메뉴 건너뛰기




Volumn 109, Issue 50, 2012, Pages 20467-20472

Mutual protection of ribosomal proteins L5 and L11 from degradation is essential for p53 activation upon ribosomal biogenesis stress

Author keywords

Proteasome; Ribosomal stress

Indexed keywords

DACTINOMYCIN; DNA DIRECTED RNA POLYMERASE; PROMYELOCYTIC LEUKEMIA PROTEIN; PROTEASOME; PROTEIN MDM2; PROTEIN P53; RIBOSOMAL PROTEIN L11; RIBOSOMAL PROTEIN L5; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

EID: 84870908454     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1218535109     Document Type: Article
Times cited : (172)

References (39)
  • 1
    • 65349103899 scopus 로고    scopus 로고
    • Blinded by the light: The growing complexity of p53
    • Vousden KH, Prives C (2009) Blinded by the light: The growing complexity of p53. Cell 137(3):413-431.
    • (2009) Cell , vol.137 , Issue.3 , pp. 413-431
    • Vousden, K.H.1    Prives, C.2
  • 3
    • 77955382651 scopus 로고    scopus 로고
    • Clinical outcomes and correlates of TP53 mutations and cancer
    • Robles AI, Harris CC (2010) Clinical outcomes and correlates of TP53 mutations and cancer. Cold Spring Harb Perspect Biol 2(3):a001016.
    • (2010) Cold Spring Harb Perspect Biol , vol.2 , Issue.3
    • Robles, A.I.1    Harris, C.C.2
  • 5
    • 29144438951 scopus 로고    scopus 로고
    • Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response
    • DOI 10.1101/gad.359305
    • Sulic S, et al. (2005) Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response. Genes Dev 19(24):3070-3082. (Pubitemid 41798121)
    • (2005) Genes and Development , vol.19 , Issue.24 , pp. 3070-3082
    • Sulic, S.1    Panic, L.2    Barkic, M.3    Mercep, M.4    Uzelac, M.5    Volarevic, S.6
  • 6
    • 70350497397 scopus 로고    scopus 로고
    • Signaling to p53: Ribosomal proteins find their way
    • Zhang Y, Lu H (2009) Signaling to p53: Ribosomal proteins find their way. Cancer Cell 16(5):369-377.
    • (2009) Cancer Cell , vol.16 , Issue.5 , pp. 369-377
    • Zhang, Y.1    Lu, H.2
  • 7
    • 84856286957 scopus 로고    scopus 로고
    • Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
    • Golomb L, et al. (2012) Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis. Mol Cell 45(2):222-232.
    • (2012) Mol Cell , vol.45 , Issue.2 , pp. 222-232
    • Golomb, L.1
  • 9
    • 66249142352 scopus 로고    scopus 로고
    • The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival
    • Barkić M, et al. (2009) The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Mol Cell Biol 29(10):2489-2504.
    • (2009) Mol Cell Biol , vol.29 , Issue.10 , pp. 2489-2504
    • Barkić, M.1
  • 10
    • 77950988337 scopus 로고    scopus 로고
    • Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome
    • Pellagatti A, et al. (2010) Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome. Blood 115(13):2721-2723.
    • (2010) Blood , vol.115 , Issue.13 , pp. 2721-2723
    • Pellagatti, A.1
  • 11
    • 79952742330 scopus 로고    scopus 로고
    • The role of p53 in ribosomopathies
    • Fumagalli S, Thomas G (2011) The role of p53 in ribosomopathies. Semin Hematol 48 (2):97-105.
    • (2011) Semin Hematol , vol.48 , Issue.2 , pp. 97-105
    • Fumagalli, S.1    Thomas, G.2
  • 12
    • 7244238177 scopus 로고    scopus 로고
    • Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5
    • Dai MS, Lu H (2004) Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5. J Biol Chem 279(43):44475-44482.
    • (2004) J Biol Chem , vol.279 , Issue.43 , pp. 44475-44482
    • Dai, M.S.1    Lu, H.2
  • 13
    • 3242715867 scopus 로고    scopus 로고
    • Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation
    • DOI 10.1038/sj.emboj.7600247
    • Bhat KP, Itahana K, Jin A, Zhang Y (2004) Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation. EMBO J 23(12):2402-2412. (Pubitemid 38954847)
    • (2004) EMBO Journal , vol.23 , Issue.12 , pp. 2402-2412
    • Bhat, K.P.1    Itahana, K.2    Jin, A.3    Zhang, Y.4
  • 14
    • 0038724615 scopus 로고    scopus 로고
    • Regulation of HDM2 activity by the ribosomal protein L11
    • DOI 10.1016/S1535-6108(03)00134-X
    • Lohrum MA, Ludwig RL, Kubbutat MH, Hanlon M, Vousden KH (2003) Regulation of HDM2 activity by the ribosomal protein L11. Cancer Cell 3(6):577-587. (Pubitemid 36808652)
    • (2003) Cancer Cell , vol.3 , Issue.6 , pp. 577-587
    • Lohrum, M.A.E.1    Ludwig, R.L.2    Kubbutat, M.H.G.3    Hanlon, M.4    Vousden, K.H.5
  • 15
    • 0242721592 scopus 로고    scopus 로고
    • Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway
    • DOI 10.1128/MCB.23.23.8902-8912.2003
    • Zhang Y, et al. (2003) Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway. Mol Cell Biol 23 (23):8902-8912. (Pubitemid 37433388)
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.23 , pp. 8902-8912
    • Zhang, Y.1    Wolf, G.W.2    Bhat, K.3    Jin, A.4    Allio, T.5    Burkhart, W.A.6    Xiong, Y.7
  • 16
    • 4344685939 scopus 로고    scopus 로고
    • Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition
    • Dai MS, et al. (2004) Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition. Mol Cell Biol 24(17):7654-7668.
    • (2004) Mol Cell Biol , vol.24 , Issue.17 , pp. 7654-7668
    • Dai, M.S.1
  • 17
    • 4344660471 scopus 로고    scopus 로고
    • Inhibition of HDM2 and activation of p53 by ribosomal protein L23
    • DOI 10.1128/MCB.24.17.7669-7680.2004
    • Jin A, Itahana K, O'Keefe K, Zhang Y (2004) Inhibition of HDM2 and activation of p53 by ribosomal protein L23. Mol Cell Biol 24(17):7669-7680. (Pubitemid 39121492)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.17 , pp. 7669-7680
    • Jin, A.1    Itahana, K.2    O'Keefe, K.3    Zhang, Y.4
  • 18
    • 78049393990 scopus 로고    scopus 로고
    • Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26
    • Zhang Y, et al. (2010) Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26. Nucleic Acids Res 38(19):6544-6554.
    • (2010) Nucleic Acids Res , vol.38 , Issue.19 , pp. 6544-6554
    • Zhang, Y.1
  • 19
    • 34547620115 scopus 로고    scopus 로고
    • Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: Binding to MDM2, stabilization of p53 protein, and activation of p53 function
    • DOI 10.1038/sj.onc.1210327, PII 1210327
    • Chen D, et al. (2007) Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: Binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene 26(35):5029-5037. (Pubitemid 47206956)
    • (2007) Oncogene , vol.26 , Issue.35 , pp. 5029-5037
    • Chen, D.1    Zhang, Z.2    Li, M.3    Wang, W.4    Li, Y.5    Rayburn, E.R.6    Hill, D.L.7    Wang, H.8    Zhang, R.9
  • 20
    • 68349160548 scopus 로고    scopus 로고
    • Ribosomal protein S7 is both a regulator and a substrate of MDM2
    • Zhu Y, et al. (2009) Ribosomal protein S7 is both a regulator and a substrate of MDM2. Mol Cell 35(3):316-326.
    • (2009) Mol Cell , vol.35 , Issue.3 , pp. 316-326
    • Zhu, Y.1
  • 21
    • 53249142431 scopus 로고    scopus 로고
    • Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway
    • Horn HF, Vousden KH (2008) Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway. Oncogene 27(44):5774-5784.
    • (2008) Oncogene , vol.27 , Issue.44 , pp. 5774-5784
    • Horn, H.F.1    Vousden, K.H.2
  • 22
    • 64049107857 scopus 로고    scopus 로고
    • Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction
    • Fumagalli S, et al. (2009) Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nat Cell Biol 11(4):501-508.
    • (2009) Nat Cell Biol , vol.11 , Issue.4 , pp. 501-508
    • Fumagalli, S.1
  • 23
    • 84861170072 scopus 로고    scopus 로고
    • Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint
    • Fumagalli S, Ivanenkov VV, Teng T, Thomas G (2012) Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint. Genes Dev 26(10):1028-1040.
    • (2012) Genes Dev , vol.26 , Issue.10 , pp. 1028-1040
    • Fumagalli, S.1    Ivanenkov, V.V.2    Teng, T.3    Thomas, G.4
  • 24
    • 3042724637 scopus 로고    scopus 로고
    • Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis
    • DOI 10.1016/j.molcel.2004.05.020, PII S1097276504003065
    • Lapik YR, Fernandes CJ, Lau LF, Pestov DG (2004) Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis. Mol Cell 15(1):17-29. (Pubitemid 38850216)
    • (2004) Molecular Cell , vol.15 , Issue.1 , pp. 17-29
    • Lapik, Y.R.1    Fernandes, C.J.2    Lau, L.F.3    Pestov, D.G.4
  • 25
    • 50649096622 scopus 로고    scopus 로고
    • The role of human ribosomal proteins in the maturation of rRNA and ribosome production
    • Robledo S, et al. (2008) The role of human ribosomal proteins in the maturation of rRNA and ribosome production. RNA 14(9):1918-1929.
    • (2008) RNA , vol.14 , Issue.9 , pp. 1918-1929
    • Robledo, S.1
  • 26
    • 0037039159 scopus 로고    scopus 로고
    • Directed proteomic analysis of the human nucleolus
    • Andersen JS, et al. (2002) Directed proteomic analysis of the human nucleolus. Curr Biol 12(1):1-11.
    • (2002) Curr Biol , vol.12 , Issue.1 , pp. 1-11
    • Andersen, J.S.1
  • 27
    • 57349097152 scopus 로고    scopus 로고
    • Dynamic proteomics of individual cancer cells in response to a drug
    • Cohen AA, et al. (2008) Dynamic proteomics of individual cancer cells in response to a drug. Science 322(5907):1511-1516.
    • (2008) Science , vol.322 , Issue.5907 , pp. 1511-1516
    • Cohen, A.A.1
  • 28
    • 0035202090 scopus 로고    scopus 로고
    • Role of S6 phosphorylation and S6 kinase in cell growth
    • Volarević S, Thomas G (2001) Role of S6 phosphorylation and S6 kinase in cell growth. Prog Nucleic Acid Res Mol Biol 65:101-127.
    • (2001) Prog Nucleic Acid Res Mol Biol , vol.65 , pp. 101-127
    • Volarević, S.1    Thomas, G.2
  • 29
    • 0017760147 scopus 로고
    • In the absence of ribosomal RNA synthesis, the ribosomal proteins of HeLa cells are synthesized normally and degraded rapidly
    • Warner JR (1977) In the absence of ribosomal RNA synthesis, the ribosomal proteins of HeLa cells are synthesized normally and degraded rapidly. J Mol Biol 115(3):315-333.
    • (1977) J Mol Biol , vol.115 , Issue.3 , pp. 315-333
    • Warner, J.R.1
  • 30
    • 34247391127 scopus 로고    scopus 로고
    • Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins
    • DOI 10.1016/j.cub.2007.03.064, PII S096098220701202X
    • Lam YW, Lamond AI, Mann M, Andersen JS (2007) Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins. Curr Biol 17(9):749-760. (Pubitemid 46635118)
    • (2007) Current Biology , vol.17 , Issue.9 , pp. 749-760
    • Lam, Y.W.1    Lamond, A.I.2    Mann, M.3    Andersen, J.S.4
  • 32
    • 70449697971 scopus 로고    scopus 로고
    • Regulation of nucleolar signalling to p53 through NEDDylation of L11
    • Sundqvist A, Liu G, Mirsaliotis A, Xirodimas DP (2009) Regulation of nucleolar signalling to p53 through NEDDylation of L11. EMBO Rep 10(10):1132-1139.
    • (2009) EMBO Rep , vol.10 , Issue.10 , pp. 1132-1139
    • Sundqvist, A.1    Liu, G.2    Mirsaliotis, A.3    Xirodimas, D.P.4
  • 34
    • 35548950835 scopus 로고    scopus 로고
    • A nucleolar targeting signal in PML-I addresses PML to nucleolar caps in stressed or senescent cells
    • DOI 10.1242/jcs.007492
    • Condemine W, Takahashi Y, Le Bras M, de Thé H (2007) A nucleolar targeting signal in PML-I addresses PML to nucleolar caps in stressed or senescent cells. J Cell Sci 120(Pt 18):3219-3227. (Pubitemid 350018413)
    • (2007) Journal of Cell Science , vol.120 , Issue.18 , pp. 3219-3227
    • Condemine, W.1    Takahashi, Y.2    Le, B.M.3    De The, H.4
  • 35
    • 0035868964 scopus 로고    scopus 로고
    • p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
    • DOI 10.1093/emboj/20.6.1331
    • Ito A, et al. (2001) p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J 20(6):1331-1340. (Pubitemid 32233973)
    • (2001) EMBO Journal , vol.20 , Issue.6 , pp. 1331-1340
    • Ito, A.1    Lai, C.-H.2    Zhao, X.3    Saito, S.4    Hamilton, M.H.5    Appella, E.6    Yao, T.-P.7
  • 37
    • 77956518791 scopus 로고    scopus 로고
    • An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction
    • Macias E, et al. (2010) An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction. Cancer Cell 18(3):231-243.
    • (2010) Cancer Cell , vol.18 , Issue.3 , pp. 231-243
    • Macias, E.1
  • 38
    • 79960711067 scopus 로고    scopus 로고
    • The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells
    • Donati G, et al. (2011) The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells. Oncogene 30(29):3274-3288.
    • (2011) Oncogene , vol.30 , Issue.29 , pp. 3274-3288
    • Donati, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.