Chitosan-Stearic Acid Based Polymeric Micelles for the Effective Delivery of Tamoxifen: Cytotoxic and Pharmacokinetic Evaluation

AAPS PharmSciTech

Volumn 18, Issue 3, 2017, Pages 759-768

  Thotakura, Nagarani ^a   Dadarwal, Mukesh ^a   Kumar, Pramod ^a   Sharma, Gajanand ^b   Guru, Santosh Kumar ^c   Bhushan, Shashi ^c   Raza, Kaisar ^a   Katare, Om Prakash ^b  

^a CENTRAL UNIVERSITY OF RAJASTHAN   (India)

^b PANJAB UNIVERSITY   (India)

^c CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

bioadhesion; biodistribution; drug delivery; MCF 7 cells; MTT assay

Indexed keywords

CHITOSAN; COPOLYMER; NANOCARRIER; STEARIC ACID; TAMOXIFEN; DELAYED RELEASE FORMULATION; DRUG CARRIER; LIPID; MICELLE; POLYMER; STEARIC ACID DERIVATIVE;

ANIMAL CELL; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; BREAST CANCER CELL LINE; CONJUGATE; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY ASSAY; DRUG CLEARANCE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; ELIMINATION HALF-LIFE; ERYTHROCYTE; EX VIVO STUDY; HEMOLYSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; MICELLE; MORPHOLOGY; MTT ASSAY; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SURFACE CHARGE; SUSTAINED DRUG RELEASE; ZETA POTENTIAL; ADMINISTRATION AND DOSAGE; ADVERSE EFFECTS; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECTS; MCF-7 CELL LINE; PHARMACOKINETICS; PROCEDURES; TISSUE DISTRIBUTION; TUMOR CELL LINE; WISTAR RAT;

ANIMALS; CELL LINE, TUMOR; CHITOSAN; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; LIPIDS; MCF-7 CELLS; MICELLES; POLYMERS; RATS, WISTAR; STEARIC ACIDS; TAMOXIFEN; TISSUE DISTRIBUTION;

EID: 84973667698     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-016-0563-6     Document Type: Article

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