메뉴 건너뛰기




Volumn 9, Issue 1, 2015, Pages 295-299

Synergistic effects of curcumin and bevacizumab on cell signaling pathways in hepatocellular carcinoma

Author keywords

Curcumin; Hepatocellular carcinoma; K ras; Signaling pathway; Vascular endothelial growth factor; Vascular endothelial growth factor blocker

Indexed keywords

BEVACIZUMAB; CURCUMIN; DIETHYLNITROSAMINE; K RAS PROTEIN; MESSENGER RNA; VASCULOTROPIN RECEPTOR;

EID: 84911458443     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2014.2694     Document Type: Article
Times cited : (25)

References (35)
  • 2
    • 77952671109 scopus 로고    scopus 로고
    • Receptor cross-talk in angiogenesis: Mapping environmental cues to cell phenotype using a stochastic, Boolean signaling network model
    • Bauer AL, Jackson TL, Jiang Y and Rohlf T: Receptor cross-talk in angiogenesis: mapping environmental cues to cell phenotype using a stochastic, Boolean signaling network model. J Theor Biol 264: 838-846, 2010.
    • (2010) J Theor Biol , vol.264 , pp. 838-846
    • Bauer, A.L.1    Jackson, T.L.2    Jiang, Y.3    Rohlf, T.4
  • 4
    • 84866436255 scopus 로고    scopus 로고
    • Lentivirus-mediated siRNA targeting VEGF inhibits gastric cancer growth in vivo
    • Sun P, Yu H, Zhang WQ, Hu M and Lv R: Lentivirus-mediated siRNA targeting VEGF inhibits gastric cancer growth in vivo.Oncol Rep 28: 1687-1692, 2012.
    • (2012) Oncol Rep , vol.28 , pp. 1687-1692
    • Sun, P.1    Yu, H.2    Zhang, W.Q.3    Hu, M.4    Lv, R.5
  • 5
    • 84874375402 scopus 로고    scopus 로고
    • Prognostic significance of serum level of vascular endothelial growth factor receptor-2 in hepatocellular carcinoma patients after transcatheter arterial chemoembolization
    • In Chinese
    • Meng QW, Li Y, Hu BS, Shao PJ, Zhan MX, Yu XY and Lu LG: Prognostic significance of serum level of vascular endothelial growth factor receptor-2 in hepatocellular carcinoma patients after transcatheter arterial chemoembolization. Zhonghua Yi Xue Za Zhi 93: 341-4, 2013 (In Chinese).
    • (2013) Zhonghua Yi Xue Za Zhi , vol.93 , pp. 341-344
    • Meng, Q.W.1    Li, Y.2    Hu, B.S.3    Shao, P.J.4    Zhan, M.X.5    Yu, X.Y.6    Lu, L.G.7
  • 6
    • 78650175085 scopus 로고    scopus 로고
    • Reexpression of ARHI inhibits tumor growth and angiogenesis and impairs the mTOR/VEGF pathway in hepatocellular carcinoma
    • Zhao X, Li J, Zhuo J and Cai L: Reexpression of ARHI inhibits tumor growth and angiogenesis and impairs the mTOR/VEGF pathway in hepatocellular carcinoma. Biochem Biophys Res Commun 403: 417-421, 2010.
    • (2010) Biochem Biophys Res Commun , vol.403 , pp. 417-421
    • Zhao, X.1    Li, J.2    Zhuo, J.3    Cai, L.4
  • 7
    • 84881002286 scopus 로고    scopus 로고
    • MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42
    • Wang R, Zhao N, Li S, Fang JH, Chen MX, Yang J, Jia WH, Yuan Y and Zhuang SM: MicroRNA-195 suppresses angiogenesis and metastasis of hepatocellular carcinoma by inhibiting the expression of VEGF, VAV2, and CDC42. Hepatology 58: 642-653, 2013.
    • (2013) Hepatology , vol.58 , pp. 642-653
    • Wang, R.1    Zhao, N.2    Li, S.3    Fang, J.H.4    Chen, M.X.5    Yang, J.6    Jia, W.H.7    Yuan, Y.8    Zhuang, S.M.9
  • 10
    • 33846325144 scopus 로고    scopus 로고
    • Mda-7 in combination with bevacizumab treatment produces a synergistic and complete inhibitory affect on lung tumor xenograft
    • Inoue S, Hartman A, Branch CD, Bucana CD, Bekele BN, Stephens LC, Chada S and Ramesh R: mda-7 in combination with bevacizumab treatment produces a synergistic and complete inhibitory affect on lung tumor xenograft. Mol Ther 15: 287-294, 2007.
    • (2007) Mol Ther , vol.15 , pp. 287-294
    • Inoue, S.1    Hartman, A.2    Branch, C.D.3    Bucana, C.D.4    Bekele, B.N.5    Stephens, L.C.6    Chada, S.7    Ramesh, R.8
  • 14
    • 84902127811 scopus 로고    scopus 로고
    • Wogonin inhibits LPS-induced tumor angiogenesis via suppressing PI3K/Akt/NF-κB signaling
    • Zhao K, Song X, Huang Y, Yao J, Zhou M, Li Z, You Q, Guo Q, and Lu N: Wogonin inhibits LPS-induced tumor angiogenesis via suppressing PI3K/Akt/NF-κB signaling. Eur J Pharmacol 737: 57-69, 2014.
    • (2014) Eur J Pharmacol , vol.737 , pp. 57-69
    • Zhao, K.1    Song, X.2    Huang, Y.3    Yao, J.4    Zhou, M.5    Li, Z.6    You, Q.7    Guo, Q.8    Lu, N.9
  • 16
    • 77955282027 scopus 로고    scopus 로고
    • Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase
    • Lee J, Choi KJ, Lim MJ, Hong F, Choi TG, Tak E, Lee S, Kim YJ, Chang SG, Cho JM, et al: Proto-oncogenic H-Ras, K-Ras, and N-Ras are involved in muscle differentiation via phosphatidylinositol 3-kinase. Cell Res 20: 919-934, 2010.
    • (2010) Cell Res , vol.20 , pp. 919-934
    • Lee, J.1    Choi, K.J.2    Lim, M.J.3    Hong, F.4    Choi, T.G.5    Tak, E.6    Lee, S.7    Kim, Y.J.8    Chang, S.G.9    Cho, J.M.10
  • 17
    • 84911444269 scopus 로고    scopus 로고
    • Genetic systems to investigate regulation of oncogenes and tumour suppressor genes in Drosophila
    • Lee JE, Cranna NJ, Chahal AS and Quinn LM: Genetic systems to investigate regulation of oncogenes and tumour suppressor genes in Drosophila. Cells 1: 1182-1196, 2012.
    • (2012) Cells , vol.1 , pp. 1182-1196
    • Lee, J.E.1    Cranna, N.J.2    Chahal, A.S.3    Quinn, L.M.4
  • 19
    • 1242317802 scopus 로고    scopus 로고
    • Oncogenes and tumor angiogenesis: The question of vascular “supply” and vascular “demand”
    • Rak J and Yu JL: Oncogenes and tumor angiogenesis: the question of vascular “supply” and vascular “demand”. Semin Cancer Biol 14: 93-104, 2004.
    • (2004) Semin Cancer Biol , vol.14 , pp. 93-104
    • Rak, J.1    Yu, J.L.2
  • 22
    • 68949091981 scopus 로고    scopus 로고
    • Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis
    • Yang JC, Teng CF, Wu HC, Tsai HW, Chuang HC, Tsai TF, Hsu YH, Huang W, Wu LW and Su IJ: Enhanced expression of vascular endothelial growth factor-A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis.Hepatology 49: 1962-1971, 2009.
    • (2009) Hepatology , vol.49 , pp. 1962-1971
    • Yang, J.C.1    Teng, C.F.2    Wu, H.C.3    Tsai, H.W.4    Chuang, H.C.5    Tsai, T.F.6    Hsu, Y.H.7    Huang, W.8    Wu, L.W.9    Su, I.J.10
  • 23
    • 58149376548 scopus 로고    scopus 로고
    • Molecular mechanisms of hepatocellular carcinoma
    • Aravalli RN, Steer CJ and Cressman EN: Molecular mechanisms of hepatocellular carcinoma. Hepatology 48: 2047-2063, 2008.
    • (2008) Hepatology , vol.48 , pp. 2047-2063
    • Aravalli, R.N.1    Steer, C.J.2    Cressman, E.N.3
  • 25
    • 79955026310 scopus 로고    scopus 로고
    • Death pathways triggered by activated Ras in cancer cells
    • Overmeyer JH and Maltese WA: Death pathways triggered by activated Ras in cancer cells. Front Biosci (Landmark Ed) 16: 1693-1713, 2011.
    • (2011) Front Biosci (Landmark Ed) , vol.16 , pp. 1693-1713
    • Overmeyer, J.H.1    Maltese, W.A.2
  • 29
    • 84882944107 scopus 로고    scopus 로고
    • A new method for identifying stem-like cells in esophageal cancer cell lines
    • Almanaa TN, Geusz ME and Jamasbi RJ: A new method for identifying stem-like cells in esophageal cancer cell lines. J Cancer 4: 536-548, 2013.
    • (2013) J Cancer , vol.4 , pp. 536-548
    • Almanaa, T.N.1    Geusz, M.E.2    Jamasbi, R.J.3
  • 30
    • 34547948369 scopus 로고    scopus 로고
    • Curcumin for chemoprevention of colon cancer
    • Johnson JJ and Mukhtar H: Curcumin for chemoprevention of colon cancer. Cancer Lett 255: 170-181, 2007.
    • (2007) Cancer Lett , vol.255 , pp. 170-181
    • Johnson, J.J.1    Mukhtar, H.2
  • 31
    • 84889769276 scopus 로고    scopus 로고
    • Curcumin suppresses doxorubicin-induced epithelial-mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells
    • Chen WC, Lai YA, Lin YC, Ma JW, Huang LF, Yang NS, Ho CT, Kuo SC and Way TD: Curcumin suppresses doxorubicin-induced epithelial-mesenchymal transition via the inhibition of TGF-β and PI3K/AKT signaling pathways in triple-negative breast cancer cells. J Agric Food Chem 61: 11817-11824, 2013.
    • (2013) J Agric Food Chem , vol.61 , pp. 11817-11824
    • Chen, W.C.1    Lai, Y.A.2    Lin, Y.C.3    Ma, J.W.4    Huang, L.F.5    Yang, N.S.6    Ho, C.T.7    Kuo, S.C.8    Way, T.D.9
  • 32
    • 78651299419 scopus 로고    scopus 로고
    • Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma
    • Sun ZJ, Chen G, Zhang W, Hu X, Liu Y, Zhou Q, Zhu LX and Zhao YF: Curcumin dually inhibits both mammalian target of rapamycin and nuclear factor-κB pathways through a crossed phosphatidylinositol 3-kinase/Akt/IκB kinase complex signaling axis in adenoid cystic carcinoma. Mol Pharmacol 79: 106-118, 2011.
    • (2011) Mol Pharmacol , vol.79 , pp. 106-118
    • Sun, Z.J.1    Chen, G.2    Zhang, W.3    Hu, X.4    Liu, Y.5    Zhou, Q.6    Zhu, L.X.7    Zhao, Y.F.8
  • 34
    • 78649726904 scopus 로고    scopus 로고
    • Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca(2+) concentration
    • Wang M, Ruan Y, Chen Q, Li S, Wang Q and Cai J: Curcumin induced HepG2 cell apoptosis-associated mitochondrial membrane potential and intracellular free Ca(2+) concentration. Eur J Pharmacol 650: 41-47, 2011.
    • (2011) Eur J Pharmacol , vol.650 , pp. 41-47
    • Wang, M.1    Ruan, Y.2    Chen, Q.3    Li, S.4    Wang, Q.5    Cai, J.6
  • 35
    • 84884994929 scopus 로고    scopus 로고
    • Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: Inhibition of tumor growth and angiogenesis
    • Ranjan AP, Mukerjee A, Helson L, Gupta R and Vishwanatha JK: Efficacy of liposomal curcumin in a human pancreatic tumor xenograft model: inhibition of tumor growth and angiogenesis.Anticancer Res 33: 3603-3609, 2013.
    • (2013) Anticancer Res , vol.33 , pp. 3603-3609
    • Ranjan, A.P.1    Mukerjee, A.2    Helson, L.3    Gupta, R.4    Vishwanatha, J.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.