-
2
-
-
77649179672
-
Eicosanoids and cancer
-
Wang, D., and Dubois, R. N. (2010) Eicosanoids and cancer. Nat. Rev. Cancer 10, 181-193
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 181-193
-
-
Wang, D.1
Dubois, R.N.2
-
3
-
-
84901921079
-
Pro-resolving lipid mediators are leads for resolution physiology
-
Serhan, C. N. (2014) Pro-resolving lipid mediators are leads for resolution physiology. Nature 510, 92-101
-
(2014)
Nature
, vol.510
, pp. 92-101
-
-
Serhan, C.N.1
-
4
-
-
0020597565
-
Leukotrienes: Mediators of immediate hypersensitivity reactions and inflammation
-
Samuelsson, B. (1983) Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation. Science 220, 568-575
-
(1983)
Science
, vol.220
, pp. 568-575
-
-
Samuelsson, B.1
-
5
-
-
0020434503
-
On the mechanism of biosynthesis of leukotrienes and related compounds
-
Panossian, A., Hamberg, M., and Samuelsson, B. (1982) On the mechanism of biosynthesis of leukotrienes and related compounds. FEBS Lett. 150, 511-513
-
(1982)
FEBS Lett.
, vol.150
, pp. 511-513
-
-
Panossian, A.1
Hamberg, M.2
Samuelsson, B.3
-
6
-
-
0038205601
-
5-Lipoxygenase activation by MAPKAPK-2 and ERKs
-
Werz, O., Bürkert, E., Fischer, L., Szellas, D., Dishart, D., Samuelsson, B., Rådmark, O., and Steinhilber, D. (2003) 5-Lipoxygenase activation by MAPKAPK-2 and ERKs. Adv. Exp. Med. Biol. 525, 129-132
-
(2003)
Adv. Exp. Med. Biol.
, vol.525
, pp. 129-132
-
-
Werz, O.1
Bürkert, E.2
Fischer, L.3
Szellas, D.4
Dishart, D.5
Samuelsson, B.6
Rådmark, O.7
Steinhilber, D.8
-
7
-
-
0034624019
-
The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity
-
Hammarberg, T., Provost, P., Persson, B., and Rådmark, O. (2000) The N-terminal domain of 5-lipoxygenase binds calcium and mediates calcium stimulation of enzyme activity. J. Biol. Chem. 275, 38787-38793
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38787-38793
-
-
Hammarberg, T.1
Provost, P.2
Persson, B.3
Rådmark, O.4
-
8
-
-
0026014460
-
Influx of extracellular calcium is required for the membrane translocation of 5-lipoxygenase and leukotriene synthesis
-
Wong, A., Cook, M. N., Foley, J. J., Sarau, H. M., Marshall, P., and Hwang, S. M. (1991) Influx of extracellular calcium is required for the membrane translocation of 5-lipoxygenase and leukotriene synthesis. Biochemistry 30, 9346-9354
-
(1991)
Biochemistry
, vol.30
, pp. 9346-9354
-
-
Wong, A.1
Cook, M.N.2
Foley, J.J.3
Sarau, H.M.4
Marshall, P.5
Hwang, S.M.6
-
9
-
-
0027093272
-
A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells
-
Kargman, S., Vickers, P. J., and Evans, J. F. (1992) A23187-induced translocation of 5-lipoxygenase in osteosarcoma cells. J. Cell Biol. 119, 1701-1709
-
(1992)
J. Cell Biol.
, vol.119
, pp. 1701-1709
-
-
Kargman, S.1
Vickers, P.J.2
Evans, J.F.3
-
10
-
-
0345008359
-
On the nature of the 5-lipoxygenasereaction in human leukocytes: Enzyme purification and requirement for multiple stimulatory factors
-
Rouzer, C. A., and Samuelsson, B. (1985) On the nature of the 5-lipoxygenasereaction in human leukocytes: enzyme purification and requirement for multiple stimulatory factors. Proc. Natl. Acad. Sci. USA 82, 6040-6044
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 6040-6044
-
-
Rouzer, C.A.1
Samuelsson, B.2
-
11
-
-
33748348405
-
Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production
-
Rakonjac, M., Fischer, L., Provost, P.,Werz, O., Steinhilber, D., Samuelsson, B., and Rådmark, O. (2006) Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production. Proc. Natl. Acad. Sci. USA 103, 13150-13155
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 13150-13155
-
-
Rakonjac, M.1
Fischer, L.2
Provost, P.3
Werz, O.4
Steinhilber, D.5
Samuelsson, B.6
Rådmark, O.7
-
12
-
-
84905643479
-
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis
-
Basavarajappa, D., Wan, M., Lukic, A., Steinhilber, D., Samuelsson, B., and Rådmark, O. (2014) Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis. Proc. Natl. Acad. Sci. USA 111, 11371-11376
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 11371-11376
-
-
Basavarajappa, D.1
Wan, M.2
Lukic, A.3
Steinhilber, D.4
Samuelsson, B.5
Rådmark, O.6
-
13
-
-
0025022489
-
Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis
-
Dixon, R. A., Diehl, R. E., Opas, E., Rands, E., Vickers, P. J., Evans, J. F., Gillard, J. W., and Miller, D. K. (1990) Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343, 282-284
-
(1990)
Nature
, vol.343
, pp. 282-284
-
-
Dixon, R.A.1
Diehl, R.E.2
Opas, E.3
Rands, E.4
Vickers, P.J.5
Evans, J.F.6
Gillard, J.W.7
Miller, D.K.8
-
14
-
-
0027323992
-
5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase
-
Abramovitz, M., Wong, E., Cox, M. E., Richardson, C. D., Li, C., and Vickers, P. J. (1993) 5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase. Eur. J. Biochem. 215, 105-111
-
(1993)
Eur. J. Biochem.
, vol.215
, pp. 105-111
-
-
Abramovitz, M.1
Wong, E.2
Cox, M.E.3
Richardson, C.D.4
Li, C.5
Vickers, P.J.6
-
15
-
-
84903726819
-
An experimental cell-based model for studying the cell biology and molecular pharmacology of 5-lipoxygenase-activating protein in leukotriene biosynthesis
-
Gerstmeier, J., Weinigel, C., Barz, D., Werz, O., and Garscha, U. (2014) An experimental cell-based model for studying the cell biology and molecular pharmacology of 5-lipoxygenase-activating protein in leukotriene biosynthesis. Biochim. Biophys. Acta 1840, 2961-2969
-
(2014)
Biochim. Biophys. Acta
, vol.1840
, pp. 2961-2969
-
-
Gerstmeier, J.1
Weinigel, C.2
Barz, D.3
Werz, O.4
Garscha, U.5
-
16
-
-
0027416398
-
5-lipoxygenase-activating protein is an arachidonate binding protein
-
Mancini, J. A., Abramovitz, M., Cox, M. E., Wong, E., Charleson, S., Perrier, H., Wang, Z., Prasit, P., and Vickers, P. J. (1993) 5-lipoxygenase-activating protein is an arachidonate binding protein. FEBS Lett. 318, 277-281
-
(1993)
FEBS Lett.
, vol.318
, pp. 277-281
-
-
Mancini, J.A.1
Abramovitz, M.2
Cox, M.E.3
Wong, E.4
Charleson, S.5
Perrier, H.6
Wang, Z.7
Prasit, P.8
Vickers, P.J.9
-
17
-
-
34547560098
-
Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein
-
Ferguson, A. D., McKeever, B. M., Xu, S., Wisniewski, D., Miller, D. K., Yamin, T. T., Spencer, R. H., Chu, L., Ujjainwalla, F., Cunningham, B. R., Evans, J. F., and Becker, J. W. (2007) Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein. Science 317, 510-512
-
(2007)
Science
, vol.317
, pp. 510-512
-
-
Ferguson, A.D.1
McKeever, B.M.2
Xu, S.3
Wisniewski, D.4
Miller, D.K.5
Yamin, T.T.6
Spencer, R.H.7
Chu, L.8
Ujjainwalla, F.9
Cunningham, B.R.10
Evans, J.F.11
Becker, J.W.12
-
18
-
-
0025098441
-
MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes
-
Rouzer, C. A., Ford-Hutchinson, A. W., Morton, H. E., and Gillard, J. W. (1990) MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes. J. Biol. Chem. 265, 1436-1442
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 1436-1442
-
-
Rouzer, C.A.1
Ford-Hutchinson, A.W.2
Morton, H.E.3
Gillard, J.W.4
-
19
-
-
62649099134
-
Distinct parts of leukotriene C(4) synthase interact with 5-lipoxygenase and 5-lipoxygenase activating protein
-
Strid, T., Svartz, J., Franck, N., Hallin, E., Ingelsson, B., Söderström, M., and Hammarström, S. (2009) Distinct parts of leukotriene C(4) synthase interact with 5-lipoxygenase and 5-lipoxygenase activating protein. Biochem. Biophys. Res. Commun. 381, 518-522
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.381
, pp. 518-522
-
-
Strid, T.1
Svartz, J.2
Franck, N.3
Hallin, E.4
Ingelsson, B.5
Söderström, M.6
Hammarström, S.7
-
20
-
-
58149511977
-
The nuclear membrane organization of leukotriene synthesis
-
Mandal, A. K., Jones, P. B., Bair, A. M., Christmas, P., Miller, D., Yamin, T. T., Wisniewski, D., Menke, J., Evans, J. F., Hyman, B. T., Bacskai, B., Chen, M., Lee, D. M., Nikolic, B., and Soberman, R. J. (2008) The nuclear membrane organization of leukotriene synthesis. Proc. Natl. Acad. Sci. USA 105, 20434-20439
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 20434-20439
-
-
Mandal, A.K.1
Jones, P.B.2
Bair, A.M.3
Christmas, P.4
Miller, D.5
Yamin, T.T.6
Wisniewski, D.7
Menke, J.8
Evans, J.F.9
Hyman, B.T.10
Bacskai, B.11
Chen, M.12
Lee, D.M.13
Nikolic, B.14
Soberman, R.J.15
-
21
-
-
58149398605
-
ERK-mediated regulation of leukotriene biosynthesis by androgens: A molecular basis for gender differences in inflammation and asthma
-
Pergola, C., Dodt, G., Rossi, A., Neunhoeffer, E., Lawrenz, B., Northoff, H., Samuelsson, B., Rådmark, O., Sautebin, L., and Werz, O. (2008) ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma. Proc. Natl. Acad. Sci. USA 105, 19881-19886
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19881-19886
-
-
Pergola, C.1
Dodt, G.2
Rossi, A.3
Neunhoeffer, E.4
Lawrenz, B.5
Northoff, H.6
Samuelsson, B.7
Rådmark, O.8
Sautebin, L.9
Werz, O.10
-
22
-
-
80053925891
-
Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes
-
Pergola, C., Rogge, A., Dodt, G., Northoff, H., Weinigel, C., Barz, D., Rådmark, O., Sautebin, L., and Werz, O. (2011) Testosterone suppresses phospholipase D, causing sex differences in leukotriene biosynthesis in human monocytes. FASEB J. 25, 3377-3387
-
(2011)
FASEB J
, vol.25
, pp. 3377-3387
-
-
Pergola, C.1
Rogge, A.2
Dodt, G.3
Northoff, H.4
Weinigel, C.5
Barz, D.6
Rådmark, O.7
Sautebin, L.8
Werz, O.9
-
23
-
-
0036464591
-
Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes
-
Werz, O., Bürkert, E., Samuelsson, B., Rådmark, O., and Steinhilber, D. (2002) Activation of 5-lipoxygenase by cell stress is calcium independent in human polymorphonuclear leukocytes. Blood 99, 1044-1052
-
(2002)
Blood
, vol.99
, pp. 1044-1052
-
-
Werz, O.1
Bürkert, E.2
Samuelsson, B.3
Rådmark, O.4
Steinhilber, D.5
-
24
-
-
33751252292
-
Direct observation of individual endogenous protein complexes in situ by proximity ligation
-
Söderberg, O., Gullberg, M., Jarvius, M., Ridderstråle, K., Leuchowius, K. J., Jarvius, J., Wester, K., Hydbring, P., Bahram, F., Larsson, L. G., and Landegren, U. (2006) Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat. Methods 3, 995-1000
-
(2006)
Nat. Methods
, vol.3
, pp. 995-1000
-
-
Söderberg, O.1
Gullberg, M.2
Jarvius, M.3
Ridderstråle, K.4
Leuchowius, K.J.5
Jarvius, J.6
Wester, K.7
Hydbring, P.8
Bahram, F.9
Larsson, L.G.10
Landegren, U.11
-
25
-
-
84901407496
-
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)
-
Pergola, C., Gerstmeier, J., Mönch, B., Çalişkan, B., Luderer, S., Weinigel, C., Barz, D., Maczewsky, J., Pace, S., Rossi, A., Sautebin, L., Banoglu, E., and Werz, O. (2014) The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP). Br. J. Pharmacol. 171, 3051-3064
-
(2014)
Br. J. Pharmacol.
, vol.171
, pp. 3051-3064
-
-
Pergola, C.1
Gerstmeier, J.2
Mönch, B.3
Çalişkan, B.4
Luderer, S.5
Weinigel, C.6
Barz, D.7
Maczewsky, J.8
Pace, S.9
Rossi, A.10
Sautebin, L.11
Banoglu, E.12
Werz, O.13
-
26
-
-
0037066761
-
Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase
-
Kulkarni, S., Das, S., Funk, C. D., Murray, D., and Cho, W. (2002) Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase. J. Biol. Chem. 277, 13167-13174
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 13167-13174
-
-
Kulkarni, S.1
Das, S.2
Funk, C.D.3
Murray, D.4
Cho, W.5
-
27
-
-
0142151057
-
5-lipoxygenase: Cellular biology and molecular pharmacology
-
Werz, O. (2002) 5-lipoxygenase: cellular biology and molecular pharmacology. Curr. Drug Targets Inflamm. Allergy 1, 23-44
-
(2002)
Curr. Drug Targets Inflamm. Allergy
, vol.1
, pp. 23-44
-
-
Werz, O.1
-
28
-
-
84869232992
-
The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer
-
Bair, A. M., Turman, M. V., Vaine, C. A., Panettieri, R. A., Jr., and Soberman, R. J. (2012) The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer. Mol. Biol. Cell 23, 4456-4464
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 4456-4464
-
-
Bair, A.M.1
Turman, M.V.2
Vaine, C.A.3
Panettieri, R.A.4
Soberman, R.J.5
-
29
-
-
49549119156
-
Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins
-
Martinez Molina, D., Eshaghi, S., and Nordlund, P. (2008) Catalysis within the lipid bilayer-structure and mechanism of the MAPEG family of integral membrane proteins. Curr. Opin. Struct. Biol. 18, 442-449
-
(2008)
Curr. Opin. Struct. Biol.
, vol.18
, pp. 442-449
-
-
Martinez Molina, D.1
Eshaghi, S.2
Nordlund, P.3
-
30
-
-
0024348059
-
L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor
-
Gillard, J., Ford-Hutchinson, A. W., Chan, C., Charleson, S., Denis, D., Foster, A., Fortin, R., Leger, S., McFarlane, C. S., Morton, H., et al. (1989) L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2 - dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor. Can. J. Physiol. Pharmacol. 67, 456-464
-
(1989)
Can. J. Physiol. Pharmacol.
, vol.67
, pp. 456-464
-
-
Gillard, J.1
Ford-Hutchinson, A.W.2
Chan, C.3
Charleson, S.4
Denis, D.5
Foster, A.6
Fortin, R.7
Leger, S.8
McFarlane, C.S.9
Morton, H.10
-
31
-
-
0025728109
-
5-lipoxygenase inhibitory activity of zileuton
-
Carter, G. W., Young, P. R., Albert, D. H., Bouska, J., Dyer, R., Bell, R. L., Summers, J. B., and Brooks, D. W. (1991) 5-lipoxygenase inhibitory activity of zileuton.J. Pharmacol. Exp. Ther. 256, 929-937
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.256
, pp. 929-937
-
-
Carter, G.W.1
Young, P.R.2
Albert, D.H.3
Bouska, J.4
Dyer, R.5
Bell, R.L.6
Summers, J.B.7
Brooks, D.W.8
-
32
-
-
0034704801
-
Pyrrolidine inhibitors of human cytosolic phospholipase A (2)
-
Seno, K., Okuno, T., Nishi, K., Murakami, Y., Watanabe, F., Matsuura, T., Wada, M., Fujii, Y., Yamada, M., Ogawa, T., Okada, T., Hashizume, H., Kii, M., Hara, S., Hagishita, S., Nakamoto, S., Yamada, K., Chikazawa, Y., Ueno, M., Teshirogi, I., Ono, T., and Ohtani, M. (2000) Pyrrolidine inhibitors of human cytosolic phospholipase A (2). J. Med. Chem. 43, 1041-1044
-
(2000)
J. Med. Chem.
, vol.43
, pp. 1041-1044
-
-
Seno, K.1
Okuno, T.2
Nishi, K.3
Murakami, Y.4
Watanabe, F.5
Matsuura, T.6
Wada, M.7
Fujii, Y.8
Yamada, M.9
Ogawa, T.10
Okada, T.11
Hashizume, H.12
Kii, M.13
Hara, S.14
Hagishita, S.15
Nakamoto, S.16
Yamada, K.17
Chikazawa, Y.18
Ueno, M.19
Teshirogi, I.20
Ono, T.21
Ohtani, M.22
more..
-
33
-
-
0026970250
-
BAY X1005, a new selective inhibitor of leukotriene synthesis: Pharmacology and pharmacokinetics
-
Müller-Peddinghaus, R., Fruchtmann, R., Ahr, H. J., Beckermann, B., Bühner, K., Fugmann, B., Junge, B., Matzke, M., Kohlsdorfer, C., Raddatz, S., et al. (1993) BAY X1005, a new selective inhibitor of leukotriene synthesis: pharmacology and pharmacokinetics. J. Lipid Mediat. 6, 245-248
-
(1993)
J. Lipid Mediat.
, vol.6
, pp. 245-248
-
-
Müller-Peddinghaus, R.1
Fruchtmann, R.2
Ahr, H.J.3
Beckermann, B.4
Bühner, K.5
Fugmann, B.6
Junge, B.7
Matzke, M.8
Kohlsdorfer, C.9
Raddatz, S.10
-
34
-
-
0034983085
-
Arachidonic acid as a bioactive molecule
-
Brash, A. R. (2001) Arachidonic acid as a bioactive molecule. J. Clin. Invest. 107, 1339-1345
-
(2001)
J. Clin. Invest.
, vol.107
, pp. 1339-1345
-
-
Brash, A.R.1
-
35
-
-
84922553449
-
5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease
-
Radmark, O., Werz, O., Steinhilber, D., and and Samuelsson, B. (2015) 5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease. Biochim. Biophys. Acta. 1851, 331-339
-
(2015)
Biochim. Biophys. Acta.
, vol.1851
, pp. 331-339
-
-
Radmark, O.1
Werz, O.2
Steinhilber, D.3
Samuelsson, B.4
-
36
-
-
0031766646
-
Mechanisms of the priming effect of lipopolysaccharides on the biosynthesis of leukotriene B4 in chemotactic peptide-stimulated human neutrophils
-
Surette, M. E., Dallaire, N., Jean, N., Picard, S., and Borgeat, P. (1998) Mechanisms of the priming effect of lipopolysaccharides on the biosynthesis of leukotriene B4 in chemotactic peptide-stimulated human neutrophils. FASEB J. 12, 1521-1531
-
(1998)
FASEB J
, vol.12
, pp. 1521-1531
-
-
Surette, M.E.1
Dallaire, N.2
Jean, N.3
Picard, S.4
Borgeat, P.5
-
37
-
-
84884534656
-
High capacity for leukotriene biosynthesis in peripheral blood during pregnancy
-
Schaible, A. M., Koeberle, A., Northoff, H., Lawrenz, B., Weinigel, C., Barz, D., Werz, O., and Pergola, C. (2013) High capacity for leukotriene biosynthesis in peripheral blood during pregnancy. Prostaglandins Leukot. Essent. Fatty Acids 89, 245-255
-
(2013)
Prostaglandins Leukot. Essent. Fatty Acids
, vol.89
, pp. 245-255
-
-
Schaible, A.M.1
Koeberle, A.2
Northoff, H.3
Lawrenz, B.4
Weinigel, C.5
Barz, D.6
Werz, O.7
Pergola, C.8
-
38
-
-
34347397335
-
5-Lipoxygenase: Regulation of expression and enzyme activity
-
Rådmark, O., Werz, O., Steinhilber, D., and Samuelsson, B. (2007) 5-Lipoxygenase: regulation of expression and enzyme activity. Trends Biochem. Sci. 32, 332-341
-
(2007)
Trends Biochem. Sci.
, vol.32
, pp. 332-341
-
-
Rådmark, O.1
Werz, O.2
Steinhilber, D.3
Samuelsson, B.4
-
39
-
-
21344469741
-
Development of 5-lipoxygenase inhibitors - Lessons from cellular enzyme regulation
-
Werz, O., and Steinhilber, D. (2005) Development of 5-lipoxygenase inhibitors - lessons from cellular enzyme regulation. Biochem. Pharmacol. 70, 327-333
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 327-333
-
-
Werz, O.1
Steinhilber, D.2
-
40
-
-
0021289320
-
Properties of leukotriene B4 20-hydroxylase from polymorphonuclear leukocytes
-
Powell, W. S. (1984) Properties of leukotriene B4 20-hydroxylase from polymorphonuclear leukocytes. J. Biol. Chem. 259, 3082-3089
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 3082-3089
-
-
Powell, W.S.1
-
41
-
-
0021150830
-
Omega-oxidation is the major pathway for the catabolism of leukotriene B4 in human polymorphonuclear leukocytes
-
Shak, S., and Goldstein, I. M. (1984) Omega-oxidation is the major pathway for the catabolism of leukotriene B4 in human polymorphonuclear leukocytes. J. Biol. Chem. 259, 10181-10187
-
(1984)
J. Biol. Chem.
, vol.259
, pp. 10181-10187
-
-
Shak, S.1
Goldstein, I.M.2
-
42
-
-
0023803150
-
Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187
-
Rouzer, C. A., and Kargman, S. (1988) Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187. J. Biol. Chem. 263, 10980-10988
-
(1988)
J. Biol. Chem.
, vol.263
, pp. 10980-10988
-
-
Rouzer, C.A.1
Kargman, S.2
-
43
-
-
0028049483
-
Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes
-
Lepley, R. A., and Fitzpatrick, F. A. (1994) Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes. J. Biol. Chem. 269, 2627-2631
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2627-2631
-
-
Lepley, R.A.1
Fitzpatrick, F.A.2
-
44
-
-
0023180568
-
Kinetic studies on the inactivation of 5-lipoxygenase by 5 (S)-hydroperoxyeicosatetraenoic acid
-
Aharony, D., Redkar-Brown, D. G., Hubbs, S. J., and Stein, R. L. (1987) Kinetic studies on the inactivation of 5-lipoxygenase by 5 (S)-hydroperoxyeicosatetraenoic acid. Prostaglandins 33, 85-100
-
(1987)
Prostaglandins
, vol.33
, pp. 85-100
-
-
Aharony, D.1
Redkar-Brown, D.G.2
Hubbs, S.J.3
Stein, R.L.4
-
45
-
-
0030051102
-
Oxidative inactivation of human 5-lipoxygenase in phosphatidylcholine vesicles
-
De Carolis, E., Denis, D., and Riendeau, D. (1996) Oxidative inactivation of human 5-lipoxygenase in phosphatidylcholine vesicles. Eur. J. Biochem. 235, 416-423
-
(1996)
Eur. J. Biochem.
, vol.235
, pp. 416-423
-
-
De Carolis, E.1
Denis, D.2
Riendeau, D.3
-
46
-
-
84940552056
-
The intracellular localisation and phosphorylation profile of the human 5-lipoxygenase Δ13 isoform differs from that of its full length counterpart
-
Allain, E. P., Boudreau, L. H., Flamand, N., and Surette, M. E. (2015) The intracellular localisation and phosphorylation profile of the human 5-lipoxygenase Δ13 isoform differs from that of its full length counterpart. PLoS One 10, e0132607
-
(2015)
PLoS One
, vol.10
-
-
Allain, E.P.1
Boudreau, L.H.2
Flamand, N.3
Surette, M.E.4
-
47
-
-
33644857422
-
Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils
-
Flamand, N., Lefebvre, J., Surette, M. E., Picard, S., and Borgeat, P. (2006) Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils. J. Biol. Chem. 281, 129-136
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 129-136
-
-
Flamand, N.1
Lefebvre, J.2
Surette, M.E.3
Picard, S.4
Borgeat, P.5
-
48
-
-
0027070829
-
Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors
-
Vickers, P. J., Adam, M., Charleson, S., Coppolino, M. G., Evans, J. F., and Mancini, J. A. (1992) Identification of amino acid residues of 5-lipoxygenase-activating protein essential for the binding of leukotriene biosynthesis inhibitors. Mol. Pharmacol. 42, 94-102
-
(1992)
Mol. Pharmacol.
, vol.42
, pp. 94-102
-
-
Vickers, P.J.1
Adam, M.2
Charleson, S.3
Coppolino, M.G.4
Evans, J.F.5
Mancini, J.A.6
|