-
1
-
-
84922797115
-
Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease
-
Blennow, K. et al. Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer's disease. Alzheimers Dement 11, 58-69 (2015).
-
(2015)
Alzheimers Dement
, vol.11
, pp. 58-69
-
-
Blennow, K.1
-
2
-
-
77949423619
-
Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
-
Blennow, K., Hampel, H., Weiner, M. & Zetterberg, H. Cerebrospinal fluid and plasma biomarkers in Alzheimer disease. Nat Rev Neurol 6, 131-144 (2010).
-
(2010)
Nat Rev Neurol
, vol.6
, pp. 131-144
-
-
Blennow, K.1
Hampel, H.2
Weiner, M.3
Zetterberg, H.4
-
3
-
-
84872379077
-
Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers
-
Jack, C. R. Jr. et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol 12, 207-216 (2013).
-
(2013)
Lancet Neurol
, vol.12
, pp. 207-216
-
-
Jack, C.R.1
-
4
-
-
84865529158
-
Clinical and biomarker changes in dominantly inherited Alzheimer's disease
-
Bateman, R. J. et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 367, 795-804 (2012).
-
(2012)
N Engl J Med
, vol.367
, pp. 795-804
-
-
Bateman, R.J.1
-
5
-
-
84855304100
-
Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia
-
Buchhave, P. et al. Cerebrospinal fluid levels of beta-amyloid 1-42, but not of tau, are fully changed already 5 to 10 years before the onset of Alzheimer dementia. Arch Gen Psychiatry 69, 98-106 (2012).
-
(2012)
Arch Gen Psychiatry
, vol.69
, pp. 98-106
-
-
Buchhave, P.1
-
6
-
-
84937758712
-
Amyloid biomarkers in Alzheimer's disease
-
Blennow, K., Mattsson, N., Scholl, M., Hansson, O. & Zetterberg, H. Amyloid biomarkers in Alzheimer's disease. Trends Pharmacol Sci 36, 297-309 (2015).
-
(2015)
Trends Pharmacol Sci
, vol.36
, pp. 297-309
-
-
Blennow, K.1
Mattsson, N.2
Scholl, M.3
Hansson, O.4
Zetterberg, H.5
-
7
-
-
84900988440
-
Advancing research diagnostic criteria for Alzheimer's disease: The IWG-2 criteria
-
Dubois, B. et al. Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria. Lancet Neurol 13, 614-629 (2014).
-
(2014)
Lancet Neurol
, vol.13
, pp. 614-629
-
-
Dubois, B.1
-
8
-
-
79956142378
-
The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
McKhann, G. M. et al. The diagnosis of dementia due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 263-269 (2011).
-
(2011)
Alzheimers Dement
, vol.7
, pp. 263-269
-
-
McKhann, G.M.1
-
9
-
-
84891073424
-
Developing novel blood-based biomarkers for Alzheimer's disease
-
Snyder, H. M. et al. Developing novel blood-based biomarkers for Alzheimer's disease. Alzheimers Dement 10, 109-114 (2014).
-
(2014)
Alzheimers Dement
, vol.10
, pp. 109-114
-
-
Snyder, H.M.1
-
10
-
-
33947282076
-
Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease
-
Graff-Radford, N. R. et al. Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Archives of neurology 64, 354-362 (2007).
-
(2007)
Archives of Neurology
, vol.64
, pp. 354-362
-
-
Graff-Radford, N.R.1
-
11
-
-
52949118083
-
Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease
-
Schupf, N. et al. Peripheral Abeta subspecies as risk biomarkers of Alzheimer's disease. Proc Natl Acad Sci USA 105, 14052-14057 (2008).
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 14052-14057
-
-
Schupf, N.1
-
12
-
-
80054705807
-
Factors affecting Abeta plasma levels and their utility as biomarkers in ADNI
-
Toledo, J. B. et al. Factors affecting Abeta plasma levels and their utility as biomarkers in ADNI. Acta Neuropathol 122, 401-413 (2011).
-
(2011)
Acta Neuropathol
, vol.122
, pp. 401-413
-
-
Toledo, J.B.1
-
13
-
-
33745959062
-
Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: A prospective case-cohort study
-
van Oijen, M., Hofman, A., Soares, H. D., Koudstaal, P. J. & Breteler, M. M. Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol 5, 655-660 (2006).
-
(2006)
Lancet Neurol
, vol.5
, pp. 655-660
-
-
Van Oijen, M.1
Hofman, A.2
Soares, H.D.3
Koudstaal, P.J.4
Breteler, M.M.5
-
14
-
-
84891167140
-
Association of plasma and cortical amyloid beta is modulated by APOE epsilon4 status
-
Swaminathan, S. et al. Association of plasma and cortical amyloid beta is modulated by APOE epsilon4 status. Alzheimers Dement 10, e9-e18 (2014).
-
(2014)
Alzheimers Dement
, vol.10
, pp. e9-e18
-
-
Swaminathan, S.1
-
15
-
-
84891163157
-
Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease
-
Rembach, A. et al. Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease. Alzheimers Dement 10, 53-61 (2014).
-
(2014)
Alzheimers Dement
, vol.10
, pp. 53-61
-
-
Rembach, A.1
-
16
-
-
77953246142
-
Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations
-
Rissin, D. M. et al. Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations. Nat Biotechnol 28, 595-599 (2010).
-
(2010)
Nat Biotechnol
, vol.28
, pp. 595-599
-
-
Rissin, D.M.1
-
17
-
-
84903579643
-
Cerebrospinal fluid analysis in Alzheimer's disease: Technical issues and future developments
-
Lista, S., Zetterberg, H., Dubois, B., Blennow, K. & Hampel, H. Cerebrospinal fluid analysis in Alzheimer's disease: technical issues and future developments. J Neurol 261, 1234-1243 (2014).
-
(2014)
J Neurol
, vol.261
, pp. 1234-1243
-
-
Lista, S.1
Zetterberg, H.2
Dubois, B.3
Blennow, K.4
Hampel, H.5
-
19
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of department of health and human services task force on Alzheimer's disease
-
McKhann, G. et al. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944 (1984).
-
(1984)
Neurology
, vol.34
, pp. 939-944
-
-
McKhann, G.1
-
20
-
-
84907978955
-
Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid beta-amyloid 42: A crossvalidation study against amyloid positron emission tomography
-
Palmqvist, S. et al. Accuracy of brain amyloid detection in clinical practice using cerebrospinal fluid beta-amyloid 42: a crossvalidation study against amyloid positron emission tomography. JAMA neurology 71, 1282-1289 (2014).
-
(2014)
JAMA Neurology
, vol.71
, pp. 1282-1289
-
-
Palmqvist, S.1
-
21
-
-
84872290209
-
Validation of a multiplex assay for simultaneous quantification of amyloid-beta peptide species in human plasma with utility for measurements in studies of Alzheimer's disease therapeutics
-
Lachno, D. R. et al. Validation of a multiplex assay for simultaneous quantification of amyloid-beta peptide species in human plasma with utility for measurements in studies of Alzheimer's disease therapeutics. J Alzheimers Dis 32, 905-918 (2012).
-
(2012)
J Alzheimers Dis
, vol.32
, pp. 905-918
-
-
Lachno, D.R.1
-
22
-
-
60349123096
-
Performance characteristics of plasma amyloid-beta 40 and 42 assays
-
Okereke, O. I. et al. Performance characteristics of plasma amyloid-beta 40 and 42 assays. J Alzheimers Dis 16, 277-285 (2009).
-
(2009)
J Alzheimers Dis
, vol.16
, pp. 277-285
-
-
Okereke, O.I.1
-
23
-
-
84973292723
-
CSF Aβ 42/Aβ 40 and Aβ 42/Aβ 38 ratios: Better diagnostic markers of Alzheimer disease
-
(In press)
-
Janelidze, S. et al. CSF Aβ 42/Aβ 40 and Aβ 42/Aβ 38 ratios: better diagnostic markers of Alzheimer disease. Annals of Clinical and Translational Neurology (In press).
-
Annals of Clinical and Translational Neurology
-
-
Janelidze, S.1
-
24
-
-
84943227798
-
Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease
-
Palmqvist, S. et al. Detailed comparison of amyloid PET and CSF biomarkers for identifying early Alzheimer disease. Neurology 85, 1240-1249 (2015).
-
(2015)
Neurology
, vol.85
, pp. 1240-1249
-
-
Palmqvist, S.1
-
25
-
-
66149104129
-
Whole-body biodistribution and radiation dosimetry of 18F-GE067: A radioligand for in vivo brain amyloid imaging
-
Koole, M. et al. Whole-body biodistribution and radiation dosimetry of 18F-GE067: a radioligand for in vivo brain amyloid imaging. J Nucl Med 50, 818-822 (2009).
-
(2009)
J Nucl Med
, vol.50
, pp. 818-822
-
-
Koole, M.1
-
26
-
-
84881461022
-
Implementation and validation of an adaptive template registration method for 18F-flutemetamol imaging data
-
Lundqvist, R. et al. Implementation and validation of an adaptive template registration method for 18F-flutemetamol imaging data. J Nucl Med 54, 1472-1478 (2013).
-
(2013)
J Nucl Med
, vol.54
, pp. 1472-1478
-
-
Lundqvist, R.1
-
27
-
-
0034986196
-
A new rating scale for age-related white matter changes applicable to MRI and CT
-
Wahlund, L. O. et al. A new rating scale for age-related white matter changes applicable to MRI and CT. Stroke; a journal of cerebral circulation 32, 1318-1322 (2001).
-
(2001)
Stroke; A Journal of Cerebral Circulation
, vol.32
, pp. 1318-1322
-
-
Wahlund, L.O.1
-
28
-
-
73349095046
-
The microbleed anatomical rating scale (MARS): Reliability of a tool to map brain microbleeds
-
Gregoire, S. M. et al. The Microbleed Anatomical Rating Scale (MARS): reliability of a tool to map brain microbleeds. Neurology 73, 1759-1766 (2009).
-
(2009)
Neurology
, vol.73
, pp. 1759-1766
-
-
Gregoire, S.M.1
-
29
-
-
84907805707
-
Apolipoprotein e genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease
-
Lautner, R. et al. Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease. JAMA Psychiatry 71, 1183-1191 (2014).
-
(2014)
JAMA Psychiatry
, vol.71
, pp. 1183-1191
-
-
Lautner, R.1
-
30
-
-
84927175748
-
APOE epsilon4: The most prevalent yet understudied risk factor for Alzheimer's disease
-
Michaelson, D. M. APOE epsilon4: the most prevalent yet understudied risk factor for Alzheimer's disease. Alzheimers Dement 10, 861-868 (2014).
-
(2014)
Alzheimers Dement
, vol.10
, pp. 861-868
-
-
Michaelson, D.M.1
-
31
-
-
84940769248
-
Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects
-
Toledo, J. B. et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain : a journal of neurology 138, 2701-2715 (2015).
-
(2015)
Brain : A Journal of Neurology
, vol.138
, pp. 2701-2715
-
-
Toledo, J.B.1
-
32
-
-
74149089257
-
Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment
-
Hansson, O. et al. Evaluation of plasma Abeta(40) and Abeta(42) as predictors of conversion to Alzheimer's disease in patients with mild cognitive impairment. Neurobiol Aging 31, 357-367 (2010).
-
(2010)
Neurobiol Aging
, vol.31
, pp. 357-367
-
-
Hansson, O.1
-
33
-
-
77952548703
-
Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing
-
Lewczuk, P. et al. Amyloid beta peptides in plasma in early diagnosis of Alzheimer's disease: A multicenter study with multiplexing. Exp Neurol 223, 366-370 (2010).
-
(2010)
Exp Neurol
, vol.223
, pp. 366-370
-
-
Lewczuk, P.1
-
34
-
-
0242412140
-
Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: Relation to age, mortality, and risk
-
Mayeux, R. et al. Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology 61, 1185-1190 (2003).
-
(2003)
Neurology
, vol.61
, pp. 1185-1190
-
-
Mayeux, R.1
-
35
-
-
84855759192
-
Evaluation of plasma Abeta as predictor of Alzheimer's disease in older individuals without dementia: A population-based study
-
Hansson, O. et al. Evaluation of plasma Abeta as predictor of Alzheimer's disease in older individuals without dementia: a population-based study. J Alzheimers Dis 28, 231-238 (2012).
-
(2012)
J Alzheimers Dis
, vol.28
, pp. 231-238
-
-
Hansson, O.1
-
36
-
-
33746291599
-
Plasma levels of beta-amyloid (1-42) in Alzheimer's disease and mild cognitive impairment
-
Pesaresi, M. et al. Plasma levels of beta-amyloid (1-42) in Alzheimer's disease and mild cognitive impairment. Neurobiol Aging 27, 904-905 (2006).
-
(2006)
Neurobiol Aging
, vol.27
, pp. 904-905
-
-
Pesaresi, M.1
-
37
-
-
1642390437
-
Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions
-
van Dijk, E. J. et al. Plasma amyloid beta, apolipoprotein E, lacunar infarcts, and white matter lesions. Ann Neurol 55, 570-575 (2004).
-
(2004)
Ann Neurol
, vol.55
, pp. 570-575
-
-
Van Dijk, E.J.1
-
38
-
-
58049155245
-
Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease
-
Roher, A. E. et al. Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease. Alzheimers Dement 5, 18-29 (2009).
-
(2009)
Alzheimers Dement
, vol.5
, pp. 18-29
-
-
Roher, A.E.1
-
39
-
-
33645829647
-
Plasma beta-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy
-
Gurol, M. E. et al. Plasma beta-amyloid and white matter lesions in AD, MCI, and cerebral amyloid angiopathy. Neurology 66, 23-29 (2006).
-
(2006)
Neurology
, vol.66
, pp. 23-29
-
-
Gurol, M.E.1
-
40
-
-
0042387969
-
Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation
-
Paris, D. et al. Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: role of inflammation. Neurol Res 25, 642-651 (2003).
-
(2003)
Neurol Res
, vol.25
, pp. 642-651
-
-
Paris, D.1
-
41
-
-
67349142021
-
Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
-
Bell, R. D. & Zlokovic, B. V. Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol 118, 103-113 (2009).
-
(2009)
Acta Neuropathol
, vol.118
, pp. 103-113
-
-
Bell, R.D.1
Zlokovic, B.V.2
-
42
-
-
0034603619
-
Cleavage of amyloid precursor protein elicited by chronic cerebral hypoperfusion
-
Bennett, S. A. et al. Cleavage of amyloid precursor protein elicited by chronic cerebral hypoperfusion. Neurobiol Aging 21, 207-214 (2000).
-
(2000)
Neurobiol Aging
, vol.21
, pp. 207-214
-
-
Bennett, S.A.1
-
43
-
-
83355176479
-
Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid beta levels in humans
-
Zetterberg, H. et al. Hypoxia due to cardiac arrest induces a time-dependent increase in serum amyloid beta levels in humans. PLoS One 6, e28263 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e28263
-
-
Zetterberg, H.1
-
44
-
-
0346848893
-
Hereditary cerebral hemorrhage with amyloidosis Dutch type (AbetaPP 693): Decreased plasma amyloid-beta 42 concentration
-
Bornebroek, M. et al. Hereditary cerebral hemorrhage with amyloidosis Dutch type (AbetaPP 693): decreased plasma amyloid-beta 42 concentration. Neurobiol Dis 14, 619-623 (2003).
-
(2003)
Neurobiol Dis
, vol.14
, pp. 619-623
-
-
Bornebroek, M.1
-
45
-
-
0034062254
-
Plasma beta-amyloid peptide, transforming growth factor-beta 1, and risk for cerebral amyloid angiopathy
-
Greenberg, S. M. et al. Plasma beta-amyloid peptide, transforming growth factor-beta 1, and risk for cerebral amyloid angiopathy. Ann N Y Acad Sci 903, 144-149 (2000).
-
(2000)
Ann N y Acad Sci
, vol.903
, pp. 144-149
-
-
Greenberg, S.M.1
-
46
-
-
84860221271
-
Plasma beta-amyloid levels in cerebral amyloid angiopathy-associated hemorrhagic stroke
-
Hernandez-Guillamon, M. et al. Plasma beta-amyloid levels in cerebral amyloid angiopathy-associated hemorrhagic stroke. Neurodegener Dis 10, 320-323 (2012).
-
(2012)
Neurodegener Dis
, vol.10
, pp. 320-323
-
-
Hernandez-Guillamon, M.1
-
47
-
-
79954548088
-
Association of plasma Ass peptides with blood pressure in the elderly
-
Lambert, J. C. et al. Association of plasma Ass peptides with blood pressure in the elderly. PLoS One 6, e18536 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e18536
-
-
Lambert, J.C.1
-
48
-
-
84924673615
-
Amyloid-beta (1-40) and the risk of death from cardiovascular causes in patients with coronary heart disease
-
Stamatelopoulos, K. et al. Amyloid-beta (1-40) and the risk of death from cardiovascular causes in patients with coronary heart disease. J Am Coll Cardiol 65, 904-916 (2015).
-
(2015)
J Am Coll Cardiol
, vol.65
, pp. 904-916
-
-
Stamatelopoulos, K.1
-
49
-
-
84897108729
-
A blood-based predictor for neocortical Abeta burden in Alzheimer's disease: Results from the AIBL study
-
Burnham, S. C. et al. A blood-based predictor for neocortical Abeta burden in Alzheimer's disease: results from the AIBL study. Mol Psychiatry 19, 519-526 (2014).
-
(2014)
Mol Psychiatry
, vol.19
, pp. 519-526
-
-
Burnham, S.C.1
-
50
-
-
84898447902
-
Plasma phospholipids identify antecedent memory impairment in older adults
-
Mapstone, M. et al. Plasma phospholipids identify antecedent memory impairment in older adults. Nature medicine 20, 415-418 (2014).
-
(2014)
Nature Medicine
, vol.20
, pp. 415-418
-
-
Mapstone, M.1
|