-
1
-
-
65349103899
-
Blinded by the light: The growing complexity of p53
-
Vousden KH, Prives C (2009) Blinded by the light: The growing complexity of p53. Cell 137(3):413-431.
-
(2009)
Cell
, vol.137
, Issue.3
, pp. 413-431
-
-
Vousden, K.H.1
Prives, C.2
-
3
-
-
77955382651
-
Clinical outcomes and correlates of TP53 mutations and cancer
-
Robles AI, Harris CC (2010) Clinical outcomes and correlates of TP53 mutations and cancer. Cold Spring Harb Perspect Biol 2(3):a001016.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, Issue.3
-
-
Robles, A.I.1
Harris, C.C.2
-
4
-
-
0034674714
-
Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6
-
DOI 10.1126/science.288.5473.2045
-
Volarevic S, et al. (2000) Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6. Science 288(5473):2045-2047. (Pubitemid 30397685)
-
(2000)
Science
, vol.288
, Issue.5473
, pp. 2045-2047
-
-
Volarevic, S.1
Stewart, M.J.2
Ledermann, B.3
Zilberman, F.4
Terracciano, L.5
Montini, E.6
Grompe, M.7
Kozma, S.C.8
Thomas, G.9
-
5
-
-
29144438951
-
Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response
-
DOI 10.1101/gad.359305
-
Sulic S, et al. (2005) Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response. Genes Dev 19(24):3070-3082. (Pubitemid 41798121)
-
(2005)
Genes and Development
, vol.19
, Issue.24
, pp. 3070-3082
-
-
Sulic, S.1
Panic, L.2
Barkic, M.3
Mercep, M.4
Uzelac, M.5
Volarevic, S.6
-
6
-
-
70350497397
-
Signaling to p53: Ribosomal proteins find their way
-
Zhang Y, Lu H (2009) Signaling to p53: Ribosomal proteins find their way. Cancer Cell 16(5):369-377.
-
(2009)
Cancer Cell
, vol.16
, Issue.5
, pp. 369-377
-
-
Zhang, Y.1
Lu, H.2
-
7
-
-
84856286957
-
Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis
-
Golomb L, et al. (2012) Importin 7 and exportin 1 link c-Myc and p53 to regulation of ribosomal biogenesis. Mol Cell 45(2):222-232.
-
(2012)
Mol Cell
, vol.45
, Issue.2
, pp. 222-232
-
-
Golomb, L.1
-
8
-
-
38949170601
-
Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function
-
DOI 10.1038/nm1725, PII NM1725
-
Jones NC, et al. (2008) Prevention of the neurocristopathy Treacher Collins syndrome through inhibition of p53 function. Nat Med 14(2):125-133. (Pubitemid 351214559)
-
(2008)
Nature Medicine
, vol.14
, Issue.2
, pp. 125-133
-
-
Jones, N.C.1
Lynn, M.L.2
Gaudenz, K.3
Sakai, D.4
Aoto, K.5
Rey, J.-P.6
Glynn, E.F.7
Ellington, L.8
Du, C.9
Dixon, J.10
Dixon, M.J.11
Trainor, P.A.12
-
9
-
-
66249142352
-
The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival
-
Barkić M, et al. (2009) The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Mol Cell Biol 29(10):2489-2504.
-
(2009)
Mol Cell Biol
, vol.29
, Issue.10
, pp. 2489-2504
-
-
Barkić, M.1
-
10
-
-
77950988337
-
Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome
-
Pellagatti A, et al. (2010) Induction of p53 and up-regulation of the p53 pathway in the human 5q- syndrome. Blood 115(13):2721-2723.
-
(2010)
Blood
, vol.115
, Issue.13
, pp. 2721-2723
-
-
Pellagatti, A.1
-
11
-
-
79952742330
-
The role of p53 in ribosomopathies
-
Fumagalli S, Thomas G (2011) The role of p53 in ribosomopathies. Semin Hematol 48 (2):97-105.
-
(2011)
Semin Hematol
, vol.48
, Issue.2
, pp. 97-105
-
-
Fumagalli, S.1
Thomas, G.2
-
12
-
-
7244238177
-
Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5
-
Dai MS, Lu H (2004) Inhibition of MDM2-mediated p53 ubiquitination and degradation by ribosomal protein L5. J Biol Chem 279(43):44475-44482.
-
(2004)
J Biol Chem
, vol.279
, Issue.43
, pp. 44475-44482
-
-
Dai, M.S.1
Lu, H.2
-
13
-
-
3242715867
-
Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation
-
DOI 10.1038/sj.emboj.7600247
-
Bhat KP, Itahana K, Jin A, Zhang Y (2004) Essential role of ribosomal protein L11 in mediating growth inhibition-induced p53 activation. EMBO J 23(12):2402-2412. (Pubitemid 38954847)
-
(2004)
EMBO Journal
, vol.23
, Issue.12
, pp. 2402-2412
-
-
Bhat, K.P.1
Itahana, K.2
Jin, A.3
Zhang, Y.4
-
14
-
-
0038724615
-
Regulation of HDM2 activity by the ribosomal protein L11
-
DOI 10.1016/S1535-6108(03)00134-X
-
Lohrum MA, Ludwig RL, Kubbutat MH, Hanlon M, Vousden KH (2003) Regulation of HDM2 activity by the ribosomal protein L11. Cancer Cell 3(6):577-587. (Pubitemid 36808652)
-
(2003)
Cancer Cell
, vol.3
, Issue.6
, pp. 577-587
-
-
Lohrum, M.A.E.1
Ludwig, R.L.2
Kubbutat, M.H.G.3
Hanlon, M.4
Vousden, K.H.5
-
15
-
-
0242721592
-
Ribosomal Protein L11 Negatively Regulates Oncoprotein MDM2 and Mediates a p53-Dependent Ribosomal-Stress Checkpoint Pathway
-
DOI 10.1128/MCB.23.23.8902-8912.2003
-
Zhang Y, et al. (2003) Ribosomal protein L11 negatively regulates oncoprotein MDM2 and mediates a p53-dependent ribosomal-stress checkpoint pathway. Mol Cell Biol 23 (23):8902-8912. (Pubitemid 37433388)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.23
, pp. 8902-8912
-
-
Zhang, Y.1
Wolf, G.W.2
Bhat, K.3
Jin, A.4
Allio, T.5
Burkhart, W.A.6
Xiong, Y.7
-
16
-
-
4344685939
-
Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition
-
Dai MS, et al. (2004) Ribosomal protein L23 activates p53 by inhibiting MDM2 function in response to ribosomal perturbation but not to translation inhibition. Mol Cell Biol 24(17):7654-7668.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.17
, pp. 7654-7668
-
-
Dai, M.S.1
-
17
-
-
4344660471
-
Inhibition of HDM2 and activation of p53 by ribosomal protein L23
-
DOI 10.1128/MCB.24.17.7669-7680.2004
-
Jin A, Itahana K, O'Keefe K, Zhang Y (2004) Inhibition of HDM2 and activation of p53 by ribosomal protein L23. Mol Cell Biol 24(17):7669-7680. (Pubitemid 39121492)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.17
, pp. 7669-7680
-
-
Jin, A.1
Itahana, K.2
O'Keefe, K.3
Zhang, Y.4
-
18
-
-
78049393990
-
Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26
-
Zhang Y, et al. (2010) Negative regulation of HDM2 to attenuate p53 degradation by ribosomal protein L26. Nucleic Acids Res 38(19):6544-6554.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.19
, pp. 6544-6554
-
-
Zhang, Y.1
-
19
-
-
34547620115
-
Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: Binding to MDM2, stabilization of p53 protein, and activation of p53 function
-
DOI 10.1038/sj.onc.1210327, PII 1210327
-
Chen D, et al. (2007) Ribosomal protein S7 as a novel modulator of p53-MDM2 interaction: Binding to MDM2, stabilization of p53 protein, and activation of p53 function. Oncogene 26(35):5029-5037. (Pubitemid 47206956)
-
(2007)
Oncogene
, vol.26
, Issue.35
, pp. 5029-5037
-
-
Chen, D.1
Zhang, Z.2
Li, M.3
Wang, W.4
Li, Y.5
Rayburn, E.R.6
Hill, D.L.7
Wang, H.8
Zhang, R.9
-
20
-
-
68349160548
-
Ribosomal protein S7 is both a regulator and a substrate of MDM2
-
Zhu Y, et al. (2009) Ribosomal protein S7 is both a regulator and a substrate of MDM2. Mol Cell 35(3):316-326.
-
(2009)
Mol Cell
, vol.35
, Issue.3
, pp. 316-326
-
-
Zhu, Y.1
-
21
-
-
53249142431
-
Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway
-
Horn HF, Vousden KH (2008) Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway. Oncogene 27(44):5774-5784.
-
(2008)
Oncogene
, vol.27
, Issue.44
, pp. 5774-5784
-
-
Horn, H.F.1
Vousden, K.H.2
-
22
-
-
64049107857
-
Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction
-
Fumagalli S, et al. (2009) Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nat Cell Biol 11(4):501-508.
-
(2009)
Nat Cell Biol
, vol.11
, Issue.4
, pp. 501-508
-
-
Fumagalli, S.1
-
23
-
-
84861170072
-
Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint
-
Fumagalli S, Ivanenkov VV, Teng T, Thomas G (2012) Suprainduction of p53 by disruption of 40S and 60S ribosome biogenesis leads to the activation of a novel G2/M checkpoint. Genes Dev 26(10):1028-1040.
-
(2012)
Genes Dev
, vol.26
, Issue.10
, pp. 1028-1040
-
-
Fumagalli, S.1
Ivanenkov, V.V.2
Teng, T.3
Thomas, G.4
-
24
-
-
3042724637
-
Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis
-
DOI 10.1016/j.molcel.2004.05.020, PII S1097276504003065
-
Lapik YR, Fernandes CJ, Lau LF, Pestov DG (2004) Physical and functional interaction between Pes1 and Bop1 in mammalian ribosome biogenesis. Mol Cell 15(1):17-29. (Pubitemid 38850216)
-
(2004)
Molecular Cell
, vol.15
, Issue.1
, pp. 17-29
-
-
Lapik, Y.R.1
Fernandes, C.J.2
Lau, L.F.3
Pestov, D.G.4
-
25
-
-
50649096622
-
The role of human ribosomal proteins in the maturation of rRNA and ribosome production
-
Robledo S, et al. (2008) The role of human ribosomal proteins in the maturation of rRNA and ribosome production. RNA 14(9):1918-1929.
-
(2008)
RNA
, vol.14
, Issue.9
, pp. 1918-1929
-
-
Robledo, S.1
-
26
-
-
0037039159
-
Directed proteomic analysis of the human nucleolus
-
Andersen JS, et al. (2002) Directed proteomic analysis of the human nucleolus. Curr Biol 12(1):1-11.
-
(2002)
Curr Biol
, vol.12
, Issue.1
, pp. 1-11
-
-
Andersen, J.S.1
-
27
-
-
57349097152
-
Dynamic proteomics of individual cancer cells in response to a drug
-
Cohen AA, et al. (2008) Dynamic proteomics of individual cancer cells in response to a drug. Science 322(5907):1511-1516.
-
(2008)
Science
, vol.322
, Issue.5907
, pp. 1511-1516
-
-
Cohen, A.A.1
-
28
-
-
0035202090
-
Role of S6 phosphorylation and S6 kinase in cell growth
-
Volarević S, Thomas G (2001) Role of S6 phosphorylation and S6 kinase in cell growth. Prog Nucleic Acid Res Mol Biol 65:101-127.
-
(2001)
Prog Nucleic Acid Res Mol Biol
, vol.65
, pp. 101-127
-
-
Volarević, S.1
Thomas, G.2
-
29
-
-
0017760147
-
In the absence of ribosomal RNA synthesis, the ribosomal proteins of HeLa cells are synthesized normally and degraded rapidly
-
Warner JR (1977) In the absence of ribosomal RNA synthesis, the ribosomal proteins of HeLa cells are synthesized normally and degraded rapidly. J Mol Biol 115(3):315-333.
-
(1977)
J Mol Biol
, vol.115
, Issue.3
, pp. 315-333
-
-
Warner, J.R.1
-
30
-
-
34247391127
-
Analysis of Nucleolar Protein Dynamics Reveals the Nuclear Degradation of Ribosomal Proteins
-
DOI 10.1016/j.cub.2007.03.064, PII S096098220701202X
-
Lam YW, Lamond AI, Mann M, Andersen JS (2007) Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins. Curr Biol 17(9):749-760. (Pubitemid 46635118)
-
(2007)
Current Biology
, vol.17
, Issue.9
, pp. 749-760
-
-
Lam, Y.W.1
Lamond, A.I.2
Mann, M.3
Andersen, J.S.4
-
31
-
-
11944274520
-
Nucleolar proteome dynamics
-
DOI 10.1038/nature03207
-
Andersen JS, et al. (2005) Nucleolar proteome dynamics. Nature 433(7021):77-83. (Pubitemid 40101146)
-
(2005)
Nature
, vol.433
, Issue.7021
, pp. 77-83
-
-
Andersen, J.S.1
Lam, Y.W.2
Leung, A.K.L.3
Ong, S.-E.4
Lyon, C.E.5
Lamond, A.I.6
Mann, M.7
-
32
-
-
70449697971
-
Regulation of nucleolar signalling to p53 through NEDDylation of L11
-
Sundqvist A, Liu G, Mirsaliotis A, Xirodimas DP (2009) Regulation of nucleolar signalling to p53 through NEDDylation of L11. EMBO Rep 10(10):1132-1139.
-
(2009)
EMBO Rep
, vol.10
, Issue.10
, pp. 1132-1139
-
-
Sundqvist, A.1
Liu, G.2
Mirsaliotis, A.3
Xirodimas, D.P.4
-
34
-
-
35548950835
-
A nucleolar targeting signal in PML-I addresses PML to nucleolar caps in stressed or senescent cells
-
DOI 10.1242/jcs.007492
-
Condemine W, Takahashi Y, Le Bras M, de Thé H (2007) A nucleolar targeting signal in PML-I addresses PML to nucleolar caps in stressed or senescent cells. J Cell Sci 120(Pt 18):3219-3227. (Pubitemid 350018413)
-
(2007)
Journal of Cell Science
, vol.120
, Issue.18
, pp. 3219-3227
-
-
Condemine, W.1
Takahashi, Y.2
Le, B.M.3
De The, H.4
-
35
-
-
0035868964
-
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2
-
DOI 10.1093/emboj/20.6.1331
-
Ito A, et al. (2001) p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J 20(6):1331-1340. (Pubitemid 32233973)
-
(2001)
EMBO Journal
, vol.20
, Issue.6
, pp. 1331-1340
-
-
Ito, A.1
Lai, C.-H.2
Zhao, X.3
Saito, S.4
Hamilton, M.H.5
Appella, E.6
Yao, T.-P.7
-
36
-
-
3242726103
-
PML regulates p53 stability by sequestering Mdm2 to the nucleolus
-
DOI 10.1038/ncb1147
-
Bernardi R, et al. (2004) PML regulates p53 stability by sequestering Mdm2 to the nucleolus. Nat Cell Biol 6(7):665-672. (Pubitemid 38960925)
-
(2004)
Nature Cell Biology
, vol.6
, Issue.7
, pp. 665-672
-
-
Bernardi, R.1
Scaglioni, P.P.2
Bergmann, S.3
Horn, H.F.4
Vousden, K.H.5
Pandolfi, P.P.6
-
37
-
-
77956518791
-
An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction
-
Macias E, et al. (2010) An ARF-independent c-MYC-activated tumor suppression pathway mediated by ribosomal protein-Mdm2 Interaction. Cancer Cell 18(3):231-243.
-
(2010)
Cancer Cell
, vol.18
, Issue.3
, pp. 231-243
-
-
Macias, E.1
-
38
-
-
79960711067
-
The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells
-
Donati G, et al. (2011) The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells. Oncogene 30(29):3274-3288.
-
(2011)
Oncogene
, vol.30
, Issue.29
, pp. 3274-3288
-
-
Donati, G.1
-
39
-
-
0027999512
-
The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes
-
Marechal V, Elenbaas B, Piette J, Nicolas JC, Levine AJ (1994) The ribosomal L5 protein is associated with mdm-2 and mdm-2-p53 complexes. Mol Cell Biol 14(11):7414-7420. (Pubitemid 24326406)
-
(1994)
Molecular and Cellular Biology
, vol.14
, Issue.11
, pp. 7414-7420
-
-
Marechal, V.1
Elenbaas, B.2
Piette, J.3
Nicolas, J.-C.4
Levine, A.J.5
|