Viral Spread to Enteric Neurons Links Genital HSV-1 Infection to Toxic Megacolon and Lethality

Cell Host and Microbe

Volumn 19, Issue 6, 2016, Pages 788-799

  Khoury Hanold, William ^a   Yordy, Brian ^a   Kong, Philip ^a   Kong, Yong ^a   Ge, William ^a   Szigeti Buck, Klara ^a   Ralevski, Alexandra ^a   Horvath, Tamas L ^a   Iwasaki, Akiko ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DESTRUCTION; CONTROLLED STUDY; DISEASE SEVERITY; DOWN REGULATION; ENTERIC VIRUS; FEMALE; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; GENITAL HERPES; HERPES SIMPLEX; HERPES SIMPLEX VIRUS 1; IMMUNOPATHOLOGY; INTESTINAL DYSMOTILITY; INTESTINE INNERVATION; LARGE INTESTINE; LETHALITY; MOUSE; MOUSE MODEL; NERVE CELL; NEUTROPHIL; NONHUMAN; PAIN RECEPTOR; PATHOGENESIS; PERISTALSIS; PRIORITY JOURNAL; SURVIVAL RATE; TOXIC MEGACOLON; UPREGULATION; URINE RETENTION; VIRUS GENE; VIRUS LOAD; VIRUS REPLICATION; ANIMAL; C57BL MOUSE; DISEASE MODEL; GANGLION; GENETICS; HUMAN ALPHAHERPESVIRUS 1; INTESTINE; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; SPINAL GANGLION; ULTRASTRUCTURE; VAGINA; VAGINA DISEASE; VIROLOGY; VIRUS GENOME;

ANIMALS; DISEASE MODELS, ANIMAL; ENTERIC NERVOUS SYSTEM; FEMALE; GANGLIA; GANGLIA, SPINAL; GENOME, VIRAL; HERPES GENITALIS; HERPESVIRUS 1, HUMAN; INTESTINES; MEGACOLON, TOXIC; MICE; MICE, INBRED C57BL; NEURONS; NEUTROPHILS; NOCICEPTORS; VAGINA; VAGINAL DISEASES; VIRUS REPLICATION;

EID: 84973441352     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.05.008     Document Type: Article

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