Towards personalized diagnostics via longitudinal study of the human plasma N-glycome

Biochimica et Biophysica Acta - General Subjects

Volumn 1860, Issue 8, 2016, Pages 1728-1738

  Hennig, René ^a,b   Cajic, Samanta ^a   Borowiak, Matthias ^b   Hoffmann, Marcus ^a   Kottler, Robert ^a   Reichl, Udo ^a,c   Rapp, Erdmann ^a,b  

^a MAX PLANCK INSTITUTE FOR DYNAMICS OF COMPLEX TECHNICAL SYSTEMS   (Germany)

^b GlyXera GmbH   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

Author keywords

Glycomics; Long term stability; Longitudinal study; N glycosylation; Personalized diagnostics; xCGE LIF

Indexed keywords

CARBOHYDRATE; N GLYCOME; UNCLASSIFIED DRUG; POLYSACCHARIDE;

ADULT; ALCOHOL CONSUMPTION; ALLERGY; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; COHORT ANALYSIS; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FLUORESCENCE; FOOD INTAKE; GEL ELECTROPHORESIS; HUMAN; LASER INDUCED FLUORESCENCE DETECTION; LIFESTYLE; LONGITUDINAL STUDY; MALE; MEASUREMENT PRECISION; PERSONALIZED DIAGNOSTICS; PERSONALIZED MEDICINE; PRIORITY JOURNAL; SEASONAL VARIATION; SLEEP; BLOOD; FOLLOW UP; GLYCOBIOLOGY; PROCEDURES;

ADULT; FOLLOW-UP STUDIES; GLYCOMICS; HUMANS; MALE; POLYSACCHARIDES; PRECISION MEDICINE;

EID: 84973889500     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2016.03.035     Document Type: Article

References (65)

1. K. Landsteiner Ueber Agglutinationserscheinungen normalen menschlichen Blutes Wien. Klin. Wochenschr. 14 1901 1132 1134
2. W.M. Watkins The ABO blood group system: historical background Transfus. Med. 11 2001 243 265
3. W. Laroy, R. Contreras, and N. Callewaert Glycome mapping on DNA sequencing equipment Nat. Protoc. 1 2006 397 405
4. L. Royle, M.P. Campbell, C.M. Radcliffe, D.M. White, D.J. Harvey, J.L. Abrahams, Y. Kim, G.W. Henry, N.A. Shadick, M.E. Weinblatt, D.M. Lee, P.M. Rudd, and R.A. Dwek HPLC-based analysis of serum N-glycans on a 96-well plate platform with dedicated database software Anal. Biochem. 376 2008 1 12
5. J. Schwarzer, E. Rapp, and U. Reichl N-glycan analysis by CGE-LIF: profiling influenza A virus hemagglutinin N-glycosylation during vaccine production Electrophoresis 29 2008 4203 4214
6. L.R. Ruhaak, R. Hennig, C. Huhn, M. Borowiak, R.J.E.M. Dolhain, A.M. Deelder, E. Rapp, and M. Wuhrer Optimized workflow for preparation of APTS-labeled N-glycans allowing high-throughput analysis of human plasma glycomes using 48-channel multiplexed CGE-LIF J. Proteome Res. 9 2010 6655 6664
7. D. Vanderschaeghe, A. Szekrenyes, C. Wenz, M. Gassmann, N. Naik, M. Bynum, H. Yin, J. Delanghe, A. Guttman, and N. Callewaert High-throughput profiling of the serum N-glycome on capillary electrophoresis microfluidics systems: toward clinical Implementation of GlycoHepatoTest Anal. Chem. 82 2010 7408 7415
8. R.S. Tirumalai, K.C. Chan, D.A. Prieto, H.J. Issaq, T.P. Conrads, and T.D. Veenstra Characterization of the low molecular weight human serum proteome Mol. Cell. Proteomics 2 2003 1096 1103
9. D.F. Zielinska, F. Gnad, J.R. Wisniewski, and M. Mann Precision mapping of an in vivo N-glycoproteome reveals rigid topological and sequence constraints Cell 141 2010 897 907
10. J.E. Huffman, M. Pučić-Baković, L. Klarić, R. Hennig, M.H.J. Selman, F. Vučković, M. Novokmet, J. Krištić, M. Borowiak, T. Muth, O. Polašek, G. Razdorov, O. Gornik, R. Plomp, E. Theodoratou, A.F. Wright, I. Rudan, C. Hayward, H. Campbell, A.M. Deelder, U. Reichl, Y.S. Aulchenko, E. Rapp, M. Wuhrer, and G. Lauc Comparative performance of four methods for high-throughput glycosylation analysis of immunoglobulin G in genetic and epidemiological research Mol. Cell. Proteomics 13 2014 1598 1610
11. M. Hoffmann, K. Marx, U. Reichl, M. Wuhrer, and E. Rapp Site-specific O-glycosylation analysis of human blood plasma proteins Mol. Cell. Proteomics 2015
12. D. Kolarich, B. Lepenies, and P.H. Seeberger Glycomics, glycoproteomics and the immune system Curr. Opin. Chem. Biol. 16 2012 214 220
13. T. Liu, W.J. Qian, M.A. Gritsenko, D.G. Camp 2nd, M.E. Monroe, R.J. Moore, and R.D. Smith Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry J. Proteome Res. 4 2005 2070 2080
14. M. Wuhrer, M.I. Catalina, A.M. Deelder, and C.H. Hokke Glycoproteomics based on tandem mass spectrometry of glycopeptides J. Chromatogr. B 849 2007 115 128
15. L.R. Ruhaak, G. Zauner, C. Huhn, C. Bruggink, A.M. Deelder, and M. Wuhrer Glycan labeling strategies and their use in identification and quantification Anal. Bioanal. Chem. 397 2010 3457 3481
16. F. Clerc, K.R. Reiding, B.C. Jansen, G.S. Kammeijer, A. Bondt, and M. Wuhrer Human plasma protein N-glycosylation Glycoconj. J. 2015
17. G. Zauner, C.A.M. Koeleman, A.M. Deelder, and M. Wuhrer Mass spectrometric O-glycan analysis after combined O-glycan release by beta-elimination and 1-phenyl-3-methyl-5-pyrazolone labeling Biochim. Biophys. Acta 1820 2012 1420 1428
18. U. Lewandrowski, J. Moebius, U. Walter, and A. Sickmann Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach Mol. Cell. Proteomics 5 2006 226 233
19. K.R. Reiding, D. Blank, D.M. Kuijper, A.M. Deelder, and M. Wuhrer High-throughput profiling of protein N-glycosylation by MALDI-TOF-MS employing linkage-specific sialic acid esterification Anal. Chem. 86 2014 5784 5793
20. H. Stockmann, R.M. Duke, S. Millan Martin, and P.M. Rudd Ultrahigh throughput, ultrafiltration-based n-glycomics platform for ultraperformance liquid chromatography (ULTRA(3)) Anal. Chem. 87 2015 8316 8322
21. R. Testa, V. Vanhooren, A.R. Bonfigli, M. Boemi, F. Olivieri, A. Ceriello, S. Genovese, L. Spazzafumo, V. Borelli, M.G. Bacalini, S. Salvioli, P. Garagnani, S. Dewaele, C. Libert, and C. Franceschi N-glycomic changes in serum proteins in type 2 diabetes Mellitus correlate with complications and with metabolic syndrome parameters PLoS One 10 2015 e0119983
22. S. Albrecht, L. Unwin, M. Muniyappa, and P.M. Rudd Glycosylation as a marker for inflammatory arthritis Cancer Biomark. 14 2014 17 28
23. X.E. Liu, L. Desmyter, C.F. Gao, W. Laroy, S. Dewaele, V. Vanhooren, L. Wang, H. Zhuang, N. Callewaert, C. Libert, R. Contreras, and C. Chen N-glycomic changes in hepatocellular carcinoma patients with liver cirrhosis induced by hepatitis B virus Hepatology 46 2007 1426 1435
24. K. Noda, E. Miyoshi, N. Uozumi, S. Yanagidani, Y. Ikeda, C. Gao, K. Suzuki, H. Yoshihara, K. Yoshikawa, K. Kawano, N. Hayashi, M. Hori, and N. Taniguchi Gene expression of alpha1-6 fucosyltransferase in human hepatoma tissues: a possible implication for increased fucosylation of alpha-fetoprotein Hepatology 28 1998 944 952
25. Y. Sato, K. Nakata, Y. Kato, M. Shima, N. Ishii, T. Koji, K. Taketa, Y. Endo, and S. Nagataki Early recognition of hepatocellular carcinoma based on altered profiles of alpha-fetoprotein N. Engl. J. Med. 328 1993 1802 1806
26. D. Vanderschaeghe, W. Laroy, E. Sablon, P. Halfon, A. Van Hecke, J. Delanghe, and N. Callewaert GlycoFibroTest: DNA sequencer-based serum protein glycomics yields a highly performant liver fibrosis biomarker Mol. Cell. Proteomics 8 2009 986 994
27. U.M. Abd Hamid, L. Royle, R. Saldova, C.M. Radcliffe, D.J. Harvey, S.J. Storr, M. Pardo, R. Antrobus, C.J. Chapman, N. Zitzmann, J.F. Robertson, R.A. Dwek, and P.M. Rudd A strategy to reveal potential glycan markers from serum glycoproteins associated with breast cancer progression Glycobiology 18 2008 1105 1118
28. Z. Kyselova, Y. Mechref, P. Kang, J.A. Goetz, L.E. Dobrolecki, G.W. Sledge, L. Schnaper, R.J. Hickey, L.H. Malkas, and M.V. Novotny Breast cancer diagnosis and prognosis through quantitative measurements of serum glycan profiles Clin. Chem. 54 2008 1166 1175
29. L. Harris, H. Fritsche, R. Mennel, L. Norton, P. Ravdin, S. Taube, M.R. Somerfield, D.F. Hayes, and R.C. Bast Jr. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. 25 2007 5287 5312
30. M. Nakano, T. Nakagawa, T. Ito, T. Kitada, T. Hijioka, A. Kasahara, M. Tajiri, Y. Wada, N. Taniguchi, and E. Miyoshi Site-specific analysis of N-glycans on haptoglobin in sera of patients with pancreatic cancer: a novel approach for the development of tumor markers Int. J. Cancer 122 2008 2301 2309
31. N. Okuyama, Y. Ide, M. Nakano, T. Nakagawa, K. Yamanaka, K. Moriwaki, K. Murata, H. Ohigashi, S. Yokoyama, H. Eguchi, O. Ishikawa, T. Ito, M. Kato, A. Kasahara, S. Kawano, J. Gu, N. Taniguchi, and E. Miyoshi Fucosylated haptoglobin is a novel marker for pancreatic cancer: a detailed analysis of the oligosaccharide structure and a possible mechanism for fucosylation Int. J. Cancer 118 2006 2803 2808
32. R. Saldova, L. Royle, C.M. Radcliffe, U.M. Abd Hamid, R. Evans, J.N. Arnold, R.E. Banks, R. Hutson, D.J. Harvey, R. Antrobus, S.M. Petrescu, R.A. Dwek, and P.M. Rudd Ovarian cancer is associated with changes in glycosylation in both acute-phase proteins and IgG Glycobiology 17 2007 1344 1356
33. R. Saldova, Y. Fan, J.M. Fitzpatrick, R.W. Watson, and P.M. Rudd Core fucosylation and alpha2-3 sialylation in serum N-glycome is significantly increased in prostate cancer comparing to benign prostate hyperplasia Glycobiology 21 2011 195 205
34. J. Bones, J.C. Byrne, N. O'Donoghue, C. McManus, C. Scaife, H. Boissin, A. Nastase, and P.M. Rudd Glycomic and glycoproteomic analysis of serum from patients with stomach cancer reveals potential markers arising from host defense response mechanisms J. Proteome Res. 10 2011 1246 1265
35. L.R. Ruhaak, D.A. Barkauskas, J. Torres, C.L. Cooke, L.D. Wu, C. Stroble, S. Ozcan, C.C. Williams, M. Camorlinga, D.M. Rocke, C.B. Lebrilla, and J.V. Solnick The serum immunoglobulin G glycosylation signature of gastric cancer EuPA Open Proteomics 6 2015 1 9
36. J.N. Arnold, R. Saldova, M.C. Galligan, T.B. Murphy, Y. Mimura-Kimura, J.E. Telford, A.K. Godwin, and P.M. Rudd Novel glycan biomarkers for the detection of lung cancer J. Proteome Res. 10 2011 1755 1764
37. R. Parekh, I. Roitt, D. Isenberg, R. Dwek, and T. Rademacher Age-related galactosylation of the N-linked oligosaccharides of human serum IgG J. Exp. Med. 167 1988 1731 1736
38. K. Shikata, T. Yasuda, F. Takeuchi, T. Konishi, M. Nakata, and T. Mizuochi Structural changes in the oligosaccharide moiety of human IgG with aging Glycoconj. J. 15 1998 683 689
39. E. Yamada, Y. Tsukamoto, R. Sasaki, K. Yagyu, and N. Takahashi Structural changes of immunoglobulin G oligosaccharides with age in healthy human serum Glycoconj. J. 14 1997 401 405
40. A. Bondt, M.H. Selman, A.M. Deelder, J.M. Hazes, S.P. Willemsen, M. Wuhrer, and R.J. Dolhain Association between galactosylation of immunoglobulin G and improvement of rheumatoid arthritis during pregnancy is independent of sialylation J. Proteome Res. 12 2013 4522 4531
41. L.R. Ruhaak, H.W. Uh, A.M. Deelder, R.E. Dolhain, and M. Wuhrer Total plasma N-glycome changes during pregnancy J. Proteome Res. 13 2014 1657 1668
42. B. Adamczyk, T. Tharmalingam, and P.M. Rudd Glycans as cancer biomarkers Biochim. Biophys. Acta 1820 2012 1347 1353
43. A. Almeida, D. Kolarich, The promise of protein glycosylation for personalised medicine, Biochimica et Biophysica Acta (BBA) - General Subjects.
44. L.R. Ruhaak, S. Miyamoto, and C.B. Lebrilla Developments in the identification of glycan biomarkers for the detection of cancer Mol. Cell. Proteomics 12 2013 846 855
45. A. Knezevic, O. Polasek, O. Gornik, I. Rudan, H. Campbell, C. Hayward, A. Wright, I. Kolcic, N. O'Donoghue, J. Bones, P.M. Rudd, and G. Lauc Variability, heritability and environmental determinants of human plasma N-glycome J. Proteome Res. 8 2009 694 701
46. V. Borelli, V. Vanhooren, E. Lonardi, K.R. Reiding, M. Capri, C. Libert, P. Garagnani, S. Salvioli, C. Franceschi, and M. Wuhrer Plasma N-glycome signature of down syndrome J. Proteome Res. 14 2015 4232 4245
47. V. Vanhooren, L. Desmyter, X.E. Liu, M. Cardelli, C. Franceschi, A. Federico, C. Libert, W. Laroy, S. Dewaele, R. Contreras, and C. Chen N-glycomic changes in serum proteins during human aging Rejuvenation Res. 10 2007 521 531a
48. O. Gornik, J. Wagner, M. Pucic, A. Knezevic, I. Redzic, and G. Lauc Stability of N-glycan profiles in human plasma Glycobiology 19 2009 1547 1553
49. D. Reusch, M. Haberger, T. Kailich, A.K. Heidenreich, M. Kampe, P. Bulau, and M. Wuhrer High-throughput glycosylation analysis of therapeutic immunoglobulin G by capillary gel electrophoresis using a DNA analyzer mAbs 6 2014 185 196
50. C.T. Thiesler, S. Cajic, D. Hoffmann, C. Thiel, L. van Diepen, R. Hennig, M. Sgodda, R. Weissmann, U. Reichl, D. Steinemann, U. Diekmann, N.M. Huber, A. Oberbeck, T. Cantz, A.W. Kuss, C. Korner, A. Schambach, E. Rapp, and F.F. Buettner Glycomic characterization of induced pluripotent stem cells derived from a patient suffering from phosphomannomutase 2 congenital disorder of glycosylation Mol. Cell. Proteomics 2016
51. D. Vanderschaeghe, E. Debruyne, H. Vlierberghe, N. Callewaert, and J. Delanghe Analysis of c-globulin mobility on routine clinical CE equipment: Exploring its molecular basis and potential clinical utility Electrophoresis 30 2009 2617 2623
52. V. Vanhooren, S. Dewaele, C. Libert, S. Engelborghs, P.P. De Deyn, O. Toussaint, F. Debacq-Chainiaux, M. Poulain, Y. Glupczynski, C. Franceschi, K. Jaspers, I. van der Pluijm, J. Hoeijmakers, and C.C. Chen Serum N-glycan profile shift during human ageing Exp. Gerontol. 45 2010 738 743
53. F. Dall'Olio, V. Vanhooren, C.C. Chen, P.E. Slagboom, M. Wuhrer, and C. Franceschi N-glycomic biomarkers of biological aging and longevity: a link with inflammaging Ageing Res. Rev. 12 2013 685 698
54. R. Hennig, E. Rapp, R. Kottler, S. Cajic, M. Borowiak, and U. Reichl N-glycosylation fingerprinting of viral glycoproteins by xCGE-LIF Methods Mol. Biol. 1331 2015 123 143
55. T.W. McDade, S. Williams, and J.J. Snodgrass What a drop can do: dried blood spots as a minimally invasive method for integrating biomarkers into population-based research Demography 44 2007 899 925
56. R. Hennig, U. Reichl, and E. Rapp A software tool for automated high-throughput processing of CGE-LIF based glycoanalysis data, generated by a multiplexing capillary DNA sequencer Glycoconj. J. 28 2011 331
57. R. Kottler, M. Mank, R. Hennig, B. Muller-Werner, B. Stahl, U. Reichl, and E. Rapp Development of a high-throughput glycoanalysis method for the characterization of oligosaccharides in human milk utilizing multiplexed capillary gel electrophoresis with laser-induced fluorescence detection Electrophoresis 34 2013 2323 2336
58. A. Varki, R.D. Cummings, J.D. Esko, H.H. Freeze, P. Stanley, J.D. Marth, C.R. Bertozzi, G.W. Hart, and M.E. Etzler Symbol nomenclature for glycan representation Proteomics 9 2009 5398 5399
59. D. Reusch, M. Haberger, M.H. Selman, P. Bulau, A.M. Deelder, M. Wuhrer, and N. Engler High-throughput work flow for IgG Fc-glycosylation analysis of biotechnological samples Anal. Biochem. 432 2013 82 89
60. M.H. Selman, M. Hoffmann, G. Zauner, L.A. McDonnell, C.I. Balog, E. Rapp, A.M. Deelder, and M. Wuhrer MALDI-TOF-MS analysis of sialylated glycans and glycopeptides using 4-chloro-alpha-cyanocinnamic acid matrix Proteomics 12 2012 1337 1348
61. M.H. Selman, R.J. Derks, A. Bondt, M. Palmblad, B. Schoenmaker, C.A. Koeleman, F.E. van de Geijn, R.J. Dolhain, A.M. Deelder, and M. Wuhrer Fc specific IgG glycosylation profiling by robust nano-reverse phase HPLC-MS using a sheath-flow ESI sprayer interface J. Proteome 75 2012 1318 1329
62. M. Piagnerelli, K.Z. Boudjeltia, V. Nuyens, D. De Backer, F. Su, Z. Wang, J.L. Vincent, and M. Vanhaeverbeek Rapid alterations in transferrin sialylation during sepsis Shock 24 2005 48 52
63. O. Gornik, and G. Lauc Glycosylation of serum proteins in inflammatory diseases Dis. Markers 25 2008 267 278
64. C.M. Karsten, M.K. Pandey, J. Figge, R. Kilchenstein, P.R. Taylor, M. Rosas, J.U. McDonald, S.J. Orr, M. Berger, D. Petzold, V. Blanchard, A. Winkler, C. Hess, D.M. Reid, I.V. Majoul, R.T. Strait, N.L. Harris, G. Kohl, E. Wex, R. Ludwig, D. Zillikens, F. Nimmerjahn, F.D. Finkelman, G.D. Brown, M. Ehlers, and J. Kohl Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcgammaRIIB and dectin-1 Nat. Med. 18 2012 1401 1406
65. R. Carrell, and J. Travis α1-Antitrypsin and the serpins: variation and countervariation Trends Biochem. Sci. 10 1985 20 24