-
1
-
-
34250836327
-
The multifunctional nucleolus
-
Boisvert, F. M., van Koningsbruggen, S., Navascues, J. & Lamond, A. I. The multifunctional nucleolus. Nat. Rev. Mol. Cell Biol. 8, 574-585 (2007).
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 574-585
-
-
Boisvert, F.M.1
Van Koningsbruggen, S.2
Navascues, J.3
Lamond, A.I.4
-
2
-
-
84925286904
-
Noncoding RNAs in eukaryotic ribosome synthesis and function
-
Lafontaine, D. L. J. Noncoding RNAs in eukaryotic ribosome synthesis and function. Nat. Struct. Mol. Biol. 22, 11-19 (2015).
-
(2015)
Nat. Struct. Mol. Biol.
, vol.22
, pp. 11-19
-
-
Lafontaine, D.L.J.1
-
3
-
-
39749138785
-
A structural understanding of the dynamic ribosome machine
-
Steitz, T. A. A structural understanding of the dynamic ribosome machine. Nat. Rev. Mol. Cell Biol. 9, 242-253 (2008).
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 242-253
-
-
Steitz, T.A.1
-
4
-
-
84861908221
-
One core, two shells: Bacterial and eukaryotic ribosomes
-
Melnikov, S. et al. One core, two shells: bacterial and eukaryotic ribosomes. Nat. Struct. Mol. Biol. 19, 560-567 (2012).
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 560-567
-
-
Melnikov, S.1
-
5
-
-
70350654363
-
What recent ribosome structures have revealed about the mechanism of translation
-
Schmeing, T. M. & Ramakrishnan, V. What recent ribosome structures have revealed about the mechanism of translation. Nature 461, 1234-1242 (2009).
-
(2009)
Nature
, vol.461
, pp. 1234-1242
-
-
Schmeing, T.M.1
Ramakrishnan, V.2
-
6
-
-
84941549664
-
Ribosomopathies: How a common root can cause a tree of pathologies
-
Danilova, N. & Gazda, H. T. Ribosomopathies: how a common root can cause a tree of pathologies. Dis. Model Mech. 8, 1013-1026 (2015).
-
(2015)
Dis. Model Mech.
, vol.8
, pp. 1013-1026
-
-
Danilova, N.1
Gazda, H.T.2
-
7
-
-
77951431225
-
Ribosomopathies: Human disorders of ribosome dysfunction
-
Narla, A. & Ebert, B. L. Ribosomopathies: human disorders of ribosome dysfunction. Blood 115, 3196-3205 (2010).
-
(2010)
Blood
, vol.115
, pp. 3196-3205
-
-
Narla, A.1
Ebert, B.L.2
-
8
-
-
70350497397
-
Signaling to p53: Ribosomal proteins find their way
-
Zhang, Y. & Lu, H. Signaling to p53: ribosomal proteins find their way. Cancer Cell 16, 369-377 (2009).
-
(2009)
Cancer Cell
, vol.16
, pp. 369-377
-
-
Zhang, Y.1
Lu, H.2
-
9
-
-
84855266512
-
Guarding the 'translation apparatus': Defective ribosome biogenesis and the p53 signaling pathway
-
Chakraborty, A., Uechi, T. & Kenmochi, N. Guarding the 'translation apparatus': defective ribosome biogenesis and the p53 signaling pathway. Wiley Interdiscip. Rev. RNA 2, 507-522 (2011).
-
(2011)
Wiley Interdiscip. Rev. RNA
, vol.2
, pp. 507-522
-
-
Chakraborty, A.1
Uechi, T.2
Kenmochi, N.3
-
10
-
-
76649129549
-
Proteomics analysis of the nucleolus in adenovirus-infected cells
-
Lam, Y. W., Evans, V. C., Heesom, K. J., Lamond, A. I. & Matthews, D. A. Proteomics analysis of the nucleolus in adenovirus-infected cells. Mol. Cell. Proteomics 9, 117-130 (2010).
-
(2010)
Mol. Cell. Proteomics
, vol.9
, pp. 117-130
-
-
Lam, Y.W.1
Evans, V.C.2
Heesom, K.J.3
Lamond, A.I.4
Matthews, D.A.5
-
11
-
-
80054043851
-
Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation
-
Moore, H. M. et al. Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation. Mol. Cell. Proteomics 10, 009241 (2011).
-
(2011)
Mol. Cell. Proteomics
, vol.10
, pp. 009241
-
-
Moore, H.M.1
-
12
-
-
16844372528
-
Birth of a nucleolus: The evolution of nucleolar compartments
-
Thiry, M. & Lafontaine, D. L. J. Birth of a nucleolus: the evolution of nucleolar compartments. Trends Cell Biol. 15, 194-199 (2005).
-
(2005)
Trends Cell Biol.
, vol.15
, pp. 194-199
-
-
Thiry, M.1
Lafontaine, D.L.J.2
-
13
-
-
79954423238
-
Nucleolar structure across evolution: The transition between bi- and tricompartmentalized nucleoli lies within the class Reptilia
-
Lamaye, F., Galliot, S., Alibardi, L., Lafontaine, D. L. J. & Thiry, M. Nucleolar structure across evolution: the transition between bi- and tricompartmentalized nucleoli lies within the class Reptilia. J. Struct. Biol. 174, 352-359 (2011).
-
(2011)
J. Struct. Biol.
, vol.174
, pp. 352-359
-
-
Lamaye, F.1
Galliot, S.2
Alibardi, L.3
Lafontaine, D.L.J.4
Thiry, M.5
-
14
-
-
79954417213
-
The nucleolus: Structure/function relationship in RNA metabolism
-
Hernandez-Verdun, D., Roussel, P., Thiry, M., Sirri, V. & Lafontaine, D. L. J. The nucleolus: structure/function relationship in RNA metabolism. Wiley Interdiscip. Rev. RNA 1, 415-431 (2010).
-
(2010)
Wiley Interdiscip. Rev. RNA
, vol.1
, pp. 415-431
-
-
Hernandez-Verdun, D.1
Roussel, P.2
Thiry, M.3
Sirri, V.4
Lafontaine, D.L.J.5
-
15
-
-
0037128933
-
Cyclin-dependent kinases govern formation and maintenance of the nucleolus
-
Sirri, V., Hernandez-Verdun, D. & Roussel, P. Cyclin-dependent kinases govern formation and maintenance of the nucleolus. J. Cell Biol. 156, 969-981 (2002).
-
(2002)
J. Cell Biol.
, vol.156
, pp. 969-981
-
-
Sirri, V.1
Hernandez-Verdun, D.2
Roussel, P.3
-
16
-
-
4544330157
-
Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells
-
Leung, A. K. et al. Quantitative kinetic analysis of nucleolar breakdown and reassembly during mitosis in live human cells. J. Cell Biol. 166, 787-800 (2004).
-
(2004)
J. Cell Biol.
, vol.166
, pp. 787-800
-
-
Leung, A.K.1
-
17
-
-
65349143672
-
What the nucleolus says to a tumour pathologist
-
Derenzini, M., Montanaro, L. & Trere, D. What the nucleolus says to a tumour pathologist. Histopathology 54, 753-762 (2009).
-
(2009)
Histopathology
, vol.54
, pp. 753-762
-
-
Derenzini, M.1
Montanaro, L.2
Trere, D.3
-
18
-
-
84863736613
-
Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53
-
Bywater, M. J. et al. Inhibition of RNA polymerase I as a therapeutic strategy to promote cancer-specific activation of p53. Cancer Cell 22, 51-65 (2012).
-
(2012)
Cancer Cell
, vol.22
, pp. 51-65
-
-
Bywater, M.J.1
-
19
-
-
84892409069
-
A targeting modality for destruction of RNA polymerase I that possesses anticancer activity
-
Peltonen, K. et al. A targeting modality for destruction of RNA polymerase I that possesses anticancer activity. Cancer Cell 25, 77-90 (2014).
-
(2014)
Cancer Cell
, vol.25
, pp. 77-90
-
-
Peltonen, K.1
-
20
-
-
78649336111
-
The nucleolus under stress
-
Boulon, S., Westman, B. J., Hutten, S., Boisvert, F. M. & Lamond, A. I. The nucleolus under stress. Mol. Cell 40, 216-227 (2010).
-
(2010)
Mol. Cell
, vol.40
, pp. 216-227
-
-
Boulon, S.1
Westman, B.J.2
Hutten, S.3
Boisvert, F.M.4
Lamond, A.I.5
-
21
-
-
84886952042
-
The nucleolus: An emerging target for cancer therapy
-
Hein, N., Hannan, K. M., George, A. J., Sanij, E. & Hannan, R. D. The nucleolus: an emerging target for cancer therapy. Trends Mol. Med. 19, 643-654 (2013).
-
(2013)
Trends Mol. Med.
, vol.19
, pp. 643-654
-
-
Hein, N.1
Hannan, K.M.2
George, A.J.3
Sanij, E.4
Hannan, R.D.5
-
22
-
-
84930708678
-
Functions of ribosomal proteins in assembly of eukaryotic ribosomes in vivo
-
de la Cruz, J., Karbstein, K. & Woolford, Jr J. L. Functions of ribosomal proteins in assembly of eukaryotic ribosomes in vivo. Annu. Rev. Biochem. 84, 93-129 (2015).
-
(2015)
Annu. Rev. Biochem.
, vol.84
, pp. 93-129
-
-
De La-Cruz, J.1
Karbstein, K.2
Woolford, J.L.3
-
23
-
-
77956380533
-
Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits
-
O'Donohue, M. F., Choesmel, V., Faubladier, M., Fichant, G. & Gleizes, P. E. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. J. Cell Biol. 190, 853-866 (2010).
-
(2010)
J. Cell Biol.
, vol.190
, pp. 853-866
-
-
O'Donohue, M.F.1
Choesmel, V.2
Faubladier, M.3
Fichant, G.4
Gleizes, P.E.5
-
24
-
-
84897964300
-
A new system for naming ribosomal proteins
-
Ban, N. et al. A new system for naming ribosomal proteins. Curr. Opin. Struct. Biol. 24, 165-169 (2014).
-
(2014)
Curr. Opin. Struct. Biol.
, vol.24
, pp. 165-169
-
-
Ban, N.1
-
25
-
-
84892443134
-
5S ribosomal RNA is an essential component of a nascent ribosomal precursor complex that regulates the Hdm2-p53 checkpoint
-
Donati, G., Peddigari, S., Mercer, C. A. & Thomas, G. 5S ribosomal RNA is an essential component of a nascent ribosomal precursor complex that regulates the Hdm2-p53 checkpoint. Cell Rep. 4, 87-98 (2013).
-
(2013)
Cell Rep.
, vol.4
, pp. 87-98
-
-
Donati, G.1
Peddigari, S.2
Mercer, C.A.3
Thomas, G.4
-
26
-
-
84885833107
-
The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress
-
Sloan, K. E., Bohnsack, M. T. & Watkins, N. J. The 5S RNP couples p53 homeostasis to ribosome biogenesis and nucleolar stress. Cell Rep. 5, 237-247 (2013).
-
(2013)
Cell Rep.
, vol.5
, pp. 237-247
-
-
Sloan, K.E.1
Bohnsack, M.T.2
Watkins, N.J.3
-
27
-
-
84873410888
-
Characterization of the ribosome biogenesis landscape in E. Coli using quantitative mass spectrometry
-
Chen, S. S. & Williamson, J. R. Characterization of the ribosome biogenesis landscape in E. coli using quantitative mass spectrometry. J. Mol. Biol. 425, 767-779 (2013).
-
(2013)
J. Mol. Biol.
, vol.425
, pp. 767-779
-
-
Chen, S.S.1
Williamson, J.R.2
-
28
-
-
28444479853
-
An assembly landscape for the 30S ribosomal subunit
-
Talkington, M. W., Siuzdak, G. & Williamson, J. R. An assembly landscape for the 30S ribosomal subunit. Nature 438, 628-632 (2005).
-
(2005)
Nature
, vol.438
, pp. 628-632
-
-
Talkington, M.W.1
Siuzdak, G.2
Williamson, J.R.3
-
29
-
-
84937823133
-
A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. Coli
-
Sashital, D. G. et al. A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. coli. eLife 3, e04491 (2014).
-
(2014)
ELife
, vol.3
, pp. e04491
-
-
Sashital, D.G.1
-
30
-
-
84892725662
-
A hierarchical model for assembly of eukaryotic 60S ribosomal subunit domains
-
Gamalinda, M. et al. A hierarchical model for assembly of eukaryotic 60S ribosomal subunit domains. Genes Dev. 28, 198-210 (2014).
-
(2014)
Genes Dev.
, vol.28
, pp. 198-210
-
-
Gamalinda, M.1
-
31
-
-
35648956087
-
Analysis of the in vivo assembly pathway of eukaryotic 40S ribosomal proteins
-
Ferreira-Cerca, S. et al. Analysis of the in vivo assembly pathway of eukaryotic 40S ribosomal proteins. Mol. Cell 28, 446-457 (2007).
-
(2007)
Mol. Cell
, vol.28
, pp. 446-457
-
-
Ferreira-Cerca, S.1
-
32
-
-
84877310529
-
Structures of the human and Drosophila 80S ribosome
-
Anger, A. M. et al. Structures of the human and Drosophila 80S ribosome. Nature 497, 80-85 (2013).
-
(2013)
Nature
, vol.497
, pp. 80-85
-
-
Anger, A.M.1
-
33
-
-
83455179426
-
The nucleolus: When 2 became 3
-
Thiry, M., Lamaye, F. & Lafontaine, D. L. J. The nucleolus: when 2 became 3. Nucleus 2, 289-293 (2011).
-
(2011)
Nucleus
, vol.2
, pp. 289-293
-
-
Thiry, M.1
Lamaye, F.2
Lafontaine, D.L.J.3
-
34
-
-
77956399552
-
Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells
-
Schmitz, M. H. et al. Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells. Nat. Cell Biol. 12, 886-893 (2010).
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 886-893
-
-
Schmitz, M.H.1
-
35
-
-
78149391411
-
A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export
-
Wild, T. et al. A protein inventory of human ribosome biogenesis reveals an essential function of exportin 5 in 60S subunit export. PLoS Biol. 8, e1000522 (2010).
-
(2010)
PLoS Biol.
, vol.8
, pp. e1000522
-
-
Wild, T.1
-
36
-
-
84861634017
-
Mapping the cleavage sites on mammalian pre-rRNAs: Where do we stand?
-
Mullineux, S. T. & Lafontaine, D. L. J. Mapping the cleavage sites on mammalian pre-rRNAs: where do we stand? Biochimie 94, 1521-1532 (2012).
-
(2012)
Biochimie
, vol.94
, pp. 1521-1532
-
-
Mullineux, S.T.1
Lafontaine, D.L.J.2
-
37
-
-
50649096622
-
The role of human ribosomal proteins in the maturation of rRNA and ribosome production
-
Robledo, S. et al. The role of human ribosomal proteins in the maturation of rRNA and ribosome production. RNA 14, 1918-1929 (2008).
-
(2008)
RNA
, vol.14
, pp. 1918-1929
-
-
Robledo, S.1
-
38
-
-
84882641941
-
The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors
-
Tafforeau, L. et al. The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors. Mol. Cell 51, 539-551 (2013).
-
(2013)
Mol. Cell
, vol.51
, pp. 539-551
-
-
Tafforeau, L.1
-
39
-
-
0032553485
-
Requirement for p53 and p21 to sustain G2 arrest after DNA damage
-
Bunz, F. et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 282, 1497-1501 (1998).
-
(1998)
Science
, vol.282
, pp. 1497-1501
-
-
Bunz, F.1
-
40
-
-
67650303382
-
A complex assembly landscape for the 30S ribosomal subunit
-
Sykes, M. T. & Williamson, J. R. A complex assembly landscape for the 30S ribosomal subunit. Annu. Rev. Biophys. 38, 197-215 (2009).
-
(2009)
Annu. Rev. Biophys.
, vol.38
, pp. 197-215
-
-
Sykes, M.T.1
Williamson, J.R.2
-
41
-
-
35348939066
-
Assembly factors Rpf2 and Rrs1 recruit 5S rRNA and ribosomal proteins rpL5 and rpL11 into nascent ribosomes
-
Zhang, J. et al. Assembly factors Rpf2 and Rrs1 recruit 5S rRNA and ribosomal proteins rpL5 and rpL11 into nascent ribosomes. Genes Dev. 21, 2580-2592 (2007).
-
(2007)
Genes Dev.
, vol.21
, pp. 2580-2592
-
-
Zhang, J.1
-
42
-
-
0037363075
-
Does the ribosome translate cancer?
-
Ruggero, D. & Pandolfi, P. P. Does the ribosome translate cancer? Nat. Rev. Cancer 3, 179-192 (2003).
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 179-192
-
-
Ruggero, D.1
Pandolfi, P.P.2
-
43
-
-
84908150999
-
Nucleolar stress with and without p53
-
James, A., Wang, Y., Raje, H., Rosby, R. & DiMario, P. Nucleolar stress with and without p53. Nucleus 5, 402-426 (2014).
-
(2014)
Nucleus
, vol.5
, pp. 402-426
-
-
James, A.1
Wang, Y.2
Raje, H.3
Rosby, R.4
DiMario, P.5
-
44
-
-
84861170072
-
Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint
-
Fumagalli, S., Ivanenkov, V. V., Teng, T. & Thomas, G. Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint. Genes Dev. 26, 1028-1040 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 1028-1040
-
-
Fumagalli, S.1
Ivanenkov, V.V.2
Teng, T.3
Thomas, G.4
-
45
-
-
77955479087
-
Perturbation of 60S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation
-
Sun, X. X., Wang, Y. G., Xirodimas, D. P. & Dai, M. S. Perturbation of 60S ribosomal biogenesis results in ribosomal protein L5- and L11-dependent p53 activation. J. Biol. Chem. 285, 25812-25821 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 25812-25821
-
-
Sun, X.X.1
Wang, Y.G.2
Xirodimas, D.P.3
Dai, M.S.4
-
46
-
-
84870908454
-
Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress
-
Bursac, S. et al. Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress. Proc. Natl Acad. Sci. USA 109, 20467-20472 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 20467-20472
-
-
Bursac, S.1
-
47
-
-
77954404581
-
Defining the pathway of cytoplasmic maturation of the 60S ribosomal subunit
-
Lo, K. Y. et al. Defining the pathway of cytoplasmic maturation of the 60S ribosomal subunit. Mol. Cell 39, 196-208 (2010).
-
(2010)
Mol. Cell
, vol.39
, pp. 196-208
-
-
Lo, K.Y.1
-
48
-
-
26944450063
-
Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function
-
Ferreira-Cerca, S., Poll, G., Gleizes, P. E., Tschochner, H. & Milkereit, P. Roles of eukaryotic ribosomal proteins in maturation and transport of pre-18S rRNA and ribosome function. Mol. Cell 20, 263-275 (2005).
-
(2005)
Mol. Cell
, vol.20
, pp. 263-275
-
-
Ferreira-Cerca, S.1
Poll, G.2
Gleizes, P.E.3
Tschochner, H.4
Milkereit, P.5
-
49
-
-
83855162728
-
The structure of the eukaryotic ribosome at 3.0A resolution
-
Ben-Shem, A. et al. The structure of the eukaryotic ribosome at 3.0A resolution. Science 334, 1524-1529 (2011).
-
(2011)
Science
, vol.334
, pp. 1524-1529
-
-
Ben-Shem, A.1
-
50
-
-
84928786981
-
Structure of the human 80S ribosome
-
Khatter, H., Myasnikov, A. G., Natchiar, S. K. & Klaholz, B. P. Structure of the human 80S ribosome. Nature 520, 640-645 (2015).
-
(2015)
Nature
, vol.520
, pp. 640-645
-
-
Khatter, H.1
Myasnikov, A.G.2
Natchiar, S.K.3
Klaholz, B.P.4
-
51
-
-
84936990413
-
Chaperoning 5S RNA assembly
-
Madru, C. et al. Chaperoning 5S RNA assembly. Genes Dev. 29, 1432-1446 (2015).
-
(2015)
Genes Dev.
, vol.29
, pp. 1432-1446
-
-
Madru, C.1
-
52
-
-
84918590647
-
60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle
-
Leidig, C. et al. 60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle. Nat. Commun. 5, 3491 (2014).
-
(2014)
Nat. Commun.
, vol.5
, pp. 3491
-
-
Leidig, C.1
-
53
-
-
84918586987
-
A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation
-
Bassler, J. et al. A network of assembly factors is involved in remodeling rRNA elements during preribosome maturation. J. Cell Biol. 207, 481-498 (2014).
-
(2014)
J. Cell Biol.
, vol.207
, pp. 481-498
-
-
Bassler, J.1
-
54
-
-
0035805213
-
Crystal structure of the ribosome at 5.5A resolution
-
Yusupov, M. M. et al. Crystal structure of the ribosome at 5.5A resolution. Science 292, 883-896 (2001).
-
(2001)
Science
, vol.292
, pp. 883-896
-
-
Yusupov, M.M.1
-
55
-
-
0344011603
-
Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses
-
Rubbi, C. P. & Milner, J. Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses. EMBO J. 22, 6068-6077 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 6068-6077
-
-
Rubbi, C.P.1
Milner, J.2
-
56
-
-
64049107857
-
Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction
-
Fumagalli, S. et al. Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nat. Cell Biol. 11, 501-508 (2009).
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 501-508
-
-
Fumagalli, S.1
|