathyroid hormone receptor signaling in osteocytes increases the expression of fibroblast growth factor-23 in vitro and in vivo. Bone 49, 636-643
    • (2011) Bone , vol.49 , pp. 636-643
    • Rhee, Y.1    Bivi, N.2    Farrow, E.3    Lezcano, V.4    Plotkin, L.I.5    White, K.E.6    Bellido, T.7
  • 21
    • 34948866160 scopus 로고    scopus 로고
    • Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism
    • Kawata, T., Imanishi, Y., Kobayashi, K., Miki, T., Arnold, A., Inaba, M., and Nishizawa, Y. (2007) Parathyroid hormone regulates fibroblast growth factor-23 in a mouse model of primary hyperparathyroidism. J. Am. Soc. Nephrol. 18, 2683-2688
    • (2007) J. Am. Soc. Nephrol , vol.18 , pp. 2683-2688
    • Kawata, T.1    Imanishi, Y.2    Kobayashi, K.3    Miki, T.4    Arnold, A.5    Inaba, M.6    Nishizawa, Y.7
  • 22
    • 84964267910 scopus 로고    scopus 로고
    • Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription
    • Meir, T., Durlacher, K., Pan, Z., Amir, G., Richards, W. G., Silver, J., and Naveh-Many, T. (2014) Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription. Kidney Int. 86, 1106-1115
    • (2014) Kidney Int. , vol.86 , pp. 1106-1115
    • Meir, T.1    Durlacher, K.2    Pan, Z.3    Amir, G.4    Richards, W.G.5    Silver, J.6    Naveh-Many, T.7
  • 23
    • 84926021852 scopus 로고    scopus 로고
    • Molecular interactions of FGF23 and PTH in phosphate regulation
    • Lanske, B., and Razzaque, M. S. (2014) Molecular interactions of FGF23 and PTH in phosphate regulation. Kidney Int. 86, 1072-1074
    • (2014) Kidney Int. , vol.86 , pp. 1072-1074
    • Lanske, B.1    Razzaque, M.S.2
  • 24
    • 0036076389 scopus 로고    scopus 로고
    • Expression of Cre Recombinasein the developing mouse limb bud driven by a Prxl enhancer
    • Logan, M., Martin, J. F., Nagy, A., Lobe, C., Olson, E. N., and Tabin, C. J. (2002) Expression of Cre Recombinasein the developing mouse limb bud driven by a Prxl enhancer. Genesis 33, 77-80
    • (2002) Genesis , vol.33 , pp. 77-80
    • Logan, M.1    Martin, J.F.2    Nagy, A.3    Lobe, C.4    Olson, E.N.5    Tabin, C.J.6
  • 25
    • 0019126423 scopus 로고
    • Differential staining of cartilage and bone in whole mouse fetuses by Alcian blue and alizarin red S
    • McLeod, M. J. (1980) Differential staining of cartilage and bone in whole mouse fetuses by Alcian blue and alizarin red S. Teratology 22, 299-301
    • (1980) Teratology , vol.22 , pp. 299-301
    • McLeod, M.J.1
  • 29
    • 0141844575 scopus 로고    scopus 로고
    • Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX
    • Liu, S., Guo, R., Simpson, L. G., Xiao, Z. S., Burnham, C. E., and Quarles, L. D. (2003) Regulation of fibroblastic growth factor 23 expression but not degradation by PHEX. J. Biol. Chem. 278, 37419-37426
    • (2003) J. Biol. Chem. , vol.278 , pp. 37419-37426
    • Liu, S.1    Guo, R.2    Simpson, L.G.3    Xiao, Z.S.4    Burnham, C.E.5    Quarles, L.D.6
  • 31
    • 0032574725 scopus 로고    scopus 로고
    • Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities
    • Beck, L., Karaplis, A. C., Amizuka, N., Hewson, A. S., Ozawa, H., and Tenenhouse, H. S. (1998) Targeted inactivation of Npt2 in mice leads to severe renal phosphate wasting, hypercalciuria, and skeletal abnormalities. Proc. Natl. Acad. Sci. USA 95, 5372-5377
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5372-5377
    • Beck, L.1    Karaplis, A.C.2    Amizuka, N.3    Hewson, A.S.4    Ozawa, H.5    Tenenhouse, H.S.6
  • 32
    • 80051979062 scopus 로고    scopus 로고
    • FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH
    • Yuan, Q., Sato, T., Densmore, M., Saito, H., Schüler, C., Erben, R. G., and Lanske, B. (2011) FGF-23/Klotho signaling is not essential for the phosphaturic and anabolic functions of PTH. J. Bone Miner. Res. 26, 2026-2035
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 2026-2035
    • Yuan, Q.1    Sato, T.2    Densmore, M.3    Saito, H.4    Schüler, C.5    Erben, R.G.6    Lanske, B.7
  • 33
    • 0032717355 scopus 로고    scopus 로고
    • Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development
    • Lanske, B., Amling, M., Neff, L., Guiducci, J., Baron, R., and Kronenberg, H. M. (1999) Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development. J. Clin. Invest. 104, 399-407
    • (1999) J. Clin. Invest. , vol.104 , pp. 399-407
    • Lanske, B.1    Amling, M.2    Neff, L.3    Guiducci, J.4    Baron, R.5    Kronenberg, H.M.6
  • 34
    • 0028943780 scopus 로고
    • A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia
    • Schipani, E., Kruse, K., and Jüppner, H. (1995) A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia. Science 268, 98-100
    • (1995) Science , vol.268 , pp. 98-100
    • Schipani, E.1    Kruse, K.2    Jüppner, H.3
  • 35
    • 0032128253 scopus 로고    scopus 로고
    • Absence of functional receptors for parathyroid hormone and parathyroid hormone-related peptide in Blomstrand chondrodysplasia
    • Jobert, A. S., Zhang, P., Couvineau, A., Bonaventure, J., Roume, J., Le Merrer, M., and Silve, C. (1998) Absence of functional receptors for parathyroid hormone and parathyroid hormone-related peptide in Blomstrand chondrodysplasia. J. Clin. Invest. 102, 34-40
    • (1998) J. Clin. Invest. , vol.102 , pp. 34-40
    • Jobert, A.S.1    Zhang, P.2    Couvineau, A.3    Bonaventure, J.4    Roume, J.5    Le Merrer, M.6    Silve, C.7
  • 36
    • 0031725947 scopus 로고    scopus 로고
    • Inactivating mutation in the human parathyroid hormone receptor type 1 gene in Blomstrand chondrodysplasia
    • Karaplis, A. C., He, B., Nguyen, M. T., Young, I. D., Semeraro, D., Ozawa, H., and Amizuka, N. (1998) Inactivating mutation in the human parathyroid hormone receptor type 1 gene in Blomstrand chondrodysplasia. Endocrinology 139, 5255-5258
    • (1998) Endocrinology , vol.139 , pp. 5255-5258
    • Karaplis, A.C.1    He, B.2    Nguyen, M.T.3    Young, I.D.4    Semeraro, D.5    Ozawa, H.6    Amizuka, N.7
  • 37
    • 33947537963 scopus 로고    scopus 로고
    • Update in osteoporosis and metabolic bone disorders
    • Shoback, D. (2007) Update in osteoporosis and metabolic bone disorders. J. Clin. Endocrinol. Metab. 92, 747-753
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 747-753
    • Shoback, D.1
  • 38
    • 0025908905 scopus 로고
    • Hypercalcemia of malignancy: Pathophysiology, diagnosis and treatment
    • Mosekilde, L., Eriksen, E. F., and Charles, P. (1991) Hypercalcemia of malignancy: pathophysiology, diagnosis and treatment. Crit. Rev. Oncol. Hematol. 11, 1-27
    • (1991) Crit. Rev. Oncol. Hematol. , vol.11 , pp. 1-27
    • Mosekilde, L.1    Eriksen, E.F.2    Charles, P.3
  • 40
    • 0029750190 scopus 로고    scopus 로고
    • Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein
    • Vortkamp, A., Lee, K., Lanske, B., Segre, G. V., Kronenberg, H. M., and Tabin, C. J. (1996) Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science 273, 613-622
    • (1996) Science , vol.273 , pp. 613-622
    • Vortkamp, A.1    Lee, K.2    Lanske, B.3    Segre, G.V.4    Kronenberg, H.M.5    Tabin, C.J.6
  • 41
    • 64149087364 scopus 로고    scopus 로고
    • Active Ca(2+) reabsorption in the connecting tubule
    • Boros, S., Bindels, R. J., and Hoenderop, J. G. (2009) Active Ca(2+) reabsorption in the connecting tubule. Pflugers Arch. 458, 99-109
    • (2009) Pflugers Arch. , vol.458 , pp. 99-109
    • Boros, S.1    Bindels, R.J.2    Hoenderop, J.G.3
  • 43
    • 33750203846 scopus 로고    scopus 로고
    • Proximal tubular handling of phosphate: A molecular perspective
    • Forster, I. C., Hernando, N., Biber, J., and Murer, H. (2006) Proximal tubular handling of phosphate: a molecular perspective. Kidney Int. 70, 1548-1559
    • (2006) Kidney Int. , vol.70 , pp. 1548-1559
    • Forster, I.C.1    Hernando, N.2    Biber, J.3    Murer, H.4
  • 44
    • 58149394434 scopus 로고    scopus 로고
    • Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasia
    • Brown, W. W., Jüppner, H., Langman, C. B., Price, H., Farrow, E. G., White, K. E., and McCormick, K. L. (2009) Hypophosphatemia with elevations in serum fibroblast growth factor 23 in a child with Jansen's metaphyseal chondrodysplasia. J. Clin. Endocrinol. Metab. 94, 17-20
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 17-20
    • Brown, W.W.1    Jüppner, H.2    Langman, C.B.3    Price, H.4    Farrow, E.G.5    White, K.E.6    McCormick, K.L.7
  • 46
    • 77957993384 scopus 로고    scopus 로고
    • PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: A bone parathyroid feedback loop
    • Lavi-Moshayoff, V., Wasserman, G., Meir, T., Silver, J., and Naveh-Many, T. (2010) PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: a bone parathyroid feedback loop. Am. J. Physiol. Renal Physiol. 299, F882-F889
    • (2010) Am. J. Physiol. Renal Physiol. , vol.299 , pp. F882-F889
    • Lavi-Moshayoff, V.1    Wasserman, G.2    Meir, T.3    Silver, J.4    Naveh-Many, T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.