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Volumn 111, Issue , 2016, Pages 43-57

Combined therapy using bevacizumab and turmeric ethanolic extract (with absorbable curcumin) exhibited beneficial efficacy in colon cancer mice

Author keywords

Bevacizumab; Colorectal cancer; Curcumin; Turmeric; Turmerone

Indexed keywords

BEVACIZUMAB; CURCUMIN; FLUOROURACIL; FOLINIC ACID; OXALIPLATIN; TURMERIC; TURMERONE; ALCOHOL; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; PLANT EXTRACT; SOLVENT; TURMERIC EXTRACT;

EID: 84974593776     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2016.05.025     Document Type: Article
Times cited : (48)

References (43)
  • 1
    • 77954251791 scopus 로고    scopus 로고
    • GLOBOCAN (accessed 01.11.15)
    • GLOBOCAN Cancer Fact Sheets 2015 (accessed 01.11.15) http://globocan.iarc.fr/Pages/fact-sheets-cancer.aspx
    • (2015) Cancer Fact Sheets
  • 2
    • 33646028804 scopus 로고    scopus 로고
    • Molecular targets of dietary agents for prevention and therapy of cancer
    • B.B. Aggarwal, and S. Shishodia Molecular targets of dietary agents for prevention and therapy of cancer Biochem. Pharmacol. 71 2006 1397 1421
    • (2006) Biochem. Pharmacol. , vol.71 , pp. 1397-1421
    • Aggarwal, B.B.1    Shishodia, S.2
  • 3
    • 0033161171 scopus 로고    scopus 로고
    • Epidemiology of digestive tract cancers in India. V. Large and small bowel
    • K.M. Mohandas, and D.C. Desai Epidemiology of digestive tract cancers in India. V. Large and small bowel Indian J. Gastroenterol. 18 1999 118 121
    • (1999) Indian J. Gastroenterol. , vol.18 , pp. 118-121
    • Mohandas, K.M.1    Desai, D.C.2
  • 4
    • 0035988602 scopus 로고    scopus 로고
    • Chemotherapeutic potential of curcumin for colorectal cancer
    • D.P. Chauhan Chemotherapeutic potential of curcumin for colorectal cancer Curr. Pharm. Des. 8 2002 1695 1706
    • (2002) Curr. Pharm. Des. , vol.8 , pp. 1695-1706
    • Chauhan, D.P.1
  • 6
    • 84893973489 scopus 로고    scopus 로고
    • Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: The golden pigment from golden spice
    • S. Prasad, A.K. Tyagi, and B.B. Aggarwal Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spice Cancer Res. Treat. 46 2014 2 18
    • (2014) Cancer Res. Treat. , vol.46 , pp. 2-18
    • Prasad, S.1    Tyagi, A.K.2    Aggarwal, B.B.3
  • 8
    • 12844277237 scopus 로고    scopus 로고
    • Consumption of the putative chemopreventive agent curcumin by cancer patients: Assessment of curcumin levels in the colorectum and their pharmacodynamic consequences
    • G. Garcea, D.P. Berry, D.J. Jones, R. Singh, and et al. Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences Cancer Epidemiol. Biomarkers Prev. 14 2005 120 125
    • (2005) Cancer Epidemiol. Biomarkers Prev. , vol.14 , pp. 120-125
    • Garcea, G.1    Berry, D.P.2    Jones, D.J.3    Singh, R.4
  • 9
    • 84871971567 scopus 로고    scopus 로고
    • Therapeutic roles of curcumin: Lessons learned from clinical trials
    • S.C. Gupta, S. Patchva, and B.B. Aggarwal Therapeutic roles of curcumin: lessons learned from clinical trials AAPS J. 15 2013 195 218
    • (2013) AAPS J. , vol.15 , pp. 195-218
    • Gupta, S.C.1    Patchva, S.2    Aggarwal, B.B.3
  • 10
    • 58149084882 scopus 로고    scopus 로고
    • A pilot cross-over study to evaluate human oral bioavailability of BCM-95CG (Biocurcumax). A novel bioenhanced preparation of curcumin
    • B. Antony, B. Merina, V.S. Iyer, N. Judy, and et al. A pilot cross-over study to evaluate human oral bioavailability of BCM-95CG (Biocurcumax). a novel bioenhanced preparation of curcumin J. Pharm. Sci. 70 2008 445 449
    • (2008) J. Pharm. Sci. , vol.70 , pp. 445-449
    • Antony, B.1    Merina, B.2    Iyer, V.S.3    Judy, N.4
  • 11
    • 84883346712 scopus 로고    scopus 로고
    • Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: Identification of novel components of turmeric
    • B.B. Aggarwal, W. Yuan, S. Li, and S.C. Gupta Curcumin-free turmeric exhibits anti-inflammatory and anticancer activities: identification of novel components of turmeric Mol. Nutr. Food Res. 57 2013 1529 1542
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1529-1542
    • Aggarwal, B.B.1    Yuan, W.2    Li, S.3    Gupta, S.C.4
  • 12
    • 84863262829 scopus 로고    scopus 로고
    • The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells
    • G.G.L. Yue, S.W. Cheng, H. Yu, Z.S. Xu, and et al. The role of turmerones on curcumin transportation and P-glycoprotein activities in intestinal Caco-2 cells J. Med. Food 15 2012 242 252
    • (2012) J. Med. Food , vol.15 , pp. 242-252
    • Yue, G.G.L.1    Cheng, S.W.2    Yu, H.3    Xu, Z.S.4
  • 13
    • 84958818529 scopus 로고    scopus 로고
    • Turmeric ethanolic extract possesses stronger inhibitory activities on colon tumor growth than curcumin - The importance of turmerones
    • G.G.L. Yue, L. Jiang, H.F. Kwok, J.K.M. Lee, and et al. Turmeric ethanolic extract possesses stronger inhibitory activities on colon tumor growth than curcumin - the importance of turmerones J. Funct. Foods 22 2016 565 577
    • (2016) J. Funct. Foods , vol.22 , pp. 565-577
    • Yue, G.G.L.1    Jiang, L.2    Kwok, H.F.3    Lee, J.K.M.4
  • 14
    • 77953272360 scopus 로고    scopus 로고
    • Elimination of colon cancer stem-like cells by the combination of curcumin and FOLFOX
    • Y. Yu, S.S. Kanwar, B.B. Patel, J. Nautiyal, and et al. Elimination of colon cancer stem-like cells by the combination of curcumin and FOLFOX Trans. Oncol. 2 2009 321 328
    • (2009) Trans. Oncol. , vol.2 , pp. 321-328
    • Yu, Y.1    Kanwar, S.S.2    Patel, B.B.3    Nautiyal, J.4
  • 15
    • 79952419581 scopus 로고    scopus 로고
    • Systemic therapy for metastatic colorectal cancer: Patterns of chemotherapy and biologic therapy use in US medical oncology practice
    • G.P. Hess, P.F. Wang, D. Quach, B. Barber, and Z. Zhao Systemic therapy for metastatic colorectal cancer: patterns of chemotherapy and biologic therapy use in US medical oncology practice J. Oncol. Pract. 6 2010 301 307
    • (2010) J. Oncol. Pract. , vol.6 , pp. 301-307
    • Hess, G.P.1    Wang, P.F.2    Quach, D.3    Barber, B.4    Zhao, Z.5
  • 16
    • 74949092100 scopus 로고    scopus 로고
    • Longitudinal patterns of chemotherapy use in metastatic colorectal cancer
    • S.Y. Zafar, J.E. Marcello, J.L. Wheeler, K.L. Rowe, and et al. Longitudinal patterns of chemotherapy use in metastatic colorectal cancer J. Oncol. Pract. 5 2009 228 233
    • (2009) J. Oncol. Pract. , vol.5 , pp. 228-233
    • Zafar, S.Y.1    Marcello, J.E.2    Wheeler, J.L.3    Rowe, K.L.4
  • 17
    • 84892595053 scopus 로고    scopus 로고
    • Differential therapeutic effects of anti-VEGF-A antibody in different tumor models: Implications for choosing appropriate tumor models for drug testing
    • D. Alishekevitz, R. Bril, D. Loven, V. Miller, and et al. Differential therapeutic effects of anti-VEGF-A antibody in different tumor models: implications for choosing appropriate tumor models for drug testing Mol. Cancer Ther. 13 2014 202 213
    • (2014) Mol. Cancer Ther. , vol.13 , pp. 202-213
    • Alishekevitz, D.1    Bril, R.2    Loven, D.3    Miller, V.4
  • 18
    • 77950528228 scopus 로고    scopus 로고
    • Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R
    • B.B. Patel, D. Gupta, A.A. Elliott, V. Sengupta, and et al. Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R Anticancer Res. 30 2010 319 325
    • (2010) Anticancer Res. , vol.30 , pp. 319-325
    • Patel, B.B.1    Gupta, D.2    Elliott, A.A.3    Sengupta, V.4
  • 19
    • 34248193849 scopus 로고    scopus 로고
    • Liposomal curcumin with and without oxaliplatin: Effects on cell growth, apoptosis, and angiogenesis in colorectal cancer
    • L. Li, B. Ahmed, K. Mehta, and R. Kurzrock Liposomal curcumin with and without oxaliplatin: effects on cell growth, apoptosis, and angiogenesis in colorectal cancer Mol. Cancer Ther. 6 2007 1276 1282
    • (2007) Mol. Cancer Ther. , vol.6 , pp. 1276-1282
    • Li, L.1    Ahmed, B.2    Mehta, K.3    Kurzrock, R.4
  • 20
    • 70249136561 scopus 로고    scopus 로고
    • Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model
    • A.B. Kunnumakkara, P. Diagaradjane, P. Anand, K.B. Harikumar, and et al. Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model Int. J. Cancer 125 2009 2187 2197
    • (2009) Int. J. Cancer , vol.125 , pp. 2187-2197
    • Kunnumakkara, A.B.1    Diagaradjane, P.2    Anand, P.3    Harikumar, K.B.4
  • 21
    • 84900036041 scopus 로고    scopus 로고
    • Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA
    • C. Kantara, M. O'Connell, S. Sarkar, S. Moya, and et al. Curcumin promotes autophagic survival of a subset of colon cancer stem cells, which are ablated by DCLK1-siRNA Cancer Res. 74 2014 2487 2498
    • (2014) Cancer Res. , vol.74 , pp. 2487-2498
    • Kantara, C.1    O'Connell, M.2    Sarkar, S.3    Moya, S.4
  • 22
    • 73349094986 scopus 로고    scopus 로고
    • Curcumin and cancer cells: How many ways can curry kill tumor cells selectively?
    • J. Ravindran, S. Prasad, and B.B. Aggarwal Curcumin and cancer cells: how many ways can curry kill tumor cells selectively? AAPS J. 11 2009 495 510
    • (2009) AAPS J. , vol.11 , pp. 495-510
    • Ravindran, J.1    Prasad, S.2    Aggarwal, B.B.3
  • 23
    • 84929253711 scopus 로고    scopus 로고
    • Novel anti-angiogenic effects of aromatic-turmerone, essential oil isolated from spice turmeric
    • G.G.L. Yue, H.F. Kwok, J.K.M. Lee, L. Jiang, and et al. Novel anti-angiogenic effects of aromatic-turmerone, essential oil isolated from spice turmeric J. Funct. Foods 15 2015 243 253
    • (2015) J. Funct. Foods , vol.15 , pp. 243-253
    • Yue, G.G.L.1    Kwok, H.F.2    Lee, J.K.M.3    Jiang, L.4
  • 25
    • 84859741795 scopus 로고    scopus 로고
    • Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice
    • L. Zhongfa, M. Chiu, J. Wang, W. Chen, and et al. Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice Cancer Chemothe.r Pharmacol. 69 2012 679 689
    • (2012) Cancer Chemothe.r Pharmacol. , vol.69 , pp. 679-689
    • Zhongfa, L.1    Chiu, M.2    Wang, J.3    Chen, W.4
  • 27
    • 0034721809 scopus 로고    scopus 로고
    • Occurrence of orally administered curcuminoid as glucuronide and glucuronide/sulfate conjugates in rat plasma
    • A. Asai, and T. Miyazawa Occurrence of orally administered curcuminoid as glucuronide and glucuronide/sulfate conjugates in rat plasma Life Sci. 67 2000 2785 2793
    • (2000) Life Sci. , vol.67 , pp. 2785-2793
    • Asai, A.1    Miyazawa, T.2
  • 28
    • 55749100319 scopus 로고    scopus 로고
    • Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: A Bcl-2- and superoxide dismutase 2-dependent mechanism
    • S. Priego, F. Feddi, P. Ferrer, S. Mena, and et al. Natural polyphenols facilitate elimination of HT-29 colorectal cancer xenografts by chemoradiotherapy: a Bcl-2- and superoxide dismutase 2-dependent mechanism Mol. Cancer Ther. 7 2008 3330 3342
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 3330-3342
    • Priego, S.1    Feddi, F.2    Ferrer, P.3    Mena, S.4
  • 29
    • 68349106656 scopus 로고    scopus 로고
    • Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models
    • M. Yanagisawa, K. Fujimoto-Ouchi, K. Yorozu, Y. Yamashita, and K. Mori Antitumor activity of bevacizumab in combination with capecitabine and oxaliplatin in human colorectal cancer xenograft models Oncol. Rep. 22 2009 241 247
    • (2009) Oncol. Rep. , vol.22 , pp. 241-247
    • Yanagisawa, M.1    Fujimoto-Ouchi, K.2    Yorozu, K.3    Yamashita, Y.4    Mori, K.5
  • 30
    • 84856963775 scopus 로고    scopus 로고
    • Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype
    • J. Jiang, Y. Zhang, S. Chuai, Z. Wang, and et al. Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype Oncogene 31 2012 671 682
    • (2012) Oncogene , vol.31 , pp. 671-682
    • Jiang, J.1    Zhang, Y.2    Chuai, S.3    Wang, Z.4
  • 31
    • 84930965767 scopus 로고    scopus 로고
    • Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite
    • G.G.L. Yue, J.K. Lee, H.F. Kwok, L. Cheng, and et al. Novel PI3K/AKT targeting anti-angiogenic activities of 4-vinylphenol, a new therapeutic potential of a well-known styrene metabolite Sci. Rep. 5 2015 11149
    • (2015) Sci. Rep. , vol.5 , pp. 11149
    • Yue, G.G.L.1    Lee, J.K.2    Kwok, H.F.3    Cheng, L.4
  • 32
    • 40949108125 scopus 로고    scopus 로고
    • Diphenyl difluoroketone: A curcumin derivative with potent in vivo anticancer activity
    • D. Subramaniam, R. May, S.M. Sureban, K.B. Lee, and et al. Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity Cancer Res. 68 2008 1962 1969
    • (2008) Cancer Res. , vol.68 , pp. 1962-1969
    • Subramaniam, D.1    May, R.2    Sureban, S.M.3    Lee, K.B.4
  • 33
    • 54949123511 scopus 로고    scopus 로고
    • Immunohistochemistry in the evaluation of neovascularization in tumor xenografts
    • D. Wang, C.R. Stockard, L. Harkins, P. Lott, and et al. Immunohistochemistry in the evaluation of neovascularization in tumor xenografts Biotechnol. Histochem. 83 2008 179 189
    • (2008) Biotechnol. Histochem. , vol.83 , pp. 179-189
    • Wang, D.1    Stockard, C.R.2    Harkins, L.3    Lott, P.4
  • 35
    • 77955048970 scopus 로고    scopus 로고
    • Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa
    • G.G.L. Yue, B.C. Chan, P.M. Hon, M.Y. Lee, and et al. Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa Food Chem. Toxicol. 48 2010 2011 2020
    • (2010) Food Chem. Toxicol. , vol.48 , pp. 2011-2020
    • Yue, G.G.L.1    Chan, B.C.2    Hon, P.M.3    Lee, M.Y.4
  • 36
    • 77955270560 scopus 로고    scopus 로고
    • Immunostimulatory activities of polysaccharide extract isolated from Curcuma longa
    • G.G.L. Yue, B.C. Chan, P.M. Hon, E.J. Kennelly, and et al. Immunostimulatory activities of polysaccharide extract isolated from Curcuma longa Int. J. Biol. Macromol. 47 2010 342 347
    • (2010) Int. J. Biol. Macromol. , vol.47 , pp. 342-347
    • Yue, G.G.L.1    Chan, B.C.2    Hon, P.M.3    Kennelly, E.J.4
  • 37
    • 0032926620 scopus 로고    scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in mice
    • M.H. Pan, T.M. Huang, and J.K. Lin Biotransformation of curcumin through reduction and glucuronidation in mice Drug Metab. Dispos. 27 1999 486 494
    • (1999) Drug Metab. Dispos. , vol.27 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 38
    • 84861632327 scopus 로고    scopus 로고
    • Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions
    • H. Yu, and Q. Huang Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions J. Agric. Food. Chem. 60 2012 5373 5379
    • (2012) J. Agric. Food. Chem. , vol.60 , pp. 5373-5379
    • Yu, H.1    Huang, Q.2
  • 39
    • 84855221053 scopus 로고    scopus 로고
    • Effect on pro-inflammatory and antioxidant genes and bioavailable distribution of whole turmeric vs curcumin: Similar root but different effects
    • R.C. Martin, H.S. Aiyer, D. Malik, and Y. Li Effect on pro-inflammatory and antioxidant genes and bioavailable distribution of whole turmeric vs curcumin: similar root but different effects Food Chem. Toxicol. 50 2012 227 231
    • (2012) Food Chem. Toxicol. , vol.50 , pp. 227-231
    • Martin, R.C.1    Aiyer, H.S.2    Malik, D.3    Li, Y.4
  • 40
    • 84911458443 scopus 로고    scopus 로고
    • Synergistic effects of curcumin and bevacizumab on cell signaling pathways in hepatocellular carcinoma
    • J.Z. Gao, J.L. Du, Y.L. Wang, J. Li, and et al. Synergistic effects of curcumin and bevacizumab on cell signaling pathways in hepatocellular carcinoma Oncol. Lett. 9 2015 295 299
    • (2015) Oncol. Lett. , vol.9 , pp. 295-299
    • Gao, J.Z.1    Du, J.L.2    Wang, Y.L.3    Li, J.4
  • 41
    • 84901085326 scopus 로고    scopus 로고
    • Furanodiene, a natural small molecule suppresses metastatic breast cancer cell migration and invasion in vitro
    • Z. Zhong, W. Tan, X. Chen, and Y. Wang Furanodiene, a natural small molecule suppresses metastatic breast cancer cell migration and invasion in vitro Eur. J. Pharmacol. 737 2014 1 10
    • (2014) Eur. J. Pharmacol. , vol.737 , pp. 1-10
    • Zhong, Z.1    Tan, W.2    Chen, X.3    Wang, Y.4
  • 42
    • 84947423040 scopus 로고    scopus 로고
    • Identification of a novel compound (beta-sesquiphellandrene) from turmeric (Curcuma longa) with anticancer potential: Comparison with curcumin
    • A.K. Tyagi, S. Prasad, W. Yuan, S. Li, and B.B. Aggarwal Identification of a novel compound (beta-sesquiphellandrene) from turmeric (Curcuma longa) with anticancer potential: comparison with curcumin Invest. New Drugs 33 2015 1175 1186
    • (2015) Invest. New Drugs , vol.33 , pp. 1175-1186
    • Tyagi, A.K.1    Prasad, S.2    Yuan, W.3    Li, S.4    Aggarwal, B.B.5
  • 43
    • 84930084889 scopus 로고    scopus 로고
    • Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy
    • M.I. James, C. Iwuji, G. Irving, A. Karmokar, and et al. Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy Cancer Lett. 364 2015 135 141
    • (2015) Cancer Lett. , vol.364 , pp. 135-141
    • James, M.I.1    Iwuji, C.2    Irving, G.3    Karmokar, A.4


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