Does short-term high dose probiotic supplementation containing Lactobacillus casei attenuate exertional-heat stress induced endotoxaemia and cytokinaemia?

International Journal of Sport Nutrition and Exercise Metabolism

Volumn 26, Issue 3, 2016, Pages 268-275

  Gill, Samantha K ^a   Allerton, Dean M ^b   Ansley Robson, Paula ^b   Hemmings, Krystal ^c   Cox, Martin ^a   Costa, Ricardo J S ^d  

^a Institute for Clean Growth and Future Mobility   (United Kingdom)

^b Faculty of Health Science   (United Kingdom)

^c UNIVERSITY OF DERBY   (United Kingdom)

^d MONASH UNIVERSITY   (Australia)

Author keywords

Gastrointestinal; Inflammatory; Permeability

Indexed keywords

ENDOTOXIN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; PROBIOTIC AGENT; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ADULT; ARTICLE; BEVERAGE; BLOOD SAMPLING; BODY HEIGHT; BODY MASS; CALORIC INTAKE; CROSSOVER PROCEDURE; CYTOKINEMIA; DIET SUPPLEMENTATION; ENDOTOXEMIA; ENVIRONMENTAL TEMPERATURE; EXERCISE; HEAT STRESS; HUMAN; HUMAN EXPERIMENT; HYDRATION; INFLAMMATION; LACTOBACILLUS CASEI; MALE; PLASMA; PLASMA OSMOLALITY; PROTEIN BLOOD LEVEL; RUNNING; BLOOD; CONTROLLED STUDY; DRINKING; ENDURANCE; HEAT; HEAT SHOCK RESPONSE; OXYGEN CONSUMPTION; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME; YOUNG ADULT;

ADULT; CROSS-OVER STUDIES; CYTOKINES; DRINKING; ENDOTOXEMIA; ENDOTOXINS; ENERGY INTAKE; HEAT-SHOCK RESPONSE; HOT TEMPERATURE; HUMANS; LACTOBACILLUS CASEI; MALE; OXYGEN CONSUMPTION; PHYSICAL ENDURANCE; PROBIOTICS; RUNNING; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84973461694     PISSN: 1526484X     EISSN: 15432742     Source Type: Journal    
DOI: 10.1123/ijsnem.2015-0186     Document Type: Article

References (38)

1. Borg, G. A. (1982). Psychophysical bases of perceived exertion. Medicine and Science in Sports and Exercise, 14, 377-381. PubMed doi:10.1249/00005768-198205000-00012
2. Bosenberg, A. T., Brock-Utne, J. G., Gaffin, S. L., Wells, M. T., & Blake, G. T. (1988). Strenuous exercise causes systemic endotoxemia. Journal of Applied Physiology, 65, 106-108. PubMed
3. Brock-Utne, J. G., Gaffin, S. L., Wells, M. T., Gathiram, P., Sohar, E., James, M. F., Norman, R. J. (1988). Endotoxemia in exhausted runners after a long-distance race. South African Medical Journal, 73, 533-536. PubMed
4. Boyle, R. J., Robins-Browne, R. M., & Tang, M. L. K. (2006). Probiotic use in clinical practice: what are the risks? The American Journal of Clinical Nutrition, 83, 1256-1264. PubMed
5. Camus, G., Poortmans, J., Nys, M., Deby-Dupont, G., Duchateau, J., Deby, C., & Lamy, M. (1997). Mild endotoxaemia and the inflammatory response induced by a marathon race. Clinical Science, 92, 415-122. PubMed doi:10.1042/cs0920415
6. Caradonna, L., Amati, L., Magrone, T., Pellegrino, N. M., Jirillo, E., & Caccavo, D. (2000). Enteric bacteria, lipopolysaccharide and related cytokines in irritable bowel disease: Biological and clinical significance. Journal of Endotoxin Research, 6, 205-214. PubMed
7. Christensen, H. R., Larsen, C. N., Kaestel, P., Rosholm, L. B., Sternberg, C., Michaelsen, K. F., & Frøkiaer, H. (2006). Immunomodulating potential of supplementation with probiotics: a dose-response study in healthy young adults. FEMS Immunology and Medical Microbiology, 47, 380-390. PubMed doi:10.1111/j.1574-695X.2006.00109.x
8. Costa, R. J. S., Oliver, S. J., Laing, S. J., Walters, R., Bilzon, J. L., & Walsh, N. P. (2009). Influence of timing of post exercise carbohydrate-protein ingestion on selected immune indices. International Journal of Sport Nutrition and Exercise Metabolism, 19, 366-384. PubMed
9. Costa, R. J. S., Harper-Smith, A. D., Oliver, S. J., Walters, R., Maassen, N., Bilzon, J. L. J., & Walsh, N. P. (2010). The effects of two nights of sleep deprivation with and without energy restriction on selected immune responses at rest and in response to cold exposure. European Journal of Applied Physiology, 109, 417-428. PubMed doi:10.1007/s00421-010-1378-x
10. Costa, R. J. S., Richardson, K., Birch, T., Francis, A., Bilzon, J. L. J., & Walsh, N. P. (2011). Effects of immediate postexercise carbohydrate ingestion with and without protein on circulating cytokine balance. Journal of Sports Sciences, 29(Suppl. 2), S99-S100.
11. Costa, R. J. S., Swancott, A. J. M., Gill, S., Hankey, J., Scheer, V., Murray, A., & Thake, C. D. (2013). Compromised energy and macronutrient intake of ultra-endurance runners during a multi-stage ultra-marathon conducted in a hot ambient environment. International Journal of Sports Science, 3, 51-62.
12. Dill, D. B., & Costill, D. L. (1974). Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. Journal of Applied Physiology, 37, 247-248. PubMed
13. Ford, A. C., Quigley, E. M., Lacy, B. E., Lembo, A. J., Saito, Y. A., Schiller, L. R., Moayyedi, P. (2014). Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. The American Journal of Gastroenterology, 109, 1547-1561. PubMed doi:10.1038/ajg.2014.202
14. Gill, S. K., Teixeira, A., Rama, L., Rosado, F., Hankey, J., Scheer, V., Costa, R. J. S. (2015a). Circulatory endotoxin concentration and cytokine profile in response to exertional-heat stress during a multi-stage ultra-marathon competition. Exercise Immunology Review, 21, 114-128. PubMed
15. Gill, S. K., Hankey, J., Wright, A., Hemmings, K., Allterton, D. M., Ansley-Robson, P., & Costa, R. J. S. (2015b). The Impact of a 24-hour Ultra-Marathon on Circulatory Endotoxin and Cytokine Profile. International Journal of Sports Medicine, 36, 688-695. PubMed doi:10.1055/s-0034-1398535
16. Hamilton-Miller, J. M. T., Shah, S., & Smith, C. (1996). "Probiotic" remedies are not what they seem. British Medical Journal, 312, 55-56. PubMed doi:10.1136/bmj.312.7022.55c
17. Hollies, N. R. S., & Goldman, R. F. (1977). Psychological scaling in comfort assessment. In N. R. S. Hollies & R. F. Goldman (Eds.), Clothing comfort: Interaction of thermal, ventilation, construction, and assessment factors (pp. 107-120). Michigan, USA: Ann Arbor Science Publishers Inc.
18. Hörmannsperger, G., & Haller, D. (2010). Molecular crosstalk of probiotic bacteria with the intestinal immune system: clinical relevance in the context of inflammatory bowel disease. International Journal of Medical Microbiology, 300, 63-73. PubMed doi:10.1016/j.ijmm.2009.08.006
19. Jeukendrup, A. E., Vet-Joop, K., Sturk, A., Stegen, J. H. J. C., Senden, J., Saris, W. H. M., & Wagenmakers, A. J. M. (2000). Relationship between gastro-intestinal complaints and endotoxaemia, cytokine release and the acute-phase reaction during and after a long-distance triathlon in highly trained men. Clinical Science, 98, 47-55. PubMed doi:10.1042/cs0980047
20. Lambert, G. P., Lang, J., Bull, A., Pfeifer, P. C., Eckerson, J., Moore, G., O'Brien, J. (2008). Fluid restriction during running increases GI permeability. International Journal of Sports Medicine, 29, 194-198. PubMed doi:10.1055/s-2007-965163
21. Lamprecht, M., Bogner, S., Schippinger, G., Steinbauer, K., Fankhauser, F., Hallstroem, S., Greilberger, J. F. (2012). Probiotic supplementation affects markers of intestinal barrier, oxidation, and inflammation in trained men; a randomized, double-blinded, placebo-controlled trial. Journal of the International Society of Sports Nutrition, 9, 45. PubMed
22. Langlands, S. J., Hopkins, M. J., Coleman, N., & Cummings, J. H. (2004). Prebiotic carbohydrates modify the mucosa associated microflora of the human large bowel. Gut, 53, 1610-1616. PubMed doi:10.1136/gut.2003.037580
23. Larsen, C. N., Nielsen, S., Kaestel, P., Brockmann, E., Bennedsen, M., Christensen, H. R., Michaelsen, K. F. (2006). Dose-response study of probiotic bacteria Bifidobacterium animalis subsp lactis BB-12 and Lactobacillus paracasei subsp paracasei CRL-341 in healthy young adults. European Journal of Clinical Nutrition, 60, 1284-1293. PubMed doi:10.1038/sj.ejcn. 1602450
24. Lim, C. L., & Mackinnon, L. T. (2006). The roles of exerciseinduced immune system disturbances in the pathology of heat stroke. Sports Medicine (Auckland, N. Z.), 36, 39-64. PubMed doi:10.2165/00007256-200636010-00004
25. Looijer-van Langen, M. A., & Dieleman, L. A. (2009). Prebiotics in chronic intestinal inflammation. Inflammatory Bowel Diseases, 15, 454-462. PubMed doi:10.1002/ibd.20737
26. Moayyedi, P., Ford, A. C., Talley, N. J., Cremonini, F., Foxx-Orenstein, A. E., Brandt, L. J., & Quigley, E. M. M. (2010). The efficacy of probiotics in the treatment of irritable bowel syndrome: A systematic review. Gut, 59, 325-332. PubMed doi:10.1136/gut.2008.167270
27. Morris, G., Berk, M., Galecki, P., & Maes, M. (2014). The Emerging Role of Autoimmunity in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/cfs). Molecular Neurobiology, 49, 741-756. PubMed doi:10.1007/s12035-013-8553-0
28. O'Connor, F. G., Casa, D. J., Bergeron, M. F., Carter, R., Deuster, P., Heled, Y., Sawka, M. (2010). American College of Sports Medicine round table on exertional heat stroke. Return to duty/return to play: Conference Proceedings. Current Sports Medicine Reports, 9, 314-321. PubMed doi:10.1249/JSR.0b013e3181f1d183
29. Rav-Acha, M., Hadad, E., Epstein, Y., Heled, Y., & Moran, D. S. (2004). Fatal Exertional Heat Stroke: A Case Series. The American Journal of the Medical Sciences, 328, 84-87. PubMed doi:10.1097/00000441-200408000-00003
30. Rodes, L., Khan, A., Paul, A., Coussa-Charley, M., Marinescu, D., Tomaro-Duchesneau, C., Prakash, S. (2013). Effect of Probiotics Lactobacillus and Bifidobacterium on Gut-Derived Lipopolysaccharides and Inflammatory Cytokines: An In Vitro Study Using a Human Colonic Microbiota Model. Journal of Microbiology and Biotechnology, 23, 518-526. PubMed doi:10.4014/jmb.1205.05018
31. Salminen, S., Isolauri, E., & Salminen, E. (1996). Clinical uses of probiotics for stabilizing the gut mucosal barrier: successful strains and future challenges. Antonie van Leeuwenhoek, 70, 347-358. PubMed doi:10.1007/BF00395941
32. Sartor, B. R. (2004). Therapeutic manipulation of the enteric microflora in inflammatory bowel diseases: antibiotics, probiotics, and prebiotics. Gastroenterology, 126, 1620-1633. PubMed doi:10.1053/j.gastro.2004.03.024
33. Sazawal, S., Hiremath, G., Dhingra, U., Malik, P., Deb, S., & Black, R. E. (2006). Efficacy of probiotics in prevention of acute diarrhoea: a meta-analysis of masked, randomised, placebo-controlled trials. The Lancet Infectious Diseases, 6, 374-382. PubMed doi:10.1016/S1473-3099 (06) 70495-9
34. Selkirk, G. A., McLellan, T. M., Wright, H. E., & Rhind, S. G. (2008). Mild endotoxemia, NF-kB translocation, and cytokine increase during exertional heat stress in trained and untrained individuals. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 295, R611-R623. PubMed doi:10.1152/ajpregu.00917.2007
35. Shing, C. M., Peake, J. M., Lim, C. L., Briskey, D., Walsh, N. P., Fortes, M. B., Vitetta, L. (2014). Effects of probiotics supplementation on gastrointestinal permeability, inflammation and exercise performance in the heat. European Journal of Applied Physiology, 114, 93-103. PubMed doi:10.1007/s00421-013-2748-y
36. Spanhaak, S., Havenaar, R., & Schaafsma, G. (1998). The effect of consumption of milk fermented by Lactobacillus casei strain Shirota on the intestinal microflora and immune parameters in humans. European Journal of Clinical Nutrition, 52, 899-907. PubMed doi:10.1038/sj.ejcn. 1600663
37. Tillett, E., & Loosemore, M. (2009). Setting standards for the prevention and management of travellers' diarrhoea in elite athletes: an audit of one team during the Youth Commonwealth Games in India. British Journal of Sports Medicine, 43, 1045-1048. PubMed doi:10.1136/bjsm.2009.063396
38. van Wijck, K., Lenaerts, K., Grootjans, J., Wijnands, K. P., Poeze, M., van Loon, L. J., Buurman, W. A. (2012). Physiology and pathophysiology of splanchnic hypoperfusion and intestinal injury during exercise: strategies for evaluation and preventions. The American Journal of Physiology, 303, G155-G168. PubMed