Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 31, 2014, Pages 11371-11376

  Basavarajappa, Devaraj ^a   Wan, Min ^a   Lukic, Ana ^a   Steinhilber, Dieter ^b   Samuelsson, Bengt ^a   Rådmark, Olof ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b GOETHE UNIVERSITY   (Germany)

Author keywords

Eicosanoid; Inflammation; Oxylipin

Indexed keywords

5 HYDROXYICOSATETRAENOIC ACID; ACTIN BINDING PROTEIN; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONATE 5 LIPOXYGENASE ACTIVATING PROTEIN; ARACHIDONIC ACID; CALCIMYCIN; COACTOSIN LIKE PROTEIN; LEUKOTRIENE; LEUKOTRIENE A4; LEUKOTRIENE C4; LEUKOTRIENE C4 SYNTHASE; PHORBOL 13 ACETATE 12 MYRISTATE; UNCLASSIFIED DRUG;

ARTICLE; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL NUCLEUS; CELL NUCLEUS MEMBRANE; CELL STIMULATION; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MACROPHAGE; MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING;

EICOSANOID; INFLAMMATION; OXYLIPIN;

5-LIPOXYGENASE-ACTIVATING PROTEINS; ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; CELL LINE; CELL NUCLEUS; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; INTRACELLULAR MEMBRANES; IONOPHORES; LEUKOTRIENE C4; LEUKOTRIENES; MICROFILAMENT PROTEINS; MODELS, BIOLOGICAL; MONOCYTES; PROTEIN BINDING;

EID: 84905643479     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1410983111     Document Type: Article

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