Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development

EMBO Journal

Volumn 35, Issue 14, 2016, Pages 1550-1564

  Pedersen, Marianne Terndrup ^a,b   Kooistra, Susanne Marije ^a,b,e   Radzisheuskaya, Aliaksandra ^a,b   Laugesen, Anne ^a,b,c   Johansen, Jens Vilstrup ^a   Hayward, Daniel Geoffrey ^d   Nilsson, Jakob ^d   Agger, Karl ^a,b   Helin, Kristian ^a,b,c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c University of Copenhagen   (Denmark)

^d University of Copenhagen   (Denmark)

^e UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

development; epigenetics; histone demethylation; Kdm4; transcription

Indexed keywords

HISTONE DEMETHYLASE; HISTONE H3; JMJD2A PROTEIN; JMJD2B PROTEIN; JMJD2C PROTEIN; UNCLASSIFIED DRUG; HISTONE; JMJD2A PROTEIN, MOUSE; JMJD2C PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL DIFFERENTIATION; EMBRYO; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; ENDODERM; GENE TARGETING; HISTONE METHYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN LOCALIZATION; PROTEIN TARGETING; STEM CELL CULTURE; STEM CELL SELF-RENEWAL; ANIMAL; GENETICS; KNOCKOUT MOUSE; METABOLISM; METHYLATION; PHYSIOLOGY;

ANIMALS; EMBRYONIC STEM CELLS; HISTONE DEMETHYLASES; HISTONES; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; METHYLATION; MICE; MICE, KNOCKOUT; PROMOTER REGIONS, GENETIC;

EID: 84973334058     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201593317     Document Type: Article

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