The genome project-write we need technology and an ethical framework for genome-scale engineering

Science

Volumn 353, Issue 6295, 2016, Pages 126-127

  Boeke, Jef D ^a   Church, George ^a   Hessel, Andrew ^a   Kelley, Nancy J ^a   Arkin, Adam ^a   Cai, Yizhi ^a   Carlson, Rob ^a   Chakravarti, Aravinda ^a   Cornish, Virginia W ^a   Holt, Liam ^a   Isaacs, Farren J ^a   Kuiken, Todd ^a   Lajoie, Marc ^a   Lessor, Tracy ^a   Lunshof, Jeantine ^a   Maurano, Matthew T ^a   Mitchell, Leslie A ^a   Rine, Jasper ^a   Rosser, Susan ^a   Sanjana, Neville E ^a   Silver, Pamela A ^a   Valle, David ^a   Wang, Harris ^a   Way, Jeffrey C ^a   Yang, Luhan ^a   more..

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GENETIC ANALYSIS; GENETIC ENGINEERING; GENOME; PROJECT ASSESSMENT; RESEARCH METHOD; TECHNOLOGICAL DEVELOPMENT;

GENE EXPRESSION; GENE SEQUENCE; GENETIC ENGINEERING; HUMAN; HUMAN GENOME PROJECT; PRIORITY JOURNAL; REVIEW; SEQUENCE ANALYSIS; ETHICS; HUMAN GENOME; ORGANIZATION AND MANAGEMENT; POLICY; PROCEDURES; TRENDS;

GENETIC ENGINEERING; GENOME, HUMAN; HUMAN GENOME PROJECT; HUMANS; POLICY;

EID: 84974674507     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaf6850     Document Type: Review

References (16)

1. International Human Genome Sequencing Consortium, Nature 431, 931 (2004).
2. C. W. Fuller et al., Nat. Biotechnol. 27, 1013 (2009).
3. L. Cong et al., Science 339, 819 (2013).
4. P. Mali et al., Science 339, 823 (2013).
5. A. D. Haimovich, P. Muir, F. J. Isaacs, Nat. Rev. Genet. 16, 501 (2015).
6. D. Baltimore et al., Science 348, 36 (2015).
7. Presidential Commission for the Study of Bioethical Issues, New Directions: The Ethics of Synthetic Biology and Emerging Technologies (Washington, DC, 2010).
8. J. Kimmelman et al., Nature 533, 311 (2016).
9. P. A. Carr, G. M. Church, Nat. Biotechnol. 27, 1151 (2009).
10. J. Cello, A. V. Paul, E. Wimmer, Science 297, 1016 (2002).
11. D. G. Gibson et al., Science 329, 52 (2010).
12. M. J. Lajoie et al., Science 342, 357 (2013).
13. F. J. Isaacs et al., Science 333, 348 (2011).
14. N. Annaluru et al., Science 344, 55 (2014).
15. J. S. Dymond et al., Nature 477, 471 (2011).
16. K. Takahashi, S. Yamanaka, Cell 126, 663 (2006).