The anti-inflammatory protein TSG-6 regulates chemokine function by inhibiting chemokine/glycosaminoglycan interactions

Journal of Biological Chemistry

Volumn 291, Issue 24, 2016, Pages 12627-12640

  Dyer, Douglas P ^a,b   Salanga, Catherina L ^a   Johns, Scott C ^c,d   Valdambrini, Elena ^e,f   Fuster, Mark M ^c,d   Milner, Caroline M ^e,f   Day, Anthony J ^e,f   Handel, Tracy M ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF MANCHESTER   (United Kingdom)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; BINS; CELL MEMBRANES; CELLS; CYTOLOGY; ENDOTHELIAL CELLS; PROTEINS; VIRUSES;

ANTI-INFLAMMATORIES; ANTI-INFLAMMATORY EFFECTS; ANTI-INFLAMMATORY PROTEINS; BROAD SPECIFICITIES; MULTIFUNCTIONAL PROTEIN; NEUTROPHIL INFILTRATION; NEUTROPHIL MIGRATION; PRO-INFLAMMATORY STIMULI;

PEPTIDES;

CHEMOKINE; CUTANEOUS T CELL ATTRACTING CHEMOKINE; CXCL4 CHEMOKINE; GAG PROTEIN; GLYCOSAMINOGLYCAN; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; MONOCYTE CHEMOTACTIC PROTEIN 3; RANTES; REGULATOR PROTEIN; SECONDARY LYMPHOID TISSUE CHEMOKINE; STROMAL CELL DERIVED FACTOR 1; TSG 6 PROTEIN; UNCLASSIFIED DRUG; CELL ADHESION MOLECULE; HEPARIN; PROTEIN BINDING; TNFAIP6 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATIONAL STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ANIMAL; CELL ADHESION; CELL CULTURE; CELL LINE; CELL MOTION; CYTOLOGY; ENDOTHELIUM CELL; GENETICS; HUMAN; METABOLISM; MOLECULAR MODEL; MUTATION; SURFACE PLASMON RESONANCE;

ANIMALS; BINDING SITES; CELL ADHESION; CELL ADHESION MOLECULES; CELL LINE; CELL MOVEMENT; CELLS, CULTURED; CHEMOKINES; ENDOTHELIAL CELLS; GLYCOSAMINOGLYCANS; HEPARIN; HUMANS; MODELS, MOLECULAR; MUTATION; PROTEIN BINDING; SURFACE PLASMON RESONANCE;

EID: 84974530371     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.720953     Document Type: Article

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