메뉴 건너뛰기




Volumn 35, Issue 23, 2016, Pages 2991-3003

SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 7; MICRORNA; MICRORNA 200; OCCLUDIN; SPROUTY 2; SPROUTY PROTEIN; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR ZEB1; UNCLASSIFIED DRUG; ETS1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MIRN150 MICRORNA, HUMAN; MIRN200 MICRORNA, HUMAN; SIGNAL PEPTIDE; SPRY2 PROTEIN, HUMAN; ZEB1 PROTEIN, HUMAN;

EID: 84973863209     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2015.366     Document Type: Article
Times cited : (43)

References (61)
  • 1
    • 41049103244 scopus 로고    scopus 로고
    • Sprouty proteins, masterminds of receptor tyrosine kinase signaling
    • Cabrita MA, Christofori G. Sprouty proteins, masterminds of receptor tyrosine kinase signaling. Angiogenesis 2008; 11: 53-62.
    • (2008) Angiogenesis , vol.11 , pp. 53-62
    • Cabrita, M.A.1    Christofori, G.2
  • 3
    • 0037197922 scopus 로고    scopus 로고
    • The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins
    • Egan JE, Hall AB, Yatsula BA, Bar-Sagi D. The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins. Proc Natl Acad Sci USA 2002; 99: 6041-6046.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 6041-6046
    • Egan, J.E.1    Hall, A.B.2    Yatsula, B.A.3    Bar-Sagi, D.4
  • 4
    • 0242684548 scopus 로고    scopus 로고
    • Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops
    • Rubin C, Litvak V, Medvedovsky H, Zwang Y, Lev S, Yarden Y. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops. Curr Biol 2003; 13: 297-307.
    • (2003) Curr Biol , vol.13 , pp. 297-307
    • Rubin, C.1    Litvak, V.2    Medvedovsky, H.3    Zwang, Y.4    Lev, S.5    Yarden, Y.6
  • 5
    • 0037119950 scopus 로고    scopus 로고
    • Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling
    • Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY et al. Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling. EMBO J 2002; 21: 4796-4808.
    • (2002) EMBO J , vol.21 , pp. 4796-4808
    • Wong, E.S.1    Fong, C.W.2    Lim, J.3    Yusoff, P.4    Low, B.C.5    Langdon, W.Y.6
  • 6
    • 23744489852 scopus 로고    scopus 로고
    • Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation
    • Haglund K, Schmidt MH, Wong ES, Guy GR, Dikic I. Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation. EMBO Rep 2005; 6: 635-641.
    • (2005) EMBO Rep , vol.6 , pp. 635-641
    • Haglund, K.1    Schmidt, M.H.2    Wong, E.S.3    Guy, G.R.4    Dikic, I.5
  • 7
    • 77956174563 scopus 로고    scopus 로고
    • SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity
    • Barbachano A, Ordonez-Moran P, Garcia JM, Sanchez A, Pereira F, Larriba MJ et al. SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity. Oncogene 2010; 29: 4800-4813.
    • (2010) Oncogene , vol.29 , pp. 4800-4813
    • Barbachano, A.1    Ordonez-Moran, P.2    Garcia, J.M.3    Sanchez, A.4    Pereira, F.5    Larriba, M.J.6
  • 8
    • 77957110390 scopus 로고    scopus 로고
    • Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: SPROUTY/ c-Met upregulation in human colonic adenocarcinomas
    • Holgren C, Dougherty U, Edwin F, Cerasi D, Taylor I, Fichera A et al. Sprouty-2 controls c-Met expression and metastatic potential of colon cancer cells: SPROUTY/ c-Met upregulation in human colonic adenocarcinomas. Oncogene 2010; 29: 5241-5253.
    • (2010) Oncogene , vol.29 , pp. 5241-5253
    • Holgren, C.1    Dougherty, U.2    Edwin, F.3    Cerasi, D.4    Taylor, I.5    Fichera, A.6
  • 9
    • 80051899599 scopus 로고    scopus 로고
    • Differential gene expression signatures between colorectal cancers with and without KRAS mutations: Crosstalk between the KRAS pathway and other signalling pathways
    • Watanabe T, Kobunai T, Yamamoto Y, Matsuda K, Ishihara S, Nozawa K et al. Differential gene expression signatures between colorectal cancers with and without KRAS mutations: crosstalk between the KRAS pathway and other signalling pathways. Eur J Cancer 2011; 47: 1946-1954.
    • (2011) Eur J Cancer , vol.47 , pp. 1946-1954
    • Watanabe, T.1    Kobunai, T.2    Yamamoto, Y.3    Matsuda, K.4    Ishihara, S.5    Nozawa, K.6
  • 10
    • 4143139997 scopus 로고    scopus 로고
    • SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant
    • Tsavachidou D, Coleman ML, Athanasiadis G, Li S, Licht JD, Olson MF et al. SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. Cancer Res 2004; 64: 5556-5559.
    • (2004) Cancer Res , vol.64 , pp. 5556-5559
    • Tsavachidou, D.1    Coleman, M.L.2    Athanasiadis, G.3    Li, S.4    Licht, J.D.5    Olson, M.F.6
  • 14
    • 78751498848 scopus 로고    scopus 로고
    • Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: Correlation with the clinical stage of the disease
    • Feng YH, Wu CL, Tsao CJ, Chang JG, Lu PJ, Yeh KT et al. Deregulated expression of sprouty2 and microRNA-21 in human colon cancer: correlation with the clinical stage of the disease. Cancer Biol Ther 2011; 11: 111-121.
    • (2011) Cancer Biol Ther , vol.11 , pp. 111-121
    • Feng, Y.H.1    Wu, C.L.2    Tsao, C.J.3    Chang, J.G.4    Lu, P.J.5    Yeh, K.T.6
  • 15
    • 16444370423 scopus 로고    scopus 로고
    • Epigenetic inactivation of the human sprouty2 (hSPRY2) homologue in prostate cancer
    • McKie AB, Douglas DA, Olijslagers S, Graham J, Omar MM, Heer R et al. Epigenetic inactivation of the human sprouty2 (hSPRY2) homologue in prostate cancer. Oncogene 2005; 24: 2166-2174.
    • (2005) Oncogene , vol.24 , pp. 2166-2174
    • McKie, A.B.1    Douglas, D.A.2    Olijslagers, S.3    Graham, J.4    Omar, M.M.5    Heer, R.6
  • 16
    • 33644521213 scopus 로고    scopus 로고
    • Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma
    • Fong CW, Chua MS, McKie AB, Ling SH, Mason V, Li R et al. Sprouty 2, an inhibitor of mitogen-activated protein kinase signaling, is down-regulated in hepatocellular carcinoma. Cancer Res 2006; 66: 2048-2058.
    • (2006) Cancer Res , vol.66 , pp. 2048-2058
    • Fong, C.W.1    Chua, M.S.2    McKie, A.B.3    Ling, S.H.4    Mason, V.5    Li, R.6
  • 17
    • 50049125314 scopus 로고    scopus 로고
    • Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas
    • Sánchez A, Setien F, Martínez N, Oliva JL, Herranz M, Fraga MF et al. Epigenetic inactivation of the ERK inhibitor Spry2 in B-cell diffuse lymphomas. Oncogene 2008; 27: 4969-4972.
    • (2008) Oncogene , vol.27 , pp. 4969-4972
    • Sánchez, A.1    Setien, F.2    Martínez, N.3    Oliva, J.L.4    Herranz, M.5    Fraga, M.F.6
  • 18
    • 63849272814 scopus 로고    scopus 로고
    • Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas
    • Frank MJ, Dawson DW, Bensinger SJ, Hong JS, Knosp WM, Xu L et al. Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas. Blood 2009; 113: 2478-2487.
    • (2009) Blood , vol.113 , pp. 2478-2487
    • Frank, M.J.1    Dawson, D.W.2    Bensinger, S.J.3    Hong, J.S.4    Knosp, W.M.5    Xu, L.6
  • 19
    • 80052332155 scopus 로고    scopus 로고
    • Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy
    • Faratian D, Sims AH, Mullen P, Kay C, Um I, Langdon SP et al. Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy. PLoS One 2011; 6: e23772.
    • (2011) PLoS One , vol.6
    • Faratian, D.1    Sims, A.H.2    Mullen, P.3    Kay, C.4    Um, I.5    Langdon, S.P.6
  • 20
    • 77749239665 scopus 로고    scopus 로고
    • Membraneanchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine
    • Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K et al. Membraneanchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine. Proc Natl Acad Sci USA 2010; 107: 4200-4205.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 4200-4205
    • Buzza, M.S.1    Netzel-Arnett, S.2    Shea-Donohue, T.3    Zhao, A.4    Lin, C.Y.5    List, K.6
  • 22
    • 12344278405 scopus 로고    scopus 로고
    • FRS2-dependent SRC. Activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity
    • Li X, Brunton VG, Burgar HR, Wheldon LM, Heath JK, FRS2-dependent SRC. activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity. J Cell Sci 2004; 117: 6007-6017.
    • (2004) J Cell Sci , vol.117 , pp. 6007-6017
    • Li, X.1    Brunton, V.G.2    Burgar, H.R.3    Wheldon, L.M.4    Heath, J.K.5
  • 23
    • 33644521566 scopus 로고    scopus 로고
    • Regulation of Sprouty stability by Mnk1-dependent phosphorylation
    • DaSilva J, Xu L, Kim HJ, Miller WT, Bar-Sagi D. Regulation of Sprouty stability by Mnk1-dependent phosphorylation. Mol Cell Biol 2006; 26: 1898-1907.
    • (2006) Mol Cell Biol , vol.26 , pp. 1898-1907
    • DaSilva, J.1    Xu, L.2    Kim, H.J.3    Miller, W.T.4    Bar-Sagi, D.5
  • 24
    • 73649092394 scopus 로고    scopus 로고
    • HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2
    • Edwin F, Anderson K, Patel TB. HECT domain-containing E3 ubiquitin ligase Nedd4 interacts with and ubiquitinates Sprouty2. J Biol Chem 2010; 285: 255-264.
    • (2010) J Biol Chem , vol.285 , pp. 255-264
    • Edwin, F.1    Anderson, K.2    Patel, T.B.3
  • 25
    • 22144499164 scopus 로고    scopus 로고
    • Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer
    • Dhawan P, Singh AB, Deane NG, No Y, Shiou S-R, Schmidt C et al. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J Clin Invest 2005; 115: 1765-1776.
    • (2005) J Clin Invest , vol.115 , pp. 1765-1776
    • Dhawan, P.1    Singh, A.B.2    Deane, N.G.3    No, Y.4    Shiou, S.-R.5    Schmidt, C.6
  • 26
    • 44449135987 scopus 로고    scopus 로고
    • Cell polarity and cancer - Cell and tissue polarity as a non-canonical tumor suppressor
    • Lee M, Vasioukhin V. Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor. J Cell Sci 2008; 121: 1141-1150.
    • (2008) J Cell Sci , vol.121 , pp. 1141-1150
    • Lee, M.1    Vasioukhin, V.2
  • 27
    • 39049160267 scopus 로고    scopus 로고
    • The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
    • Spaderna S, Schmalhofer O, Wahlbuhl M, Dimmler A, Bauer K, Sultan A et al. The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer. Cancer Res 2008; 68: 537-544.
    • (2008) Cancer Res , vol.68 , pp. 537-544
    • Spaderna, S.1    Schmalhofer, O.2    Wahlbuhl, M.3    Dimmler, A.4    Bauer, K.5    Sultan, A.6
  • 28
    • 73549091040 scopus 로고    scopus 로고
    • Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway
    • List K, Kosa P, Szabo R, Bey AL, Wang CB, Molinolo A et al. Epithelial integrity is maintained by a matriptase-dependent proteolytic pathway. Am J Pathol 2009; 175: 1453-1463.
    • (2009) Am J Pathol , vol.175 , pp. 1453-1463
    • List, K.1    Kosa, P.2    Szabo, R.3    Bey, A.L.4    Wang, C.B.5    Molinolo, A.6
  • 30
    • 84867142054 scopus 로고    scopus 로고
    • EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins
    • Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H et al. EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol 2012; 371: 136-145.
    • (2012) Dev Biol , vol.371 , pp. 136-145
    • Lei, Z.1    Maeda, T.2    Tamura, A.3    Nakamura, T.4    Yamazaki, Y.5    Shiratori, H.6
  • 31
    • 84876914835 scopus 로고    scopus 로고
    • Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions
    • Wu CJ, Mannan P, Lu M, Udey MC. Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions. J Biol Chem 2013; 288: 12253-12268.
    • (2013) J Biol Chem , vol.288 , pp. 12253-12268
    • Wu, C.J.1    Mannan, P.2    Lu, M.3    Udey, M.C.4
  • 32
    • 79952227361 scopus 로고    scopus 로고
    • CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
    • Brown RL, Reinke LM, Damerow MS, Perez D, Chodosh LA, Yang J et al. CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression. J Clin Invest 2011; 121: 1064-1074.
    • (2011) J Clin Invest , vol.121 , pp. 1064-1074
    • Brown, R.L.1    Reinke, L.M.2    Damerow, M.S.3    Perez, D.4    Chodosh, L.A.5    Yang, J.6
  • 33
    • 84866320228 scopus 로고    scopus 로고
    • Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT)
    • Warzecha CC, Carstens RP. Complex changes in alternative pre-mRNA splicing play a central role in the epithelial-to-mesenchymal transition (EMT). Semin Cancer Biol 2012; 22: 417-427.
    • (2012) Semin Cancer Biol , vol.22 , pp. 417-427
    • Warzecha, C.C.1    Carstens, R.P.2
  • 35
    • 84863203049 scopus 로고    scopus 로고
    • TGF-beta drives epithelial-mesenchymal transition through deltaEF1-mediated downregulation of ESRP
    • Horiguchi K, Sakamoto K, Koinuma D, Semba K, Inoue A, Inoue S et al. TGF-beta drives epithelial-mesenchymal transition through deltaEF1-mediated downregulation of ESRP. Oncogene 2012; 31: 3190-3201.
    • (2012) Oncogene , vol.31 , pp. 3190-3201
    • Horiguchi, K.1    Sakamoto, K.2    Koinuma, D.3    Semba, K.4    Inoue, A.5    Inoue, S.6
  • 36
    • 35548974844 scopus 로고    scopus 로고
    • The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
    • Aigner K, Dampier B, Descovich L, Mikula M, Sultan A, Schreiber M et al. The transcription factor ZEB1 (deltaEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity. Oncogene 2007; 26: 6979-6988.
    • (2007) Oncogene , vol.26 , pp. 6979-6988
    • Aigner, K.1    Dampier, B.2    Descovich, L.3    Mikula, M.4    Sultan, A.5    Schreiber, M.6
  • 37
    • 43049103824 scopus 로고    scopus 로고
    • The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
    • Gregory PA, Bert AG, Paterson EL, Barry SC, Tsykin A, Farshid G et al. The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol 2008; 10: 593-601.
    • (2008) Nat Cell Biol , vol.10 , pp. 593-601
    • Gregory, P.A.1    Bert, A.G.2    Paterson, E.L.3    Barry, S.C.4    Tsykin, A.5    Farshid, G.6
  • 38
    • 47249091921 scopus 로고    scopus 로고
    • The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G, Kang Y. The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 2008; 283: 14910-14914.
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 39
    • 44649163918 scopus 로고    scopus 로고
    • A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
    • Burk U, Schubert J, Wellner U, Schmalhofer O, Vincan E, Spaderna S et al. A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells. EMBO Rep 2008; 9: 582-589.
    • (2008) EMBO Rep , vol.9 , pp. 582-589
    • Burk, U.1    Schubert, J.2    Wellner, U.3    Schmalhofer, O.4    Vincan, E.5    Spaderna, S.6
  • 40
    • 54049084380 scopus 로고    scopus 로고
    • A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
    • Bracken CP, Gregory PA, Kolesnikoff N, Bert AG, Wang J, Shannon MF et al. A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res 2008; 68: 7846-7854.
    • (2008) Cancer Res , vol.68 , pp. 7846-7854
    • Bracken, C.P.1    Gregory, P.A.2    Kolesnikoff, N.3    Bert, A.G.4    Wang, J.5    Shannon, M.F.6
  • 41
    • 30644457873 scopus 로고    scopus 로고
    • Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms
    • Ozaki K, Miyazaki S, Tanimura S, Kohno M. Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms. J Cell Sci 2005; 118: 5861-5871.
    • (2005) J Cell Sci , vol.118 , pp. 5861-5871
    • Ozaki, K.1    Miyazaki, S.2    Tanimura, S.3    Kohno, M.4
  • 42
    • 79953325707 scopus 로고    scopus 로고
    • Functional cooperation between Snail1 and twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition
    • Dave N, Guaita-Esteruelas S, Gutarra S, Frias A, Beltran M, Peiro S et al. Functional cooperation between Snail1 and twist in the regulation of ZEB1 expression during epithelial to mesenchymal transition. J Biol Chem 2011; 286: 12024-12032.
    • (2011) J Biol Chem , vol.286 , pp. 12024-12032
    • Dave, N.1    Guaita-Esteruelas, S.2    Gutarra, S.3    Frias, A.4    Beltran, M.5    Peiro, S.6
  • 43
    • 84655169623 scopus 로고    scopus 로고
    • Epithelial cell polarity, stem cells and cancer
    • Martin-Belmonte F, Perez-Moreno M. Epithelial cell polarity, stem cells and cancer. Nat Rev Cancer 2012; 12: 23-38.
    • (2012) Nat Rev Cancer , vol.12 , pp. 23-38
    • Martin-Belmonte, F.1    Perez-Moreno, M.2
  • 45
    • 49249105861 scopus 로고    scopus 로고
    • Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells
    • Darido C, Buchert M, Pannequin J, Bastide P, Zalzali H, Mantamadiotis T et al. Defective claudin-7 regulation by Tcf-4 and Sox-9 disrupts the polarity and increases the tumorigenicity of colorectal cancer cells. Cancer Res 2008; 68: 4258-4268.
    • (2008) Cancer Res , vol.68 , pp. 4258-4268
    • Darido, C.1    Buchert, M.2    Pannequin, J.3    Bastide, P.4    Zalzali, H.5    Mantamadiotis, T.6
  • 46
    • 48749120277 scopus 로고    scopus 로고
    • Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma
    • Nakayama F, Semba S, Usami Y, Chiba H, Sawada N, Yokozaki H. Hypermethylation-modulated downregulation of claudin-7 expression promotes the progression of colorectal carcinoma. Pathobiology 2008; 75: 177-185.
    • (2008) Pathobiology , vol.75 , pp. 177-185
    • Nakayama, F.1    Semba, S.2    Usami, Y.3    Chiba, H.4    Sawada, N.5    Yokozaki, H.6
  • 47
    • 79151478291 scopus 로고    scopus 로고
    • Zeb1 and twist are more commonly expressed in metastatic than primary lung tumours and show inverse associations with claudins
    • Merikallio H, Kaarteenaho R, Paakko P, Lehtonen S, Hirvikoski P, Makitaro R et al. Zeb1 and twist are more commonly expressed in metastatic than primary lung tumours and show inverse associations with claudins. J Clin Pathol 2011; 64: 136-140.
    • (2011) J Clin Pathol , vol.64 , pp. 136-140
    • Merikallio, H.1    Kaarteenaho, R.2    Paakko, P.3    Lehtonen, S.4    Hirvikoski, P.5    Makitaro, R.6
  • 48
    • 67649211582 scopus 로고    scopus 로고
    • Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulation
    • Swat A, Dolado I, Rojas JM, Nebreda AR. Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38alpha mitogen-activated protein kinase via Sprouty2 downregulation. Mol Cell Biol 2009; 29: 3332-3343.
    • (2009) Mol Cell Biol , vol.29 , pp. 3332-3343
    • Swat, A.1    Dolado, I.2    Rojas, J.M.3    Nebreda, A.R.4
  • 49
    • 84870055922 scopus 로고    scopus 로고
    • SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation
    • Ono H, Imoto I, Kozaki K, Tsuda H, Matsui T, Kurasawa Y et al. SIX1 promotes epithelial-mesenchymal transition in colorectal cancer through ZEB1 activation. Oncogene 2012; 31: 4923-4934.
    • (2012) Oncogene , vol.31 , pp. 4923-4934
    • Ono, H.1    Imoto, I.2    Kozaki, K.3    Tsuda, H.4    Matsui, T.5    Kurasawa, Y.6
  • 50
    • 24344474155 scopus 로고    scopus 로고
    • Sprouty-2 overexpression in C2C12 cells confers myogenic differentiation properties in the presence of FGF2
    • de Alvaro C, Martinez N, Rojas JM, Lorenzo M. Sprouty-2 overexpression in C2C12 cells confers myogenic differentiation properties in the presence of FGF2. Mol Biol Cell 2005; 16: 4454-4461.
    • (2005) Mol Biol Cell , vol.16 , pp. 4454-4461
    • De Alvaro, C.1    Martinez, N.2    Rojas, J.M.3    Lorenzo, M.4
  • 51
    • 33846003532 scopus 로고    scopus 로고
    • Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3
    • Kohno Y, Okamoto T, Ishibe T, Nagayama S, Shima Y, Nishijo K et al. Expression of claudin7 is tightly associated with epithelial structures in synovial sarcomas and regulated by an Ets family transcription factor, ELF3. J Biol Chem 2006; 281: 38941-38950.
    • (2006) J Biol Chem , vol.281 , pp. 38941-38950
    • Kohno, Y.1    Okamoto, T.2    Ishibe, T.3    Nagayama, S.4    Shima, Y.5    Nishijo, K.6
  • 52
    • 34848858270 scopus 로고    scopus 로고
    • The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells
    • Aguilera O, Pena C, Garcia JM, Larriba MJ, Ordonez-Moran P, Navarro D et al. The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells. Carcinogenesis 2007; 28: 1877-1884.
    • (2007) Carcinogenesis , vol.28 , pp. 1877-1884
    • Aguilera, O.1    Pena, C.2    Garcia, J.M.3    Larriba, M.J.4    Ordonez-Moran, P.5    Navarro, D.6
  • 53
    • 0942276845 scopus 로고    scopus 로고
    • Highly efficient lentiviralmediated human cytokine transgenesis on the NOD/Scid background
    • Punzon I, Criado LM, Serrano A, Serrano F, Bernad A. Highly efficient lentiviralmediated human cytokine transgenesis on the NOD/Scid background. Blood 2004; 103: 580-582.
    • (2004) Blood , vol.103 , pp. 580-582
    • Punzon, I.1    Criado, L.M.2    Serrano, A.3    Serrano, F.4    Bernad, A.5
  • 54
    • 21344436821 scopus 로고    scopus 로고
    • Betacatenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells
    • Silva-Vargas V, Lo Celso C, Giangreco A, Ofstad T, Prowse DM, Braun KM et al. Betacatenin and Hedgehog signal strength can specify number and location of hair follicles in adult epidermis without recruitment of bulge stem cells. Dev Cell 2005; 9: 121-131.
    • (2005) Dev Cell , vol.9 , pp. 121-131
    • Silva-Vargas, V.1    Lo Celso, C.2    Giangreco, A.3    Ofstad, T.4    Prowse, D.M.5    Braun, K.M.6
  • 57
    • 77951531009 scopus 로고    scopus 로고
    • GATExplorer: Genomic and transcriptomic explorer; Mapping expression probes to gene loci, transcripts, exons and ncRNAs
    • Risueno A, Fontanillo C, Dinger ME, De Las Rivas J. GATExplorer: genomic and transcriptomic explorer; mapping expression probes to gene loci, transcripts, exons and ncRNAs. BMC Bioinform 2010; 11: 221.
    • (2010) BMC Bioinform , vol.11 , pp. 221
    • Risueno, A.1    Fontanillo, C.2    Dinger, M.E.3    De Las Rivas, J.4
  • 58
  • 60
    • 0035829361 scopus 로고    scopus 로고
    • Controlling the false discovery rate in behavior genetics research
    • Benjamini Y, Drai D, Elmer G, Kafkafi N, Golani I. Controlling the false discovery rate in behavior genetics research. Behav Brain Res 2001; 125: 279-284.
    • (2001) Behav Brain Res , vol.125 , pp. 279-284
    • Benjamini, Y.1    Drai, D.2    Elmer, G.3    Kafkafi, N.4    Golani, I.5
  • 61
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005; 102: 15545-15550.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3    Mukherjee, S.4    Ebert, B.L.5    Gillette, M.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.